Publication Topic

Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D. 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Urban J, Budinsky R, Rowlands J. 2012. An evaluation of single nucleotide polymorphisms in the human heat shock protein 90kDa alpha and beta isoforms. Drug Metab Pharmacokinet 27(2):268-278; doi: 10.2133/dmpk.DMPK-11-SC-114. PMID: 22185817.

Rowlands JC, Urban JD, Wikoff DS, Budinsky RA. 2011. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene. Drug Metab Pharmacokinet 26(4):431-439; doi: 10.2133/dmpk.DMPK-11-SC-013. PMID: 21512261.

Proctor D, Haws L, Thompson C, Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

Hart BR, Mishra PK, Lintner RE, Hinerman JM, Herr AB, Blumenthal RM. 2011. Recognition of DNA by the helix-turn-helix global regulatory protein Lrp is modulated by the amino terminus. J Bacteriol 193(15):3794–3803; doi: 10.1128/jb.00191-11. PMID: 21642464.

Hao W, Jolliet O, Jiang X , Chang C-W, Towey T, Wenger Y, Garabrant D, Franzblau A, et al. The University of Michigan Dioxin Exposure Study: A pharmacokinetic modeling approach to investigate the predictors of serum TCDD concentration. Presented at the 31st International Symposium on Halogenated Persistent Organic Pollutants – Dioxin 2010, San Antonio, TX, September 2010.

Thompson CM, Johns DO, Sonawane S, Barton HA, Hattis D, Tardif R, Krishnan K. 2009. Database for physiologically based pharmacokinetic (PBPK) modeling: Physiological parameters for healthy and health-impaired elderly. J Toxicol Environ Health B 12(1):1–24; doi: 10.1080/10937400802545060. PMID: 19117207.

Jolliet O, Jiang X, Wenger Y, Milbrath MO, Chang C-W, Chen Q, Hong B, Hedgeman E, et al. 2008. Model formats and use of pharmacokinetic modeling for the statistical analysis of blood dioxin concentrations. Organohalogen Compounds 70:102–105.

Thompson CM, Sonawane B, Barton HA, DeWoskin RS, Schlosser P, Lipscomb JC, Chiu W, Krishnan K. 2008. Approaches for applications of physiologically based pharmacokinetic models in risk assessment. J Toxicol Environ Health B 11(7):519–547; doi: 10.1080/10937400701724337. PMID: 18584453.

Jolliet O, Wenger Y, Adriaens P, Chang C-W, Chen Q,…, Jiang X, Knutson K,…, Reichert H, et al. Explaining age dependency using pharmacokinetic modeling in the analysis of blood TCDD concentrations. Dioxin 2008 Conference, Birmingham, England, August 1, 2008.

Emond C, Raymer J, Garner E, Diliberto J, Staskal D, Birnbaum LS. A physiologically-based pharmacokinetic model for developmental exposure to PBDE-47 in rodents. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.

Rose WC, Marathe PH, Jang G, Monticello TM, Balasubramanian BN, Long B, Fairchild C, Wall ME, Wani MC. 2006. Novel fluoro-substituted campthothecins: In vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization. Cancer Chemother Pharmacol 58(1):73-85; doi: 10.1007/s00280-005-0128-y. PMID: 16228206.

Thompson CM, Capdevila JH, Strobel HW. 2000. Recombinant P450 2D18 metabolism of dopamine and arachidonic acid. J Pharmacol Exper Ther 294(3):1120–1130; doi: 10.1016/S0022-3565(24)39180-3. PMID: 10945868.

Rish W, Kirman CR, Hays SM, Gargas ML, Andersen ME, Reitz RH, Guengerich FP, Green T, McConnell EE, Buckpit A, Voytek P, Dugard PH. 1999. Developing a physiologically based pharmacokinetic model to describe methylene chloride kinetics at the subcellular level. Toxicologist 48, Paper No. 671. Presented at Society of Toxicology 38th Annual Meeting, New Orleans, LA, March 1999.