Publication Topic

Wikoff D. Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.

Wikoff D. Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.

Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA. 2025. Systematic evaluation of the evidence base on methyl tert-butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224. PMID: 40084233.

Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE. 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030. PMID: 39873747.

Schaefer HR, Vincent MJ, Burns CJ, Lange SS. 2025. Increasing the utility of epidemiologic studies as key evidence in chemical risk assessment. Toxicol Sci 203(2):166-170; doi: 10.1093/toxsci/kfae134. PMID: 39657235.

Firman JW, Boobis A, Hollnagel HM, Kaiser S, Lovell DP, Moretto A, Muller S,…, Patlewicz G. 2024. Evaluating the consistency of judgements derived through both in silico and expert application of the Cramer classification scheme. Food Chem Toxicol 194(Dec):115070; doi: 10.1016/j.fct.2024.115070. PMID: 39447833.

Mattes RD, Rivera BN, Rutigliani GR, Rogers S, Mendoza ID, Wang L, Beckemeier K, Wikoff D. 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723.

Bare J, Kennedy SB, Feifarek D, Panko J. Quality and reliability evaluation of 6PPD-quinone surface water occurrence data and considerations for use in risk assessment. Abstract 4.22.P-Mo-119, Society of Environmental Toxicology and Chemistry 45^th Annual Meeting, Fort Worth, TX, October 2024.

Reynolds JI, Choi J, Johnson BP. 2024. Crowdsourcing AOP development: Leveraging the thesis literature review to identify knowledge gaps and facilitate research translation. Curr Res Toxicol 7(Aug 8):100191; doi: 10.1016/j.crtox.2024.100191. PMID: 39205829.

Rudisill C, Jacobs M, Roy M, Brown L, Eaton R, Malloy T, Davies H, Tickner JT. 2024. The use of alternatives assessment in chemicals management policies: Needs for greater impact. Integr Environ Assess Manag 20(4):1035-1045; doi: 10.1002/ieam.4826. PMID: 37658263.

Eturki M, Davis KG, Vincent M, Arnold SF, Maier A. 2024. Micro-environmental factors impact breathing zone exposures: A simulated petrochemical manufacturing facility task. Arch Environ Occup Health 79(1):11–22; doi: 10.1080/19338244.2024.2328523. PMID: 38555729.

Ierardi AM, Burns A, Urban A, Finley B. 2024. A risk assessment of cosmetic talc for the development of mesothelioma and ovarian cancer. Chapter 13 in: Paustenbach DJ (ed), Human and Ecological Risk Assessment: Theory and Practice, Third Edition. Wiley, ISBN: 978-1-119-74296-8, pp. 541–570.

Burns AM, Ierardi AM. Risk evaluation of inhaled particulates during pressed powder makeup application. Abstract 3602, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Schaefer H. Introduction: Challenges associated with the use of epidemiologic studies in chemical risk assessments. Abstract 1295, Society of Toxicology 63^rd Annual Meeting, Salt Lake City, UT, 2024.

Schaefer H. Capturing unknowns: Increasing utility of epidemiologic studies as key evidence in chemical risk assessment. Abstract 1294, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, 2024.

Lynn SG, Lea IA, Urban J, Borghoff SJ, Wikoff D, Fitch S, Perry C, Choksi N, Britt J, Heintz M, Klaren W, et al. Development and application of systematic approach to inventory and interrogate thyroid hormone network information. Abstract 4357, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. 

Allen B, Vincent M, Lipworth L, Panko J, Suh M, Jiang X, Mumma MT, Proctor D. Lung cancer risk and exposure to hexavalent chromium: Results of extended mortality study of workers with low level exposures and quantitative risk assessment using pooled analysis of three cohorts. Poster presentation at Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Chang D, Cowden J, Davidson-Fritz S, Dean J, Devito M, Everett L, Harrill A,.., Patlewicz G, et al. 2024. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). EPA/600/X-23/084. U.S. Environmental Protection Agency: Washington, DC; doi: 10.23645/epacomptox.25365550.

Brennan A, Chang D, Cowden J, Davidson-Fritz S, Dean J, Devito M, Ford J, … , Patlewicz G, et al. 2024. EPA Transcriptomic Assessment Product (ETAP) for Perfluoro-3-Methoxypropanoic Acid. EPA/600/X-24/066. U.S. Environmental Protection Agency: Washington, DC; doi: 10.23645/epacomptox.25352962.

Racz L, Mittal L, Perry CS, Blanchette A, Proctor D. Assessing sustainable applications of electric arc furnace steel slag as construction aggregate: Applications of probabilistic risk assessment and physiologically-based pharmacokinetic modeling. Poster presented at Society of Environmental Toxicology and Chemistry North America 44^th Annual Meeting, Louisville, KY, November 2023.