Publication Topic

Ulrich, K. Requirements of nonclinical inhalation studies for clinical development and registration. Presentation to British Society of Toxicological Pathologists (BSTP) — Continuing Education Symposium 4, Department of Pathology, Cambridge, UK, 2015.

Hughes BJ, LeBaron MJ, Thomas J, Kan HL, Lynch AM, Borghoff SJ, Green S, Mensing T, Sarang SS, Smulders CJGM. 2015. Activation of CAR and PXR nuclear receptors in the liver of MIBK-exposed mice. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Society of Toxicology, Central States Regional Chapter Annual Meeting, Kansas City, KS, 2015.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Superfund Annual Meeting, San Juan, Puerto Rico, 2015.

Unice KM, Bare JL, Kreider ML, Panko JM. Evaluation of leachate from tire and road wear particles (TRWP) upflow percolation column tests. Poster at Society of Environmental Toxicology and Chemistry, 36th Annual Meeting, Salt Lake City, UT, November 1–5, 2015.

Young RR, Thompson CM, Dinesdurage HR, Elbekai RH, Suh M, Rohr AC, Proctor DM. 2015. A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats. Environ Mol Mutagen 56(7):629-636; doi: 10.1002/em.21951.

Borghoff SJ, Poet TS, Green S, Davis J, Hughes B, Mensing T, Sarang SS, Lynch AM, Hard GC.  2015. Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding. Toxicol 333(2015 July 3):1-13; doi: 10.1016/j.tox.2015.02.003.

Heintz MM, Brander SM, White JW. 2015. Endocrine disrupting compounds alter risk-taking behavior in guppies (Poecilia reticulata). Ethology 121(5):480–491; doi: 10.1111/eth.12362.

Unice KM, Bare JL, Kreider ML, Panko JM. 2015. Evaluation of leachate from tire and road wear particles (TRWP) upflow percolation column tests. Poster Presentation at Society of Environmental Toxicology and Chemistry (SETAC) North America 36th Annual Meeting, Salt Lake City, UT, November 2015.

Bottomley A, Prior H, Cordes J. Global cross-company data-sharing on the housing of non-rodents during the recording of cardiovascular telemetry data on safety pharmacology and toxicology studies. Poster presented at Safety Pharmacology Society, Prague, September 2015.

Bottomley AL, Rowles A, Mitchell DJ, Rasmussen AD. 2015. Detection of mild and reversible neurohistopathological changes in the brain of juvenile (preweaned) beagle dogs treated with vigabatrin for up to 91 days. Toxicol Pathol 43(7).

Strickland J, Choksi NY, Allen DG, Casey W. In silico predictions of skin sensitization using oecd qsar toolbox. Poster presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Auerbach SS, Choksi NY, Ferguson S, Hsieh J, Svboda DL, Myatt GJ, et al. HTS and SAR analysis of chemicals from the elk river spill. Poster presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Wikoff D, Thompson C, Perry C, White M, Borghoff S, Fitzgerald L, Haws LC. 2014. Development of toxicity values and exposure estimates for tetrabromobisphenol A [TBBPA]: Application in a margin of exposure assessment. J Appl Toxicol 35(11):1292-1308. doi: 10.1002/jat.3132.

Fitzgerald L, Wikoff DS. 2014. Persistent organic pollutants. In: Wexler P (Ed.), Encyclopedia of Toxicology, 3rd edition, vol 3. Elsevier, Inc., Academic Press, pp. 820-825.

Borghoff SJ, Hard GC, Poet TS, Davis J, Green S, Hughes B, Mensing T, Sarang SS. Methyl isobutyl ketone (MIBK) induces an exposure-related increase in measures of a2u-globulin (a2u) nephropath in male but not female F344 rats. Presented at the Society of Toxicology’s 53rd Annual Meeting, Phoenix, AZ, March 2014.

Wirbisky SE, Weber GJ, Lee JW, Cannon JR, Freeman JL. 2014. Novel dose-dependent alterations in excitatory GABA during embryonic development associated with lead (Pb) neurotoxicity. Toxicol Lett 229:1–8.

Panko JM. Chemical selection tools analysis project and results. Presented at GlobalChem. Global Chemical Regulations Conference, Baltimore, MD, March 2014.

Faber W, Kirkpatrick D, Coder P, Li P, Borghoff S, Banton M. 2014. Subchronic, reproductive, and maternal toxicity studies with tertiary butyl acetate (TBAC). Regul Toxicol Pharmacol 68:332-342.

Christian WV, Oliver LD, Paustenbach DJ, Kreider ML, Finley BL. 2014. Toxicology-based cancer causation analysis of CoCr-containing hip implants: A quantitative assessment of genotoxicity and tumorigenicity studies. J Appl Toxicol 34(9):939–967.