2018 (56 POSTS)
Kovochich M, Fung D, Unice KM, Mahoney SL, Paustenbach DJ, Finley BL . Understanding divergent outcomes in MoM-THA patient populations with well-fixed components: A critical appraisal of patient management protocols and revision trends (2000-2017). Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
Kovochich M, Fung ES, Mahoney SL, Unice KM, Fung D, Paustenbach DJ, Finley BL . Characterizing cytotoxic and inflammatory responses to metal-on-metal wear debris from normal versus edge-loading conditions. Poster presentation at Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.
Publication: Abstracts and Presentations
Brorby GP . 2018. The ongoing controversy surrounding the effects of short-term exposure to trichloroethene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, March 19–22, San Diego, CA.
Publication: Abstracts and Presentations
Pangburn HA, Jarvis JP, Covington TR , Ott DK, Gearhart JM. The impact of genetics on the pharmacokinetics of chemicals in a U.S. Air Force population. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
Gearhart JM, Pitts E, Covington TR , Grabinski CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Physiological simulation of thermal and chemical stressors in a United States Air Force population. Presentation at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
Covington TR , Ott DK, Gearhart JM, Pangburn HA. Development of a physiologically-based pharmacokinetic model for the virtual high-performance aircraft pilot. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
Publication: Abstracts and Presentations
Pecquet AM, Martinez JM, Vincent M , Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878, doi: 10.1002/jat.3594.
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Publication: Manuscripts
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415, doi: 10.1080/10408444.2018.1430121.
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Publication: Manuscripts
Choksi N , Daniel A, Lebrun S, Nguyen M, DeGeorge G, Willoughby JA, et al. Performance of the OptiSafe ocular irritation assay in a three-laboratory validation study. Poster presented at Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.
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Publication: Abstracts and Presentations
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer … Choksi N , et al. 2018. In vitro to in vivo extrapolation for high throughput prioritization and decision making. Toxicol In Vitro 47:213–227, DOI: 10.1016/j.tiv.2017.11.016
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Publication: Manuscripts
Buerger AN , Martyniuk CJ, Bisesi JH. Phthalate disruption of the gastrointestinal microbiome as a potential obesogenic mechanism: A multigenerational study using Danio rerio. Society of Toxicology Meeting, 2018.
Publication: Abstracts and Presentations
Buerger AN , Dillon DT, Martyniuk CJ, Bisesi JH. Host-microbiome alterations in fatty acid metabolism in Danio rerio following dietary phthalate exposure. Society of Environmental Toxicology and Chemistry North America Meeting, 2018.
Publication: Abstracts and Presentations
Zhou W, Pal AS, Hsu AY, Gurol T, Zhu X, Wirbisky-Hershberger SE , Freeman JL, Kasinski AL, Deng Q. 2018. MicroRNA-223 supresses the canonical NF-kB pathway basal keratinocytes to dampen neutrophilic inflammation. Cell Reprod 13:1810–1823.
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Publication: Manuscripts
Wikoff D , Urban JD , Harvey S , Haws LC . 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol 37(2):125-143; doi: 10.1177/1091581818754330.
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Publication: Manuscripts
Mihalchik AL, Rogers EN. 2018. Classes of compounds with GI tract toxicity. Chapter 13 in: Gad SC (ed), Toxicology of the Gastrointestinal Tract. CRC Press .
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Publication: Book Chapters
Doepker C , Franke K , Myers E, Goldberger JJ, Lieberman HR, O’Brien C, Peck J, Tenenbein M, Weaver C, Wikoff D . 2018. Key findings and implications of a recent systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Nutrients 10:1536, doi: 10.3390/nu10101536.
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Publication: Manuscripts
2017 (63 POSTS)
Wirbisky-Hershberger SE , Sanchez OF, Horzmann KA, Thanki D, Yuan C, Freeman JL. 2017. Atrazine exposure decreases the activity of DNMTs, global DNA methylation levels, and dnmt expression. Food Chem Toxico l 109:727–734.
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Publication: Manuscripts
Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C , Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; DOI: 10.1021/acs.chemrestox.7b00221.
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Publication: Manuscripts
McMillan DA , Kosemund K, Mahony C, Huber M, Bowtell P. Threshold of toxicological concern (TTC) for botanicals—Data analysis to substantiate and extend the TTC approach to botanicals. In: The Toxicologist: Suppl to Toxicol Sci 156(1), Abstract no. 1831, Society of Toxicology, 2017.
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Publication: Abstracts and Presentations
Antonia S, Claffey M, Balan G, Barreiro G, Barricklow J, Bohanon, M, Boscoe B, Cappon G , et al. 2017. Discovery and characterization of PF-06462894 (8), an alkyne-lacking metabotropic glutamate receptor 5 negative allosteric modulator profiled in both rat and non-human primates. J Medicinal Chem 60:7764–7780, DOI: 10.1021/acs.jmedchem.7b00604, online article .
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