Publication Topic

Katona MA, Long TF, Kirman CR, Gargas ML, Rish WR. Derivation of a cancer potency factor and dermal absorption factor for benzo(a)pyrene. Toxicologist 54, Abstract 873. Presented at Society of Toxicology 39th Annual Meeting, Philadelphia, PA, March 2000.

Jankowski-Hennig MA, Clegg MS, Daston GP, Rogers JM, Keen CL. 2000. Zinc-deficient rat embryos have increased caspase 3-like activity and apoptosis. Biochem Biophys Res Commun 271(1):250–256; doi: 10.1006/bbrc.2000.2608.

Lau C, Anderson ME, Crawford-Brown DJ, Kavlock RJ, Kimmel CA, Knudsen TB, Muneoka K, Rogers JM, Setzer RW, Smith G, Tyl R. 2000. Evaluation of biologically based dose-response modeling for developmental toxicity: A workshop report. Regul Toxicol Pharmacol 31(2):190–199; 10.1006/rtph.1999.1360.

Clewell HJ III, Gentry PR, Allen BC, Covington TR, Gearhart JM. 2000. Development of a physiologically-based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment. Environ Health Perspect 108(Suppl 2):283–305.

Gentry R, Clewell H, Covington T, Wilson J. Investigation of the impact of Benchmark and PBPK modeling on the derivation of MRLs. Poster presented at the Society of Toxicology Annual Meeting, Philadelphia, PA, March 2000.

Clewell HJ, Gentry PR, Gearhart JM, Born SL, Lehman-McKeeman LD, Covington TR. Development of a physiologically-based pharmacokinetic (PB-PK) model and human health risk assessment for coumarin.  Poster presented at the Society of Toxicology Annual Meeting, Philadelphia, PA, March 2000.

Choksi NY, Nix WB, Wyrick SD, Booth RG. 2000. A novel phenylaminotetralin (PAT) recognizes histamine H1 receptors and stimulates dopamine synthesis in vivo in rat brain. Brain Research 852(1):151–160; doi: 10.1016/s0006-8993(99)02228-3.

Choksi NY, Nix WB, Wyrick SD, Booth RG. Phenylaminotetralins activate histamine H1 receptors to stimulate dopamine synthesis in vivo in rat brain. Poster presented at the Receptor Chemistry Towards the Third Millennium – 12th Camerino-Noordwijkerhout Symposium, 1999.

Clewell HJ, Gearhart JM, Gentry PR, Covington TR, Van Landingham CB, Crump KS, and Shipp AM. 1999. Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics. Risk Anal 19:541–552.

Rish W, Kirman CR, Hays SM, Gargas ML, Andersen ME, Reitz RH, Guengerich FP, Green T, McConnell EE, Buckpit A, Voytek P, Dugard PH. 1999. Developing a physiologically based pharmacokinetic model to describe methylene chloride kinetics at the subcellular level. Toxicologist 48, Paper No. 671. Presented at Society of Toxicology 38th Annual Meeting, New Orleans, LA, March 1999.

Zucker RM, Hunter ES III, Rogers JM. 1999. Apoptosis and morphology in mouse embryos by confocal laser scanning microscopy. Methods 18(4):473–480; doi: 10.1006/meth.1999.0815.

Parvathy S, Choksi N, Fang Y, Sabo SL, Buxbaum JD. Characterization of multipartite complexes of APP. Poster presented at Society for Neuroscience Annual Meeting, 1999

Lilliehook C, Choksi NY, Hof P, Choi EK, Zaidi NF, Wasco W, et al. Characterization of the presenilin-binding protein calsenilin. Poster presented at Society for Neuroscience Annual Meeting, 1999

Fang Y, Choksi NY, Parvathy S, Yamin JJ, Wasco W, Buxbaum JD. Proteins interacting with the COOH-termini of the presenilins. Poster presented at Society for Neuroscience Annual Meeting, 1999.

Choksi NY, Mukherjeree P, Lindroth A, Xiang Z, Wasco W, Buxbaum JD, Pasinetti GM. Cyclooxygenase (COX)-2 expression is associated with presenilin-2 induced apoptosis. Poster presented at Society for Neuroscience Annual Meeting, 1999.

Gentry R, Clewell H, Gearhart J, Covington T, Andersen M. Development of a physiologically-based pharmacokinetic (PB-PK) model for isopropanol and acetone. Poster presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 1999.

Bogdanffy MS, Keller DA. 1999. Metabolism of xenobiotics by the respiratory tract. In: Gardener, DE (ed), Toxicology of the Lung, 3^rd ed., pp. 85–124. Taylor and Francis, Philadelphia, PA.

Kodavanti PR, Derr-Yellin EC, Mundy WR, Shafer TJ, Herr DW Barone S, Choksi, NY, MacPhail RC, Tilson HA. 1998. Repeated exposure of Aroclor 1254 causes brain region-specific changes in intracellular Ca2+ buffering and protein kinase C activity in the absence of changes in tyrosine hydroxylase. Toxicol Appl Pharmacol 153:186–198; doi: 10.1006/taap.1998.8533.

Gerhardt B, Kordas TJ, Thompson CM, Patel P, Vida TV. 1998. The vesicle transport protein, Vps33p, is an ATP binding protein that localizes to the cytosol in an energy dependent manner. J Biol Chem 273(25):15818–15829; doi: 10.1074/jbc.273.25.15818.

Thompson CM, Kawashima H, and Strobel HW. 1998. Isolation of partially purified P450 2D18 and characterization of activity towards the tricyclic antidepressants imipramine and desipramine. Arch Biochem Biophys 359(1):115–121; doi: 10.1006/abbi.1998.0892.