2025 (44 POSTS)
Jacobellis M , Garcia M, Bain L, Pearce J, Hunt K, Baldwin W. Disruption of energy homeostasis by chemical mixtures containing persistent pollutants in HepG2 and C2C12 cells. Abstract 4564, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: chemical safety assessment
Reynolds JI , Yelleti A, Johnson BP. Bridging data gaps in sonic hedgehog signaling: A novel microphysiological model approach. Abstract 3234, Society for Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: Adverse outcome pathways (AOPs) , modeling
Wikoff D . Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Topics: Food science , risk assessment
Wikoff D . Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Topics: Food science , risk assessment
2024 (67 POSTS)
Olaye A, Bean K, Velikanova R, Wolters S, Miller B, Jensen I, Pang F. Cost-effectiveness of atidarsagene autotemcel (ARSA-CEL) gene therapy for treating metachromatic leukodystrophy (MLD) in Ireland, Belgium, and the Netherlands as a part of the Beneluxa Initiative. Abstract EE693 , ISPOR Europe 2024, November 2024.
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Topics: Health Economics and Outcomes Research (HEOR) , Metachromatic leukodystrophy (MLD)
Haselkorn T, Hughes W, Lennox A, Schara-Schmidt U, Roca A, Miller B, Jensen I , et al. Real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in the United Kingdom (UK), Germany, and Spain. Abstract PCR257 , ISPOR EU 2024 (Top 5% Finalist).
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Topics: Health Economics and Outcomes Research (HEOR)
Schaefer H . Cadmium–Initiatives to reduce dietary exposure. Society for Risk Analysis Annual Meeting, Austin, TX, 2024.
Topics: cadmium , Exposure Assessment
Haselkorn T, Roca A, Miller B, Jensen I , Solomon F, Sanchez-de la Rosa R, Picart JM, Nascimento A. A real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in Spain. Presented at LXXVI Reunion Annual de la Sociedad Espanola de Nurologica, 19–23 November 2024.
Topics: Health Economics and Outcomes Research (HEOR)
Gauthier A, Bare J, Kramer M . Tools and tips for exposure assessment throughout the product development life cycle. Education session, PSX 2024, Annual Conference of the Product Stewardship Society, Denver, CO, October 2024.
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Topics: Exposure Assessment , Product Life Cycle , Product Stewardship
Kelsh M , Bylsma LC, Jiang X, Movva N , Sacks NC . To be an orphan disease or not to be: An evaluation of prevalence estimates for cancers near the orphan status threshold and implications for orphan drug planning. International Society for Pharmacoepidemiology, 40th Annual Meeting, Berlin, Germany, August 2024.
Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Suh M, Mittal L, Brorby G, Pastula S, Vincent M, Proctor D . Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
East A, Klaren W, Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S , et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: Epidemiology , mode of action
Covington TR , Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: modeling
Lea IA , Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: Systematic Review
Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: Health Economics and Outcomes Research (HEOR) , Systematic Review
Hampton LT, Kennedy SB , Barrick A, Wyler DB, Almroth BC, Coffin S, et al. The toxicity of microplastics explorer 2.0: Are we moving the needle forward on microplastics toxicity research? Abstract 7.03.T-05, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Topics: microplastics
Lane R, Gill S, Miller EL, Kennedy S , Shankar P, Williams T, et al. Rolling along: State of the science for tire related chemicals 6PPD and 6PPD-quinone. Abstract 4.22.P-Mo-115, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Topics: tire particles (TRWP)
Kennedy SB , Doyle D, Coffin S, Mair MM, Cowger W, Barrick A, et al. Trends in quality and risk assessment applicability of microplastic ecotoxicity studies. Abstract 7.03.P-Th-081, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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Topics: ecotoxicology , Environmental Science
Feifarek D, Kennedy S, Panko J. Mechanistic evaluation of 6PPD-quinone toxicity in fish. Abstract 4.22.B.T-03, Society of Environmental Toxicology and Chemistry 45th Annual Meeting, Fort Worth, TX, October 2024.
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