2016 (61 POSTS)

Cui Y, Li J, Weng L, Wirbisky SE, Freeman JL, Liu J, Liu Q, Yuan X, Irudayaraj J. 2016. Regulatory landscape and clinical implication of MBD3 in human malignant glioma. Oncotarget 7(49):81698–81714.

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Wirbisky SE, Weber GJ, Schlotman KE, Sepúlveda MS, Freeman JL. 2016. Embryonic atrazine exposure alters zebrafish and human miRNAs associated with angiogenesis, cancer, and neurodevelopment. Food Chem Toxicol 98:25–33.

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Thompson CM, Rager JE, Suh M, Ring CL, Proctor DM, Haws LC, Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57:706-716.

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De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M, Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid.  I. Chemical reduction and mitigation of mutagenicity. Toxicol Appl Pharmacol   306:113-119.

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Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD, Chen C, et al. 2016. Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects. Crit Rev Toxicol 46:900–910, DOI: 10.1080/10408444.2016.1224807, open access online.

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Borghoff SJ, Ring C, Banton M, Leavens TL. 2016. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes.  J Appl Toxicol, DOI 10.1002/jat.3412

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Wirbisky SE, Sepúlveda MS, Weber GJ, Jannasch AS, Horzmann KA, Freeman JL. 2016. Embryonic atrazine exposure elicits alterations in genes associated with neuroendocrine function in adult male zebrafish. Toxicol Sci 153:149–164.

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Bi P, Yue F, Karki A, Castro B, Wirbisky SE, Wang C, … Kuang, S. 2016. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med 213(10):2019–2037.

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Bi P, Yue F, Sato Y, Wirbisky S, Liu W, Shan T, Wen Y, Zhou D, Freeman J, Kuang S. 2016. Stage-specific effects of notch activation during skeletal myogenesis. Elife 5:e17355.

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Garabrant DH, Alexander DD, Miller PE, Fryzek JP, Boffetta P, Teta MJ, … Kelsh MA, et al. 2016. Mesothelioma among motor vehicle mechanics: An updated review and meta-analysis. Ann Occup Hyg 60(1):8–26.

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Hummel HD, Topp MS, Chang ET, Chia VM, Kelsh MA, Doemland ML, et al. 2016. Adverse events in adults with relapsed or refractory acute lymphoblastic leukemia (ALL): A literature review of recent clinical trials. J Leuk 4:1 http://dx.doi.org/10.4172/2329-6917.1000208

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Erichsen R, Kelsh MA, Oliner KS, Nielsen KB, Frøslev T, Lænkholm AV, et al. 2016. Prognostic impact of tumor MET expression among patients with stage IV gastric cancer: A Danish cohort study. Annals of Epidemiol 26(7): 500–503.

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Schmitt G, Ridings J, De Schaepdrijver L, van Doesum-Wolters C, Cappon GD, Hartmann A. 2016. Nonclinical safety considerations for the development of pediatric-first drugs: An industry view. Therapeut Innov Regul Sci 50(5):632–638, DOI:10.1177/2168479016642813, online article.

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Gökbuget N, Dombret H, Ribera JM, Fielding AK, Advani A, Bassan R, … Kelsh M, et al. 2016. International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia. Haematologica. 101(12):1524–1533. doi: 10.3324/haematol.2016.144311.

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Gökbuget N, Kelsh M, Chia V, Advani A, Bassan R, Dombret H, et al. 2016. Blinatumomab vs historical standard therapy of adult relapsed/refractory acute lymphoblastic leukemia. Blood Cancer J 6(9):e473.

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Mackay CE, Vivanco SN, Yeboah G, Vercellone J. 2016. Assessment of dermal hazard from acid burns with fire retardant garments in a full-size simulation of an engulfment flash fire. Burns 42(6):1350–1356.

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Strittholt CA, McMillan DA, He T, Baker RA, Barker ML. 2016. A randomized clinical study to assess ingestion of dentifrice by children. Regul Toxicol Pharmacol 75:66–71.

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Thompson CM, Suh M, Mittal L, Wikoff D, Welsh B, Proctor DM. 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80:60-70.

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Christine MC, Nikiforov AI, Rihner MO, Lambert EA, Greeley MA, Godsey J, Eapen AK, van de Ligt JLG. 2016. A 90-day oral (dietary) toxicity and mass balance study of corn starch fiber in Sprague Dawley Rats. Food Chem Toxicol 97:57.

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Christine MC, Garcia-Campayo V, Rihner MO, Nikiforov AI, Liska D, van de Ligt JLG. 2016. Evaluation of the gastrointestinal tolerability of corn starch fiber, a novel dietary fiber, in two independent randomized, double-blind, crossover studies in healthy men and women. Intl J Food Sci Nutr 67(7):844–856.

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