2016 (61 POSTS)
Cui Y, Li J, Weng L, Wirbisky SE , Freeman JL, Liu J, Liu Q, Yuan X, Irudayaraj J. 2016. Regulatory landscape and clinical implication of MBD3 in human malignant glioma. Oncotarget 7(49):81698–81714.
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Topics: Environmental Science
Wirbisky SE , Weber GJ, Schlotman KE, Sepúlveda MS, Freeman JL. 2016. Embryonic atrazine exposure alters zebrafish and human miRNAs associated with angiogenesis, cancer, and neurodevelopment. Food Chem Toxicol 98:25–33.
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Topics: Toxicology
Thompson CM , Rager JE, Suh M , Ring CL, Proctor DM , Haws LC , Fry RC, Harris MA . 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57:706-716.
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M , Proctor DM . 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid. I. Chemical reduction and mitigation of mutagenicity. Toxicol Appl Pharmaco l 306:113-119.
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD , Chen C, et al. 2016. Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects. Crit Rev Toxicol 46:900–910, DOI: 10.1080/10408444.2016.1224807, open access online .
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Topics: Toxicology
Borghoff SJ , Ring C, Banton M, Leavens TL. 2016. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol , DOI 10.1002/jat.3412
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Topics: Toxicology
Wirbisky SE , Sepúlveda MS, Weber GJ, Jannasch AS, Horzmann KA, Freeman JL. 2016. Embryonic atrazine exposure elicits alterations in genes associated with neuroendocrine function in adult male zebrafish. Toxicol Sci 153:149–164.
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Topics: Toxicology
Bi P, Yue F, Karki A, Castro B, Wirbisky SE , Wang C, … Kuang, S. 2016. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med 213(10):2019–2037.
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Topics: Toxicology
Bi P, Yue F, Sato Y, Wirbisky S , Liu W, Shan T, Wen Y, Zhou D, Freeman J, Kuang S. 2016. Stage-specific effects of notch activation during skeletal myogenesis. Elife 5:e17355.
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Topics: Toxicology
Garabrant DH, Alexander DD, Miller PE, Fryzek JP, Boffetta P, Teta MJ, … Kelsh MA , et al. 2016. Mesothelioma among motor vehicle mechanics: An updated review and meta-analysis. Ann Occup Hyg 60(1):8–26.
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Topics: Cancer , Epidemiology
Hummel HD, Topp MS, Chang ET, Chia VM, Kelsh MA , Doemland ML, et al. 2016. Adverse events in adults with relapsed or refractory acute lymphoblastic leukemia (ALL): A literature review of recent clinical trials. J Leuk 4:1 http://dx.doi.org/10.4172/2329-6917.1000208
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Topics: Cancer , Epidemiology
Erichsen R, Kelsh MA , Oliner KS, Nielsen KB, Frøslev T, Lænkholm AV, et al. 2016. Prognostic impact of tumor MET expression among patients with stage IV gastric cancer: A Danish cohort study. Annals of Epidemiol 26(7): 500–503.
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Topics: Cancer , Epidemiology
Schmitt G, Ridings J, De Schaepdrijver L, van Doesum-Wolters C, Cappon GD , Hartmann A. 2016. Nonclinical safety considerations for the development of pediatric-first drugs: An industry view. Therapeut Innov Regul Sci 50(5):632–638, DOI:10.1177/2168479016642813 , online article .
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Topics: Toxicology
Gökbuget N, Dombret H, Ribera JM, Fielding AK, Advani A, Bassan R, … Kelsh M , et al. 2016. International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia. Haematologica . 101(12):1524–1533. doi: 10.3324/haematol.2016.144311.
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Topics: Cancer
Gökbuget N, Kelsh M , Chia V, Advani A, Bassan R, Dombret H, et al. 2016. Blinatumomab vs historical standard therapy of adult relapsed/refractory acute lymphoblastic leukemia. Blood Cancer J 6(9):e473.
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Topics: Cancer
Mackay CE, Vivanco SN , Yeboah G, Vercellone J. 2016. Assessment of dermal hazard from acid burns with fire retardant garments in a full-size simulation of an engulfment flash fire. Burns 42(6):1350–1356.
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Topics: Toxicology
Strittholt CA, McMillan DA , He T, Baker RA, Barker ML. 2016. A randomized clinical study to assess ingestion of dentifrice by children. Regul Toxicol Pharmacol 75:66–71.
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Topics: Toxicology
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM . 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80:60-70.
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Topics: Systematic Review
Christine MC, Nikiforov AI, Rihner MO, Lambert EA, Greeley MA, Godsey J, Eapen AK, van de Ligt JLG . 2016. A 90-day oral (dietary) toxicity and mass balance study of corn starch fiber in Sprague Dawley Rats. Food Chem Toxicol 97:57.
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Topics: Food science
Christine MC, Garcia-Campayo V, Rihner MO, Nikiforov AI, Liska D, van de Ligt JLG . 2016. Evaluation of the gastrointestinal tolerability of corn starch fiber, a novel dietary fiber, in two independent randomized, double-blind, crossover studies in healthy men and women. Intl J Food Sci Nutr 67(7):844–856.
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