Publications

Kirman CR, Suh M, Proctor DM, Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325(15 June):9-17; doi: 10.1016/j.taap.2017.03.023.

Wikoff DS, Rager J, Harvey S, Haws L, Chappell G, Borghoff S. 2017. Framework for quantitative consideration of study quality and relevance in the systematic evaluation of mechanistic data per the Ten Key Characteristics of Carcinogens. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

Jackson MA, Yang L, Lea I, Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535; doi: 10.1002/em.22114.

Mease K, Kimzey A, Lansita J. 2017. Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design. Curr Opin Toxicol 4(June):1–15; doi: 10.1016/j.cotox.2017.03.005.

Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, et al. 2017. Multivariate models for prediction of human skin sensitization hazard. J Appl Toxicol 37:347–360; doi: 10.1002/jat.3366.

Lea IA, Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971; doi: 10.1093/nar/gkw1077.

Williams BH, Monnot AD, Patton A, Finley BL. Proposed chronic oral reference doses for thallium. Late-breaking poster presentation at Society of Toxicology 56^th Annual Meeting, Baltimore, MD, 2017.

Kovochich M, Fung ES, Donovan EP, Unice KM, Paustenbach DJ, Finley BL. Characterization of wear debris from metal-on-metal hip implants during normal wear versus edge loading conditions. Abstract #2143, Society of Toxicology 56^th Annual Meeting, Baltimore, MD, 2017.

Fung ES, Monnot AD, Tvermoes BE, Unice KM, Kovochich M, Galbraith DA, Finley BL, Paustenbach DJ. Characteristics of cobalt related cardiomyopathy in metal hip implant patients. Abstract #2142. Poster presentation at Society of Toxicology 56^th Annual Meeting, Baltimore, MD, 2017.

Finley BL, Scott PK, Burns AM, Marsh GM. Does PCB exposure cause non-Hodgkins lymphoma? A weight of evidence evaluation. Abstract 3240, Society of Toxicology 56^th Annual Meeting, Baltimore, MD, 2017.

Finley BL, Glynn ME, Cyrs WD, Beckett EW, Gaffney SH, Monnot AD, Abelmann A, Parker A, Maier MA. Derivation of an occupational exposure limit for diacetyl: A preliminary analysis. Late-breaking poster presentation at Society of Toxicology 56^th Annual Meeting, Baltimore, MD, 2017.

Finley BL, Donovan ED, Kovochich M, Paustenbach DJ, Urban AM. Perineal use of cosmetic talc as a risk factor for ovarian cancer: A weight-of-evidence evaluation. Abstract #1288. Poster presentation at Society of Toxicology 56^th Annual Meeting, Baltimore, MD, 2017.

Benson SM, Marsh GM, Finley BL. Cosmetic talc as a risk factor for mesothelioma: A weight-of-evidence evaluation. Abstract #1290. Poster presentation at Society of Toxicology 56^th Annual Meeting, Baltimore, MD, 2017.

Doepker D, Tyndall K, Lane R, Wikoff D, Thompson C, Harvey S, Schmitt D. 2017. A proposed ADI for nitrate. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Borghoff SJ, Ring C, Banton MI, Leavens TL. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to 2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Thompson C, Rager J, Suh M, Proctor D, Haws L, Harris M. Mechanistic support for nonlinear risk assessment of rat oral cavity tumors induced by exposure to Cr(VI) in drinking water. Poster presented at 56th Society of Toxicology Annual Meeting. March 15, Baltimore, MD, March 2017.

Chappell G, Welsh B, Harvey S, Harris M, Wikoff D. Validation and application of a text mining tool in the identification and categorization of mechanistic data: A case study in improving problem formulation of carcinogenicity assessments. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Proctor DM, Suh M, Dunsmore D, Verwiel A, Casteel S. Bioaccessibility and relative oral bioavailability of cobalt and nickel from metal alloys in soil and dust. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Kirman CR, Proctor D, Suh M, Haws L, Harris M, Thompson C, Hays S. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Rager JE, Thompson CM, Ring C, Fry RC, Harris MA. Integration of transcriptomics and high-throughput screening predictions with robust in vivo data to inform hexavalent chromium mode of action. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.