Publications

Suzuki T, Campos B, Fassbender C, Grassi G, Hodges J, Kennedy S, et al. Advancing animal-free environmental safety assessments: Development and application of an integrated next generation risk assessment (NGRA) framework. Presentation 5.09.T-02, SETAC North America 47^th Annual Meeting, Montreal, Canada, November 2026.

Rish W, Kennedy S. Integrating ecological and human health risk in cumulative impact assessment. Platform presentation 5.09.T-01, SETAC North America 47^th Annual Meeting, Montreal, Canada, November 2026.

Covell L. Evaluating post-derailment PAH concentration trends in East Palestine sediment using linear mixed-effects modelling. Poster 5.16.P-We295, SETAC North America 47^th Annual Meeting, Montreal, Canada, November 2026.

Fender CL, Bare J, Kennedy S, Panko J, Proctor D. Characterization and considerations of atmospheric deposition as an aquatic exposure pathway. Poster 4.18.P-Tu276, SETAC North America 47th Annual Meeting, Montreal, Canada, November 2026.

Bare JL, Truong L, Simonich M, Rothenberg SE. Investigation of dichlorooctylisothiazolinone (DCOI) in surface water and neurobehavioral effects in zebrafish (Danio rerio). Poster M-11, Superfund Research Program (SRP) Annual Meeting, Portland, OR, October 2026.

Hooda N, Suh M, Bylsma LC, Kelsh M. A systematic literature review of the association between dose reduction of cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors and survival in patients with HR-positive breast cancer (BC). Poster 1882eP, European Society for Medical Oncology (ESMO) Congress 2026, Madrid, Spain, October 23-27, 2026.

Nagyal M, Kopanska K, Rovida C, Antignac E, Barton-Maclaren T, Congreave I, Escher SE,…, Patlewicz G, et al. From thresholds to odds: AI-enhanced applications of the threshold of toxicological concern (TTC) in modern risk assessment. Oral Session 3, Poster OR-12, American Society for Cellular and Computational Toxicology (ASCCT) 15^th Annual Meeting, Durham, NC, October 28, 2026.

Mihalchik AL. TTC in context: Comparing the pharmaceutical TTC with other regulatory sectors. Oral Session 3, Poster OR-09, American Society for Cellular and Computational Toxicology (ASCCT) 15^th Annual Meeting, Durham, NC, October 28, 2026.

Covington T, Borghoff SJ, Sims JL, Kamel A, Markey K, Wetmore BA, Lynn SG. Use of an in silico mass balance model to predict chemical suitability for screening chemicals in a high-throughput assay platform for potential endocrine activity. Poster 3, Poster Session II, American Society for Cellular and Computational Toxicology (ASCCT) 15^th Annual Meeting, Durham, NC, October 28, 2026

Patlewicz G, Mihalchik AL. Refinement of the threshold of toxicological concern (TTC): A computational framework for cross-scheme comparison of TTC values. Poster Session 1, Poster 24, American Society for Cellular and Computational Toxicology (ASCCT) 15^th Annual Meeting, Durham, NC, October 27, 2026.

Bylsma L, Kelsh M, Jiang X, Mitchell M, Movva N, Sacks NC. To be or not to be a rare disease: An evaluation of prevalence estimates for cancers near the orphan status threshold. Poster O-008, National Organization for Rare Disorders (NORD) Rare Diseases and Orphan Products Breakthrough Summit, Washington, DC, October 25-27, 2026.

Schaefer HR, Frankenfeld CL, Wikoff D. 2026. Low- and no-calorie sweeteners lack shared target organs or modes of action required for cumulative risk assessment. Food Chem Toxicol 218(Dec):116424; doi: 10.1016/j.fct.2026.116424. PMID: 42829191. 

Mihalchik AL, Roberts A, LaCombe J, Lloyd M, Doepker C, Eapen A. 2026. Evaluation of the safety and potential genotoxicity of a high-purity mogroside ingredient containing siamenoside I produced from a modified strain of Yarrowia lipolytica. Toxicol Rep 17(Dec):102297; doi: 10.1016/j.toxrep.2026.102297. PMID: 42388455.

East A, Klaren W, Wikoff D, Patlewicz G. Identifying potential co-exposures with food additives using data mining and machine learning approaches across EPA’s Consumer Product Database (CPDat). Abstract M-36, Poster Session, International Society of Exposure Science (ISES) 2026 Annual Meeting, Vancouver, BC, Canada, October 5, 2026.

Marden E, Jacobs KM, Doepker C. Science, safety, and chemical risk. General Session 6, Consumer Healthcare Products Association (CHPA) Regulatory and Scientific Affairs Conference (RSQ), Rockville, MD, September 30, 2026.

Patlewicz GY, Mihalchik AL. 2026. Revisiting the Threshold of Toxicological Concern: A computational framework for structural classification, cross-scheme comparison and opportunities for refinement. Comput Toxicol 39(Sept):100443; doi: 10.1016/j.comtox.2026.100443.

Price C, Rethlefsen ML. 2026. Librarians and information specialists: Partners in evidence-based toxicology and other disciplines. 4(1):2728359; doi: 10.1080/2833373X.2026.2728359.

Wikoff D, Wages PA. Where science meets reality: The role of real-world evidence (RWE) in modern personal care safety assessment. 2026 Personal Care Products Council (PCPC) Science Symposium & Expo, Arlington, VA, September 17, 2026.

Kennedy S. Next-generation environmental risk assessment for cosmetics ingredients—Framework and case study. 2026 Personal Care Products Council (PCPC) Science Symposium & Expo, Arlington, VA, September 16, 2026.

Doepker C, Kingston R, Wilson J. Global developments in botanical safety. American Herbal Products Association (AHPA) Botanical Congress 2026, Portland, OR, September 15, 2026.