2020
Wikoff DS , Urban JD , Ring C , Britt J , Fitch S , Haws LC . 2020. Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression. Toxicol Sci (Advance Access ).
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Publication: Manuscripts
/ Topics: Toxicology
Levin-Sparenberg E, Bylsma LC , Lowe K, Sangare L, Fryzek JP , Alexander DD. 2020. A systematic literature review and meta-analysis describing the prevalence of KRAS, NRAS, and BRAF gene mutations in metastatic colorectal cancer. Gastroenterol Res 13(5):184–198. doi: 10.14740/gr1167.
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Publication: Manuscripts
/ Topics: Epidemiology
Bhat VS , Cohen SM, Gordon EB, Wood CE, Cullen JM, Harris MA , Proctor DM , Thompson CM . 2020. An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: A case study with hexavalent chromium, captan, and folpet. Crit Rev Toxicol 50(8) (open access) .
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Publication: Manuscripts
/ Topics: Toxicology
Minor G, Yamamoto S, Cekola P, Cohen SS , Huhman MB, Araujo Torres K. 2020. Meeting nutritional needs of the enterally-fed child with neurological impairment. J Clin Nutr Dietet 6(4):3.
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Publication: Manuscripts
/ Topics: Epidemiology
Wikoff D , Lewis JR, Erraguntla N, Franzen A , Foreman J. 2020. Facilitation of risk assessment with evidence-based methods — A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertainty. Regul Toxicol Pharmacol (in press), journal pre-press online.
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Publication: Manuscripts
/ Topics: Systematic Review
Cohen SS , Roger VL, Weston SA, Jiang R, Movva N , Yusuf AA, Chamberlain AM. 2020. Evaluation of claims-based computable phenotypes to identify heart failure patients with preserved ejection fraction. Pharmacol Res Persp (open access).
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Publication: Manuscripts
/ Topics: Epidemiology
Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D , Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118:104788.
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Publication: Manuscripts
/ Topics: Toxicology
Fryzek J , Bylsma L , Mease K , Movva N , Welsh BT , Wood M . 2020. Critical insights into nonclinical toxicology and real-world evidence essential for a successful rare disease product launch. EpidStrategies, Inc., white paper.
White Paper
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Publication: White paper
/ Topics: Toxicology
Mahony CA, Bowtell P, Huber M, Kosemund K, Pfuhler S, Zhu T, Barlow S, McMillan DA . 2020. Threshold of toxicological concern (TTC) for botanicals — Concentration data analysis of potentially genotoxic constituents to substantiate and extend the TTC approach to botanicals. Food Chem Toxicol 138:111182.
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Publication: Manuscripts
/ Topics: Toxicology
Gage SM, Reichert H. 2020. Determining the incidence of needle-related complications in hemodialysis access: We need a better system. J Vascular Access .
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Publication: Manuscripts
/ Topics: Epidemiology
Elbeddini A, Hooda N, Yang L. 2020. Role of Canadian pharmacists in managing drug shortage concerns amid the COVID-19 pandemic. Canadian Pharmacists J , doi: 10.1177/1715163520929387.
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Publication: Manuscripts
/ Topics: Epidemiology
Boice JD, Cohen SS , Mumma MT, Chen H, Golden AP, Beck HL, Till JE. 2020. Mortality among US military participants at eight aboveground nuclear weapons test series. Int J Radiat Biol , doi: 10.1080/09553002.2020.1787543.
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Publication: Manuscripts
/ Topics: Epidemiology
Ard, JD, Lewis KH, Cohen SS , Rothberg A, Coburn SL, Loper J. Matarese L, Pories WJ, Periman S. 2020. Differences in treatment response to a total diet replacement intervention vs. a food-based intervention: A secondary analysis of the OPTIWIN trial. Obesity Sci Pract , doi: 10.1002/osp4.444.
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Publication: Manuscripts
/ Topics: Epidemiology
Suh M , Jiang X, Movva N, Fryzek J, Bylsma L, Rizzo C, Nelson CB. Hospitalizations and emergency department visits for respiratory syncytial virus among infants aged <1 year in the United States: An analysis of nationwide inpatient and emergency room data. Presentation to IDWeek virtual conference on infectious disease, October 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Fergie J, Gonzales T, Suh M , Jiang X , Fryzek, J , Howard A, Bloomfield A. 2020. Respiratory syncytial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH) among children aged ≤24 months at the start of RSV season with bronchopulmonary dysplasia/chronic lung disease of prematurity (BPD/CLDP) before and after the 2014 American Academy of Pediatrics (AAP) policy. Presentation to IDWeek virtual conference on infectious disease, October 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Fergie J, Gonzales T, Suh M , Jiang X , Fryzek, J , Howard A, Bloomfield A. 2020. Medically attended respiratory syncytial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH) among children aged ≤24 months at RSV season start with higher-risk congenital heart disease (CHD) before and after the 2014 American Academy of Pediatrics (AAP) policy. Presentation to IDWeek virtual conference on infectious disease, October 2020.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Loper J, Lewis KH, Rothberg A, Auriemma A, Coburn SL, Cohen SS , Matarese L, Pories WJ, Jiang X , Periman S, Ard JD. Weight change in participants completing meal replacement program is related to level of engagement. Obesity Week virtual conference, 2020.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Cohen S , Reichert H, Kansal AR, Chung KC. Improved efficiency of cancer screening with multi-cancer early detection test. ISPOR (International Society for Pharmacoeconomics and Outcomes Research, Inc.) virtual conference, May 2020.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Chamberlain AM, Reading SR, Dluzniewski PJ, Killian JM, Weston SA, Bjorkenstam E, Cohen SS . Identification and characterization of the high cardiovascular risk patient with multiple events. CSANZ (Cardiac Society of Australia and New Zealand) virtual conference, Dec 2020.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Rankin DA, Haddadin Z, Lipworth L, Fryzek J , Suh M , Shepard DS, McHenry R, Varjabedian R, Fernandez KN, Rizzo C, Nelson CB, Halasa NB. Comparison of clinical presentations and burden of respiratory syncytial virus in infants across three distinct healthcare settings. IDWeek virtual conference on infectious disease, October 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Haddadin Z, Rankin DA, Lipworth L, Fryzek J , Suh M , Shepard DS, McHenry R, Varjabedian R, Fernandez KN, Rizzo C, Nelson CB, Halasa NB. Distribution of respiratory viral pathogens in infants across different clinical settings from December 2019 to April 2020. IDWeek virtual conference on infectious disease, October 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Haddadin Z, Rankin DA, Lipworth L, Fryzek J , Suh M , Shepard DS, McHenry R, Varjabedian R, Fernandez KN, Rizzo C, Nelson CB, Halasa NB. Clinical characteristics of common respiratory viruses detected in infants across different clinical settings. IDWeek virtual conference on infectious disease, October 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Shepard DS, Perloff J, Jiang S , Suh M , Fryzek J , Bowser D, Rizzo C, Nelson CB. Impacts of age and season on rates of hospitalization for respiratory syncytial virus (RSV) in infants in the United States and their use of mechanical ventilation and charges. IDWeek virtual conference on infectious disease, October 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Eskes C, Corsini E, Hanley V, Karadjova I, Kopp-Schneider A, Suh M , Alves P, Clewell R, Cotgreave I, Navas J, Piersma A, Westmoreland C. 2020. ESAC opinion on the scientific validity of the bioelution test method. In: Viegas Barroso J (ed), EUR 30281 EN . Publications Office of the European Union, Luxembourg, ISBN 978-92-76-20004-8 (online), doi:10.2760/023005 (online), JRC121143.
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Publication: Manuscripts
/ Topics: Epidemiology
Chorley BN, Carswell GK, Nelson G, Bhat VS , Wood CE. 2020. Early microRNA indicators of PPARα pathway activation in the liver. Toxicol Rep 7:805–815.
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Publication: Manuscripts
/ Topics: Toxicology
Christiansen CF, Farkas DK, Fryzek JP , Romagnani P, Nørgaard M, Rothman KJ, Toft Sørensen H. Risk and prognosis of cancer after acute kidney injury. Presentation to the 36th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, Berlin, Germany, August 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Vago EK, Nicholson G, Horvath-Puho E, Fryzek JP , Su J. Healthcare resource utilization among cold agglutinin disease (CAD) patients in Denmark. Presentation to ISPOR Europe 2020 virtual conference, November 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Henderson RG, Franzen A, Franke K, Payne L , Schmitt D, Wikoff D. Creating a literature database for cannabidiol (CBD): Systematic evidence mapping. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Krehnbrink M, Patel K, Byerley J, Tarantino H, Peyser B, Payne L , Foley K, Latessa R. 2020. Physician preceptor satisfaction across curricula: Comparing longitudinal integrated clerkships and traditional block rotations. Teach Learn Med 32(2):176–183. doi: 10.1080/10401334.2019.1687304.
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Publication: Manuscripts
Thompson CM , Donahue DA, Hobbs C, Costecalde Y, Franzen A , Suh M , Proctor DM , Harris MA . 2020. Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice. Regul Toxicol Pharmacol 116, open access.
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Publication: Manuscripts
/ Topics: Environmental Science , Toxicology
Fergie J, Suh M, Jiang X, Fryzek JP , Gonzales T. 2020. Respiratory syncytial virus and all-cause bronchiolitis hospitalizations among preterm infants using the Pediatric Health Information System (PHIS). J Infectious Dis : open-access accepted ms. ahead of print.
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Publication: Manuscripts
/ Topics: Epidemiology
Dronin-Fenton D, Dalvi T, Movva N , Pedersen I, Hansen H, Fryzek J , Mellemgaard A, Rasmussen T, Klein A, Hamilton-Dutoit S, Nørgaard M. PD-L1 expression and survival in stage III unresectable non-small cell lung cancer patients in Denmark. Accepted for presentation to a virtual meeting (due to COVID-19) of the European Society for Medical Oncology (ESMO), abstract #2865, August 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology
Elbeddini A, Hooda N , Gazarin M, Webster P, McMillan J. 2020. Irinotecan-associated dysarthria in patients with pancreatic cancer: A single site experience. Am J Case Rep , doi: 10.12659/AJCR.924058.
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Publication: Manuscripts
/ Topics: Epidemiology , Toxicology
Whaley P, Aiassa E, Beausoleil C, Beronius A, Bilotta, G, Boobis A, de Vries R, Hanberg A, Hoffman S, Hunt N, Kwiatkowski CF, Lam J, Lipworth S, Martin O, Randall, N, Rhomberg L, Rooney AA, Holger J, Schünemann HJ, Wikoff D , Wolffe T, Halsall C. 2020. Recommendations for the conduct of systematic reviews in toxicology and environmental health research (COSTER). Environ Int 143:105926.
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Publication: Manuscripts
/ Topics: Systematic Review
Chesney A , Welsh B , Kimzey A , Lansita J. The process and challenges of deriving exposure-based limits for toxicological risk assessment for components and impurities present in cell therapy products with case studies. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Bell S, Abedini J, Ceger P, Chang X, Cook B, Karmaus AL, Lea I , Mansouri K, Phillips J, McAfee E, Rai R, Rooney J, Sprankle C, Tandon A, Allen D, Casey W, Kleinstreuer N. 2020. An integrated chemical environment with tools for chemical safety testing. Toxicol in Vitro 67:104916.
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Publication: Manuscripts
/ Topics: Toxicology
Chappell GA , Thompson CM , Wolf JC, Cullen JM, Klaunig JE, Haws LC . 2020. Assessment of the mode of action underlying the effects of GenX in mouse liver and implications for assessing human health risks. Toxicol Pathol 48(3):494–508, doi: 10.1177/0192623320905803. PMID: 32138627.
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Publication: Manuscripts
/ Topics: Toxicology
Urban JD , Wikoff DS , Chappell GA , Harris C, Haws LC . 2020. Systematic evaluation of mechanistic data in assessing in utero exposures to trichloroethylene and development of congenital heart defects. Toxicology 436:152427, doi: 10.1016/j.tox.2020.152427. PMID: 32145346.
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Publication: Manuscripts
/ Topics: Toxicology
Keele GR, Quach BC, Israel JW, Chappell GA , Lewis L, Safi A, et al. 2020. Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation. PLoS Genet 16(1):e1008537, doi: 10.1371/journal.pgen.1008537.
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Publication: Manuscripts
/ Topics: Toxicology
Mavunda K, Jiang X , Ambrose CS. 2020. Prevalence and clinical characteristics of perinatal chronic lung disease by infant gestational age. J Neonatal-Perinatal Med , DOI: 10.3233/NPM-200412.
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Publication: Manuscripts
/ Topics: Epidemiology
Heintz, MM, McRee, R, Kumar, R, Baldwin, WS. 2020. Gender differences in diet-induced steatotic disease in Cyp2b-null mice. PLoS ONE 15(3):e0229896.
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Publication: Manuscripts
/ Topics: Toxicology
Saldanha G, Ording AG, Bylsma LC , Darvalics B, Solis D, Tang JY, Sorensen HT, Fryzek J . 2020. High-frequency basal cell carcinoma in Danish patients: Prevalence and consistency. J Eur Acad Dermatol Venereol [Early View], http://dx.doi.org/10.1111/jdv.16512 .
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Publication: Manuscripts
/ Topics: Epidemiology
Chappell GA , Wikoff DS , Doepker CL , Borghoff SJ . 2020. Lack of potential carcinogenicity for acesulfame potassium — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 141:111375 [open access ].
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Publication: Manuscripts
/ Topics: Systematic Review
Chappell GA , Britt JK , Borghoff, SJ . 2020. Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes. Food Chem Toxicol 140:111310 [open access] .
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Publication: Manuscripts
/ Topics: Systematic Review
Su J, Bylsma LC , Jiang X , Morales Arias J, Jain N, Nordyke RJ. 2020. Healthcare resource utilization among commercially insured patients with cold agglutinin disease in the United States. J Med Econ , DOI: 10.1080/13696998.2020.1764006.
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Publication: Manuscripts
/ Topics: Epidemiology
Bylsma LC , Dean R, Lowe K, Sangare L, Alexander D, Fryzek J . The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis of patient and study characteristics. Poster for Society of Toxicology , virtual annual meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Epidemiology , Systematic Review
Saldanha G, Ording AG, Bylsma LC , Darvalics B, Solis D, Tang JY, Sorensen HT, Fryzek J . 2020. High frequency basal cell carcinoma (BCC) in Danish patients: Prevalence and consistency. J Eur Acad Dermatol Venereol Apr 20 doi: 10.1111/jdv.16512 (Epub ahead of print).
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Publication: Manuscripts
/ Topics: Epidemiology
Haws L (session co-chair). Introduction to “Use of New Approach Methods in Risk Characterization of PFAS: Challenges and Opportunities.” 44th Annual Winter Meeting, the Toxicology Forum, Tysons, VA, Jan 2020 (see: https://dialogue.toxforum.org/d/do/894 ).
Publication: Abstracts and Presentations
/ Topics: Toxicology
Vater S . Update: New data requirements for sunscreen over the counter additives—Challenges and opportunities. Presentation at 44th Annual Winter Meeting, the Toxicology Forum, Tysons, VA, Jan 2020 (see: https://dialogue.toxforum.org/d/do/913 ).
Publication: Abstracts and Presentations
/ Topics: Toxicology
Antonijevic T , Shah I. Predicting subchronic and chronic animal toxicity from in vitro high content imaging data using PBTK and machine learning. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Franzen A , Borghoff SJ . An adverse outcome pathway for renal tumors in male rats through chemical induction of aa2u-globuline (a2u) nephropathy (a2u-N). Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Bylsma LC , Dean R, Lowe K, Sangare L, Alexander D, Fryzek J . The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis of patient and study characteristics. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
View Abstract
Publication: Abstracts and Presentations
/ Topics: Systematic Review
Henderson RG , Franzen A , Franke K , Payne L , Schmitt D , Wikoff D . Creating a literature database for cannabidiol (CBD): Systematic evidence mapping. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
View Abstract
Publication: Abstracts and Presentations
/ Topics: Epidemiology , Systematic Review
Ring C, Fitch S , Haws L , Harris M , Wikoff D . Quantitative integration of dose-response data for relative potency estimates of dioxin-like chemicals. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Suh M , Verwiel A , Proctor D . Oral and inhalation bioaccessibility of cobalt and nickel in metal alloys: A critical consideration for site-specific human health risk assessments and read across. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Thompson CM , Ring C, Pham L, Chappell GA , Haws LC . Assessment of the relevance of toxicological findings in the development of an oral reference dose for GenX. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Wikoff D , Franzen A , Chappell G , Harris M , Thompson C . Systematic characterization of hexavalent chromium and potential female reproductive outcomes: Application of US EPA critical appraisal tools and stepwise inclusion of mechanistic data. Poster for Society of Toxicology , Virtual Annual Meeting, 2020.
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Publication: Abstracts and Presentations
/ Topics: Hexavalent Chromium , Toxicology
Bhat V , Zang Y. Globally harmonized guidance for dose-response analysis and derivation of health-based guidance values for chemicals in food. Part I (Zang)—What’s new; Part II (Bhat)—Intuitive Demonstrations. Society of Toxicology virtual meeting (59th Annual Meeting), April 21, 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Pham LL, Borghoff SJ , Thompson CM . 2020. Comparison of threshold of toxicological concern (TTC) values to oral reference dose (RfD) values. Regul Toxicol Pharmacol 113:104651 [open access ].
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Publication: Manuscripts
/ Topics: Toxicology
Broome CM, Cunningham JM, Mullins M, Jiang X , Bylsma LC , Fryzek JP , Rosenthal A. 2020. Increased risk of thrombotic events in cold agglutinin disease: A 10-year retrospective analysis. Res Prac Thrombosis Haemostasis, open access .
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Publication: Manuscripts
/ Topics: Epidemiology
Bell S, Mansouri K, Phillips J, Chang X, Abedini J, Karmaus AL, Lea I , Rai R, Allen DG, Casey W, Kleinstreuer NC. NCEATM computational tools and resources supporting alternative test method development and evaluation. Presented at the 59th Annual Meeting of Society of Toxicology, Anaheim CA, March 2020. Abstract #2976-P607.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Heintz MM , Olack EM, Baldwin WS. Human CYP2B6 is an anti-obesity enzyme that produces active α-linolenic acid metabolites. Society of Toxicology meeting, Anaheim, CA, March 2020.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Heintz MM , McRee R, Kumar R, Baldwin WS. Gender differences in diet-induced nonalcoholic steatohepatitis (NASH) in Cyp2b-null mice. Society of Toxicology meeting, Anaheim, CA, March 2020.
View Abstract
Publication: Abstracts and Presentations
/ Topics: Toxicology
Wikoff DS , Bennett DC, Brorby GP , Franke KS . 2020. Evaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth. Food Addit Contam Part A ; DOI: 10.1080/19440049.2020.1727963.
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Publication: Manuscripts
/ Topics: Toxicology
Yamamoto S, Allen K, Jones KR, Cohen SS , Reyes K, Huhmann MB. 2020. Meeting calorie and protein needs in the critical care unit: A prospective observational pilot study. Nutr Metab Insights 13:1–7; doi: 10.1177/1178638820905992.
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Publication: Manuscripts
/ Topics: Epidemiology
ApSimon M, Johnston C, Winder B, Cohen SS , Hopkins B. 2020. Narrowing the protein deficit gap in critically ill patients using a very high-protein enteral formula. Nutr Clin Practice 0:1–7, DOI: 10.1002/ncp.10472.
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Publication: Manuscripts
/ Topics: Epidemiology
Nelson CB, Broor S, Fryzek J , Wairagkar NS. 2020. Respiratory syncytial virus. Chapter 59 in: Vashishtha VM (Ed), IAP Textbook of Vaccines, Second Edition. Indian Academy of Pediatrics.
Publication: Book Chapters
/ Topics: Epidemiology
2019
Bylsma LC , Gillezeau C, Garawin TA, Kelsh MA, Fryzek JP , Sangaré L, Lowe KA. 2019. Prevalence of RAS and BRAF mutations in metastatic colorectal cancer patients by tumor sidedness: A systematic review and meta-analysis. Cancer Med Dec 19, doi: 10.1002/cam4.2747.
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Publication: Manuscripts
/ Topics: Epidemiology
Benson SM, Maskrey JR, Nembhard MD, Unice KM, Shirley MA, Panko JM . 2019. Evaluation of personal exposure to surgical smoke generated from electrocautery instruments: A pilot study. Ann Work Expos Health wxz070; open access.
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Publication: Manuscripts
/ Topics: Toxicology
Wikoff DS , Chappell GA , Fitch S , Doepker CL , Borghoff SJ . 2019. Lack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135:110866.
View Abstract
Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Adams R, Brickel J, Bhat VS . 2019. Chemical-specific maximum allowable levels for pesticide residues in dietary supplements. Food Chem Toxicol 123:511-519.
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Publication: Manuscripts
/ Topics: Toxicology
Gollapudi P, Bhat VS , Eastmond D. 2019. Concentration-response studies of the chromosome-damaging effects of topoisomerase II inhibitors determined in vitro using human TK6 cells. Mut Res Gen Toxicol Environ Mutagen 841:49-56.
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Publication: Manuscripts
/ Topics: Toxicology
Czerkies LM, Finn KL, Kineman BD, Reichert HA , Cohen SS , Carvalho RS. 2019. Use of a partially hydrolyzed 100% whey-based infant formula with Lacrobacillus reuteri in infants with caregiver-perceived intolerance. J Pedat Health Nutr, Open Access .
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Publication: Manuscripts
Marschke S, Rish W , Mauro J. 2019. Radiation exposures from the beneficial use of alumina production residue. J AWWA online .
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Publication: Manuscripts
/ Topics: Environmental Science
Krelder ML, Unice KM, Panko JM . 2019. Human health risk assessment of tire and road wear particles (TRWP) in air. Hum Ecol Risk Assess , open access.
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Publication: Manuscripts
/ Topics: Toxicology
Chappell GA , Borghoff SJ , Pham L, Doepker CL , Wikoff DS . 2019. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135:110898.
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Publication: Manuscripts
/ Topics: Systematic Review , Toxicology
Bylsma LC , Ording AG, Rosenthal A, Öztürk B, Fryzek JP , Arias JM, Röth A, Berentsen S. 2019. Occurrence, thromboembolic risk, and mortality in Danish patients with cold agglutinin disease. Blood Advances 3(20):2980–2985.
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Publication: Manuscripts
/ Topics: Epidemiology
Thompson C , Chappell G, Cullen J, Wolf JC, Haws L. Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic Meeting, Durham, NC, August 2019.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Chappell GA, Thompson CM , Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Thompson CM . The useful chemistry of perfluorinated compounds: Managing safety. The sticky subject of non-stick: Regulatory science challenges of per- and poly-fluorinated compounds (PFAS). Texas A&M University Interdisciplinary Faculty of Toxicology Training Program, 2019 Annual Regulatory Science Symposium. August 20, 2019.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Andersen ME, Gentry PR, Swenberg JA, Mundt KA, White KW, Thompson C , Bus J, Sherman JH, Greim H, Bolt H, Marsh GM, Checkoway H, Coggon D, Clewell HJ. 2019. Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop. Regul Toxicol Pharmacol 106:210–223.
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Publication: Manuscripts
/ Topics: Toxicology
Clewell RA, Thompson CM , Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301:112–127.
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Publication: Manuscripts
/ Topics: Toxicology
Chappell G , Rager J, Wolf J, Babic M, Leblanc, Ring C, Harris MA , Thompson CM. 2019. Comparison of gene expression responses in the small intestine of mice following exposure to three carcinogens using the S1500+ gene set informs a potential common adverse outcome pathway. Toxicol Pathol 47(7):851-864.
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