2021

Röth A, Fryzek J, Jiang X, Reichert H, Patel P, Su J, Morales Arias J, Broome CM. 2021. Complement-mediated hemolysis persists year round in patients with cold agglutinin disease. Transfusion [online] 1–9; doi: 10.1111/trf.16745.

View Abstract

Franke K, Payne L, Franzen A, Wikoff D, Henderson R. 2021. Cannabidiol literature scoping review protocol. Center for Open Science, OSFHOME (May 20).

View Abstract

Wikoff D, Edwards S, Angrish M, Baumgartner, Bever R, Borghoff S, Chappell G, Chew R, Fitch S, Hench G, Hamernik K, Henderson D, Kirk A, Lea I, Mandel M, Payne L, Shapiro S, Urban J, Williams D, Markey K. Application of systematic methods to characterize thyroid adverse outcome pathways (AOPs). Presented at 10th annual meeting of American Society for Cellular and Computational Toxicology (virtual), October 2021.

View Abstract

Blanchette AD, Burnett SD, Grimm FA, Rusyn I, Chiu WA. 2020. A Bayesian method for population-wide cardiotoxicity hazard and risk characterization using an in vitro human model. Toxicol Sci 178(2):391–403, doi: 10.1093/toxsci/kfaa151. PMID: 33078833.

View Abstract

Stan SV, Grathwohl D, O’Neill LM, Saavedra JM, Butte NF, Cohen SS. 2021. Estimated energy requirements of infants and young children up to 24 months of age. Curr Dev Nutr 5(11):1–9.

View Abstract

Racz L, Rish W. 2021. Exposure monitoring toward environmental justice. Integ Environ Assess Manag 00:1–5; available online.

View Abstract

Black MB, Andersen ME, Pendse SN, Borghoff SJ, Streicker M, McMullen PD. 2021. RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days. Data in Brief 38:107420. doi: 10.1016/j.dib.2021.107420. PMID: 34660856; PMCID: PMC8502903.

View Abstract

Palermo CM, Foreman JE, Wikoff DS, Lea I. 2021. Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development. Curr Res Toxicol 22:2:254–271. doi: 10.1016/j.crtox.2021.07.002. PMID: 34401750; PMCID: PMC8350458.

View Abstract

Gentry R, Rodricks J, Clewell H, Greene T, Chappell G, Lea I, Borghoff S, Yang C, Rathman J, Ribeiro JV, Hobocienski B, Mostrag A. 2021. RE: Response to the Office of Environmental Health Hazard Assessment on comments related to Gentry et al. (2021). Food Chem Toxicol 152:112202. doi: 10.1016/j.fct.2021.112202. Epub 2021 Apr 17. PMID: 33872725.

View Abstract

Gentry R, Greene T, Chappell G, Lea I, Borghoff S, Yang C, Rathman J, Ribeiro JV, Hobocienski B, Mostrag A, Rodricks J, Clewell H. 2021. Integration of evidence to evaluate the potential for neurobehavioral effects following exposure to USFDA-approved food colors. Food Chem Toxicol 151:112097. doi: 10.1016/j.fct.2021.112097. Epub 2021 Mar 4. PMID: 33677041.

View Abstract

Lea IA, Chappell GA, Wikoff DS. 2021. Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence. Mutat Res Genet Toxicol Environ Mutagen 868–869:503389. doi: 10.1016/j.mrgentox.2021.503389. PMID: 34454695.

View Abstract

Heintz MM, Doepker CL, Wikoff DS, Hawks SE. 2021. Assessing the food safety risk of ochratoxin A in coffee: A toxicology-based approach to food safety planning. J Food Sci (open access).

View Abstract

Hackshaw A, Cohen SS, Reichert H, Kansal AR, Chung KC, Ofman JJ. 2021. Estimating the population health impact of a multi-cancer early detection genomic blood test to complement existing screening in the US and UK. Brit J Cancer, open access.

View Abstract

Haddadin Z, Rankin DA, Lipworth L, Suh M, McHenry R, Blozinski A, Salib George S, Fernandez KN, Varjabedian R, Spieker AJ, Shepard DS, Halasa NB. 2021. Respiratory virus surveillance in infants across different clinical settings. J Pediat, DOI: https://doi.org/10.1016/j.jpeds.2021.03.036.

View Abstract

Vágó EK, Nicholson G, Horváth-Puhó E. Hooda N, Fryzek JP, Su J. 2021. Healthcare resource utilization among patients with cold agglutinin disease in Denmark. Curr Med Res Opin, open access.

View Abstract

Chappell, GA. Evidence-based toxicology approaches to integration of mechanistic data in systematic review: Identification, endpoint mapping, and biological organization. Presentation to The Toxicology Forum, Virtual Summer Meeting, July-August 2021.

Luo YS, Chen Z, Blanchette AD, Zhou YH, Wright FA, Baker ES, Chiu WA, Rusyn I. 2021. Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC) cardiomyocytes. Food Chem Toxicol 149, doi: 10.1016/j.fct.2021.111979. PMID: 33450301.

View Abstract

Wikoff D, Fitch S, Borghoff S. Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff):  61st Annual Meeting (virtual) of the Society for Birth Defects Research & Prevention, June 2021.

View Abstract

Blanchett A, Burnett SD, Grimm FA, Rusyn I, Chiu WA. A Bayesian method for population-wide cardiotoxicity hazard and risk characterization using an in vitro human model. Society of Toxicology, meeting session, “Closing the Data Gap: Assessing Population Variability using Next Generation Tools in Toxicology,” March 2021.

View Abstract

Hedgeman E, Nørgaard M, Dalvi T, Pedersen L, Hansen HP, Walker J, Midha A, Shire N, Boothman A-M, Fryzek JP, Rigas J, Mellemgaard A, Rasmussen TR, Hamilton-Dutoit S, Cronin-Fenton D. 2021. Programmed cell death ligand-1 expression and survival in a cohort of patients with advanced non-small cell lung cancer receiving first-line through third-line therapy in Denmark. Cancer Epidemiol 73:101976.

View Abstract

Fitch SE, Payne LE, van de Ligt JLG, Doepker C, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Public Health 21(1):956, doi: 10.1186/s12889-021-10934-2.

View Abstract

Borghoff SJ, Fitch SE, Black MVB, McMullen PD, Andersen ME, Chappell GA. 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124:104977; DOI: 10.1016/j.yrtph.2021.104977.

View Abstract

Whaley P, Blaauboer BJ, Brozek J, Cohen Hubal EA, Hair K, Kacew S, Knudsen TB, Kwiatkowski CF, Mellor DT, Olshan AF, Page MJ, Rooney AA, Radke E, Shamseer L, Tsaioun K, Tugwell P, Wikoff D, Woodruff TJ. 2021. Improving the quality of toxicology and environmental health systematic reviews: What journal editors can do. ALTEX [Internet].

View Abstract

Boice JD, Cohen SS, Mumma MT, Golden AP, Howard SC, Girardi DJ, Dupree Ellis E, Bellamy MB, Dauer LT, Samuels C, Eckerman KF, Leggett RW. 2021. Mortality among workers at the Los Alamos National Laboratory, 1943–2017. Int J Rad Biol, doi: 10.1080/09553002.2021.1917784.

View Abstract

Boice JD, Cohen SS, Mumma MT, Golden AP, Howard SC, Girardi DJ, Dupree Ellis E, Bellamy MB, Dauer LT, Samuels C, Eckerman KF, Leggett RW. 2021. Mortality among workers at the Los Alamos National Laboratory, 1943–2017. Int J Rad Biol, doi: 10.1080/09553002.2021.1917784.

Kempisty DM, Racz L. 2021 (in press). Forever Chemicals: Environmental, Economic, and Social Equity Concerns with PFAS in the Environment. Routledge, Taylor and Francis Group, ISBN 9780367456405.

View Abstract

Proctor DM, Bhat V, Suh M, Reichert H, Jiang X, Thompson CM. 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124:104969, doi.org/10.1016/j.yrtph.2021.104969.

View Abstract

Nielson CM, Bylsma LC, Fryzek JP, Saad HA, Crawford J. 2021. Relative dose intensity of chemotherapy and survival in patients with advanced stage solid tumor cancer: A systematic review and meta-analysis. The Oncologist 26(9):e1609–e1618 (open access), https://doi.org/10.1002/onco.13822.

View Abstract

Wikoff D. The [acceptable daily intake] for low- and no-calorie sweeteners: Origin, interpretation, and application. Invited speaker: Continuing education webinar, Institute for the Advancement of Food and Nutrition Sciences, July 2021.

View Abstract

Suh M, Movva N, Bylsma L, Demont C, Rizzo C, Fryzek J, Nelson CB. Systematic literature review (SLR) of respiratory syncytial virus (RSV) burden and health care utilization (HCU) among infants in the United States (US). Poster presentation [preview] at 37th ICPE (International Conference on Pharmacoepidemiology & Therapeutic Risk Management), virtual conference, August 2021.

View Abstract

Alexander DD, Pastula ST, Riordan AS. 2021. Epidemiology of lung cancer among acrylonitrile-exposed study populations: A meta-analysis. Regul Toxicol Pharmacol 122:104896, doi: 10.1016/j.yrtph.2021.104896, PMID: 33617939.

View Abstract

Broome, C, Patel P, Jiang X, Iglesias-Rodriguez M, Fryzek J. Increased antidepressant use among newly diagnosed patients with cold agglutinin disease compared with other patients in a large US healthcare system. E-poster presentation to European Hematology Association Virtual Congress, June 2021.

Broome CM, Patel P, Jiang X, Iglesias-Rodriguez M, Fryzek J. Increased antidepressant use among newly diagnosed patients with cold agglutinin disease compared with other patients in a large US healthcare system. Poster presentation to European Hematology Association Congress (Abstract EP1180), June 2021, online.

Vágó EK, Nicholson G, Horváth-Puhó E, Hooda N, Fryzek JP, Su J. Healthcare resource utilization among patients with cold agglutinin disease in Denmark. Poster presentation to European Hematology Association Congress (Abstract EP1193), June 2021, online.

Edwards-Hampton S, Bernstein R, Rothberg A, Maltrese L, Cohen S, Coburn S, Pories W, Loper J, Lewis K, Ard J. 2021. Review of key findings from the OPTIWIN trial: Implications and future directions for medical weight management using total diet replacement. Med Res Arch 9(2), doi:10.18103/mra.v9i2.2291.

View Abstract

de Vries RBM, Angrish M, Browne P, Brozek J, Rooney AA, Wikoff DS, Whaley P, Edwards SW, Morgan RL, Druwe IL, Hoffmann S, Hartung T, Thayer K, Avey MT, Beverly BEJ, Falavigna M, Gibbons C, Goyak K, Kraft A, Nampo F, Qaseem A, Sears M, Singh JA, Willett C, Yost EY, Schünemann H, Tsaioun K. 2021. Applying evidence-based methods to the development and use of adverse outcome pathways. ALTEX — Alternatives to Animal Experimentation, 38(2):336–347, doi: 10.14573/altex.2101211.

View Abstract

Gillezeau C, Movva N, Fryzek J, Rabon-Stith K, Brohawn PZ, Gerwen M van, Taioli E. Molecular epidemiology study of interferon gamma (IFN-γ) expression in urothelial bladder cancer (UBC). Poster presentation [preview] at 37th ICPE (International Conference on Pharmacoepidemiology & Therapeutic Rick Management), virtual conference, August 2021.

View Abstract

Bylsma L, Nielson C, Fryzek J, Saad H, Crawford J. Edit chemotherapy relative dose intensity, overall survival, and hematologic toxicity in solid-tumor cancer patients: A literature review and meta-analysis. Poster presentation [preview] at 37th ICPE (International Conference on Pharmacoepidemiology & Therapeutic Rick Management), virtual conference, August 2021.

View Abstract

Vágó EK, Nicholson G, Horváth-Puhó E, Hooda N, Fryzek J, Su J. Healthcare resource utilization among patients with cold agglutinin disease in Denmark. E-poster presentation to European Hematology Association Virtual Congress, June 2021.

Dirven H, Vist GE, Bandhakavi S, Mehta J, Fitch SE, Pound P, Ram R, Kincaid B, Leenaars CHC, Chen M, Wright RA, Tsaioun K. 2021. Performance of preclinical models in predicting drug-induced liver injury in humans: A systematic review. Nature, Scientific Reports; open access.

View Abstract

Malcolm W, Fisher K, Wood CT, Movva N, Suh M, Wolf Z, Balu S, Sendak M, Hintze B, White M, Fryzek J, Nelson CB. Infant lower respiratory tract infections, including those caused by RSV, are significantly below historical levels during the COVID-19 pandemic. Pediatrics Academic Societies 2021, April–May 2021.

Chappell GA, Heintz MM, Borghoff SJ, Doepker CL, Wikoff DS. 2021. Lack of potential carcinogenicity for steviol glycosides — Systematic evaluation and integration of mechanistic data into the totality of evidence. Food Chem Toxicol 150:112045.

View Abstract

Felter SP, Zhang X, Thompson C. 2021. Butylated hydroxyanisole: Carcinogenic food additive to be avoided or harmless antioxidant important to protect food supply? Regul Toxicol Pharmacol 121:104887.

View Abstract

Klosterbuer A, Cekola P, Neutel JM, Jiang X, Cohen SS, Araujo Torres K. 2021. Effect of diabetes-specific oral nutritional supplements on postprandial glycemic response in adults with type 2 diabetes mellitus. Poster presented at ASPEN Nutrition Science & Practice Conference, March 2021.

Fergie J, Gonzales T, Suh M, Jiang X, Fryzek J, Hooda N, Howard A, Bloomfield A. Higher-risk congenital heart disease (CHD) among children aged ≤24 months with respiratory syncytial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH) at RSV season before and after the 2014 American Academy of Pediatrics (AAP) guidance. California Association of Neonatologists’ 27th Annual Cool Topics in Neonatology Conference, March 2021.

View Abstract

Wikoff DS, Urban JD, Ring C, Britt J, Fitch S, Haws LC. 2021. Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression. Toxicol Sci 179(2):162-182, https://doi.org/10.1093/toxsci/kfaa171.

View Abstract

Dainelli L, Luo DR, Cohen SS, Marczewska A, Ard JD, Coburn SL, Lewis KH, Loper J, Matarese LE, Pories WJ, Rothberg AE. 2021. Health-related quality of life in weight loss interventions: Results from the OPTIWIN trial. Int J Environ Res Public Health 18:1785

Chappell GA, Heintz MM, Haws LC. 2021. Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development. Curr Res Toxicol 2:30–41.

View Abstract

Chappell GA, Wikoff DS, Thompson CM. 2021. Assessment of mechanistic data for hexavalent chromium-induced rodent intestinal cancer using the key characteristics of carcinogens. Toxicol Sci 180(1):38–50.

View Abstract

Fergie J, Gonzales T, Suh M, Jiang X, Fryzek JP, Hooda N, Howard A, Bloomfield A. Higher-risk congenital heart disease (CHD) among children aged ≤24 months with respiratory syncytial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH). 37th Annual Children’s National Symposium: ECMO and the Advanced Therapies for Cardiovascular and Respiratory Failure, Feb 2021.

View Abstract

2020

Levin-Sparenberg E, Bylsma LC, Lowe K, Sangare L, Fryzek JP, Alexander DD. 2020. A systematic literature review and meta-analysis describing the prevalence of KRAS, NRAS, and BRAF gene mutations in metastatic colorectal cancer. Gastroenterol Res 13(5):184–198. doi: 10.14740/gr1167.

View Abstract

Cohen S, Reichert H, Kansal AR, Chung KC. Improved efficiency of cancer screening with multi-cancer early detection test. ISPOR (International Society for Pharmacoeconomics and Outcomes Research, Inc.) virtual conference, May 2020.

Cekola P, Henrickson A, Cohen SS, Reichert H, Ararujo Torres K, Hulsey A. Growth and tolerance with an amino acid formula at a children’s center: A two-year retrospective review. Poster presented to North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), November 2020.

Blanchett A, Burnett SD, Grimm FA, Rusyn I, Chiu WA. A Bayesian new approach method for human population-wide risk characterization of cardiotoxicity. Presentation to Texas A&M University Toxicology Seminar Series, November 2020.

Blanchett A, Burnett SD, Grimm FA, Rusyn I, Chiu WA. An in vitro-in silico model for characterizing hazard and population variability in cardiotoxicity induced by environmental chemicals. Poster presentation at the Lone Star Society of Toxicology annual meeting and the Texas A&M Annual CVM Trainee Symposium; oral presentation at the Texas A&M Toxicology Seminar Series and the 2020 SOT Annual Meeting,Texas Edition virtual meeting, 2020.

Blanchette A. Bioiformatic tools for research. Presented during annual Toxicology Bootcamp, February 2020 and April 2021.

Bhat VS, Cohen SM, Gordon EB, Wood CE, Cullen JM, Harris MA, Proctor DM, Thompson CM. 2020. An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: A case study with hexavalent chromium, captan, and folpet. Crit Rev Toxicol 50(8) (open access).

View Abstract

Minor G, Yamamoto S, Cekola P, Cohen SS, Huhman MB, Araujo Torres K. 2020. Meeting nutritional needs of the enterally-fed child with neurological impairment. J Clin Nutr Dietet 6(4):3.

View Abstract

Wikoff D, Lewis JR, Erraguntla N, Franzen A, Foreman J. 2020. Facilitation of risk assessment with evidence-based methods — A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertainty. Regul Toxicol Pharmacol (in press), journal pre-press online.

View Abstract

Cohen SS, Roger VL, Weston SA, Jiang R, Movva N, Yusuf AA, Chamberlain AM. 2020. Evaluation of claims-based computable phenotypes to identify heart failure patients with preserved ejection fraction. Pharmacol Res Persp (open access).

View Abstract

Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D, Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118:104788.

View Abstract

Fryzek J, Bylsma L, Mease K, Movva N, Welsh BT, Wood M. 2020. Critical insights into nonclinical toxicology and real-world evidence essential for a successful rare disease product launch. EpidStrategies, Inc., white paper.

White Paper

View Abstract

Mahony CA, Bowtell P, Huber M, Kosemund K, Pfuhler S, Zhu T, Barlow S, McMillan DA. 2020. Threshold of toxicological concern (TTC) for botanicals — Concentration data analysis of potentially genotoxic constituents to substantiate and extend the TTC approach to botanicals. Food Chem Toxicol 138:111182.

View Abstract

Gage SM, Reichert H. 2020. Determining the incidence of needle-related complications in hemodialysis access: We need a better system. J Vascular Access.

View Abstract

Elbeddini A, Hooda N, Yang L. 2020. Role of Canadian pharmacists in managing drug shortage concerns amid the COVID-19 pandemic. Canadian Pharmacists J, doi: 10.1177/1715163520929387.

View Abstract

Boice JD, Cohen SS, Mumma MT, Chen H, Golden AP, Beck HL, Till JE. 2020. Mortality among US military participants at eight aboveground nuclear weapons test series. Int J Radiat Biol, doi: 10.1080/09553002.2020.1787543.

View Abstract

Ard, JD, Lewis KH, Cohen SS, Rothberg A, Coburn SL, Loper J. Matarese L, Pories WJ, Periman S. 2020. Differences in treatment response to a total diet replacement intervention vs. a food-based intervention: A secondary analysis of the OPTIWIN trial. Obesity Sci Pract, doi: 10.1002/osp4.444.

View Abstract

Suh M, Jiang X, Movva N, Fryzek J, Bylsma L, Rizzo C, Nelson CB. Hospitalizations and emergency department visits for respiratory syncytial virus among infants aged <1 year in the United States: An analysis of nationwide inpatient and emergency room data. Presentation to IDWeek virtual conference on infectious disease, October 2020.

View Abstract

Fergie J, Gonzales T, Suh M, Jiang X, Fryzek, J, Howard A, Bloomfield A. 2020. Respiratory syncytial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH) among children aged ≤24 months at the start of RSV season with bronchopulmonary dysplasia/chronic lung disease of prematurity (BPD/CLDP) before and after the 2014 American Academy of Pediatrics (AAP) policy. Presentation to IDWeek virtual conference on infectious disease, October 2020.

View Abstract

Fergie J, Gonzales T, Suh M, Jiang X, Fryzek, J, Howard A, Bloomfield A. 2020. Medically attended respiratory syncytial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH) among children aged ≤24 months at RSV season start with higher-risk congenital heart disease (CHD) before and after the 2014 American Academy of Pediatrics (AAP) policy. Presentation to IDWeek virtual conference on infectious disease, October 2020.

Loper J, Lewis KH, Rothberg A, Auriemma A, Coburn SL, Cohen SS, Matarese L, Pories WJ, Jiang X, Periman S, Ard JD. Weight change in participants completing meal replacement program is related to level of engagement. Obesity Week virtual conference, 2020.

Cohen S, Reichert H, Kansal AR, Chung KC. Improved efficiency of cancer screening with multi-cancer early detection test. ISPOR (International Society for Pharmacoeconomics and Outcomes Research, Inc.) virtual conference, May 2020.

Chamberlain AM, Reading SR, Dluzniewski PJ, Killian JM, Weston SA, Bjorkenstam E, Cohen SS. Identification and characterization of the high cardiovascular risk patient with multiple events. CSANZ (Cardiac Society of Australia and New Zealand) virtual conference, Dec 2020.

Rankin DA, Haddadin Z, Lipworth L, Fryzek J, Suh M, Shepard DS, McHenry R, Varjabedian R, Fernandez KN, Rizzo C, Nelson CB, Halasa NB. Comparison of clinical presentations and burden of respiratory syncytial virus in infants across three distinct healthcare settings. IDWeek virtual conference on infectious disease, October 2020.

View Abstract

Haddadin Z, Rankin DA, Lipworth L, Fryzek J, Suh M, Shepard DS, McHenry R, Varjabedian R, Fernandez KN, Rizzo C, Nelson CB, Halasa NB. Distribution of respiratory viral pathogens in infants across different clinical settings from December 2019 to April 2020. IDWeek virtual conference on infectious disease, October 2020.

View Abstract

Haddadin Z, Rankin DA, Lipworth L, Fryzek J, Suh M, Shepard DS, McHenry R, Varjabedian R, Fernandez KN, Rizzo C, Nelson CB, Halasa NB. Clinical characteristics of common respiratory viruses detected in infants across different clinical settings. IDWeek virtual conference on infectious disease, October 2020.

View Abstract

Shepard DS, Perloff J, Jiang S, Suh M, Fryzek J, Bowser D, Rizzo C, Nelson CB. Impacts of age and season on rates of hospitalization for respiratory syncytial virus (RSV) in infants in the United States and their use of mechanical ventilation and charges. IDWeek virtual conference on infectious disease, October 2020.

View Abstract

Eskes C, Corsini E, Hanley V, Karadjova I, Kopp-Schneider A, Suh M, Alves P, Clewell R, Cotgreave I, Navas J, Piersma A, Westmoreland C. 2020. ESAC opinion on the scientific validity of the bioelution test method. In: Viegas Barroso J (ed), EUR 30281 EN. Publications Office of the European Union, Luxembourg, ISBN 978-92-76-20004-8 (online), doi:10.2760/023005 (online), JRC121143.

View Abstract

Christiansen CF, Farkas DK, Fryzek JP, Romagnani P, Nørgaard M, Rothman KJ, Toft Sørensen H. Risk and prognosis of cancer after acute kidney injury. Presentation to the 36th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, Berlin, Germany, August 2020.

View Abstract

Vago EK, Nicholson G, Horvath-Puho E, Fryzek JP, Su J. Healthcare resource utilization among cold agglutinin disease (CAD) patients in Denmark. Presentation to ISPOR Europe 2020 virtual conference, November 2020.

View Abstract

Krehnbrink M, Patel K, Byerley J, Tarantino H, Peyser B, Payne L, Foley K, Latessa R. 2020. Physician preceptor satisfaction across curricula: Comparing longitudinal integrated clerkships and traditional block rotations. Teach Learn Med 32(2):176–183. doi: 10.1080/10401334.2019.1687304.

View Abstract

Thompson CM, Donahue DA, Hobbs C, Costecalde Y, Franzen A, Suh M, Proctor DM, Harris MA. 2020. Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice. Regul Toxicol Pharmacol 116, open access.

View Abstract

Fergie J, Suh M, Jiang X, Fryzek JP, Gonzales T. 2020. Respiratory syncytial virus and all-cause bronchiolitis hospitalizations among preterm infants using the Pediatric Health Information System (PHIS). J Infectious Dis: open-access accepted ms. ahead of print.

View Abstract

Dronin-Fenton D, Dalvi T, Movva N, Pedersen I, Hansen H, Fryzek J, Mellemgaard A, Rasmussen T, Klein A, Hamilton-Dutoit S, Nørgaard M. PD-L1 expression and survival in stage III unresectable non-small cell lung cancer patients in Denmark. Accepted for presentation to a virtual meeting (due to COVID-19) of the European Society for Medical Oncology (ESMO), abstract #2865, August 2020.

View Abstract

Elbeddini A, Hooda N, Gazarin M, Webster P, McMillan J. 2020. Irinotecan-associated dysarthria in patients with pancreatic cancer: A single site experience. Am J Case Rep, doi: 10.12659/AJCR.924058.

View Abstract

Whaley P, Aiassa E, Beausoleil C, Beronius A, Bilotta, G, Boobis A, de Vries R, Hanberg A, Hoffman S, Hunt N, Kwiatkowski CF, Lam J, Lipworth S, Martin O, Randall, N, Rhomberg L, Rooney AA, Holger J, Schünemann HJ, Wikoff D, Wolffe T, Halsall C. 2020. Recommendations for the conduct of systematic reviews in toxicology and environmental health research (COSTER). Environ Int 143:105926.

View Abstract

Chesney A, Welsh B, Kimzey A, Lansita J. The process and challenges of deriving exposure-based limits for toxicological risk assessment for components and impurities present in cell therapy products with case studies. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Bell S, Abedini J, Ceger P, Chang X, Cook B, Karmaus AL, Lea I, Mansouri K, Phillips J, McAfee E, Rai R, Rooney J, Sprankle C, Tandon A, Allen D, Casey W, Kleinstreuer N. 2020. An integrated chemical environment with tools for chemical safety testing. Toxicol in Vitro 67:104916.

View Abstract

Zorn KM, Foil DH, Russo DP, Clark AM, Hillwalker W, Feifarek D, Jones F, Klaren W, Brinkman A, Ekins S. Generation of machine-learning models to anticipate endocrine disruption. Society of Toxicology Annual Meeting, virtual, 2020.

View Abstract

Brinkman AM*, Klaren WD*, Feifarek DJ, Hillwalker W, Jones F, Zorn KM, Ekins S. Use of a weighted scheme for the interpretation and contextualization of in vitro and in silico-derived estrogenic endpoints. Society of Toxicology Annual Meeting, virtual (*equal contributors), 2020.

View Abstract

Chappell GA, Thompson CM, Wolf JC, Cullen JM, Klaunig JE, Haws LC. 2020. Assessment of the mode of action underlying the effects of GenX in mouse liver and implications for assessing human health risks. Toxicol Pathol 48(3):494–508, doi: 10.1177/0192623320905803. PMID: 32138627.

View Abstract

Urban JD, Wikoff DS, Chappell GA, Harris C, Haws LC. 2020. Systematic evaluation of mechanistic data in assessing in utero exposures to trichloroethylene and development of congenital heart defects. Toxicology 436:152427, doi: 10.1016/j.tox.2020.152427. PMID: 32145346.

View Abstract

Keele GR, Quach BC, Israel JW, Chappell GA, Lewis L, Safi A, et al. 2020. Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation. PLoS Genet 16(1):e1008537, doi: 10.1371/journal.pgen.1008537.

View Abstract

Mavunda K, Jiang X, Ambrose CS. 2020. Prevalence and clinical characteristics of perinatal chronic lung disease by infant gestational age. J Neonatal-Perinatal Med, DOI: 10.3233/NPM-200412.

View Abstract

Grimm FA, Klaren WD, Li X, Lehmler HJ, Karmakar M, Robertson LW, Chiu WA. Rusyn I. 2020. Cardiovascular effects of polychlorinated biphenyls and their major metabolites. Environ Health Persp 128(7):77008, PMID: 32701041.

View Abstract

Zorn KM, Foil DH, Lane TR, Russo DP, Hillwalker W, Feifarek DJ, Jones F, Klaren WD, Brinkman AM, Ekins S. 2020. Machine learning models for estrogen receptor bioactivity and endocrine disruption prediction. Environ Sci Technol 54(19):12202–12213, PMID: 32857505.

View Abstract

House JS, Grimm FA, Klaren WD, Dalzell A, Kuchi S, Zhang S, Lenz K, Boogaard PJ, Ketelsegers HB, Gant TW, Wright FA, Rusyn I. 2020. Grouping of UVCB substances with new approach methodologies (NAMs) data. ALTEX 38(1):123–137, PMID: 33086383 [preprint].

View Abstract

Zorn KM, Foil DH, Lane TR, Hillwalker W, Feifarek DJ, Jones F, Klaren WD, Brinkman AM, Ekins S. 2020. Comparing machine learning models for aromatase (P450 19A1). Environ Sci Technol 54(23):15546–15555, PMID: 33207874.

View Abstract

Zorn KM, Foil DH, Lane TR, Hillwalker W, Feifarek DJ, Jones F, Klaren WD, Brinkman AM, Ekins S. 2020. Comparison of machine learning models for the androgen receptor. Environ Sci Technol 54(21):13690–13700, PMID: 33085465.

View Abstract

Heintz, MM, McRee, R, Kumar, R, Baldwin, WS. 2020. Gender differences in diet-induced steatotic disease in Cyp2b-null mice. PLoS ONE 15(3):e0229896.

View Abstract

Watanabe M, Rogers JM. 2020. Introduction to “The Trouble with Plastics” special issue. Birth Defects Res 112:1297–1299.

View Abstract

Saldanha G, Ording AG, Bylsma LC, Darvalics B, Solis D, Tang JY, Sorensen HT, Fryzek J. 2020. High-frequency basal cell carcinoma in Danish patients: Prevalence and consistency. J Eur Acad Dermatol Venereol [Early View], http://dx.doi.org/10.1111/jdv.16512.

View Abstract

Chappell GA, Wikoff DS, Doepker CL, Borghoff SJ. 2020. Lack of potential carcinogenicity for acesulfame potassium — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 141:111375 [open access].

View Abstract

Chappell GA, Britt JK, Borghoff, SJ. 2020. Systematic assessment of mechanistic data for FDA-certified food colors and neurodevelopmental processes. Food Chem Toxicol 140:111310 [open access].

View Abstract

Su J, Bylsma LC, Jiang X, Morales Arias J, Jain N, Nordyke RJ. 2020. Healthcare resource utilization among commercially insured patients with cold agglutinin disease in the United States. J Med Econ, DOI: 10.1080/13696998.2020.1764006.

View Abstract

Bylsma LC, Dean R, Lowe K, Sangare L, Alexander D, Fryzek J. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis of patient and study characteristics. Poster for Society of Toxicology, virtual annual meeting, 2020.

View Abstract

Saldanha G, Ording AG, Bylsma LC, Darvalics B, Solis D, Tang JY, Sorensen HT, Fryzek J. 2020. High frequency basal cell carcinoma (BCC) in Danish patients: Prevalence and consistency. J Eur Acad Dermatol Venereol Apr 20 doi: 10.1111/jdv.16512 (Epub ahead of print).

View Abstract

Haws L (session co-chair). Introduction to “Use of New Approach Methods in Risk Characterization of PFAS: Challenges and Opportunities.” 44th Annual Winter Meeting, the Toxicology Forum, Tysons, VA, Jan 2020 (see: https://dialogue.toxforum.org/d/do/894).

Vater S. Update: New data requirements for sunscreen over the counter additives—Challenges and opportunities. Presentation at 44th Annual Winter Meeting, the Toxicology Forum, Tysons, VA, Jan 2020 (see: https://dialogue.toxforum.org/d/do/913).

Antonijevic T, Shah I. Predicting subchronic and chronic animal toxicity from in vitro high content imaging data using PBTK and machine learning. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Franzen A, Borghoff SJ. An adverse outcome pathway for renal tumors in male rats through chemical induction of aa2u-globuline (a2u) nephropathy (a2u-N). Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Bylsma LC, Dean R, Lowe K, Sangare L, Alexander D, Fryzek J. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis of patient and study characteristics. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Henderson RG, Franzen A, Franke K, Payne L, Schmitt D, Wikoff D. Creating a literature database for cannabidiol (CBD): Systematic evidence mapping. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Ring C, Fitch S, Haws L, Harris M, Wikoff D. Quantitative integration of dose-response data for relative potency estimates of dioxin-like chemicals. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Suh M, Verwiel A, Proctor D. Oral and inhalation bioaccessibility of cobalt and nickel in metal alloys: A critical consideration for site-specific human health risk assessments and read across. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Thompson CM, Ring C, Pham L, Chappell GA, Haws LC. Assessment of the relevance of toxicological findings in the development of an oral reference dose for GenX. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Wikoff D, Franzen A, Chappell G, Harris M, Thompson C. Systematic characterization of hexavalent chromium and potential female reproductive outcomes: Application of US EPA critical appraisal tools and stepwise inclusion of mechanistic data. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

View Abstract

Pham LL, Borghoff SJ, Thompson CM. 2020. Comparison of threshold of toxicological concern (TTC) values to oral reference dose (RfD) values. Regul Toxicol Pharmacol 113:104651 [open access].

View Abstract

Broome CM, Cunningham JM, Mullins M, Jiang X, Bylsma LC, Fryzek JP, Rosenthal A. 2020. Increased risk of thrombotic events in cold agglutinin disease: A 10-year retrospective analysis. Res Prac Thrombosis Haemostasis, open access.

View Abstract

Bell S, Mansouri K, Phillips J, Chang X, Abedini J, Karmaus AL, Lea I, Rai R, Allen DG, Casey W, Kleinstreuer NC. NCEATM computational tools and resources supporting alternative test method development and evaluation. Presented at the 59th Annual Meeting of Society of Toxicology, Anaheim CA, March 2020. Abstract #2976-P607.

View Abstract

Saili KS, Antonijevic T, Zurlinden TJ, Shah I, Deisenroth C, Knudsen TB. 2020. Molecular characterization of a toxicological tipping point during human stem cell differentiation. Reprod Toxicol 91:1–13 (selected as journal’s best paper of 2020).

View Abstract

Heintz MM, Olack EM, Baldwin WS. Human CYP2B6 is an anti-obesity enzyme that produces active α-linolenic acid metabolites. Society of Toxicology meeting, Anaheim, CA, March 2020.

View Abstract

Heintz MM, McRee R, Kumar R, Baldwin WS. Gender differences in diet-induced nonalcoholic steatohepatitis (NASH) in Cyp2b-null mice. Society of Toxicology meeting, Anaheim, CA, March 2020.

View Abstract

Wikoff DS, Bennett DC, Brorby GP, Franke KS. 2020. Evaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth. Food Addit Contam Part A; DOI: 10.1080/19440049.2020.1727963.

View Abstract

Yamamoto S, Allen K, Jones KR, Cohen SS, Reyes K, Huhmann MB. 2020. Meeting calorie and protein needs in the critical care unit: A prospective observational pilot study. Nutr Metab Insights 13:1–7; doi: 10.1177/1178638820905992.

View Abstract

Rogers EN, Mihalchik AL, Gad, SC. 2020. Comparison and analysis of discrepancies among commonly used Cramer decision tree methods in Toxtree software. In: 2020 Annual Meeting Abstract Supplement, Society of Toxicology, Abstract no. 1517.

View Abstract

Thompson CM, Gentry R, Fitch S, Lu K, Clewell HJ. 2020. An updated mode of action and human relevance framework evaluation for formaldehyde-related nasal tumors. Crit Rev Toxicol 50(10):919–952, DOI: 10.1080/10408444.2020.1854679.

View Abstract

Gentry R, Thompson CM, Franzen A, Salley J, Albertini R, Lu K, Greene T. 2020. Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia. Crit Rev Toxicol 50(10):885–918, DOI: 10.1080/10408444.2020.1854678.

View Abstract

ApSimon M, Johnston C, Winder B, Cohen SS, Hopkins B. 2020. Narrowing the protein deficit gap in critically ill patients using a very high-protein enteral formula. Nutr Clin Practice 0:1–7, DOI: 10.1002/ncp.10472.

View Abstract

Perry C, Rish W, Ring C, Mittal L, Harris M. Use of probabilistic risk assessment and physiologically based pharmacokinetic modeling in supporting soil remedial objectives for dioxins and furans at a Canadian site. Poster for Society for Risk Analysis, Virtual Annual Meeting, 2020.

View Abstract

Nelson CB, Broor S, Fryzek J, Wairagkar NS. 2020. Respiratory syncytial virus. Chapter 59 in: Vashishtha VM (Ed), IAP Textbook of Vaccines, Second Edition. Indian Academy of Pediatrics.

2019

Bylsma LC, Gillezeau C, Garawin TA, Kelsh MA, Fryzek JP, Sangaré L, Lowe KA. 2019. Prevalence of RAS and BRAF mutations in metastatic colorectal cancer patients by tumor sidedness: A systematic review and meta-analysis. Cancer Med Dec 19, doi: 10.1002/cam4.2747.

View Abstract

Benson SM, Maskrey JR, Nembhard MD, Unice KM, Shirley MA, Panko JM. 2019. Evaluation of personal exposure to surgical smoke generated from electrocautery instruments: A pilot study. Ann Work Expos Health wxz070; open access.

View Abstract

Wikoff DS, Chappell GA, Fitch S, Doepker CL, Borghoff SJ. 2019. Lack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135:110866.

View Abstract

Blanchette A., Grimm FA, Dalaijamts C, Hsieh NH, Ferguson K, Luo YS, Rusyn I, Chiu WA. Thorough QT/QTc in a dish: An in vitro human model that accurately predicts clinical concentration-QTc. Poster presentation at the 2018 Texas A&M Toxicology Symposium; oral presentation at Lone Star Society of Toxicology 2018 conference; poster presentation at SOT, 2018–2019.

Blanchette AD, Grimm FA, Dalaijamts C, Hsieh NH, Ferguson K, Luo YS, Rusyn I, Chiu WA. 2019. Thorough QT/QTc in a dish: An in vitro human model that accurately predicts clinical concentration‐QTc relationships. Clin Pharmacol Therapeut 105(5):1175–1186, doi: 10.1002/cpt.1259. PMID: 30346629.

View Abstract

Burnett SD, Blanchette AD, Grimm FA, House JS, Reif DM, Wright FA, Chiu WA, Rusyn I. 2019. Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes. Toxicol Appl Pharmacol 381:114711, doi: 10.1016/j.taap.2019.114711. PMID: 31425687.

View Abstract

Czerkies LM, Finn KL, Kineman BD, Reichert HA, Cohen SS, Carvalho RS. 2019. Use of a partially hydrolyzed 100% whey-based infant formula with Lacrobacillus reuteri in infants with caregiver-perceived intolerance. J Pedat Health Nutr, Open Access.

View Abstract

Marschke S, Rish W, Mauro J. 2019. Radiation exposures from the beneficial use of alumina production residue. J AWWA online.

View Abstract

Krelder ML, Unice KM, Panko JM. 2019. Human health risk assessment of tire and road wear particles (TRWP) in air. Hum Ecol Risk Assess, open access.

View Abstract

Chappell GA, Borghoff SJ, Pham L, Doepker CL, Wikoff DS. 2019. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135:110898.

View Abstract

Bylsma LC, Ording AG, Rosenthal A, Öztürk B, Fryzek JP, Arias JM, Röth A, Berentsen S. 2019. Occurrence, thromboembolic risk, and mortality in Danish patients with cold agglutinin disease. Blood Advances 3(20):2980–2985.

View Abstract

Thompson C, Chappell G, Cullen J, Wolf JC, Haws L. Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic Meeting, Durham, NC, August 2019.

Chappell GA, Thompson CM, Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.

Thompson CM. The useful chemistry of perfluorinated compounds: Managing safety. The sticky subject of non-stick: Regulatory science challenges of per- and poly-fluorinated compounds (PFAS). Texas A&M University Interdisciplinary Faculty of Toxicology Training Program, 2019 Annual Regulatory Science Symposium. August 20, 2019.

Andersen ME, Gentry PR, Swenberg JA, Mundt KA, White KW, Thompson C, Bus J, Sherman JH, Greim H, Bolt H, Marsh GM, Checkoway H, Coggon D, Clewell HJ. 2019. Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop. Regul Toxicol Pharmacol 106:210–223.

View Abstract

Clewell RA, Thompson CM, Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301:112–127.

View Abstract

Chappell G, Rager J, Wolf J, Babic M, Leblanc, Ring C, Harris MA, Thompson CM. 2019. Comparison of gene expression responses in the small intestine of mice following exposure to three carcinogens using the S1500+ gene set informs a potential common adverse outcome pathway. Toxicol Pathol 47(7):851-864.

View Abstract

van de Ligt J, Borghoff SJ, Yoon M, Ferguson LJ, DeMaio W, McClanahan RH. 2019. Nondetectable or minimal detectable residue levels of N-(n-butyl) thiophosphoric triamide in bovine tissues and milk from a 28-d NBPT dosing study. Translat An Sci 3(4).

View Abstract

Cekola P, Henrikson A, Reichert H, Cohen S, Huhmann M, Torres KA. Clinical use and safety of an amino acid-based infant formula in a real world setting. Poster at NASPGHAN, Chicago, IL, October 2019.

Cohen SS, Roger VL, Weston SA, Jiang R, Movva N, Yusuf A, Chamberlain AM. Development of computable phenotypes to identify heart failure patients with preserved ejection fraction. Poster at International Society for Pharmacoepidemiology, Philadelphia, PA, August 2019.

Boice JD Jr, Cohen SS, Mumma MT, Ellis ED. 2019. The Million Person Study, whence it came and why. Int J Radiat Biol 4:1–14, doi: 1080/09553002.2019.1589015.

View Abstract

Chamberlain AM, Cohen SS, Killian JM, Monda KL, Weston SA, Okerson T. 2019. Lipid-lowering prescription patterns in patients with diabetes mellitus or cardiovascular disease. Am J Cardio 124(7):995–1001.

View Abstract

Latessa R, Keen S, Byerley J, Foley K, Payne L, Conner K, Tarantino T, Peyser B, Steiner D. 2019. The North Carolina community preceptor experience: Third study of trends over twelve years. Acad Med 94(5):715–722. doi: 10.1097/ACM.0000000000002571.

View Abstract

Bylsma LC, Dean R, Lowe K, Sangaré L, Alexander DD, Fryzek JP. 2019. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta‐analysis of patient and study characteristics. Cancer Med 8(12):5800–5809.

View Abstract

Hooda N, Quinn E, DeAngelis C, Pasetka M, McFarlane T. 2019. Delayed CINV in FOLFOX chemotherapy: A retrospective chart review comparing two Ontario hospitals. Poster presented at the Canadian Association for Pharmacy in Oncology Annual Conference, Halifax, NS, April 2019.

Hooda N, McFarlane T, Pasetka M, DeAngelis C. Chemotherapy-induced nausea and vomiting (CINV) in colorectal cancer (CRC) patients undergoing FOLFOX Chemotherapy: A retrospective chart review comparing two Ontario hospitals. Abstract accepted for publication in J Pharmacy Pharmaceut Sci. Poster presented at the Canadian Society for Pharmaceutical Sciences Annual Conference, Vancouver, BC, May 2019.

Hooda N, Quinn E, DeAngelis C, Pasetka M, McFarlane T. 2019. Delayed CINV in FOLFOX chemotherapy: A retrospective chart review comparing two Ontario hospitals. J Oncol Pharmacy Prac (abstract 22), doi:10.1177/1078155219834495.

View Abstract

Plummer IH, Johnson CJ, Chesney AR, Pedersen JA, Samuel MD. 2019. Mineral licks as reservoirs for chronic wasting disease prions. PlosONE 13(5):e0196745.

View Abstract

Mease K. Managing immunogenicity in the absence of an ADA assay is no monkey business (case study). Presentation at 25th annual Charles River Biotech Symposium, Carlsbad, CA, September 8–11, 2019.

View Abstract

Nordyke RJ, Reichert H, Bylsma LC, Jackson JJ, Gage SM, Fryzek J, Roy-Chaudhury P, Lithgow T. 2019. Costs attributable to arteriovenous fistula and arteriovenous graft placements in hemodialysis patients with Medicare coverage. Am J Nephrol [Online first, abstract only]: doi: 10.1159/000502507.

View Abstract

Thompson CM, Fitch SE, Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol 39:1267–1282.

View Abstract

Yoon M, Ring C, Van Landingham CB, Suh M, Song G, Antonijevic T, Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380:114695

View Abstract

Fitch S, Goyak K, Green Maia, Grimm F, Wikoff D. 2019. Estrogen-mediated outcomes for alkylphenols via an adverse outcome pathway (AOP) construct. Open Science Framework, August.

View Abstract

Fergie J, Gonzales T, Jiang X, Fryzek J, Rizzo CP. Respiratory syncitial virus hospitalizations (RSVH) and all-cause bronchiolitis hospitalizations (BH) among 29-34 weeks gestational age (wGA) preterm infants before and after the 2014 American Academy of Pediatrics (AAP) immunoprophylaxis policy change using the Children’s Hospital Association’s Pediatric Health Information System (PHIS). Poster presentation at IDWeek, Washington, DC, October 2–6, 2019.

View Abstract

Röth A,  Fryzek J, Jiang X, Reichert H, Morales J, Broome CM. Seasonal patterns of thromboembolic events in cold agglutinin disease (CAD) in the United States. Presentation at 81st Annual Meeting of the Japanese Society of Hematology, Tokyo, Japan, October 11–13, 2019.

View Abstract

Röth A, Fryzek J, Jiang X, Reichert H, Morales J, Broome CM. Seasonal patterns of anemia, hemolytic markers, healthcare resource utilization, and thromboembolic events in cold agglutinin disease. Presentation at German Society for Hematology and Medical Oncology, Berlin, Germany, October 11–14, 2019.

View Abstract

Proctor D. Use of the latest science in cancer risk assessment for hexavalent chromium: Is it time to step away from the default regulatory approaches? Invited presentation to the International Union of Toxicology (IUTOX) / International Congress of Toxicology (ICT) meeting, Honolulu, HI, June 17, 2019.

Insley AL,.Maskrey JR, Hallett LA, Reid RCD, Hynds ES, Winter C, Panko JM. Occupational survey of airborne metal exposures to welders, metalworkers, and bystanders in small fabrication shops. Poster at American Industrial Hygiene Conference and Exhibition, Minneapolis, MN, May 20–24, 2019.

Lewis L, Chappell GA, Kobets T, O’Brian BE, Sangaraju D, Kosyk O, Bodnar W, Tretyakova NY, Pogribny IP, Rusyn I. 2019. Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues. Arch Toxicol 93(3):791–800, doi: 10.1007/s00204-018-2374-x. PMID: 30552462.

View Abstract

Lewis L, Borowa-Mazgaj B, de Conti A, Chappell GA, Luo YS, Bodnar W, et al. 2019. Population-based analysis of DNA damage and epigenetic effects of 1,3-butadiene in the mouse. Chem Res Toxicol 32(5):887–898, doi: 10.1021/acs.chemrestox.9b00035. PMID: 30990016.

View Abstract

Boice JD Jr, Ellis ED, Golden AP, Zablotska LB, Mumma MT, Cohen SS. 2019. Sex-specific lung cancer risk among radiation workers in the Million Person Study and TB-fluoroscopy patients. Int J Radiat Biol Jan 7:1–36.

View Abstract

Hopkins B, Cohen SS, Irvin SR, Alberda C. 2019. Achieving protein targets in the ICU using a specialized high-protein enteral formula: A quality improvement project. Nutr Clin Practice, DOI: 10.1002/ncp.10364

View Abstract

Unice KM, Weeber MP, Abramson MM, Reid RCD, van Gils JAG, Markus AA, Vethaak AD, Panko JM. 2019. Characterizing export of land-based microplastics to the estuary – Part II: Sensitivity analysis of an integrated geospatial microplastic transport modeling assessment of tire and road wear particles. Sci Tot Environ 646:1650–1659.

View Abstract

Unice KM, Weeber MP, Abramson MM, Reid RCD, van Gils JAG, Markus AA, Vethaak AD, Panko JM. 2019. Characterizing export of land-based microplastics to the estuary — Part I: Application of integrated geospatial microplastic transport models to assess tire and road wear particles in the Seine watershed. Sci Tot Environ 646:1639–1649.

View Abstract

Panko JM, Hitchcock KM, Fuller GW, Green D. 2019. Evaluation of tire wear contribution to PM2.5 in urban environments. Atmosphere 10(2):99, https://doi.org/10.3390/atmos10020099.

View Abstract

Insley AL, Maskrey JR, Hallett LA, Reid RCD, Hynds ES, Winter C, Panko JM. 2019. Occupational survey of airborne metal exposures to welders, metalworkers, and bystanders in small fabrication shops. J Occup Environ Hyg 16:6:410–421, DOI: 10.1080/15459624.2019.1603389.

View Abstract

Ring CL, Rish WR, Brorby GL. Prioritization of eight PFAS by population exposure and reference-dose uncertainty. Poster session at SETAC North America Focused Topic Meeting “Environmental Risk Assessment of PFAS”, Durham, NC, August 2019.

Wikoff D, Haws L, Ring C, Budinsky R. 2019. Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. J Appl Toxicol, doi: 10.1002/jat.3814, open access.

View Abstract

Wikoff D, Erranguntla N, Lewis J, Foreman J. A fit-for-purpose framework for use of systematic methods in risk assessment. Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Urban J, Wikoff D, Haws L. Three-tiered approach to integrating evidence streams assessing gestational trichloroethylene exposure and congenital heart defects (TCE-CHD). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine. Washington, DC, June 2019.

Borghoff S, Fitch S, Britt J, Franke K, Wikoff D. Application of the EFSA/ECHA endocrine disruption guidance as a framework for evidence integration in a weight-of-evidence (WoE) analysis for oxybenzone (BP-3). Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Kreider ML, Hynds ES, Panko JM. Evaluation of tire and road wear particles (TRWP) in air in Delhi, India. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 10–14, 2019.

View Abstract

Heintz MM, Kumar R, Rutledge M, Baldwin WS. 2019. Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis. J Nutr Biochem 70:125–137.

View Abstract

Heintz MM, Kumar R, Baldwin WS. Cyp2b-null male mice are susceptible to high-fat diet-induced obesity due to changes in PUFA metabolism and response to hepatic lipids as measured by RNAseq. International Congress on Toxicology (ICTXV), Honolulu, HI, July 2019.

Olack E, Heintz MM, Baldwin WS. Human CYP2B6 is an anti-obesity enzyme involved in unsaturated fatty acid metabolism. International Congress on Toxicology (ICTXV), Honolulu, HI, July 2019.

Heintz MM, Sengupta N, Noorai R, Baldwin WS. Triclosan exposure represses development and alters sphingomyelin metabolism in Daphnia magna as determined by RNA-seq and lipidomics. 20th Pollutant Responses in Marine Organisms, PRIMO20, Charleston, SC, May 2019.

Heintz MM, McRee R, Baldwin WS. The role of Cyp2b in diet-induced nonalcoholic steatohepatitis. Invited speaker: Clemson University Environmental Toxicology program seminar, Clemson, SC, April 2019.

Rogers JM, Watanabe M. 2019. Special issue on “Developmental effects of smoking, vaping, and cannabis  use” (Introduction). Birth Defects Res 111:1245–1247.

View Abstract

Rogers JM. 2019. Smoking and pregnancy: Epigenetics and the developmental origins of the metabolic syndrome. Special Issue on Smoking, Vaping and Cannabis, Birth Defects Res 111:1259–1269.

View Abstract

Saldanha G, Gulbech Ording A, Bylsma LC, Darvalics B, Tang J, Tof Sorensen H, Fryzek J. Cohort study of high frequency basal cell carcinoma (BCC) patients in Denmark. Poster presented at the Society for Investigative Dermatology, May 2019, Chicago, IL.

Su J, Bylsma LC, Jiang X, Morales Arias J, Jain N, Nordyke RJ. Healthcare resource utilization among commercially insured cold agglutinin disease patients in the United States. Poster presented at the International Society for Pharmacoeconomics and Outcomes Research, May 2019, New Orleans, LA.

Fryzek J, Bylsma LC, Nordyke RJ, Sorensen HT. Rare disease epidemiology: A Danish population-based program. Poster presented at the International Society for Pharmacoepidemiology, August 2019, Philadelphia, PA.

Bylsma LC, Levin-Sparenberg E, Lowe K, Sangare L, Fryzek J, Alexander DD. Prevalence of KRAS, NRAS, and BRAF gene mutations in metastatic colorectal cancer (MCRC) patients: A systematic literature review and meta-analysis. Poster presented as part of a Spotlight Poster Session at the International Society for Pharmacoepidemiology, August 2019, Philadelphia, PA.

Bylsma LC, Dean R, Lowe K, Sangare L, Alexander D, Fryzek J. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis. Poster presented at the International Society for Pharmacoepidemiology, August 2019, Philadelphia, PA.

Bylsma LC, Saldanha G, Gulbech Ording A, Darvalics B, Tang J, Tof Sorensen H, Fryzek J. Cohort study of high frequency basal cell carcinoma (BCC) patients in Denmark. Poster presented at National Organization for Rare Disorders (NORD) Summit, October 2019, Washington, D.C.

Bare JL, Novick RM, Maskrey JR, Unice KM. Screening air dispersion modeling approach: Prop 65 community exposure assessments for industrial emitters. Platform Presentation at Air and Waste Management Association’s (AWMA) Annual Conference and Exhibition: Conference Proceedings, Quebec City, Quebec, June 2019.

Bare JL, Maskrey JR, Hallett LA, Hamaji CM, Unice KM. 2019. Qualitative review of recent USEPA TSCA occupational inhalation exposure assessments: Recommendations for future assessments. Abstract P.122. Poster Presentation at Society for Risk Analysis (SRA) Annual Meeting, Arlington, VA, December 2019.

Scott PK, Abramson MM, Bare JL, Barlow CA. 2019. Air dispersion modeling for historical community exposure reconstruction: An evaluation of the approach and its uncertainties. EM-Mag Environ Mgrs, January

View Abstract

Chamberlain AM, Cohen SS, Weston SA, Fox KM, Xiang P Killian JM Qian Y. 2019. Relation of cardiovascular events and deaths to low-density lipoprotein cholesterol level among statin-treated patients with atherosclerotic cardiovascular disease. Am J Cardiol 123(11):1739-1744.

View Abstract

Sheridan E, Moose J, Liu Y, Martini C, Lea I, Fostel J. NTP high-level summary data collections in the Chemical Effects in Biological Systems (CEBS) database. Presented at the 15th International Congress of Toxicology, Honolulu, HI, July 2019. Poster PS01-0606.

Bhawana B, Lea I, Liu Y, Martini C, Fostel J. Access to National Toxicology Program histopathology lesion collection in Chemical Effects in Biological Systems (CEBS) database. Presented at the 38th Annual Symposium of Society for Toxicologic Pathology, Raleigh, NC, June 2019. Poster P040.

Lea I, Liu Y, Sheridan E, Motti D, Martini C, Fostel J, Auerbach S. Hallmark gene set annotation for NTP toxicogenomic studies. Presented at the 58th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2019. Abstract #1743-P119.

View Abstract

Martini C, Liu Y, Motti D, Johnson J, McCormick K, Lea I, Fostel F. Integrating assay datasets into Chemical Effects in Biological Systems (CEBS). Presented at the 58th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2019. Abstract #1749-P125.

View Abstract

Storm HM, Shepard J, Czerkies LM, Kineman B, Cohen SS, Reichert H, Carvalho R. 2019. 2’-Fucosyllactose is well tolerated in a 100% whey, partially hydrolyzed infant formula with Bifidobacterium lactis: A randomized controlled trial. Global Pediat Health 6:1–10. DOI: 10.1177/2333794X19833995.

View Abstract

Klosterbuer A, Neutel JM, Cohen SS, Periman S. Plasma glucose and insulin response to high protein oral nutritional supplements in adults with type 2 diabetes mellitus. Poster at ASPEN 2019 Nutrition Science & Practice Conference, March 2019, Phoenix, AZ.

View Abstract

Wikoff D. Rigor and resources for systematic reviews in toxicology: Case study applications in food safety, consumer product safety, and environmental health risk assessment. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Gentry R, Greene T, Granzen A, Thompson CM. Formaldehyde and leukemia: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Urban J, Wikoff D, Suh M, Britt J, Harvey S, Chappell G, Haws L. Comparison of NTP OHAT and US EPA TSCA study quality criteria: Trichloroethylene (TCE) and congenital heart defects (CHDs) as a case study. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

McIntyre B, Zorilla L, Borghoff, S, Foster P. Assessment of avobenzone, ensulizole, homosalate, and padimate-O in endocrine disruptor screening panel studies. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Thompson CM, Gentry R. An updated mode-of-action analysis for formaldehyde-induced nasal tumors in rodents: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Borghoff SJ, Fitch S, Huggett, Wikoff D. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA). 2019. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Saili KS, Zurlinden TH, Antonijevic T, Shah I, Deisenroth C, Knudsen TB. Endodermal differentiation trajectories diverge with increasing all-trans retinoic acid (ATRA) exposure. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C. Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Henderson RG, Doepker C, Lopez JG. Safety evaluation of L-theanine administered via hard chew to dogs. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

View Abstract

Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, Ring C, Proctor D. 2019. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Crit Rev Toxicol [ePub ahead of print]: doi: 10.1080/10408444.2019.1578730.

View Abstract

Wikoff D, Fitch SE, Payne L, Doepker C, van de Ligt J. 2019. Systematic map: Use of the acceptable daily intake (ADI) values in nutrition research studies that consider the safety of low-calorie sweeteners. Open Science Framework.

View Abstract

Rager JE, Suh M, Chappell G, Thompson CM, Proctor DM. 2019. Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis. Toxicol Lett 305:40-50.

View Abstract

Wikoff DS, Rager JE, Chappell GA, Fitch S, Haws L, Borghoff SJ. 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335.

View Abstract

Bylsma LC, Reichert H, Gage SM, Roy-Chaudhury P, Nordyke RJ, Fryzek J, Dahl SLM, Lithgow T, Lawson JH. 2019. Clinical outcomes of arteriovenous access in incident hemodialysis patients with Medicare coverage, 2012–2014. Am J Nephrol 49(2):156–164, doi: 10.1159/000495355. Epub Jan 24.

View Abstract

Suh M, Casteel S, Dunsmore M, Ring C, Verwiel A, Proctor DM. 2019. Bioaccessibility and relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Sci Tot Environ 660:677–689.

View Abstract

Mihalchik-Burhans AL, Rogers EN. 2019. Considerations for leachables and extractables testing. In: Gad S (ed), Integrated Safety and Risk Assessment for Medical Devices and Combination Products, pp. 239–263. Springer.

View Abstract

Mihalchik-Burhans AL, Sullivan DW. 2019. Bridging issues of route. In: Gad S (ed), Integrated Safety and Risk Assessment for Medical Devices and Combination Products, pp. 273–297. Springer.

View Abstract

2018

Wikoff D. Problem formulation: Lessons and tools from practical applications involving systematic review of mechanistic data. Presented at Strategies and Tools for Conducting Systematic Reviews of Mechanistic Data to Support Chemical Assessments, National Academies of Sciences, Engineering, and Medicine. Washington, D.C., December 2018.

Urban J, Wikoff D, Haws L, Fitch S, Ring C, Thompson C, Suh M. 2018. Systematic review protocol: Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count. Zenodo. http://doi.org/10.5281/zenodo.1636357.

View Abstract

Kimzey AL, Piche M-S, Wood M, Weir AB, Lansita J. 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3rd Ed. Vol 11:399–427.

View Abstract

Brorby G, Ring C, Loko F, Harris MA. Characterization of hexavalent chromium and total chromium in drinking water monitoring data. Poster MP 117. Society of Environmental Toxicology and Chemistry (SETAC) North America 39th Annual Meeting, Sacramento, CA, November 4–8, 2018.

View Abstract

Tsaioun K, Dirven H, Beck Færden K, Wikoff D, Ram R, Kleinstreuer N, McCormack A, Wright R, Vist GE, Fitch S. 2018. Systematic reviews of the hepatotoxic effects of specified compounds/drugs as observed in humans and experimental animals (rats, mice, dogs and non-human primates). PROSPERO CRD42018112353.

View Abstract

Blanchett A., Grimm FA, Dalaijamts C, Hsieh NH, Ferguson K, Luo YS, Rusyn I, Chiu WA. An in vitro human Bayesian population pharmacodynamic model for predicting effects on heart rhythm. Presented at EPA Organotypic Culture Models STAR center update meeting, May 2018.

Grimm FA, Blanchette A, House JS, Ferguson K, Hsieh N-H, Dalaijamts C, Wright AA, Anson B, Wright FA, Chiu WA, Rusyn I. 2018. A human population-based organotypic in vitro model for cardiotoxicity screening. ALTEX 35(4):441–452, Epub 2018/07/08, doi: 10.14573/altex.1805301. PMID: 29999168.

View Abstract

Suh M, Wikoff D, Harvey S, Mittal L, Lipworth L, Goodman M, Goodmanson A, Ring C, Rohr A, Proctor D. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.

View Abstract

Borghoff SJ, Fitch S, Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99:168–181.

View Abstract

Ring CL, Suh M, Casteel S, Dunsmore M, Verwiel A, Proctor D. Relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.

View Abstract

Hooda N, McFarlane T, Pasetka M, DeAngelis C. 2018. Investigating guideline-consistent anti-emetic prescribing practices at the Odette Cancer Centre (OCC). Poster for oral presentation seminar, “Meet the Future Leaders in Research,” at the Ontario Pharmacist Conference, Huntsville, ON, June 2018.

Harrill AH, Borghoff S, Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ. 2018. NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies. National Toxicology Program Research Report 6, Research Triangle Park, NC.

View Abstract

Chowdhary P, Vivanco SN, Kelly C, Leiga A. What’s in your laundry detergent? An evaluation of common surfactants found in laundry detergents and their PBT characteristics. Presentation to Society of Environmental Toxicology and Chemistry, November 2018.

Vivanco SN, Chowdhary P, Kelly C. Evaluating Prop65 exposure to ethylene oxide and 1,4-dioxane in personal care products. Presentation to Society of Environmental Toxicology and Chemistry, November 2018.

Chesney AR, O’Brien KM, Jordan H, Bakko A, Drey H, Ealy D, Wheiland T, Osinski M. Plethysmography versus blood-gas parameters: Overlap and considerations in nonclinical safety assessment studies. Society of Toxicology, San Antonio, TX, March 2018.

View Abstract

Wikoff DS, Thompson C, Rager J, Chappell G, Fitch S, Doepker C. 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120:709-723.

View Abstract

Ellis ED, Boice JD Jr, Golden AP, Girardi DJ, Cohen SS, Mumma MT, Shore RE, Leggett RW, Kerr GD. 2018. Dosimetry is key to good epidemiology: Workers at Mallinckrodt Chemical Works had seven different source exposures. Health Phys 114(4):386-397.

View Abstract

McMillan DA. Large scale botanical and phytochemical data to assist in rapid analysis for safety assessment. 18th Annual Oxford International Conference on the Science of Botanicals, Oxford, MS, April 2018.

Roe AL, McMillan DA, Mahony C. 2018. A tiered approach for the evaluation of the safety of botanicals used as dietary supplements: An industry strategy. Clin Pharmacol Therapeut 104(3):446–457.

View Abstract

Boice JD Jr, Ellis ED, Golden AP, Girardi DJ, Cohen SS, Chen H, Mumma MT, Shore RE, Leggett RW. 2018. The past informs the future: An overview of the Million Worker Study and the Mallinckrodt Chemical Works cohort. Health Phys 114(4):381-385.

View Abstract

Moffat I, Martinova N, Seidel C, Thompson CM. 2018. Hexavalent chromium in drinking water. Journal AWWA 110:5.

View Abstract

Benson SM, Maskrey JR, Nembhard M, Panko JM. Characterization of surgical smoke generated from electrocautery instruments: A pilot study. Poster at the 2018 American Occupational Health Conference (AOHC) 103rd Annual Meeting, New Orleans, LA, April 29 – May 2, 2018.

Grimm FA, Klaren WD, Li X, House JS, Chiu W, Lehmler HJ, Robertson LW, Rusyn I. Cardiotoxicity screening of polychlorinated biphenyls and their major metabolites. Society of Toxicology Annual Meeting, San Antonio, Tx (presenter), 2018.

View Abstract

Klaren WD, Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams. Society of Toxicology Annual Meeting, San Antonio, Tx, 2018.

View Abstract

Panko J, Kreider M, Unice K. 2018. Review of tire wear emissions. Chapter 7 in: Amato (ed)., Non-Exhaust Emissions — An Urban Air Quality Problem for Public Health; Impact and Mitigation Measures. Elsevier, Amsterdam, Netherlands, pp.147–160.

Cohen SS, Mumma MT, Dupree Ellis E, Boice JD Jr. 2018. Validating the use of census data on education as a measure of socioeconomic status in an occupational cohort. Int J Radiat Biol Nov 19:1–10.

View Abstract

Wikoff D, Goodrum P, Haws L, Budinsky R. Application of quantitative approaches to assess uncertainties in the development of toxicity values: A case study involving the reference dose (RfD) for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.

View Abstract

Urban JD, Harvey S, Haws LC, Wikoff D. Assessment of study quality (risk of bias) in understanding the relationship between congenital heart defects (CHDs) and exposures to trichloroethylene (TCE). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.

View Abstract

Wikoff D. Moving beyond theory to the use of systematic review to support regulatory decision making for evidence-based risk assessment. Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.

View Abstract

Borghoff S, Wikoff D, Urban JD, Rager JE. A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.

View Abstract

Klaren WD, Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342, PMID: 30070899.

View Abstract

Klaren WD, Ring C, Harris MA, Thompson CM, Borghoff S, Sipes NS, Hsieh JH, Auerbach SS, Rager JE. 2018. Identifying attributes that influence in vitro-to-in vivo concordance by comparing Tox21 bioactivity versus DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci 167(1):157–171, PMID: 30202884.

View Abstract

Rish W. Amended TSCA impacts on OSHA: Product stewardship implications. Presented at Product Stewardship 2018 Conference, Washington, DC, September 2018.

Godefroy S, Yeung J, Albornoz G, Almy D, Green AB, Bhandari S, Brown R, Da Costa P, Digonnet V, Doi H, Dubois A, Garber E, Gene T, Gilboa-Geffen A, Goodwin P, Haas-Lauterbach S, Kavolis D, Koerner T, Lacorn M, Lau A, et al. 2018. Standard Method Performance Requirements (SMPRs®) 2018.003: Quantitation of milk by ELISA-based methods. J AOAC Int 101(4):1276–1278, doi: 10.5740/jaoacint.SMPR2018.003.

View Abstract

Godefroy S, Yeung J, Albornoz G, Almy D, Green AB, Bhandari S, Brown R, Da Costa P, Digonnet V, Doi H, Garber E, Gene T, Gilboa-Geffen A, Goodwin P, Haas-Lauterbach S, Kavolis D, Koerner T, Lacorn M, Lau A, et al. 2018. Standard Method Performance Requirements (SMPRs®) 2017.020: Quantitation of chicken egg by ELISA-based methods. J AOAC Int 101(4):1236–1237, doi: 10.5740/jaoacint.SMPR2017.020.

View Abstract

Heintz MM, Kumar R, Baldwin WS. Cyp2b-null male mice are susceptible to high-fat diet-induced obesity due to changes in PUFA metabolism and response to hepatic lipids as measured by RNAseq. American College of Toxicology, 39th Annual Meeting, West Palm Beach, FL, November 2018.

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells. Annual Biomedical Research Conference for Minority Students (ABRCMS), Indianapolis, IN, November 2018.

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells.  Research Experiences for Undergraduates (REUs), Alexandria, VA, October 2018.

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells. Clemson Summer Research Symposium, July 2018.

Heintz MM, Kumar R, Baldwin WS. The role of Cyp2b in the metabolism of unsaturated fatty acids. Abstract #1291, Society of Toxicology meeting, San Antonio, TX, March 2018.

View Abstract

McRee R, Heintz MM, Baldwin WS. Inhibition of CYP2B6 does not necessarily alter toxicity except in the case of chemicals with known active metabolites. Abstract #1292, Society of Toxicology meeting, San Antonio, TX, March 2018.

View Abstract

Wikoff DS, Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337.

View Abstract

Kempisty DM, Xing Y, Racz L (eds). 2018. Perfluoroalkyl Substances in the Environment: Theory, Practice and Innovation. Taylor and Francis CRC Press, Boca Raton, FL.

View Abstract

Ruzin A, Pastula ST, Levin-Sparenberg EM, Jiang X, Fryzek JP, Tovchigrechko A, Lu B, Qi Y, Liu H, Jin H, Yu L, Hackett J, Villafana T, Esser MT. 2018. Characterization of circulating RSV strains among subjects in the OUTSMART-RSV surveillance program during the 2016-17 winter viral season in the United States. PLoS One 13(7):e0200319.

View Abstract

Garabrant DH, Pastula ST. 2018. A comparison of asbestos fiber potency and elongate mineral particle (EMP) potency for mesothelioma in humans. Toxicol Appl Pharmacol 361:127–136.

View Abstract

Bare JL, Abramson MM, Maskrey JR, Manning CM, Keenan JJ. 2018. Proposition 65 risk assessment model framework for chemically-complex consumer products. Abstract #3525. Poster Presentation at Society of Toxicology (SOT) Annual Meeting, San Antonio, TX, March 2018.

View Abstract

McMenamy C, Jacobs N, Bare JL, Keenan JJ. 2018. Potential exposure to hydrogen fluoride from a thermal runaway event in an airplane cockpit. Abstract #653. Poster Presentation at American Industrial Hygiene Conference & Exposition (AIHce), Philadelphia, PA, May 2018.

Abramson MM, Bare JL, Barlow CA, Scott PK. 2018. Evaluation of the uncertainties associated with the use of air dispersion modeling to estimate historical community exposure from manufacturers of asbestos-containing products. Platform Presentation at Air and Waste Management Association’s (AWMA) Annual Conference and Exhibition: Conference Proceedings, Hartford, CT, June 2018.

Mihalchik AL, Rogers EN, Gad-McDonald SE, Sullivan DW Jr, Gad SC. Development of dermal permissible daily exposure (PDE) levels for elemental impurities by utilizing data from alternative routes. Poster presented at the Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Mihalchik-Burhans A. And you want this by when? Making the successful transition from the bench to consulting. Oral presentation at the American College of Toxicology 39th Annual Meeting, West Palm Beach, FL, November 2018.

Thompson CM, Wolf JC, Suh M, Proctor DM, HJaws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018.

View Abstract

Thompson CM, Suh M, Proctor DM, Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018.

View Abstract

Proctor, DM. Updating the regulatory risk assessment for hexavalent chromium in California: Implications for regulatory standards. Association of Environmental Health Sciences San Diego, CA, March 20, 2018.

Thompson CT, Suh M, Chappell G, Borghoff S, Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor, DM. 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189 doi: 10.1016/j.yrtph.2018.05.006.

Suh M, Proctor DM, Chappell G, Rager JE, Thompson CM, Borghoff S, Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicology 402-403:50-67, doi: 10.1016/j.tox.2018.04.006.

View Abstract

Proctor DM, Suh M, Chappell G, Borghoff SJ, Thompson CM, Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol, 96:30-40, doi: 10.1016/j.yrtph.2018.04.016.

View Abstract

Mumma MT, Cohen SS, Sirko JL, Ellis ED, Boice JD Jr. 2018. Obtaining vital status and cause of death on a million persons. Int J Radiat Biol 9:1–21.

View Abstract

Golden AP, Cohen SS, Chen H, Ellis ED, Boice JD Jr. 2018. Evaluation of statistical modeling approaches for epidemiologic studies of low dose radiation health effects. Int J Radiat Biol Nov 30:1–2.

View Abstract

Proctor DM. Hexavalent chromium in drinking water: When is the science sufficient to deviate from defaults? Invited Speaker, Genetic and Environmental Toxicology Association (GETA).  Thresholds in Toxicology and Risk Assessment Fall Symposium.  Oakland, CA, November 14, 2018.

Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I, Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Presented at the 57th Annual Meeting of Society of Toxicology, San Antonio, TX, March 2018. Abstract 2525-P887.

View Abstract

Lea IA, Borghoff S, Travlos GS. 2018. Electrolytes, blood gases and acid-base balance. In: Kurtz DM, Travlos GS (eds): The Clinical Chemistry of Laboratory Animals (3rd edition). CRC Press, Boca Raton, FL (https://doi.org/10.1201/9781315155807).

Brorby GP. 2018. The ongoing controversy surrounding the effects of short-term exposure to trichloroethene. Presented at the Association for Environmental Health and Sciences Foundation Annual International Conference, March 19–22, San Diego, CA.

Thompson CM, Kirman CR, Hays SM, Suh M, Harvey SE, Proctor DM, Rager JE, Haws LC, Harris MA. 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545.

View Abstract

Verougstraete V, Henderson R, Mackie C, Newson T, Oller A. 2018. Human health (toxicity) assessment of complex inorganic materials. In: Verougstraete V (ed), Risk Management of Complex Inorganic Materials. Elsevier Inc. ISBN 978-0-12-811063-8.

View Abstract

Wikoff D, Urban JD, Harvey S, Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol, DOI: 0.1177/1091581818754330.

View Abstract

Mihalchik AL, Rogers EN. 2018. Classes of compounds with GI tract toxicity. Chapter 13 in: Gad SC (ed), Toxicology of the Gastrointestinal Tract. CRC Press.

View Abstract

Doepker C, Franke K, Myers E, Goldberger JJ, Lieberman HR, O’Brien C, Peck J, Tenenbein M, Weaver C, Wikoff D. 2018. Key findings and implications of a recent systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Nutrients 10:1536, doi: 10.3390/nu10101536.

View Abstract

Rish W, Pfau EJ. 2018. Bounding analysis of drinking water health risks from a spill of hydraulic fracturing flowback water. Risk Analysis 38(4):724-754, DOI: 10.1111/risa.12884.

View Abstract

2017

Lansita J,  Mease KM, Qiu H, Yednock T, Sankaranarayanan S, Kramer S. 2017. Nonclinical development of ANX005: A humanized anti-Clq antibody for treatment of autoimmune and neurodegenerative diseases. Int J Toxicol 1-14. DOI: 10.1177/1091581817740873.

View Abstract

Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C, Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; DOI: 10.1021/acs.chemrestox.7b00221.

View Abstract

Thompson CM, Suh M, Proctor DM, Haws LC, Harris MA. 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutation Res 823:45-57.

View Abstract

McMillan DA, Kosemund K, Mahony C, Huber M, Bowtell P. Threshold of toxicological concern (TTC) for botanicals—Data analysis to substantiate and extend the TTC approach to botanicals. In: The Toxicologist: Suppl to Toxicol Sci 156(1), Abstract no. 1831, Society of Toxicology, 2017.

View Abstract

Thompson CM, Young RR, Dinesdurage H, Suh M, Harris MA, Rohr AC, Proctor DM. 2017. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of Big Blue® rats. Toxicol Appl Pharmacol 330(1):48-52.

View Abstract

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB Is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology Annual Meeting, Baltimore, Md, and NIEHS Environmental Health Science FEST, Durham, NC, 2017.

View Abstract

Iwata Y, Klaren W, Grimm F, Rusyn I. A multidimensional high-throughput approach for toxicity evaluation of environmental chemicals in induced pluripotent stem cell-derived endothelial cells. Society of Toxicology Annual Meeting, Baltimore, Md, 2017.

View Abstract

Iwata Y, Klaren WD, Lebakken CS, Grimm FA, Rusyn I. 2017. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay Drug Dev Technol 15(6):267–279, PMID: 28771372.

View Abstract

Ruzin A, Levin-Sparenberg E, Pastula S, Jiang X, Fryzek J, Tovchigrechko A, Lu B, Yu L, Hackett J, Villafana T, Esser MT. Characterization of RSV strains among U.S. patients in the OUTSMART RSV program during 2015-16. Abstract, poster presentation, ID Week 2017, San Diego, CA, October 2017.

Garabrant D, Pastula S. Asbestos and EMP fiber potency analysis. Abstract, Oral Presentation, Monticello Conference, Charlottesville, VA, October 2017.

Wikoff DS, Rager JE, Harvey S, Haws LChappell G, Borghoff S. Development and refinement of a framework for quantitative consideration of study quality and relevance in the evaluation of mechanistic data based on Key Characteristics of Carcinogens. Society of Risk Analysis Annual Meeting. December 10-14, 2017. Arlington, VA.

View Abstract

Wikoff DS, Welsh BT, Henderson R, Brorby G, Britt J, Myers E, Goldberger J, Lieberman HR, O’Brien C, Doepker C. Application of systematic reviews in the evaluation of caffeine safety: Potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Society of Risk Analysis Annual Meeting. December 10-14, 2017. Arlington, VA.

View Abstract

Klaren WD, Vine D, Vogt S, Robertson LW. 2017. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433, PMID: 28940161.

View Abstract

Panko J, Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. A comparative evaluation of five hazard screening tools. Integr Environ Assess Manag 13(1):139–154.

See also: Panko J, Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. Letter to the Editor: Authors’ response to Turner et al. Integr Environ Assess Manag 13(1):15–16.

View Abstract

Perez AL, Gauthier AM, Ferracini T, Cowan DM, Kingsbury T, Panko J. 2017. The challenge of predicting problematic chemicals using a decision analysis tool: Triclosan as a case study. Integr Environ Assess Manag 13(1):198–207.

View Abstract

Burns A, Shin J, Unice KM, Gaffney SH, Kreider ML, Gelatt RN, Panko JM. 2017. Combined analysis of job and task benzene air exposures among workers at four US refinery operations. Toxicol Indust Health 33(3):193–210.

View Abstract

Rish W. Bounding analysis of drinking water health risks from a spill of hydraulic fracturing flowback water. Presented at the Marcellus Shale Coalition Member Meeting, Pittsburgh, PA, January 2017.

Chappell GA, Rager JE. 2017. Epigenetics in chemical-induced genotoxic carcinogenesis. Current Opinion Toxicol 6:10-17.

View Abstract

Pastula ST, Hackett J, Coalson J, Jiang X, Villafana T, Fryzek J. 2017. Hospitalizations for respiratory syncytial virus disease among adults in the United States, 1997 to 2012. Open Forum Infect Dis 4(1):ofw270.

View Abstract

Bichteler A, Wikoff DS, Loko F, Harris MA. 2017. Estimating serum concentrations of dioxin-like compounds in the U.S. population effective 2005-2006 and 2007-2008: A multiple imputation and trending approach incorporating NHANES pooled sample data. Environ Int 105(2017):112-125.

View Abstract

Hoffmann S, de Vries RB, Stephens ML, Beck NB, Dirven HAAM, Fowle III JR, Goodman JE, Hartung T, Kimber I, Lalu MM, Thayer K, Whaley P, Wikoff D, Tsaioun K. 2017. A primer on systematic reviews in toxicology. Arch Toxicol DOI: 10.1007/s00204-017-1980-3.

View Abstract

Keenan JJ, Bare JL, McMenamy C, Chapman A, Miller E. 2017. Screening-level risk assessment of hydrogen fluoride exposure resulting from a thermal runaway event on an aircraft. Abstract #2829. Poster Presentation at Society of Toxicology (SOT) Annual Meeting, Baltimore, MD, March 2017.

View Abstract

Hollins DM, Scott PK, Bare JL, Barlow CA, Nembhard M, Maskrey JR, Paustenbach DJ. 2017. Estimating asbestos emissions from former industrial sites and estimating resulting airborne concentrations in the surrounding community: A review of methodologies. Abstract #3248. Poster Presentation at Society of Toxicology (SOT) Annual Meeting, Baltimore, MD, March 2017.

View Abstract

Jacobs N, Bare JL, McMenamy C, Keenan JJ. 2017. Potential chemical exposures following thermal runaway in a lithium ion battery. Abstract #614. Poster Presentation at American Industrial Hygiene Conference & Exposition (AIHce), Seattle, WA, June 2017.

Bare JL, Abramson MM, Barlow CA, Scott PK. 2017. Use of air dispersion modeling to estimate historical community exposure from manufacturers of asbestos-containing products. Abstract P.96. Poster Presentation at Society for Risk Analysis (SRA) Annual Meeting, Arlington, VA, December 2017.

Drechsel DA, Barlow CA, Bare JL, Jacobs NF, Henshaw JL. 2017. Historical evolution of regulatory standards for occupational exposures to industrial talc. Regul Toxicol Pharmacol 91:251–267.

View Abstract

Rager JE, Ring CL, Fry RC, Suh M, Proctor DM, Haws L, Harris MA, Thompson CM. 2017. High-throughput screening data interpretation in the context of in vivo transcriptomic responses to oral Cr(VI) exposure. Toxicol Sci 158(1):199–212. https://doi.org/10.1093/toxsci/kfx085

View Abstract

Wikoff D, Welsh BT, Henderson R, Brorby GP, Britt J, Myers E, Goldberger J, Lieberman HR, O’Brian C, Peck J, Tenebein M, Weaver C, Harvey S, Urban J, Doepker C. 2017. Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Food Chem Toxicol 109(Pt1):585-648. https://doi.org/10.1016/j.fct.2017.04.002.

View Abstract

Greene T, Rogers S, Franzen A, Gentry R. 2017. A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. Crit Rev Toxicol 47(2):98–120. DOI:10.1080/10408444.2016.1236071.

View Abstract

Franzen A, Greene T, Van Landingham C, Gentry R. 2017. Toxicology of octamethylcyclotetrasiloxane (D4). Toxicol Lett 279 Suppl 1:2–22. DOI:10.1016/j.toxlet.2017.06.007.

View Abstract

Gentry R, Franzen A, Van Landingham C, Greene T, Plotzke K. 2017. A global human health risk assessment for octamethylcyclotetrasiloxane (D4). Regul Toxicol Pharmacol 74(Suppl):S25–S43.

View Abstract

Lea I, Yang L, Rashid A, Fostel JM. Chemical Effects in Biological Systems (CEBS) Database: Treatment-related findings. Presented at the 56th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2017. Abstract 2918-P412.

View Abstract

Martini C, Rashid A, Paleja A, Lea I, Fostel JM. Chemical Effects in Biological Systems (CEBS) database: Treatment-related findings. Presented at the 56th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2017. Abstract 1381-P119.

View Abstract

Sheridan E, Martini C, Shaw M, Shockley K, Brix A, Rashid A, Lea I, Fostel J. Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions. Presented at the 36th Annual Symposium of Society for Toxicologic Pathology, Montreal, Quebec, Canada, June 2017. Poster P035.

Jackson M, Yang L, Yauk CL, Lea I, Kuo B, Williams A, Rashid A, Fostel J. The TGx-28.65 biomarker — A web-based application using transcriptomics to identify DNA damage-inducing chemicals. Presented at the 48th Annual Meeting of Environmental Mutagenesis and Genomics Society, Raleigh, NC, September 2017. Abstract 1224.

Kirman CR, Suh M, Proctor DM, Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325:9-17.

View Abstract

Wikoff DS, Rager J, Harvey S, Haws L, Chappell G, Borghoff S. 2017. Framework for quantitative consideration of study quality and relevance in the systematic evaluation of mechanistic data per the Ten Key Characteristics of Carcinogens. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

View Abstract

Jackson MA, Yang L, Lea I, Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535.

View Abstract

Mease K, Kimzey A, Lansita J. 2017. Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design. Curr Opin Toxicol (4:1–15).

View Abstract

Lea IA, Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971.

View Abstract

Doepker D, Tyndall K, Lane R, Wikoff D, Thompson C, Harvey S, Schmitt D. 2017. A proposed ADI for nitrate. Poster presented at Society of Toxicology Annual Meeting, March 16, Baltimore, MD.

View Abstract

Borghoff SJ, Ring C, Banton MI, Leavens TL. 2017. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to ?2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology Annual Meeting, March 16, Baltimore, MD.

View Abstract

Thompson C, Rager J, Suh M, Proctor D, Haws L, Harris M. 2017. Mechanistic support for nonlinear risk assessment of rat oral cavity tumors induced by exposure to Cr(VI) in drinking water. Poster presented at Society of Toxicology Annual Meeting. March 15, Baltimore, MD.

View Abstract

Chappell G, Welsh B, Harvey S, Harris M, Wikoff D. 2017. Validation and application of a text mining tool in the identification and categorization of mechanistic data: A case study in improving problem formulation of carcinogenicity assessments. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

View Abstract

Proctor DM, Suh M, Dunsmore D, Verwiel A, Casteel S. 2017. Bioaccessibility and relative oral bioavailability of cobalt and nickel from metal alloys in soil and dust. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

View Abstract

Kirman CR, Proctor D, Suh M, Haws L, Harris M, Thompson C, Hays S. 2017. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

View Abstract

Rager JE, Thompson CM, Ring C, Fry RC, Harris MA. 2017. Integration of transcriptomics and high-throughput screening predictions with robust in vivo data to inform hexavalent chromium mode of action. Poster presented at Society of Toxicology Annual Meeting, March 14, Baltimore, MD.

View Abstract

Thompson C, Kirman C, Suh M, Proctor D, Haws L, Harris M, Hays S. 2017. Risk assessment of oral exposure to Cr(VI): Integration of mode of action, pharmacokinetics, and dose-response modeling. Poster presented at Society of Toxicology Annual Meeting, March 14, Baltimore, MD.

View Abstract

Mease K, Kimzey A, Lansita J. 2017. Failed dose formulation analysis during a GLP study — Now what? Poster presented at Society of Toxicology Annual Meeting, March 14, Baltimore, MD.

View Abstract

Suh M, Harvey S, Wikoff D, Mittal L, Ring C, Goodmanson A, Proctor D. 2017. Meta-analysis of hexavalent chromium and stomach cancer. Poster presented at Society of Toxicology Annual Meeting, March 13, Baltimore, MD.

View Abstract

Thompson CM, Wolf, JC, McCoy A, Suh M, Proctor DM, Kirman CR, Haws LC, Harris MA. 2017. Comparison of toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens captan, folpet, and hexavalent chromium. Toxicol Pathol 45(8):1091–1101. DOI: 10.1177/019262331yy4324.

View Abstract

2016

Thompson CM, Bichteler A, Rager JE, Suh M, Proctor DM, Haws LC, Harris MA. 2016. Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium. Mut Res/Genetic Toxicol Environ Mutagen 800-801:28-34.

View Abstract

Wikoff D, Suh M, Harvey S, Proctor D, Beretvas T, Goodman M, Lipworth L. 2016. Systematic review and meta-analysis of occupational exposure to Cr(VI) and stomach cancer. PROSPERO 2016:CRD42016051625 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016051625

Thompson CM, Rager JE, Suh M, Ring CL, Proctor DM, Haws LC, Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57:706-716.

View Abstract

De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M, Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid.  I. Chemical reduction and mitigation of mutagenicity. Toxicol Appl Pharmacol   306:113-119.

View Abstract

Rager J, Thompson C, Auerbach S, Fry R. 2016. Integrating genomic and epigenomic data into risk assessment applications through dose response modeling: Case study with prenatal arsenic exposure. Environmental Mutagenesis and Genomics Society, September 25, Kansas City, KS. 

View Abstract

Borghoff SJ, Ring C, Banton M, Leavens TL. 2016. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes.  J Appl Toxicol, DOI 10.1002/jat.3412

View Abstract

Ulrich, K. Adversity and risk assessment of respiratory tract findings — A regulatory perspective. Presentation to the 31st Annual Meeting of the British Society of Toxicological Pathology (BSTP) — Association of Inhalation Toxicologists Joint Conference, Alderley Edge, Cheshire, UK, 2016.

Mackay CE, Vivanco SN, Yeboah G, Vercellone J. 2016. Assessment of dermal hazard from acid burns with fire retardant garments in a full-size simulation of an engulfment flash fire. Burns 42(6):1350–1356.

View Abstract

Williams K, Chesney AR. Proper study design and protocol for preclinical trials. Institute of Food Technologies Annual Meeting, Chicago, IL, July 19, 2016.

Chesney AR, Mancl B, Smith J, Quarberg L, Schroeder M. AlphaTRAK and ReliOn® Confirm glucometers for use in nonclinical laboratory testing; Anticoagulant use and sample site analysis. American College of Toxicology, Baltimore, MD, November 2016.

Chesney AR, Booth CJ, Lietz CB, Li L, Pedersen JA. 2016. Rapid inactivation of disease-associated prion protein by peroxymonosulfate. Environ Sci Technol 50(13):7095–7105.

View Abstract

Wikoff D, Borghoff S, Rager J, Harvey S, Haws L. 2016. A systematic review of the mechanistic evidence of tetrabromobisphenol TBBPA as a human carcinogen according to the ten key characteristics of carcinogens (TKCC) identified by Smith et al. (2016). PROSPERO 2016:CRD42016046429 Available from:  http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016046429

Strittholt CA, McMillan DA, He T, Baker RA, Barker ML. 2016. A randomized clinical study to assess ingestion of dentifrice by children. Regul Toxicol Pharmacol 75:66–71.

View Abstract

Haws L. 2016. Vapor intrusion – Solid ground or quick sand? Invited Speaker. Presented at the 28th Annual Texas Environmental Superconference, August 5, Austin, TX.

Haws L. 2016. Vapor intrusion – Technical issues. Invited Speaker. Presented at the Semi-Annual South Central Regional Meeting of the Auditing Roundtable, August 3, Austin, TX.

Thompson CM, Suh M, Mittal L, Wikoff D, Welsh B, Proctor DM. 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80:60-70.

View Abstract

Klaren WD, Vine D, Vogt S, Robertson LW. Evaluation of the spatial distribution of hepatic metals following PCB126 exposure with x-ray fluorescence microscopy. Society of Toxicology Annual Meeting, New Orleans, La, 2016.

View Abstract

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB Is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Society of Toxicology, Central States Regional Meeting, Iowa City, IA, 2016. Also presented at NIEHS obesity grantee meeting and 25 years of endocrine disruption: Workshop. NIH, Bethesda, Md, 2016.

Klaren WD, Iwata Y, Lebakken CS, Grimm FA, Rusyn I. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. College of Veterinary Medicine Graduate Student and Postdoc Research Symposium, Texas A&M University, 2016.

Borghoff SJ. 2016. Organization and review of mechanistic data according to “Ten Key Characteristics of Carcinogens” (TKCC) {Smith et al., 2016}. Presented at the 42nd Annual Summer Meeting of the Toxicology Forum, July, Salt Lake City, UT.

Panko JM, Benson SM, Kreider ML. Meta-analysis of lung cancer risk related to diesel exposure by occupation and evaluation of exposure response. Abstract #2976. Poster at Society of Toxicology Annual Meeting, New Orleans,LA, March 13–17, 2016.

View Abstract

Gloekler L, Shay EC, Schmidt N, Haghighat B, Panko JM, Cowan DM, Paustenbach DJ. Flame-retardants in upholstered furnishings: An assessment of health risk and fire-related deaths in the era of California Technical Bulletin (TB-117). Abstract #2669. Poster at Society of Toxicology Annual Meeting, New Orleans, LA, March 13–17, 2016.

View Abstract

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB Is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Chem Res Toxicol 29(9):1504–1509. DOI: 10.1021/acs.chemrestox.6b00172.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. 2016. PCB126-induced disruption of gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Toxicol Sci 149(1):98–110, PMID: 26393156.

View Abstract

Wang BW, Klaren WD, Wels B, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G. 2016. Dietary manganese modulates PCB126 toxicity, metal status and MnSOD in the rat. Toxicol Sci 150(1):15–26, PMID: 26660635.

View Abstract

Klaren WD, Flor SS, Gibson-Corley KN, Ludewig G, Robertson LW. 2016. Metallothionein’s role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption. Toxicol Rep 3:21–28, PMID: 26770886.

View Abstract

Klaren WD, Gibson-Corley KN, Wels B, Simmons DL, McCormick ML, Spitz DR, Robertson LW. 2016. Assessment of the mitigative capacity of dietary zinc on PCB126 hepatotoxicity and the contribution of zinc to toxicity. Chem Res Toxicol 29(5):851–859, PMID: 26967026.

View Abstract

Pastula S, Hackett J, Coalson J, Jiang X, Villafana T, Fryzek J. Burden of respiratory syncytial virus disease among adults in the United States from 1997 to 2012. Abstract, poster presentation, International Society for Pharmacoeconomics (ISPOR), Washington, D.C., May 2016.

Pastula S, Hackett J, Coalson J, Jiang X, Villafana T, Fryzek J. Burden of respiratory syncytial virus disease among adults in the United States from 1997 to 2012. Abstract, poster presentation, International Society for Influenza and Other Respiratory Virus Diseases (ISIRV) 2016 — Options IX for the Control of Influenza, Chicago, IL, August 2016.

Pastula S, Hackett J, Coalson J, Jiang X, Villafana T, Fryzek J. Burden of respiratory syncytial virus disease among adults in the United States from 1997 to 2012. Abstract, poster presentation, ID Week 2016, New Orleans, LA, October 2016.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB Is a key event in the dysregulation of gluconeogenesis, glycogenolysis and fatty acid oxidation in PCB126 hepatotoxicity. Chem Res Toxicol 29(9):1504–1509. DOI: 10.1021/acs.chemrestox.6b00172.

View Abstract

Maskrey JR, Insley A, Hynds ES, Panko JM. 2016. Air monitoring of volatile organic compounds at relevant receptors during hydraulic fracturing operations in Washington County, Pennsylvania. Environ Monit Assess 188(7):1–12, Article 410.

View Abstract

Rish W. Addressing the challenges of environmental risk communication. Presented at the Ohio State Bar Association Annual Environmental Conference, April 2016.

Rish W. Adaptive management of remediation. Detroit Remediation Conference, Detroit, Michigan, September 2016.

Rish W. New technology for measuring real-time mass emission rates of methane and VOCs from oil and gas facilities. Presented at Innovative Environmental Monitoring Technology Symposium 2016, Ohio University, October 18, 2016.

Lau A. 2016. Allergen preventive controls. Chapter 4 in: Industry Handbook for Safe Processing of Nuts. Grocery Manufacturers Association and Peanut and Tree Nut Processors Association.

View Abstract

Suh M, Thompson CM, Brorby GP, Mittal L, Proctor DM. 2016. Inhalation cancer risk assessment of cobalt metal. Regul Toxicol Pharm 79(2016):74-82.

View Abstract

Pierce JS, Abelmann A, Ruestow PS, Lotter J, Beckett E, Fritz HA, Bare JL, Unice KM. 2016. Assessment of indoor formaldehyde concentrations following the installation and removal of laminate flooring. Abstract #1689. Poster Presentation at Society of Toxicology (SOT) Annual Meeting, New Orleans, LA, March 2016.

View Abstract

Ruestow PS, Unice KM, Lotter J, Abelmann A, Fritz HA, Beckett E, Bare JL, Pierce JS. 2016. Time trends in formaldehyde emissions from laminate flooring products after installation. Poster Presentation at American Industrial Hygiene Conference & Exposition (AIHce), Baltimore, MD, May 2016.

Pierce JS, Abelmann A, Ruestow P, Lotter J, Beckett E, Fritz HA, Bare JL, Unice KM. 2016. Assessment of indoor formaldehyde concentrations following the installation and removal of laminate flooring. Poster Presentation at American Industrial Hygiene Conference & Exposition (AIHce), Baltimore, MD, May 2016.

Fritz HA, Lotter J, Abelmann A, Ruestow PS, Beckett E, Unice KM, Bare JL, Pierce JS. 2016. Evaluation of diurnal variations in formaldehyde concentrations following installation of laminate flooring using real-time sampling. Poster Presentation at American Industrial Hygiene Conference & Exposition (AIHce) Baltimore, MD, May 2016.

Lotter J, Unice KM, Ruestow PS, Abelmann A, Fritz HA, Beckett E, Bare JL, Pierce JS. 2016. Formaldehyde emissions from small chamber testing of laminate flooring and comparison to exposure modeling. Podium Presentation at American Industrial Hygiene Conference & Exposition (AIHce), Baltimore, MD, May 2016.

Paustenbach DJ, Insley AL, Maskrey JR, Bare JL, Unice KM, Conrad VB, Iordanidis L, Reynolds DW, DiNatale KD, Monnot AD. 2016. Analysis of total arsenic content in California wines and comparison to various health risk criteria. Am J Enol Viticult 67(2):179–187.

Pierce JS, Abelmann A, Lotter JT, Ruestow PS, Unice KM, Beckett EM, Fritz HA, Bare JL, Finley BL. 2016. An assessment of formaldehyde emissions from laminate flooring manufactured in China. Regul Toxicol Pharmacol 81:20–32.

View Abstract

Kirman CR, Suh M, Hays SM, Gürleyük H, Gerads R, De Flora S, Parker W, Lin S, Haws LC, Harris MA, Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid.  II. Ex vivo gastric reduction modeling. Toxicol Appl Pharmacol 306:120-133.

View Abstract

Franzen A, Van Landingham C, Greene T, Plotzke K, Gentry R. 2016. A global human health risk assessment for decamethylcyclopentasiloxane (D5). Regul Toxicol Pharmacol 74:25–43.

View Abstract

Campbell J, Franzen A, Van Landingham C, Lumpkin M, Crowell S, Meredith C, Loccisano A, Gentry R, Clewell H. 2016. Predicting lung dosimetry of inhaled particle-borne benzo(a)pyrene using physiologically based pharmacokinetic modeling. Inhal Toxicol 28(11):520–535.

View Abstract

Haws L. 2016. Trichlorethylene exposure and development of fetal cardiac malformations: What do the data tell us about inhalation exposures resulting from vapor intrusion and potential health risks to pregnant women? – Introduction. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Proctor DM. 2016. Cancer risk assessment for ingested hexavalent chromium:  Challenges and controversies – Introduction. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA [session introduction; no abstract].

Wikoff D, Borghoff SJ, Rager JE, Haws LC. 2016. Human relevance assessment of tetrabromobisphenol-A (TBBPA) induced uterine adenocarcinomas: Mode of action dependent on high dose molecular initiating event (MIE). Presented in the “Flame Retardants” session at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Suh M. 2016. Cumulative risk assessment of urban air toxics: A pilot study in San Antonio, Texas. Presented in the “Quantitative Cumulative Risk Assessment: Is it Feasible Today?” Session of the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Thompson CM. 2016. Non-mutagenic MOA for Cr(VI) involving intestinal cytotoxicity and regenerative hyperplasia. Platform presentation in the “The Cancer Risk Assessment for Ingested Hexavalent Chromium: Challenges and Controversies” Session. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Borghoff SJ,  Wikoff D, Rager JE, Haws LC. 2016. Tetrabromobisphenol A (TBBPA); Dose- and time-dependent changes in plasma TBBPA and its conjugates over 28 days of administration. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, 2016. New Orleans, LA.

View Abstract

DeVito MJ, Borghoff SJ, Zorilla LM, Shockley K, Kissling G,  Travlos G. 2016. The effects of a high fat (HF) diet on male diversity outbred (DO) mice. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Cullen JM, Ward JM, Thompson CM. 2016. Re-evaluation and classification of duodenal lesions in B6C3F1 mice and F344 rats from four studies of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Thompson CM, Suh M, Proctor DM, Rager JE, Haws LC, and Harris MA. 2016. Assessment of the in vivo genotoxicity of CrVI in target organs identified in a two-year cancer bioassay. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Suh M, Crump K, Mittal L, Hirsch S, Valdes Salgado R, BartlettC, Van Landingham C, Rohr A, Proctor DM. 2016. Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Brorby GP, Suh M, Thompson CM, Mittal L, Proctor DM. 2016. Inhalation cancer risk assessment of cobalt metal. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

View Abstract

Verwiel A, Proctor D, Tachovsky A. 2016. Principal component analysis of metals in soil and dust to distinguish background and anthropogenic sources in an urban area. Association for Environmental Health and Sciences Foundation Annual Meeting, March 14, San Diego, CA.

View Abstract

Cullen JM, Ward JM, Thompson CM. 2016. Reevaluation and classification of duodenal lesions in B6C3F1 mice and F344 rats from 4 studies of hexavalent chromium in drinking water. Toxicologic Pathol 44(2):279-89.

View Abstract

Wikoff DS, Britt JK.  2016. The role of systematic review in the practice of toxicology and risk assessment – An appreciation for the primary tool in evidence-based approaches.  Toxicology: Open Access 2(110):1-4. 

View Abstract

Wikoff DS, Rager JE, Haws LC, Borghoff SJ. 2016. A high dose mode of action for tetrabromobisphenol A-induced uterine adenocarcinomas in Wistar Han rats: A critical evaluation of key events in an adverse outcome pathway framework. Regul Toxicol Pharmacol 77:143-159. doi: 10.1016/j.yrtph.2016.01.018

View Abstract

Hanlon P, Brorby GP, Krishan M. 2016. A risk-based strategy for evaluating mitigation options for processed-formed compounds in food: Workshop proceedings. Int J Toxicol 35(3):358–370.

View Abstract

Schmitt D, Levy R, Carroll B. 2016. Toxicological evaluation of ß-caryophyllene oil: Subchronic toxicity in rats. Int J Toxicol 35(5):558–567.

View Abstract

Borghoff SJ, Wikoff D, Harvey S, Haws L. 2016. Dose- and time-dependent changes in tissue levels of tetrabromobisphenol A (TBBPA) and its sulfate and glucuronide conjugates following repeated administration to female Wistar Han Rats. Toxicol Rep 3:190-201. doi:10.1016/j.toxrep.2016.01.007

View Abstract

Doepker C, Lieberman HR, Smith AP, Peck JD, El-Sohemy A, Welsh BT. 2016. Caffeine: Friend or Foe? Annu Rev Food Sci Technol. DOI: 10.1146/annurev-food-041715-033243

View Abstract

Sisler JD, Li R, McKinney W, Mercer RR, Ji Z, Xia T, Wang X, Shaffer J, Orandle M, Mihalchik AL, Battelli L. 2016. Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice. Particle Fibre Toxicol 13(1):42.

View Abstract

Sisler JD, Pirela SV, Shaffer J, Mihalchik AL, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, Demokritou P, Qian Y. 2016. Toxicological assessment of CoO and La2O3 metal oxide nanoparticles in human small airway epithelial cells. Toxicol Sci 13(1):42.

View Abstract

2015

Proctor DM, Suh M, Mittal L, Hirsch S, Salgado RV, Bartlett C, Van Landingham C, Rohr A, Crump K. 2015. Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. J Expo Sci Environ Epidemiol 26(2):224-231. doi: 10.1038/jes.2015.77.

View Abstract

James RC, Britt JK, Halmes NC, Guzelian PS. 2015. Evidence-based causation in toxicology: A 10-year retrospective. Hum Exp Toxicol 34(12):1245–1252.

View Abstract

Wikoff D, Doepker C, Welsh B, Urban J, Henderson R, Britt J, Harvey S, Goldberger J, Myers E, O’Brien C, Peck J, Lieberman H, Weaver C, Tenebein M. 2015. Systematic review of the adverse bone and calcium balance effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026609 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015026609 (Systematic Review Protocol Registration)

Wikoff D, Doepker C, Welsh B, Urban J, Henderson R, Brorby G, Britt J, Harvey S, Goldberger J, Myers E, O’Brien C, Peck J, Lieberman H, Weaver C, Tenebein M. 2015. Systematic review of the adverse cardiovascular effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026673 Available from http://www.crd.york.ac.uk/PROSPERO/display_record. asp?ID=CRD42015026673 (Systematic Review Protocol Registration)

Ulrich, K. Inhalation toxicology – Regulatory aspects for pharmaceuticals. Presentation to In Vitro Toxicology Society Annual Meeting, Birmingham, UK, 2015.

Ulrich, K. Requirements of nonclinical inhalation studies for clinical development and registration. Presentation to British Society of Toxicological Pathologists (BSTP) — Continuing Education Symposium 4, Department of Pathology, Cambridge, UK, 2015.

Mackay CE, Vivanco SN, Reinhardt TE, McClure S, Vercellone J. 2015. Real-time monitoring and assessment of thermal and toxicological risk associated with fire retardant textiles in a full-size simulation of an engulfment flash fire. Fire Technol 51(5):1167–1193.

View Abstract

Chesney AR. Chronic wasting disease in Wisconsin. University of Wisconsin/Native Nations Summit on Environment and Health, Madison, WI, 2015.

Chesney AR. In situ chemical oxidation of pathogenic prion protein and implications for remediation of environmental chronic wasting disease agent. Molecular and Environmental Toxicology Seminar, University of Wisconsin, Madison, 2015.

Chesney AR. Pre-research workshops: The effectiveness of pre-research workshops in increasing preparedness of bioscience undergraduates starting involvement in research. CIRTL Teaching as Research Webcast, 2015.

Pedersen JA, Smith CB, Jacobson KH, Melby ES, Chesney AR. Attachment of pathogenic prion protein to humic substances. American Chemical Society National Meeting, San Francisco, CA, August 2015.

Chesney AR, Johnson CJ, Pedersen JA. In vitro amplification of neuropathogenic proteins. Alzheimer’s and Parkinson’s Disease Day, Madison, WI, March 2015.

Chesney AR, Johnson CJ, Nichols TA, Kornely H, Shoukfeh D, Pedersen JA. Chronic wasting disease prions detected during early stages of infection by mbPMCA in tissues from white-tailed deer orally inoculated with free and microparticle-bound prions. International PRION Conference, Fort Collins, CO, May 2015.

McMillan DA. Safety of botanical/natural substances in cosmetic products — An industry perspective. 15th Annual Oxford International Conference on the Science of Botanicals, Oxford, MS, April 2015.

Hughes BJ, LeBaron MJ, Thomas J, Kan HL, Lynch AM, Borghoff SJ, Green S, Mensing T, Sarang SS, Smulders CJGM. 2015. Activation of CAR and PXR nuclear receptors in the liver of MIBK-exposed mice. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, 2015. San Diego, CA.

View Abstract

Kirman CR, Proctor DM, Suh M, Hays S. 2015. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Suh M, Mittal L, Hirsch S, Valdes R, Bartlett C, Rohr A, Proctor D. 2015. Lung cancer risk in chromate production workers exposed to hexavalent chromium. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Britt J, James R. 2015. Welding and occupational exposure to manganese fumes and Parkinson’s disease:  An evidence-based causation analysis. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Doepker C, Brorby G. 2015. The role of the toxicologist in required food safety plans:  A case study of ochratoxin A (OTA) in coffee. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Proctor D, Suh M, Thompson C, Hixon, G. 2015. Inhalation cancer risk assessment of titanium dioxide. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Urban JD, Thompson CM, Plunkett LM, Perry CS, Haws LC. 2015. A state of the science copper reference dose for soil remediation. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Harris MA, Thompson CM, Proctor DM, Suh M, Wolf JC, Seiter JM, Chappell MA, Haws LC. 2015. Analysis of duodenal crypt health following exposure to Cr(VI) in drinking water. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Thompson CM, Young RR, Suh M, Dinesdurage H, Elbekai R, Harris MA, Rohr AC, Proctor DM. 2015. Hexavalent chromium does not induce mutations in the oral mucosa of transgenic Big Blue® rats following drinking water exposures at a carcinogenic dose. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Thompson CM, Suh M, Hixon G, Bichteler A. 2015. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Borghoff SJ, Wikoff D, White MC, Thompson C, Haws LC. 2015. Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Wikoff D, White MC, Borghoff SJ, Haws LC. 2015. Evaluation of tetrabromobisphenol A (TBBPA)-induced endocrine-related target gene activity using high-throughput screening data from ToxCast. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

View Abstract

Brorby G, Suh M, Bichteler A, Proctor D. Use of cluster analysis and homogeneity testing to characterize distributions of exposures among beryllium workers: Tools for developing occupational exposure limits from quantitative risk assessment.  Presented at International Society of Exposure Science 25th Annual Meeting, Henderson, NV, October 18-22, 2015.

Thompson CM, Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M, Proctor DM, Bichteler A, Haws LC, Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66.

View Abstract

Klaren WD, Robertson LW. PCB126-mediated disruption of hepatic metal homeostasis in mice and the role of metallothionein. Society of Toxicology Annual Meeting, San Diego, Ca, 2015.

View Abstract

Klaren WD, Vine D, Vogt S, Robertson LW. Spatial distribution of hepatic metals following PCB126 exposure. Society of Toxicology, Central States Regional Chapter Annual Meeting, Kansas City, Ks, 2015.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Society of Toxicology, Central States Regional Chapter Annual Meeting, Kansas City, Ks, 2015.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Superfund Annual Meeting, San Juan, Puerto Rico, 2015.

Mason AM, Spencer PJ, Panko JM. A pilot project reveals prominent hazard screening tools fall short on performance expectations. Poster at the 54th Annual Meeting and Society of Toxicology (SOT) Meeting, San Diego, CA, March 22–26, 2015.

View Abstract

Panko JM, Hitchcock KM, Fung M, Spencer PJ, Kingsbury T, Mason AM. A comparative evaluation of seven hazard screening tools. Poster at 25th Annual Meeting of NorCal SETAC, Sacramento, CA, April 29–30, 2015.

Panko JM, Hitchcock KM. From critical reviews of hazard assessment tools to building a product evaluation framework: Can we bridge the gaps with a super tool? Presentation at the American Industrial Hygiene Conference & Expo (AIHce), Salt Lake City, UT, May 30 – June 4, 2015.

Unice KM, Bare JL, Kreider ML, Panko JM. Evaluation of leachate from tire and road wear particles (TRWP) upflow percolation column tests. Poster at Society of Environmental Toxicology and Chemistry, 36th Annual Meeting, Salt Lake City, UT, November 1–5, 2015.

Klaren WD, Gadupudi GS, Wels B, Simmons DL, Olivier AK, Ludewig G, Robertson LW. 2015. Progression of micronutrient alteration and hepatotoxicity following acute exposure to PCB126. Toxicology 338:1–7, PMID: 26410179.

View Abstract

Klaren WD, Gadupudi GS, Wels B, Simmons DL, Olivier AK, Robertson LW. Progression of micronutrient alteration and hepatotoxicity following acute PCB126 exposure. Best Poster Award, Superfund Annual Meeting, San Juan, Puerto Rico, 2015.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Superfund Annual Meeting, San Juan, Puerto Rico, 2015.

View Abstract

Gauthier AM, Fung M, Panko J, Kingsbury T, Perez AL, Hitchcock K, Ferracini T, Sahmel J, Banducci A, Jacobsen M, Abelmann A, Shay E. 2015. Chemical assessment state of the science: Evaluation of 32 decision-support tools used to screen and prioritize chemicals. Integr Environ Assess Manag 11(2):242–255.

View Abstract

Kreider ML, Cyrs WD, Tosiano MA, Panko JM. 2015. Evaluation of quantitative exposure assessment method for nanomaterials in mixed dust environments: Application in tire manufacturing facilities. Ann Occup Hyg
59(9):1122–1134.

View Abstract

Rish W. Everything old is new again: 110 years of assessing risks of underground injection of waste. Ground Water Protection Council UIC Annual Conference, Austin, Texas, February 2015.

Rish W. Health risks from drinking water impacted by a flowback water spill in the Marcellus Shale region. Presented at the Ground Water Protection Council Annual UIC Conference, Austin, Texas, February 2015.

Rish W. Understanding induced seismicity risk from hydraulic fracturing. Presented at Ohio Oil and Gas Association Winter Meeting, March 2015.

Rish W. Prioritization, risk evaluation, and safety determinations under the Frank Lautenberg Chemical Safety Act for the 21st Century. Presented at Ohio Chemistry Technology Council Meeting, June 11, 2015.

Thompson CM, Young RR, Suh M, Dinesdurage HR, Elbekai RH, Harris MA, Rohr AC, Proctor DM. 2015. Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats. Environ Mol Mutagen 56:621-628.

View Abstract

James RC, Roberts SM, Williams PL. 2015. General principles of toxicology. In: Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York.

Young RR, Thompson CM, Dinesdurage HR, Elbekai RH, Suh M, Rohr AC, Proctor DM. 2015. A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats. Environ Mol Mutagen 56:629-636.

View Abstract

James RC, Roberts SM. 2015. Hepatoxicity: Toxic effects on the liver. In: Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York, NY.

Stuchal LD, James RC, Roberts SM. 2015. Human health risk assessment. In: Principles Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York, NY.

Borghoff SJ, Poet TS, Green S, Davis J, Hughes B, Mensing T, Sarang SS, Lynch AM, Hard GC.  2015. Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding. Toxicology 333(2015):1-13.

View Abstract

Heintz MM, Brander SM, White JW. 2015. Endocrine disrupting compounds alter risk-taking behavior in guppies (Poecilia reticulata). Ethology 121:480–491.

View Abstract

Britt JK. 2015. Properties and effects of pesticides. In: Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition. John Wiley and Sons, New York.

Urban JD, Carakostas MC, Taylor SL. 2015. Steviol glycoside safety: Are highly purified steviol glycoside sweeteners food allergens? Food Chem Toxicol 75: 71-78.

View Abstract

Thompson CM, Seiter J, Chappell MA, Tappero RV, Proctor DMSuh M, Wolf JC, Haws LC, Vitale R, Mittal L, Kirman CR, Hays SM, Harris MA. 2015. Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water. Toxicol Sci 143(1): 16-25.

View Abstract

Duckworth K, Spencer M, Bates C, Almquist C, Grimaila M, Magnuson M, Willison S, Phillips R, Racz L., Miller M. 2015. Advanced oxidation degradation kinetics as a function of ultraviolet LED duty cycle. Water Sci Technol 71(9):1375–1381.

Mihalchik AL, Ding W, Porter D, McLoughlin C, Schwegler-Berry D, Sisler JD, Stefaniak A, Snyder-Talkington BN, Cruz-Silva R, Terrones M, Tsuruoka S, Endo M, Castranova V, Qian Y. Effects of pristine and nitrogen-doped multiwalled carbon nanotubes (ND-MWCNT) on reactive oxygen species (ROS) and cell cycle progression. Poster session presented at the Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

View Abstract

Unice KM, Bare JL, Kreider ML, Panko JM. 2015. Evaluation of leachate from tire and road wear particles (TRWP) upflow percolation column tests. Poster Presentation at Society of Environmental Toxicology and Chemistry (SETAC) North America 36th Annual Meeting, Salt Lake City, UT, November 2015.

Unice KM, Bare JL, Kreider ML, Panko JM. 2015. Experimental methodology for assessing the environmental fate of organic chemicals in polymer matrices using column leaching studies and OECD 308 water/sediment systems: Application to tire and road wear particles. Sci Tot Environ 533:476–487.

View Abstract

Lea I, Rashid A, Favaro C, Fostel J. Chemical Effects in Biological Systems (CEBS) database: Advanced histopathology search applications. Presented at the 54th Annual Meeting of Society of Toxicology, San Diego, CA, March 2015. Abstract 2195-P410.

View Abstract

Mihalchik AL, Ding W, McLoughlin CE, et al. 2015. Effects of pristine and nitrogen-doped multiwalled carbon nanotubes (ND-MWCNT) on reactive oxygen species (ROS) and cell cycle progression. In: The Toxicologist (p. 267), abstract of work presented at the Society of Toxicology 54th Annual Meeting, San Diego, CA, March.

View Abstract

Mihalchik AL, Ding W, Porter D, McLoughlin C, Schwegler-Berry D, Sisler JD, Stefaniak A, Snyder-Talkington BN, Cruz-Silva R, Terrones M, Tsuruoka S, Endo M, Castranova V, Qian Y. 2015. Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells. Toxicology 333:25–36.

View Abstract

Wikoff D, Doepker C, Welsh B, Goldberger J, Lieberman H, Myers E, O’Brien C, Peck J, Tenebein M, Weaver C. Systematic review of the adverse behavioral effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015027413 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015027413 (Systematic Review Protocol Registration)

Wikoff D, Doepker C, Welsh B, Harvey S, Goldberger J, Lieberman H, Myers E, O’Brien C, Peck J, Tenebein M, Urban J, Weaver C. Systematic review of the adverse reproductive and developmental effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026736 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015026736 (Systematic Review Protocol Registration)

Wikoff D, Doepker C, Welsh B, Harvey S, Goldberger J, Lieberman H, Myers E, O’Brien C, Peck J, Tenebein M, Urban J, Weaver C. Systematic review of acute adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. PROSPERO 2015:CRD42015026704 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015026704 (Systematic Review Protocol Registration)

2014

Wikoff D, Thompson C, Perry C, White M, Borghoff S, Fitzgerald L, Haws LC. 2014. Development of toxicity values and exposure estimates for tetrabromobisphenol A [TBBPA]: Application in a margin of exposure assessment. J Appl Toxicol 35(11):1292-1308. doi: 10.1002/jat.3132.

View Abstract

Fitzgerald L, Wikoff DS. 2014. Persistent organic pollutants. In: Wexler P (Ed.), Encyclopedia of Toxicology, 3rd edition, vol 3. Elsevier, Inc., Academic Press, pp. 820-825.

Borghoff SJ, Hard GC, Poet TS, Davis J, Green S, Hughes B, Mensing T, Sarang SS. 2014. Methyl isobutyl ketone (MIBK) induces an exposure-related increase in measures of a2u-globulin (a2u) nephropath in male but not female F344 rats. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Kerger BD, James RC, Galbraith DA. 2014. Tumors that mimic asbestos-related mesothelioma: Time to consider a genetics-based tumor registry? Frontiers in Genetics 5(151):1-14.

View Abstract

Haws LC, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Wikoff D. 2014. Development of non-cancer based toxicity factors and daily dose estimates for TBBPA. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Kirman CR, Proctor D, Suh M, Thompson CM, Harris MA, Haws LC, Hays SM. 2014. Variation analysis of PBPK model parameters for describing the delivery of Cr(VI) to the small intestines of humans. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Proctor DM, Suh M. Campleman SL, Thompson CM. 2014. Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures. Toxicology 325:160-179.

View Abstract

Hays SM, Kirman CR, Suh M, Proctor DM.  2014. Gastric reduction of hexavalent chromium [Cr(VI)] in fed and fasted human stomach samples. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Vivanco S. Protecting the movie industry from lead generated by pyrotechnic effects. Presentation to AMEC Technical Summit, 2014.

Chesney AR. Mechanisms of enhanced transmission of prion disease in the context of microparticles. Chronic Wasting Disease meeting, National Wildlife Health Center, U.S. Geological Survey, 2014.

Pedersen JA, Shaffer CJ, Lietz CB, Chesney AR, Li L. Inactivation of disease-associated prion protein by peroxymonosulfate. International PRION conference, Trieste, It, May 2014.

Strittholt CA, Schowanek D, Barker ML, McMillan DA. Deterministic and probabilistic exposure modeling of data generated from a randomized clinical study investigating dentifrice ingestion in children. International Society of Exposure Science (ISES) meeting, Cincinnati, OH, October 2014.

Johnson GE, Soeteman-Hernandez, Gollapudi BB, Bodger OG, Dearfield KL, RH Heflich, Hixon JG, Lovell DP, MacGregor JT, Pottenger LH, Thompson CMAbraham L, Thybaud V, Tanir JY, Zeiger E, van Benthem J, White PA. 2014. Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment. Environ Molec Mutagen 55(8):609-623. doi: 10.1002/em.21870/em.21870.

View Abstract

Henderson R, Verougstraete V, Anderson K, Arbildua JJ, Brock TO, Brouwers T, Cappellini D, Delbeke K, Herting G, Hixon GOdnevall Wallinder I, Rodriguez PH, Van Assche F, Wilrich P, Oller AR. 2014. Inter-laboratory validation of bioaccessibility testing for metals. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Lancaster JL, Antonijevic T, Starobin JM. 2014. Ordering and stability in lipid droplets with applications to low-density lipoproteins. Physical Review E89(6):062708.

View Abstract

Henderson R, Verougstraete V, Anderson K, Arbildua JJ, Brock TO, Brouwers T, Cappellini D, Delbeke K, Herting G, Hixon G, Wallinder IO, Rodriguez PH, Assche FV, Wilrich P, Oller AR. 2014. Interlaboratory validation of bioaccessibility testing for metals. Regul Toxicol Pharmacol 70(1):170-181. doi: 10.1016/j.yrtph.2014.06.02.

View Abstract

Hixon JG, Thompson C, Bichteler A, Abraham L. 2014. Smoothing regression splines as the basis for dose-response modeling. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Klaren WD and Robertson LW. PCB126-mediated disruption of hepatic metal homeostasis in mice coincides with increased metallothionein expression and appears to be independent of the canonical AhR pathway. Best Poster Award, University of Iowa Research Week, 2014.

Panko JM. Green chemistry: A critical element of sustainable development and product stewardship. Presentation at The American Industrial Hygiene Conference & Exposition (AIHce), San Antonio, TX, May 31 – June 5, 2014.

Kreider ML, Cyrs WD, Tosiano MA, Panko JM. Method development for nanomaterials exposure assessment in mixed dust environments. Presentation at The American Industrial Hygiene Conference & Exposition (AIHce), San Antonio, TX, May 31 – June 5, 2014.

Cyrs WD, Tosiano MA, Panko JM, Kreider ML. Use of a novel method to assess exposure to nanoscale carbon black and amorphous silica at two tire manufacturing facilities. Presentation at The American Industrial Hygiene Conference & Exposition (AIHce), San Antonio, TX, May 31 – June 5, 2014.

Panko JM. Chemical selection tools analysis project & results. Presented at GlobalChem. Global Chemical Regulations Conference, Baltimore, MD, March 3–5, 2014.

Faber W, Kirkpatrick D, Coder P, Li P, Borghoff S, Banton M. 2014. Subchronic, reproductive, and maternal toxicity studies with tertiary butyl acetate (TBAC). Regul Toxicol Pharmacol 68:332-342.

View Abstract

Proctor DM, Suh M, Tachovsky JA, Abraham L, Hixon JG, Brorby GP, Campleman SL. 2014. Cumulative risk assessment of urban air toxics: A pilot study in San Antonio, Texas. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Wu T, Wang XJ, Tian W, Jaramillo MC, Lau A, Zhang DD. 2014. Poly(ADP-ribose)polymerase-1 modulates Nrf2-dependent transcription. Free Radic Biol Med 67:69–80, doi: 10.1016/j.freeradbiomed.2013.10.806.

View Abstract

Beasley TE, Evansky PA, Martin SA, McDaniel KL, Moser VC, Luebke RW, Norwood J Jr, Rogers JM, Copeland C, Bushnell PJ. 2014. Toxicological outcomes in rats exposed to inhaled ethanol during gestation. Neurotoxicol Teratol 45:59–69.

View Abstract

Daston GP, Beyer BK, Carney EW, Chapin RE, Friedman JM, Piersma AH, Rogers JM, Scialli AR. 2014. Exposure-based validation list for developmental toxicity screening assays. Birth Defects Res, Part B, Dev Reprod Toxicol 101:423–428.

View Abstract

Rogers JM, RE Ellis-Hutchings, BE Grey, RM Zucker, J Norwood, Jr., CE Grace, C Gordon, C Lau. 2014. Elevated blood pressure in offspring of rats exposed to diverse chemicals during pregnancy. Toxicol Sci
137:436–446.

View Abstract

James RC, Britt J, Halmes N, Guzelian P. 2014. Comments on recent discussions providing differing causation methodologies. Hum Experim Toxicol 33(1):109-112.

View Abstract

Suh M, Yzenas JJ, Proctor DM. 2014. Evaluation of electric arc furnace-processed steel slag for dermal corrosion, irritation, and sensitization. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Janeczko AK, Walters EB, Schuldt SJ, Magnuson ML, Willison SW, Brown LM, Ruiz ON, Felker DL, Racz L. 2014. Fate of malathion and a phosphonic acid in activated sludge with varying solids retention times. Water Res 57:127–139.

View Abstract

Delorit JD, Racz L. 2014. Evaluation of activated sludge for biodegradation of propylene glycol as an aircraft deicing fluid. Water Environ Res 86(4):366–371.

View Abstract

King ST, Sylvander M, Kheperu M, Racz L, Harper WF. 2014. Detecting recalcitrant organic chemicals in water with microbial fuel cells and artificial neural networks. Sci Tot Environ 497–498:527–533.

View Abstract

Tran T, Racz L, Grimaila MR, Miller M, Harper WF Jr. 2014. Comparison of continuous versus pulsed ultraviolet light emitting diode use for the inactivation of Bacillus globigii spores. Water Sci Technol 70(9):1473–1480.

View Abstract

Boice JD, Cohen SS, Mumma MT, Ellis ED, Cragle DL, Eckerman KF, Wallace PW, Chadda B, Sonderman JS, Wiggs LD, Richter BS, Leggett RW.  2014. Mortality among mound workers exposed to polonium-210 and other sources of radiation, 1944–1979. Radiat Res 181(2):208-228, DOI: 10.1667/RR13395.1.

View Abstract

Mihalchik AL, McLoughlin C, Schwegler-Berry D, Farcas M, Shvedova A, Porter D, Tsuruoka S, Endo M, Castranova V, Qian Y. Nitrogen-doped multi-walled carbon nanotube-induced effects in human small airway epithelial cells. Poster session presented at the West Virginia University Bench to Bedside: Translational Pharmacy Meeting, Morgantown, WV, June 2014.

Juberg DR, Borghoff SJ, Becker RA, Casey W, Hartung T, Holsapple MP, Marty MS, Mihaich EM, Van Der Kraak G, Wade MG and others. 2014. t4 Workshop report — Lessons learned, challenges, and opportunities: The U.S. Endocrine Disruptor Screening Program. Altex 31(1):63-78.

View Abstract

Thompson CM, Proctor DM, Suh M, Wolf JC, Haws LC, Seiter JM, Chappell MA, Harris MA. 2014. X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Gentry R, Clewell H, Greene T, Franzen A, Yager J. 2014. The impact of recent advances in research on arsenic cancer risk assessment. Regul Toxicol Pharmacol 69(1):91–104.

View Abstract

Song G, Darr DB, Santos CM, Ross M, Valdivia A, Jordan JL, Midkiff BR, Cohen S, Feinberg NN, Miller CR, Tarrant TK, Rogers AB, Dudley AC, Perou CM, Zamboni WC. 2014. Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models. Clin Cancer Res 20(23):6083–6095.

View Abstract

Bhusari S, Malarkey DE, Hong HH, Wang Y, Masinde T, Nolan M, Hooth NJ, Lea IA, Vasconcelos D, Sills RC, Hoenerhoff MJ. 2014. Mutation spectra of Kras and Tp53 in urethral and lung neoplasms in B6C3F1 mice treated with 3,3′,4,4′-tetrachloroazobenzene. Toxicol Pathol 42(3):555–564.

View Abstract

Suh M, Troese MJ, Hall DA, Yasso B, Yzenas JJ, Proctor DM. 2014. Evaluation of electric arc furnace-processed steel slag for dermal corrosion, irritation, and sensitization from dermal contact. J Appl Toxicol 34(12):1418-1425. DOI: 10.1002/jat.2974.

View Abstract

Urban JD, Doepker CL, Cuellar-Kingston N, van de Ligt J, Carakostas M. 2014. Do highly purified steviol glycoside sweeteners cause food allergies? Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

View Abstract

Wikoff, D., Thompson, C., Perry, C., White, M., Fitzgerald, L., Borghoff, S., Haws, L.C. Development of an oral cancer slope factor and lifetime average daily dose estimates for TBBPA. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, 2014. Phoenix, AZ.

View Abstract

Bunch AG, Perry CS, Abraham L, Wikoff DS, Tachovsky JA, Hixon JG, Urban JD, Harris MA, Haws LC. 2014. Evaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks. Sci Tot Environ 468-469(2014):832-842.

View Abstract

Suh M, Abraham L, Hixon JG, Proctor D. 2014. The effects of perchlorate, nitrate, and thiocyanate on free thyroxine for potentially sensitive subpopulations of the 2001–2002 and 2007–2008 National Health and Nutrition Examination Surveys. J Expos Sci Epidemiol 24:579-587.

View Abstract

Urban JD, Wikoff DS, Bunch ATG, Harris MA, Haws LC. 2014. A review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels. Sci Tot Environ 466-467:586-597.

View Abstract

Thompson CM, Kirman CR, Proctor DMHaws LCSuh M, Hays S, Hixon JG, Harris MA. 2014. A chronic oral reference dose for hexavalent chromium-induced intestinal cancer. J Appl Toxicol 34:525-536. doi: 10.1002/jat.2907.

View Abstract

Mahadevan B, Thorsrud BA, Brorby GP, Ferguson HE. 2014. A 3-week dietary safety study of octenyl succinic anhydride (OSA)-modified starch in neonatal farm piglets. Food Chem Toxicol 72:83-89.

View Abstract

Suh M, Thompson C, Kirman C, Carakostas M, Haws LC, Harris M, Proctor D. 2014. High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice. Food  Chem Toxicol 65:381-388.

View Abstract

2013

Henderson R, Verougstraete V, Anderson K, Arbildua JJ, Brock TO, Brouwers T, Cappellini D, Delbeke K, Herting G, Hixon GOdnevall Wallinder I, Rodriguez PH, Van Assche F, Wilrich P, Oller AR. 2013. Interlaboratory comparison of bioaccessibility tests for metals. Annual meeting of the Belgian Society for Toxicology and Ecotoxicology (BelTox).

MacDonell MM, Haroun LA, Teuschler LK, Rice ER, Hertzberg RC, Butler JP, Chang Y, Clark S, Johns AP, Perry CS, Garcia SS, Jacobi JH, Scofield MA. 2013. Cumulative risk assessment toolbox: Methods and approaches for the practitioner. J Toxicol 2013:310904.

View Abstract

Kirman CR, Aylward LL, Suh MHarris MAThompson CMHaws LCProctor DM, Lin SS, Parker W, Hays SM. 2013. Physiologically based pharmacokinetic model for humans orally exposed to chromium. Chem Biol Interact 204(1):13-27. doi:pii: S0009-2797(13)00082-3. 10.1016/j.cbi.2013.04.003.

View Abstract

Dourson ML, Gadagbui B, Griffin S, Garabrant DH, Haws LC, Kirman C, Tohyama C. 2013. The importance of problem formulations in risk assessment: A case study involving dioxin-contaminated soil. Regul Toxicol Pharmacol 66(2):208-216.

View Abstract

Lamm SH, Britt JK, James RC. 2013. Multiple myeloma risk and benzene exposure among pliofilm workers – A re-analysis using an internal reference group. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

O’Brien T, Ding H, Suh MThompson C, Parsons BL, Harris MA, Winkelman WA, Wolf JC, Hixon JG, Schwartz AM, Myers MB, Haws LC, Proctor DM. 2013. Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water. Mutat Res 754:15-21. doi: 10.1016/j.mrgentox.2013.03.008

View Abstract

Wikoff D, Fitzgerald L, Haws L, Harris M. 2013. Health-based framework for evaluating the safety of hydraulic fracturing products. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

Chesney AR. Early prion disease pathogenesis: Avenues of disease potentiation in the gastrointestinal and lympho-reticular system. Molecular and Environmental Toxicology Seminar. University of Wisconsin, Madison, 2013.

Chesney AR, Johnson CJ, Pedersen JA. Detection of pathogenic prion protein in formalin-fixed tissues by protein misfolding cyclic amplification (PMCA). Society of Toxicological Pathology National Conference, Portland, OR, June 2013.

King BH, Kolyott KL, Chesney AR. 2013. Livestock bedding effects on two species of parasitoids (Hymenoptera: Pteromalidae) of filth flies. J Insect Sci 14:185.

View Abstract

Rowlands JC, Budinsky R, Gollapudi B, Black MB, Wolfinger RD, Cukovic D, Bombkowski A, Thompson CM, Urban JD, Thomas RS. 2013. A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes. Toxicol Sci 136(2):595-604.

View Abstract

Thompson CMProctor DMSuh MHaws LC, Kirman CR, Harris MA. 2013. Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans. Crit Rev Toxicol 43(3): 244-274.

View Abstract

Suh M, Thompson CM, Hixon JG, Harris MA, Kirman CR, Hays S Haws LC, Proctor DM. 2013. Potential involvement of oxidative stress and iron disturbance in the development of oral cavity tumors in rats exposed to hexavalent chromium. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

Haws L, Hixon GDeVito M, Walker N, Kuriakose L, Harris M, Birnba0um L, Wikoff D. 2013. Development of weighted distributions of relative potency estimates for dioxin-like compounds. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

Klaren WD, Lai IK, Robertson LW. Search for the basis of PCB126-triggered disruption of hepatic metal homeostasis in rodents. Society of Toxicology Annual Meeting, San Antonio, Tx, 2013.

Klaren WD, Robertson LW. PCB126 induced increases in metallothionein expression may be species specific and AhR dependent. Society of Toxicology, Central States Regional Chapter Annual Meeting, Ames, Ia, 2013.

Klaren WD, Robertson LW. Increases in metallothionein expression caused by PCB126 are linked to species sensitivity and are potentially mediated through the AhR. Superfund Annual Meeting, Baton Rouge, La, 2013.

Kreider ML, Unice KM, Panko JM. Framework for quantitative exposure assessment of nanostructured materials in occupational settings. Presented at the TechConnect World 2013 — Nanotech, Microtech, Biotech, Cleantech Joint 2013 Conferences, Washington, DC, May 12–15, 2013.

Panko JM, Kreider NK, Unice KM. Tire industry project — An industry-wide product sustainability initiative. Session: Stewardship & Sustainability, Presentation at The American Industrial Hygiene Conference & Exposition (AIHce) in Montreal, Quebec, May 20, 2013.

Avens HJ, Gross S, Banducci AM, Sahmel J, Tvermoes BE, Panko JM. Characterization of surface spills associated with hydraulic fracturing operations. Session: Oil and Gas, Presentation at The American Industrial Hygiene Conference & Exposition (AIHce) in Montreal, Quebec, May 21, 2013.

Kingsbury T, Gauthier AM, Ferracini TV, Panko JM, Perez AL. Predicting chemistries targeted for deselection: A case study with triclosan. Session: Stewardship & Sustainability. Poster at The American Industrial Hygiene Conference & Exposition (AIHce) in Montreal, Quebec, May 21, 2013.

Gauthier AM, Kingsbury T, Ferracini TV, Panko JM. Beyond the standards: Comparing sustainability reports of consumer products companies. Session: Stewardship & Sustainability. Poster at The American Industrial Hygiene Conference & Exposition (AIHce) in Montreal, Quebec, May 21, 2013.

Tosiano MA, Panko JM, Scott PK. Risk based evaluation of the chemical constituents in hydraulic fracturing fluid using the chemical disclosure registry FracFocus. Poster at Society of Environmental Toxicology and Chemistry, 34th Annual Meeting, Nashville, TN, November 11–14, 2013.

Hitchcock KM, Shay ED, Panko JM. Making product and chemical safety decisions from varying stakeholder viewpoints. Poster platform presentation at Society of Environmental Toxicology and Chemistry, 34th Annual Meeting, Nashville, TN, November 11–14, 2013.

Shay EC, Panko JM. Community-focused remediation and risk assessment at a former manufactured gas plant site. Poster at Society of Environmental Toxicology and Chemistry, 34th Annual Meeting, Nashville, TN, November 11–14, 2013.

Lai IK*, Klaren WD*, Li M, Wels B, Simmons DL, Olivier AK, Haschek WM, Wang K, Ludewig G, and Robertson LW. 2013. Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver? Lai Chem Res Toxicol 26(5):634–644 (*Co-First Authors), PMID: 23527585.

View Abstract

Brorby GP, Sheehan PJ, Berman DW, Bogen KT, Holm SE. 2013. Exposures from chrysotile-containing joint compound: Evaluation of new model relating respirable dust to fiber concentrations. Risk Analysis 33(1): 161-176.

View Abstract

Urban JD, Thompson CM, Deskin R, Waite M, Haws LC. 2013. Development of an oral cancer slope factor for acrylamide based on tumors relevant to humans. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

Panko JM, Chu J, Kreider ML, Unice KM. 2013. Measurement of airborne concentrations of tire and road wear particles in urban and rural areas of France, Japan, and the United States. Atmos Environ 72:192–199.

View Abstract

Gross SA, Avens HJ, Banducci AM, Sahmel J, Panko JM, Tvermoes BE. 2013. Analysis of BTEX groundwater concentrations from surface spills associated with hydraulic fracturing operations. J Air Waste Manage Assoc 63(4):424–432.

View Abstract

Kreider ML, Burns AM, DeRose GH, Panko JM. 2013. Protecting workers from risks associated with nanomaterials: Part II — Best practices in risk management. Occup Safety Health 82(9):20–24.

View Abstract

Kreider ML, Burns AM, DeRose GH, Panko JM. 2013. Protecting workers from risks associated with nanomaterials: Part I — Exposure assessment. Occup Safety Health 82:7.

View Abstract

Unice KM, Kreider ML, Panko JM. 2013. Comparison of tire and road wear particle concentrations in sediment for watersheds in France, Japan, and the United States by quantitative pyrolysis GC/MC analysis. Environ Sci Technol 47(15):8138–8147.

View Abstract

Lau A, Whitman SA, Jaramillo MC, Zhang DD. 2013. Arsenic-mediated activation of the Nrf2-Keap1 antioxidant pathway. J Biochem Mol Toxicol 27(2):99–105, doi: 10.1002/jbt.21463.

View Abstract

Lau A, Zheng Y, Tao S, Wang H, Whitman SA, White E, Zhang DD. 2013. Arsenic inhibits autophagic flux activating the Nrf2-Keap1 pathway in a p62-dependent manner. Mol Cell Biol 33(12):2436–2446, doi: 10.1128/MCB.01748-12.

View Abstract

Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD. 2013. USP15 negatively regulates Nrf2 through deubiquitination of Keap1. Mol Cell 51(1):68–79, doi: 10.1016/j.molcel.2013.04.022.

View Abstract

Urban JD, Carakostas MC, Brusick, DJ. 2013. Steviol glycoside safety: Is the genotoxicity database sufficient? Food Chem Toxicol 51:386-390.

View Abstract

Thompson CM, Kirman CR, Proctor DM, Suh M, Hays SM, Haws LC, Harris MA. 2013. A chronic oral reference dose for hexavalent chromium. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

Racz L, Baker PA, Duckworth KL, Heline TR, Woodall BD. 2013. Environmental planning while deployed: Mission hindrance or enhancement? Joint Force Quarterly 70:30–33.

View Abstract

Flory J, Kanel SR, Racz L, Impellitteri CA, Rendahandi GS, Goltz MN. 2013. Influence of pH on the transport of silver nanoparticles in saturated porous media: laboratory experiments and modeling. J Nanopart Res 15(3):2–11.

View Abstract

Fryzek J, Pastula S, Jiang X, Garabrant DH. 2013. Childhood cancer incidence in Pennsylvania counties in relation to living in counties with hydraulic fracturing sites. J Occup Environ Med 55(7):796–801.

View Abstract

Fryzek J, Pastula S, Jiang X, Garabrant DH. 2013. Response to Goldstein et al. J Occup Environ Med 55(11):1378.

View Abstract

Thompson CM, Gaylor DW, Tachovsky JA, Perry C, Carakostas MC, Haws LC. 2013. Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. J Appl Toxicol 33(12):1395-1406.

View Abstract

Proctor DM, Suh M, Thompson CM, Harris MA. 2013. Mode of action evaluation for hexavalent chromium-induced lung cancer. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

Kirman CR, Thompson CM, Proctor DM, Suh M, Haws LC, Harris MA, Hays SM. 2013. Using PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

View Abstract

2012

Kirman, CR, Hays, SM, Aylward, LL, Suh, M, Harris, MA, Thompson, CM, Haws, LC, Proctor, DM. 2012. Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium. Chem Biol Interact 200(1):45-64.

View Abstract

Brorby G, Proctor D, Perry C, Fitzgerald L, Tachovsky A. 2012. Probabilistic risk assessment of human exposure to iron and steel slag. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Doepker CL, Maier A, Willis A, Hermansky S. 2012. Toxicology of flavors in the food industry. Chapter 7 In: Bingham E, Cohrssen B., eds. Patty’s Toxicology, Sixth ed. New York: Wiley & Sons.

Kopec AK, Thompson CM, Kim S, Forgacs AL, Zacharewski TR. 2012. Comparative toxicogenomic analysis of oral Cr(VI) exposure effects in rat and mouse small intestinal epithelium. Toxicol Appl Pharmacol 262(2):124-138.

View Abstract

Wikoff DW, Fitzgerald LBirnbaum L. 2012. Persistent organic pollutants: An overview. In: Schecter, A. (ed.), Dioxins and Health Including Other Persistent Organic Pollutants and Endocrine Disruptors, 3rd edition. John Wiley & Sons, Inc., pp. 1-35.

Kopec AK, Kim S, Forgacs AL, Zacharewski TR, Proctor DMHarris MAHaws LCThompson CM. 2012. Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water. Toxicol Appl Pharmacol 259(1):13-26.

View Abstract

Harris MA, Thompson CM, Wolf JC, Fedorov Y, Hixon JG, Proctor DM, Suh M, Haws LC. 2012. Assessment of genotoxic potential of Cr(VI) in the intestine via in vivo intestinal micronucleus assay and in vitro high content analysis in differentiated and undifferentiated caco-2. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Lamb DJ, Parker N, Ulrich K, Walsh R, Yeadon M, Evans SM. 2012. Characterisation of a mouse model of cigarette smoke extract-induced lung inflammation. J Pulmon Resp Med 2(3):open access, doi: 10.4172/2161-105X.1000125.

View Abstract

Gneiding L, Kelly C, Winters B, Vivanco S. Evaluation of selected substances in consumer products for PBT characteristics. Presentation to Society of Environmental Toxicology and Chemistry, November 2012.

Proctor DMSuh M, Aylward LL, Kirman CR, Harris MAThompson CM, Gürleyük H, Gerads R, Haws LC, Hays SM. 2012. Hexavalent chromium reduction kinetics in rodent stomach contents. Chemosphere 89(5): 487-493.

View Abstract

Haws L, Fitzgerald L, Burkhalter K, Wikoff D. 2012. US EPA’s proposed toxicity values for TCDD: Implications for decision-making regarding the safety of foods in the United States. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Thompson CM, Fedorov Y, Brown DD, Suh MProctor DM, Kuriakose L, Haws L, Harris MA. 2012. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS ONE 7(8): e42720.

View Abstract

Hays SM, Kirman C, Aylward L, Suh M, Proctor D. 2012. Gastric reduction of Cr(VI) in mice, rats and humans. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Suh M, Ke JG, Hixon G, Proctor DM. Urinary perchlorate, nitrate, thiocyanate and thyroid hormone levels in participants of National Health and Nutrition Examination Survey (NHANES) 2001-2002. Presented at the International Society of Environmental Epidemiology’s 24th Annual Meeting, Columbia, SC, August 26-30, 2012.

Wang B, Wels BR, Klaren WD, Wang K, Robertson LW, Ludewig G. Regulation of MnSOD by the AhR agonist PCB126: The role of dietary manganese. Society of Toxicology Annual Meeting, San Francisco, Ca, 2012. Also presented at Superfund Annual Meeting, Lexington, Ky, 2012.

View Abstract

Klaren WD, Lai IK, Robertson LW. Search for the basis of PCB-triggered disruption in hepatic copper in rodents. Best Poster Award, University of Iowa Research Week, Iowa City, Ia, 2012.

Klaren WD, Lai IK, Robertson LW. Search for the basis of PCB126-triggered disruption of hepatic metal homeostasis in rats. Superfund Annual Meeting, Raleigh, NC, 2012.

Panko JM. Evaluation of the potential aquatic toxicity of TRWP to algae, daphnids and fish. Tire Technology Expo, Cologne, Germany, February 14–16, 2012.

Panko JM, Zöller M, Tartaglino U, Peters F, Unice KM, Kreider ML, Crawford M. Tire and road wear particles: A comprehensive evaluation of environmental health issue. Tire Technology Expo, Cologne, Germany. February 14, 2012.

Panko JM. Ambient air quality associated with hydraulic fracturing operations. Presented at the 21st Annual Business and Industry’s Sustainability and Environmental Health & Safety Symposium, Cincinnati, OH, March 27, 2012.

Kreider ML, Panko JM, Finley BL. 2012. Effects of subacute inhalation exposure to tire and road wear particles in rats. Presented at the 2012 Health Effects Institute (HEI) Annual Conference, Chicago, IL, April 15–17, 2012.

Hitchcock K, Scott PK, Unice KM, Panko JM. Comparing the chemical footprint of hydraulic fracturing fluids used in natural gas extraction. Presented at the 6th SETAC World Congress and 22nd Annual SETAC Europe Meeting, Berlin, Germany, May 20–24, 2012.

Unice KM, Chu J, McAtee BL, Panko JM. Evaluation of tire and road wear particles in the Seine River watershed: A sustainability initiative of the global tire industry. Presented at the 6th SETAC World Congress and 22nd Annual SETAC Europe Meeting, Berlin, Germany, May 20–24, 2012.

Kreider ML, Panko JM. Effects of subacute inhalation exposure to tire and road wear particles in rats. Presented at Eurotox 2012, Stockholm, Sweden, June 17–20, 2012.

Unice KM, Chu J, Panko JM. Evaluation of tire and road wear particles in the Yodo River watershed: A global tire industry sustainability initiative. Presented at SETAC Asia/Pacific 2012 Meeting, Kumamoto, Japan, September 24–27, 2012.

Unice KM, Panko JM. Analytical method development and validation of a pyrolysis-GC/MS method to quantify tire and road wear particles in environmental samples. Presented at SETAC Asia/Pacific 2012 Meeting, Kumamoto, Japan, September 24–27, 2012.

Kreider ML, Unice KM, Panko JM. A case study in understanding exposure associated with nanostructured materials: Carbon black and amorphous silica. Presented at SETAC Asia/Pacific 2012 Meeting, Kumamoto, Japan, September 24–27, 2012.

Hitchcock KM, Panko JM, Scott PK, Unice KM, Shay EC. Responding to community concerns surrounding hydraulic fracturing activities near a school. SETAC North America 33rd Annual Meeting, Long Beach, CA, November 11–15, 2012.

Sahmel J, Cowan DM, Panko JM, Paustenbach DJ. 2012. Future trends in risk management: Control banding and REACH. Chapter 19 in: Perkins J, Gray C. (eds). Modern Industrial Hygiene, Volume III: Control of Chemical Agents, Part IV: Risk Management. ACGIH, Cincinnati, OH, pp. 727–764.

Hitchcock KM, Panko JM, Scott PK. 2012. Incorporating chemical footprint reporting into social responsibility reporting. Integr Environ Assess Manag 8(3):386–388.

View Abstract

Thompson CM, Hixon JG, Proctor DM, Haws LC, Suh M, Urban JD, Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1): 68-76.

View Abstract

Hixon JG, Proctor D. 2012. Use of constrained logistic regression models for the dose-response analysis of beryllium sensitization and chronic beryllium disease with mean exposure. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Panko JM, Kreider ML, McAtee BL, Marwood C. 2012. Chronic toxicity of tire and road wear particles to water- and sediment-dwelling organisms. Ecotoxicology 22(1):13–21, doi: 10.1007/s10646-012-0998-9.

View Abstract

Kreider ML, Doyle-Eisele M, Russell RG, McDonald JD, Panko JM. 2012. Evaluation of potential for toxicity from subacute inhalation of tire and road wear particles in rats. Inhal Toxicol 24(12):907–917.

View Abstract

Unice KM, Kreider ML, Panko JM. 2012. Use of a deuterated internal standard with pyrolysis-GC/MS dimeric marker analysis to quantify tire tread particles in the environment. Int J Environ Res Pub Health 9:4033–4055.

View Abstract

Lau A,* Wang H, Zhang DD. The effect of arsenic on the Nrf2-Keap1 pathway. Abstract for poster presentation, 51st Annual Meeting and ToxExpo, Society of Toxicology, San Francisco, CA, March 2012.

Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen HY, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. 2012. Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. PLoS One 7(7):e41831, doi: 10.1371/journal.pone.0041831.

View Abstract

Chen W, Jiang T, Wang H, Tao S, Lau A, Fang D, Zhang DD. 2012. Does Nrf2 contribute to p53-mediated control of cell survival and death? Antioxid Redox Signal 17(12):1670–1675, doi: 10.1089/ars.2012.4674.

View Abstract

Lau A, Tian W, Whitman SA, Zhang DD. 2012. The predicted molecular weight of Nrf2: It is what it is not. Antiox Redox Signal 18(1):91-93, doi:10.1089/ars.2012.4754.

View Abstract

Boekelheide K, Blumberg B, Chapin RE, Cote I, Graziano JH, Janesick A, Lane R, Lilycrop K, Myatt L, States JC, Thayer KA, Waalkes MP, Rogers JM .2012. Predicting later-life outcomes of early-life exposures. Environ Health Perspect 120:1353–1361.

View Abstract

Schugg TT, Erlebacher A, Leibowitz S, Ma L, Muglio LJ, Rando OJ, Rogers JM, Romero R, von Saal FS, Wise LD. 2012. Fetal programming and environmental exposures: Implications for prenatal care and preterm birth. Ann NY Acad Sci 1276:37–46.

View Abstract

Thompson CMProctor DMSuh MHaws LC, Hebert CD, Mann JF, Shertzer HG, Hixon JG, Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90.

View Abstract

Kim S, Kopec A, Forgacs AL, Thompson CM, Zacharewski T. 2012. Genome-wide gene expression analysis of Cr(VI) effects in Fisher rat small intestinal epithelium. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Thompson CMProctor DM, Harris MA. 2012. Duodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI). Toxicol Sci 126(1):287-288.

View Abstract

Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D. 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Berman DW, Brorby GP, Sheehan PJ, Bogen KT, Holm SE. 2012. More on the dynamics of dust generation: The effects of mixing and sanding chrysotile, calcium carbonate, and other compounds on the characteristics of joint-compound dusts. Ann Occup Hyg 56(7):852-867.

View Abstract

Kopec A, Forgacs AL, Kim S, Thompson CM, Zacharewski T. 2012. Comparative toxicogenomic analysis of Cr(VI) effects in rat and mouse small intestine. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Fowler, JC, Bhattacharya S, Urban JD, Vaidehi N, Mailman RB. 2012. Receptor conformations involved in dopamine D2L receptor functional selectivity induced by selected transmembrane 5 serine mutations. Mol Pharmacol 81(6):820-831.

View Abstract

Henderson RG, Durando J, Oller A, Merkel DJ, Marone PA,  Bates HK. 2012. Acute oral toxicity of nickel compounds. Regul Toxicol Pharmacol 62(3):425-432.

View Abstract

O’Brien TJ, Hao D, Suh M, Proctor D, Thompson CM, Harris MA, Parsons BL, Meyers MB. 2012. K-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Henderson RG, Cappellini D, Seilkop SK, Bates HK, Oller AR. 2012. Oral bioaccessibility testing and read-across hazard assessment of nickel compounds. Regul Toxicol Pharmacol 63(1):20-28.

View Abstract

Perry C, Tachovsky JA, Ke M, Urban J, Haws L. 2012. Natural gas exploration and production in the Barnett Shale: Assessment of exposures to volatile organic compounds (VOCs). Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Urban J, Budinsky R, Rowlands J. 2012. An evaluation of single nucleotide polymorphisms in the human heat shock protein 90kDa alpha and beta isoforms. Drug Metab Pharmacokinet 27(2):268-278.

View Abstract

Proctor DM, Thompson CM, Suh M, Haws LC, Harris MA. 2012. Mode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Thompson CM, Hixon JG, Kopec AK, Harris MA, Proctor DM, Haws LC. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Urban J, Rowlands JC, Budinsky R, Dombkowski A, Thompson CM, Thomas RS. 2012. A genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

Wikoff D, DeVito M, Walker N, Hixon G, Harris M, Tachovsky A, Birnbaum L, Haws L. 2012. Application of machine learning in the development of a weighting framework for evaluating eEstimates of relative potency for dioxin-like compounds. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

View Abstract

2011

Thompson CPerry C, Gaylor D, Tachovsky A, Burkhalter B, Haws L. 2011. Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Thompson CM, Proctor DM, Haws LC, Hebert CD, Grimes SD, Shertzer HG, Kopec AK, Hixon JG,  Zacharewski TR, Harris MA. 2011. Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium. Toxicol Sci 123(1): 58-70.

View Abstract

Bogen KT, Brorby GP, Berman DW, Sheehan PJ, Floyd M.  2011. Measuring mixed cellulose ester (MCE) filter mass under variable humidity conditions.  Ann Occup Hyg 55(5)485-494.

View Abstract

Urban J, Fitzgerald LBurkhalter B, Staskal D, Harris M, Haws L. 2011. BTEX serum levels in the general U.S. population: An analysis of 2003-2004 NHANES dataset. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Thompson CM, Haws LC, Harris MA, Gatto NM, Proctor DM. 2011. Application of the U.S. EPA mode of action framework for purposes of guiding future research: A case study involving the oral carcinogenicity of hexavalent chromium. Toxicol Sci 119(1):20-40.

View Abstract

Diliberto JJ, Sirinek L, Burkhalter B, Wikoff DS, Hixon G, Becker J, Patterson DG, Turner W, Tachovsky JA, Birnbaum LS, Haws LC. 2011. Endometriosis in a cohort of women living in the Kanawha River Valley in West Virginia: Blood levels of non-dioxin-like PCBs and relationship with BMI and age. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Oller A, Henderson RG. 2011. Bioaccessibility testing and its application to read-across for hazard assessment and risk characterisation of metals. Annual meeting of the Belgian Society for Toxicology and Ecotoxicology (BelTox).

Boice JD Jr, Cohen SS, Mumma MT, Ellis ED, Eckerman KF, Leggett RW, Boecker BB, Brill AB, Henderson BE. 2011. Updated mortality analysis of radiation workers at Rocketdyne (Atomics International), 1948-2008. Radiat Res 176(2):244-258.

View Abstract

Brorby GP, Sheehan PJ, Berman DW, Bogen KT, Holm SE. 2011. Potential artifacts associated with historical preparation of joint compound samples and reported airborne asbestos concentrations.  J Occup Environ Hyg 8(5):271–278.

View Abstract

Haws LC, DeVito MJ, Walker NJ, Harris MA, Tachovsky JA, Birnbaum LS, Farland WH, Wikoff DS. 2011. Development of a consensus-based weighting framework for evaluating estimates of relative potency for dioxin-like compounds that includes consideration of data from human cells. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Semeraro A, Patriarca M, Taylor A, Henderson R, Bates H. 2011. Nickel kinetics after oral exposure: Urinary excretion. IUPAC 4th International Symposium for Trace Elements in Food.

Vivanco S. IVAN’s effectiveness in identifying and addressing environmental harms in underserved communities. University of California, Los Angeles Fielding School of Public Health Graduate Seminar, Los Angeles, CA, fall 2011.

Bogeberg M, Vivanco S, Carmona-Galindo V. 2011. Relationship between soil sodium concentration and plant height in Salicornia virginica in the Ballona Wetlands in Los Angeles, CA. BIOS 82(4):112–116.

View Abstract

Regg BT, McMillan DA, Mahony C, Laufersweiler MC, Baker TR.  2011. Development of UHPLC/UV/CAD/Q-ToF-MS/MS methodology to characterize complex botanical mixtures. Presented at the American Society for Mass Spectroscopy, 2011.

Haws LC, Fitzgerald LBurkhalter B, Harris M, Wikoff DS. 2011. Assessment of the US EPA’s proposed toxicological values for TCDD for regulation of dioxin-like compounds in foods: Bridging the science divide in a global market. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Troyano E, McMillan D, Sarlo K, Li L, Wimalasena R. 2011. Approach to assessing consumer safety of botanical ingredients with emphasis to type 1 allergy. In: Dayan N, Kromidas L (eds), Formulating, Packaging, and Marketing of Natural Cosmetic Products, 1st Ed. John Wiley & Sons, Hoboken, NJ, USA, doi: 10.1002/9781118056806.ch9.

Gujral JS, Proctor DM, Su SH, and Fedoruk JM. 2011. Water adherence factors for human skin. Risk Analysis 31(8):1271-1280.

View Abstract

Rowlands JC, Urban J, Wikoff DS, Budinsky R. 2011. The presence and estimated functional effect of single nucleotide polymorphisms at the AIP, ARNT, HSP90AA1, AND HSP90AB1 loci in the human population. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Kreider ML, Panko JM, McDonald JD, McAtee BL, Finley BL, Seagrave J. Effects of intratracheal instillation of tire and road wear particles (TRWP) and tread particles (TP) on inflammation and cytotoxicity in rat lung: A comparative toxicity study. Society of Toxicology Annual Meeting, Baltimore, MD, March 2011.

Grespin ME, Le MH, Panko JM. Safety data sheet alteration during alignment with the Globally Harmonized System of Classification (GHS) and implications for chemical manufacturers, suppliers and distributors. Society for Risk Analysis Annual Meeting, Charleston, SC, December 2011.

Hitchcock KM, Panko JM, Scott PK. The chemical footprint: An emerging indicator of environmental performance. Society for Environmental Toxicology and Chemistry, Boston, MA, November 2011.

Gaffney SH, Panko JM, Unice KM, Burns AM, Kreider ML, Gelatt RH, Booher LE, Paustenbach DJ. 2011. Occupational exposure to benzene at the ExxonMobil refinery in Baytown, TX (1978-2006). J Exp Sci Environ Epidemiol 21:169–185.

View Abstract

Marwood C, McAtee BL, Kreider ML, Ogle RS, Finley BL, Sweet LI, Panko JM. 2011. Acute aquatic toxicity of tire and road wear particles to alga, daphnid and fish. Ecotoxicology 20:2079, doi: 10.1007/s10646-011-0750-x.

View Abstract

Panko JM, Hitchcock KM. 2011. Chemical footprint: Enduring product sustainability. EM: AWMA Magazine for Environ Managers, December:12–15.

View Abstract

Thomas RS, Rowlands JC, Budinsky RA, Thompson CM, Urban JD. Dombkowski, A. 2011. Genomic approaches for relative potency assessment. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Lau A,* Zhang DD.* The Nrf2-Keap1-ARE signaling pathway: dual roles of Nrf2 in cancer. Abstract for poster presentation, University of Arizona, Department of Pharmacology and Toxicology Student Recruitment, Tucson, AZ, February 2011.

Lau A,* Wang SJ, Zhang DD. Arsenic activates the Nrf2 antioxidant response pathway via autophagy. Abstract for poster presentation, Undergraduate and Oxidative Stress and Redox Biology Poster Sessions, 50th Annual Meeting and ToxExpo of the Society of Toxicology, Washington, DC, March 2011.

Lau A, Whitman SA, Wang H, Zhang DD.* The protective role of Nrf2 in arsenic-induced toxicity and carcinogenicity. Abstract for poster presentation, Outstanding New Environmental Scientist Symposium, National Institute of Environmental Health Sciences, Research Triangle Park, NC, July 2011.

Lau A,* Wang XJ, Zhang DD. Arsenic activates the Nrf2 antioxidant response pathway via autophagy. Abstract for poster presentation, Arizona Health Science Center Frontiers in Biomedical Research Poster Forum, Tucson, AZ, November 2011.

Lau A,* Wang H, Zhang DD. Arsenic and Nrf2: What’s p62 got to do with it? Abstract for poster presentation, 2011 Student Showcase, Biological Sciences category, Tucson, AZ, November 2011.

Lau A,* Wang H, Zhang DD. Arsenic induces chronic Nrf2 activation. Abstract for poster presentation, American College of Toxicology, 32nd Annual Meeting of the American College of Toxicology, Phoenix, AZ, November 2011.

View Abstract

Ren D, Villeneuve NF, Jiang T, Wu T, Lau A, Toppin HA, Zhang DD. 2011. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Proc Nat Acad Sci USA 108:1433–1438, doi:10.1073/pnas.1014275108.

View Abstract

Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD. 2011. KPNA6 (Importin{alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response. Mol Cell Biol 31(9):1800–1811, doi: 10.1128/MCB.05036-11.

View Abstract

Beyer BK, Chernoff N, Danielsson BR, Davis K -Bruno, Harrouk W, Hood RD, Janer G, Wändel Liminga U, Kim J, Rocca M, Rogers JM, Scialli AR. 2011. Maternal toxicity and its impact on study design and data interpretation. Birth Defects Res, Part B, Dev Reprod Toxicol 92:36–51.

View Abstract

Grace CE, Kim SJ, Rogers JM. 2011. Maternal influences on epigenetic programming of the developing hypothalamic-pituitary-adrenal axis. Birth Defects Res, Part A, Clin Mol Teratol 91:797–805.

View Abstract

Lau C, Rogers JM, Desai M, Ross MG. 2011. Fetal programming of adult disease: Implications for prenatal care. Obstet Gynecol 117:978–985.

View Abstract

Rowlands JC, Urban JD, Wikoff DS, Budinsky RA. 2011. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene. Drug Metab Pharmacokinet 26(4):431-439.

View Abstract

Wikoff DS, Thompson C, Walker N, DeVito M, Harris M, Birnbaum L, Haws L. 2011. Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Datta T, Racz L, Kotay SM, Goel R. 2011. Seasonal variations of nitrifying community in trickling filter-solids contact (TF/SC) activated sludge systems. Bioresource Technol 102(3):2272–2279.

View Abstract

Sheehan PJ, Brorby GP, Berman DW, Bogen KT, Holm SE. 2011. Chamber for testing asbestos-containing products:  Validation and testing of a re-created chrysotile-containing joint compound.  Ann Occup Hyg 55(7):797-809.

View Abstract

Budinsky R, Urban J, Rowlands JC. 2011. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator gene. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Ceder R, Merne M, Nilsson J-A, Staab C, Höög J-O, Thompson CM, Grafström RC. 2011.  Toxicogenomic profiling of formaldehyde-exposed normal and transformed human oral keratinocytes. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Fitzgerald LBurkhalter B, Urban J, Staskal D, Harris M, Haws L. 2011. VOC serum levels in the general U.S. population: An analysis of the 2003-2004 NHANES dataset. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Po IP, DeSantis AS, Hahn RA, Gerecke DR, Laskin JD, Gordon MK. 2011. Comparison of corneal wound healing after ultraviolet and nitrogen mustard injury. Society of Toxicology, Abstract #2024.

DeSantis AS, Hahn RA, Heindel AD, Svoboda KKH, Gerecke DR, Gordon MK. 2011. Nitrogen mustard-induced corneal injury is ameliorated by ADAM17/TACE inhibitors. Society of Toxicology, Abstract #2023.

DeSantis AS, Po IP, Hahn RA, Svoboda KKH, Gordon MK. 2011. SPARC and Hevin in corneal healing after nitrogen mustard and UVB injury. FASEB J.

DeSantis AS, Hahn RA, Gerecke DR, Svoboda KKH, Gordon MK. 2011. Inhibition of ERK attenuates ADAM17 activation in nitrogen mustard-induced corneal injuries. Association for Research in Vision and Ophthalmology (ARVO) Program #2044.

Haws L, Proctor D, Thompson C, Harris M. 2011. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Tichomirowa MA, Bariler A, Daly AF, Jaffrain-Rea M-L, Ronchi CL, Yaneva M, Urban JD, Petrossians P, Elenkova AP, Tabarin A, Desailloud R, Maiter D, Schürrmeyer T, Cozzi R, Theodoropoulou M, Sievers C, Bernabeu I, Naves LA, Chabre O, Fajardo Montañana C, Hana V, Halaby G, Delemer B, Labarta JI, Sonnet E, Ferrandez A, Hagelstein MTS, Caron P, Stalla GK, Bours V, Zacharieva S, Spada A, Brue T, Beckers A. 2011. High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas. Eur J Endocrinol 165(4):509-515.

View Abstract

Urban JD, Rowlands JC, Budinsky RA. 2011. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene. Drug Metab Pharmacokinet 26(6):637-645.

View Abstract

Henderson RG, Cappellini D, Seilkop S, Oller A, Bates H. 2011. Bioaccessibility-based read-across assessment of nickel compounds for oral systemic toxicity. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Wilson VS, Keshava N, Hester S, Segal D, Chiu W, Thompson CM, Euling SY. 2013. Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment. Toxicol Appl Pharmacol 271:299–308.

View Abstract

Kim S, Thompson CM, Kopec AK, Harris MA, Zacharewski TR. 2011. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Proctor D, Haws L,Thompson C, Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, 2011. Washington, D.C.

View Abstract

Proctor D, Meek B. 2011. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Staskal-Wikoff D, Budinsky R, Rowlands JC. 2011. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Franke K, Paustenbach D. 2011. Government and Navy knowledge regarding health hazards of asbestos: A state of the science evaluation (1900 to 1970). Inhal Toxicol 23(S3):1–20.

View Abstract

2010

Anumolu SS, DeSantis AS, Menjoge AR, Hahn RA, Beloni JA, Gordon MK, Sinko PJ. 2010. Doxycycline loaded poly(ethylene glycol) hydrogels for healing vesicant-induced ocular wounds. Biomaterials 31(5):964–974.

View Abstract

Gordon MK, DeSantis AS, Deshmukh M, Lacey CJ, Hahn RA, Beloni JA, Anumolu SS, Schlager JJ, Gallo MA, Heindel N, Gerecke DR, Sinko PJ, Svoboda KKH, Babin M. 2010. Doxycycline hydrogels as a potential therapy for ocular vesicant injury. J Ocul Pharmacol Therapeut 26:407–419.

View Abstract

Harris M, Tachovsky JA, Staskal-Wikoff D, Aylward L, Burkhalter B, Simon T, Haws L. 2010. Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Johns DO, Owens EO, Thompson CM, Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.

View Abstract

Harris M, Tachovsky JA, Staskal-Wikoff D, Simon T, Burkhalter B, Urban J, Haws L. 2010. Assessment of the impact of various soil cleanup levels on serum concentrations of dioxin-like compounds in humans. Presented at the 49th Annual Meeting of Society of Toxicology. March 7-11, Salt Lake City, Utah.

Birnbaum LS, Staskal-Wikoff D. 2010. 5th International PCB Workshop–Summary and implications. Environ Int 36(8):814-818.

View Abstract

Haws L. 2010. Biomonitoring – A tool for assessing community exposures to air toxics. Presented at the Air Quality 2010 conference, hosted by the University of Texas School of Law,  November 19.

Gatto NM, Kelsh MA, Mai DH, Suh M, Proctor DM. 2010. Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis. Cancer Epidemiol 34(4):388-99.

View Abstract

Haws L, Tachovsky JA, Staskal-Wikoff D, Aylward L, Burkhalter B, Urban J, Simon T, Harris M. 2010. An evaluation of the influence of different soil cleanup levels on the concentration of dioxin-like compounds in human serum. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Haws L. 2010. Biomonitoring: The circle of life. Presented in the Oil and Gas special session, at the 22nd Annual Texas Environmental Superconference, August 5-6, Austin, TX.

Rowlands CJ, Staskal DF, GollapudI B, Budinsky R. 2010. The Human AHR: Identification of single nucleotide polymorphisms from six ethnic populations. Pharmacogenet Genomics 20(5):283-290.

View Abstract

Panko JM, Kreider ML, Ferrara J. REACH – A review of the regulation and technical components of registration. AIHA Pittsburgh Section, Pittsburgh, PA, February 28, 2010.

Kreider ML, Panko JM, McAtee BL, Sweet LI, Finley BL. 2010. Physical and chemical characterization of tire-related particles: Comparison of particles generated using different methodologies. Sci Total Environ
408(3):652–659.

View Abstract

Gaffney SH, Burns AM, Kreider ML, Unice KM, Widner TE, Paustenbach DJ, Booher LE, Gelatt RN, Panko JM. 2010. Occupational exposure at the ExxonMobil refinery in Beaumont, TX (1976-2007). Int J Hyg Environ Health 213(4):285–301.

View Abstract

Staskal-Wikoff D, Burkhalter B, Stapleton H, Harris M. 2010. PBDEs in Newark Bay sediments. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Sheehan P, Bogen KT, Hicks J, Goswami E, Brorby G, Lau E, Ott B.  2010. Benzene inhalation of parts washers:  New estimates based on measures of occupational exposure to solvent coaromatics.  Risk Analysis 30(8):1249–1267.

View Abstract

Rish W. 2010. Practical aspects of risk assessment for Brownfield development. Chapter 25 in Davis T (ed.), Brownfields, Third Edition. American Bar Association.

Lau A,* Zhang DD.* The Nrf2-Keap1-ARE signaling pathway: Dual roles of Nrf2 in cancer. Abstract for poster presentation, University of Arizona, Department of Pharmacology and Toxicology Student Recruitment, Tucson, AZ, February 2010.

Lau A,* Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. p62 sequesters Keap1 into autophagosomes, preventing the Keap1-dependent ubiquitination and degradation of Nrf2. Abstract for poster presentation, 49th Annual Society of Toxicology Meeting, Salt Lake City, UT, March 2010.

Lau A,* Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. A novel mechanism of Nrf2 activation by autophagy deficiency: A direct interaction between Keap1 and p62. Abstract for poster presentation, Keystone Symposia, Cell Death Pathways: Apoptosis, Autophagy, and Necrosis, Vancouver, B.C., Canada, March 2010.

Lau A,* Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. A novel mechanism of Nrf2 activation by autophagy deficiency: A direct interaction between Keap1 and p62. Abstract for poster presentation, International Conference on Frontiers in Biomedical and Environmental Health Sciences, Beijing, China, May 2010.

Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. 2010. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: Direct interaction between Keap1 and p62. Mol Cell Biol 30:3275–3285, doi:10.1128/MCB.00248-10.

View Abstract

Babic A, Loftin IR, Stanislaw S, Wang M, Miller R, Warren SM, Zhang W, Lau A, Miller M, Wu P, et al. 2010. The impact of pre-analytical processing on staining quality for H&E, dual hapten, dual color in situ hybridization and fluorescent in situ hybridization assays. Methods 52:287–300, doi: 10.1016/j.ymeth.2010.08.012.

View Abstract

Villeneuve NF, Lau A, Zhang DD. 2010. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: An insight into cullin-ring ubiquitin ligases. Antiox Redox Signal 13:1699–1712, doi:10.1089/ars.2010.3211.

View Abstract

Chernoff N, Rogers JM. 2010. Hypoxia and the edema syndrome: Elucidation of a mechanism of teratogenesis. Birth Defects Res B Dev Reprod Toxicol 89:300–303.

View Abstract

Shepard TH, Barr M Jr, Brent RL, Hendrickx A, Kochhar D, Oakley G, Scott WJ Jr, Rogers JM. 2010. An updated history of the Teratology Society. Birth Defects Res A Clin Mol Teratol 88:263–285.

View Abstract

Daston GP, Chapin R, Scialli AR, Piersma AH, Carney EW, Rogers JM, Friedman JM. 2010. A different approach to validating screening assays for developmental toxicity. Birth Defects Res, Part B, Dev Reprod Toxicol 89:526–530.

View Abstract

Tachovsky JA, Haws L. 2010. Application of principal components analysis and sequential gaussian simulation to a comprehensive soil sampling dataset to predict PCDD/F concentrations in Midland, MI. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Tachovsky JA, Urban JDWikoff DSHaws LC, Harris MA. 2010. Reduction of a large fish tissue analyte database: identifying and assessing data specific to a remediation site for risk assessment application. Chemosphere 80(5):481-488.

View Abstract

Racz L, Datta T, Goel RK. 2010. Organic carbon effect on nitrifying bacteria in a mixed culture. Water Sci Technol 61(11):2951–2956.

View Abstract

Racz L, Goel RK. 2010. Fate and removal of estrogens from municipal wastewater. J Environ Monit 12(1):58–70.

View Abstract

Racz L, Datta T, Goel RK. 2010. Effect of organic carbon on ammonia oxidizing bacteria in a mixed culture. Bioresource Technol 101(16):6454–6460.

View Abstract

Thompson CM, Grafström RC. 2010. Considerations for the implausibility of leukemia induction by formaldehyde. Toxicol Sci 120(1):230-232.

View Abstract

Waters MD, Jackson MA, Lea IA. 2010. Characterizing and predicting carcinogenicity and mode-of-action using conventional and toxicogenomics methods. Mutat Res 705(3):184–200.

View Abstract

Tachovsky A, Staskal DUrban J, Harris MA, Haws L. 2010. Assessment of environmental data collected in a community with numerous petroleum refining and petrochemical facilities. Presented at the 49th Annual Meeting of Society of Toxicology. March 7-11, Salt Lake City, Utah.

Thompson CM, Ceder R, Grafström RC. 2010. Formaldehyde dehydrogenase: Beyond phase I metabolism. Toxicol Lett 193(1):1-3.

View Abstract

DeSantis AS; Beloni J, Hahn RA, Gerecke DR, Babin M, Gordon MK. 2010. The cosmeceutical amino-plex ameliorates mustard-induced corneal injury. Society of Toxicology, Abstract #347.

DeSantis AS, Hahn RA, Beloni JA, Gerecke DR, Svoboda KKH, Gordon MK. 2010. ADAM17/TACE inhibitors attenuate vesicant-induced epithelial-stromal separations. Association for Research in Vision and Ophthalmology (ARVO), Program #4783 (oral presentation).

DeSantis AS, Hahn RA, Gallo MA, Gerecke DR, Babin MC, Gordon MA. 2010. Amino plex as a countermeasure against vesicant exposure of rabbit corneas. 17th Biennial Medical Defense Bioscience Review meeting (May 2010, Hunt Valley, MD). In: Proceedings of the US Army Medical Defense Bioscience Review: A095.

Tachovsky JA, Haws L. 2010. Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI. Presented at the Society for Risk Analysis annual meeting, December 5-8, Salt Lake City, UT.

Urban JD, Tachovsky JA, Haws LC, Wikoff Staskal D, Harris MA. 2010. Response to Mugdan et al.’s comment on Urban et al. “Assessment of Human Health Risks Posed by Consumption of Fish from the Lower Passaic River, New Jersey.” Sci Tot Environ 408(6):1468-1470.

View Abstract

Urban J, Burkhalter B, Tachovsky JA, Haws L, Harris M. 2010. Evaluation of polychlorinated naphthalenes (PCNs) in Newark Bay sediment. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Urban JD, Tachovsky JA, Haws LC, Staskal DF, and Harris MA. 2010. Response to Buchanan et al.’s comment on Urban et al. “Assessment of Human Health Risks Posed by Consumption of Fish from the Lower Passaic River, New Jersey.” Sci Tot Environ 408(8):2004-2007.

View Abstract

Driscoll SK, McArdle ME, Plumlee MH and Proctor D. 2010. Evaluation of hexavalent chromium in sediment pore water of the Hackensack River, New Jersey, USA. Environ Toxicol Chem 29(3):617-20.

View Abstract

2009

Haws LC, DeVito MJ, Walker NJ, Birnbaum LS, Farland WH, Harris MA, Tachovsky JA, Unice KM, Scott PK, Staskal-Wikoff DF. 2009. Development of distributions of relative potency estimates to quantitatively assess uncertainty inherent in the TEFs for dioxin-like compounds: A proposed consensus-based weighting. Presented at Dioxin 2009, Beijing, China.

Guzelian PS, Victoroff MS, Halmes C,  James RC. 2009. Clear path: Towards an evidence-based toxicology (EBT). Human & Exp Toxicol 28:71-79.

View Abstract

Staskal-Wikoff DFHarris MAHaws LC, Birnbaum LS, Tachovsky JA. 2009. Probabilistic evaluation of cancer and non-cancer risk associated with exposure to BDE 209 in automobiles. Presented at Dioxin 2009. Beijing, China.

Oller AR, Cappellini D, Henderson RG, Bates HK. 2009. Temperature effect on nickel release in ammonium citrate.  J Environ Monit 11(9):1697-1699.

View Abstract

Urban JD, Tachovsky JA, Staskal DF, Haws LC, Harris MA. 2009. Human health risk assessment of consumption of fish from the Lower Passaic River. Presented at the 48th Annual Meeting of Society for Toxicology, March 15-19, Baltimore, MD.

Oller AR, Cappellini D, Henderson RG, Bates HK. 2009. Comparison of nickel release in solutions used for the identification of water-soluble nickel exposures and in synthetic lung fluids. J Environ Monit 11(4):823–829.

View Abstract

Vivanco S. Spatial relationship between pediatric asthma, asthma risk factors and diesel pollutants. Presentation to Annual Biomedical Research Conference for Minority Students, Phoenix, AZ, 2009.

Menzie CA, Ziccardi LM, Lowney YW, Fairbrother A, Shock SS, Tsuji JS, Hamai D, Proctor D, et al. 2009. Importance of considering the framework principles in risk assessment for metals. Environ Sci Technol 43(22):8478-8482.

View Abstract

Scott, LLF, Staskal, DF, Williams ES, Luksemburg WJ, Urban JD, Nguyen LM, Haws LC, Birnbaum LS, Paustenbach DJ, Harris MA. 2009. Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in southern Mississippi catfish and estimation of potential health risks. Chemosphere 74(7):1002-10.

View Abstract

Panko JM. Case studies in sustainable packaging. Session: What’s in Your Package? Sustainable Packaging Coalition Conference, Chicago, IL, March 25, 2009.

Panko JM. Progress on a BEEL Guide for d-limonene. Roundtable #224, American Industrial Hygiene Conference and Exhibition, Toronto, ON, June 1–4, 2009.

Widner TE, Paustenbach DJ, Gaffney SH, Panko JM, Unice KM, Burns AM, Kreider ML, Gelatt R, Booher L. Airborne benzene concentrations associated with dock operations at the ExxonMobil Refinery, Baytown, Texas (1978–2007). Presentation #243, American Industrial Hygiene Conference and Exhibition, Toronto, ON, June 1–4, 2009.

Panko JM, McAtee BL, Kreider ML, Gustafsson M, Blomqvist G, Gudmundsson A, Sweet LI, Finley BL. Physio-chemical analysis of airborne tire wear particles. Eurotox 2009, Dresden, Germany, September 2009.

McAtee BL, Kreider ML, Panko JM, Sweet LI, Finley BL. Biological leaching of metals from respirable tire wear particles. Eurotox 2009, Dresden, Germany, September 2009.

Panko JM, Gaffney SH, Kreider ML, Unice KM, Burns AM, Paustenbach DJ, Booher LE, Gelatt RH. Job and task based analysis of benzene air concentrations associated with refinery operations. Benzene 2009: Health Effects and Mechanisms of Bone Marrow Toxicity; Implications for t-AML and the Mode of Action Framework, Munich, Germany, September 2009.

Unice KM, Kreider ML, McAtee BL, Panko JM. Evaluation of extractable organic zinc as a quantitative marker for tire tread particles in environmental matrices. ACS Rubber Division 176th Technical Meeting, Pittsburgh, PA, October 2009.

Harada M, Shibata T, Panko JM, Unice KM. Analysis methodology of rubber fraction in fine particles. ACS Rubber Division 176th Technical Meeting, Pittsburgh, PA, October 2009.

Williams ES, Panko JM, Paustenbach DJ. 2009. The European Union’s REACH Regulation: A review of its history and requirements. Crit Rev Toxicol 39(7):553–575.

View Abstract

Panko JM, Gaffney SH, Burns AM, Unice KM, Kreider ML, Booher LE, Gelatt RH, Marshall JR, Paustenbach DJ. 2009. Occupational exposure to benzene at the ExxonMobil Refinery at Baton Rouge, Louisiana (1977–2005). J Occup Environ Hyg 6:517–529.

View Abstract

Thompson CM, Grafstrom RC. 2009. Commentary: Mechanistic considerations for associations between formaldehyde exposure and nasopharyngeal carcinoma. Environ Health 8:53.

View Abstract

Lau A,* Wang XJ, Zhang DD. Arsenic induces autophagy and upregulates the Nrf2-dependent antioxidant response pathway through p62. Abstract for oral presentation, 27th Annual regional Chapter Meeting of the Mountain West Society of Toxicology, Albuquerque, NM, September 2009.

Lau A,* Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. p62 sequesters Keap1 into autophagosomes, preventing the Keap1-dependent ubiquitination and degradation of Nrf2. Abstract for poster presentation, 3rd Biennial Research Frontiers in Nutritional Science Conference, Tucson, AZ, November 2009.

Thompson CM, Sonawane B, Grafström RC. 2009. The ontogeny, distribution and regulation of alcohol dehydrogenase 3: Implications for pulmonary physiology. Drug Metab Disposit 37(8):1565-1571.

View Abstract

Thompson CM, Johns DO, Sonawane S, Barton HA, Hattis D, Tardif R, Krishnan K. 2009. Database for physiologically based pharmacokinetic (PBPK) modeling: Physiological parameters for healthy and health-impaired elderly. J Toxicol Environ Health, Part B 12:1–24.

View Abstract

Lea IA, Jackson MA, Dunnick JK. 2009. Genetic pathways to colorectal cancer. Mutat Res 670(1–2):96–98.

View Abstract

Urban, JD, Tachovsky JA, Staskal DF, Haws LC, Harris MA. 2009. Assessment of human health risks posed by consumption of fish from the Lower Passaic River, New Jersey. Sci Total Environ 408(2):209-224.

View Abstract

DeSantis AS, Hahn RA, Beloni J, Svoboda KKH, Gerecke DR, Babin M, Gordon MK. 2009. Countermeasures against nitrogen mustard injury to the cornea. Society of Toxicology, Abstract #547.

Hahn RA, Schlager J, DeSantis AS, Gallo M, Heck D, Sinko P, Laskin DL, Laskin JD, Heindel D, Gerecke DR, Babin M, Gordon MK. 2009. Electron microscopy shows that the effect of half mustard on the corneal basement membrane zone is ameliorated by doxycycline and Tobradex treatment. Society of Toxicology, Abstract #549.

Shakarjian MP, Vetrano AM, Gray JP, DeSantis AS, Riley DJ, Laskin JD, Chang Y, Gerecke DR, Heck DE. 2009. Sulfur mustard (SM) analogs alter keratinocyte viability and interact with basement membrane (BM) components. Society of Toxicology, Abstract #552.

DeSantis AS, Hahn RA, Beloni JA, Schultz G, Heindel N, Svoboda KKH, Babin MC, Gerecke DR, Gordon MK. 2009. Healing of corneal wounds induced by vesicants. FASEB J. 23:469.2.

DeSantis AS, Hahn RA, Beloni J, Gerecke DR, Svoboda KKH, Gordon MK, Schultz G. 2009. Corneal vesicant injury is ameliorated by matrix metalloproteinase inhibitors. Association for Research in Vision and Ophthalmology (ARVO), Program #3064 (oral presentation).

2008

Harris MA, Shay E, Unice KM, Scott LF, Haws LC. 2008. Preliminary evaluation of health risks posed by PCDD/Fs and PCBs from the ingestion of fish from the Lower Passaic River. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Proctor, D. 2008Hexavalent chromium. In: Encyclopedia of Quantiative Risk Analysis and Assessment, Melnick E, Everitt B. (eds.). Wiley.

Harris MATachovsky JA, Williams ES, Paustenbach DP, Haws LC. 2008. Assessment of the health risks posed by benzene in soft drinks. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

DeWoskin RS, Thompson CM. 2008. Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants. Regul Toxicol Pharmacol 51:66–86.

View Abstract

Boice JD Jr, Cohen SS, Mumma MT, Chadda B, Blot WJ. 2008. A cohort study of uranium millers and miners of Grants, New Mexico, 1979-2005. J Radiol Prot 28(3):303-325.

View Abstract

Haws LC, Unice KM, Tachovsky AT, Harris MA, DeVito MJ, WalkerNJ, Birnbaum LS, Farland WH, Nguyen L, Staskal DF. 2008. Assessment of the impact of using weighted distributions of REPs to develop exposure estimates for dioxin-like compounds. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Donovan E, Unice K, Roberts JD, Harris M, Finley B. 2008. Risk of gastrointestinal disease associated with exposure to pathogens in the water of the Lower Passaic River. Appl Environ Microbiol 74:994-1003.

View Abstract

Ulrich K, Hincks JS, Walsh R, Caroline Wetterstrand EM, Fidock MD, Sreckovic S, Lamb DJ, Douglas GJ, Yeadon M, Perros-Huguet C, Evans SM. 2008. Anti-inflammatory modulation of chronic airway inflammation in the murise house dust mite model. Pulmon Pharmacol Therapeut 21(4):637–647.

View Abstract

Haws LC, DeVito MJ, Walker NJ, Birnbaum LS, Unice KM, Scott PK, Harris MATachovsky A, Farland WH, Finley BF,  Staskal DF. 2008. Development of weighted distributions of REPs for dioxin-like compounds: Implications for risk assessment. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

Donovan EP, Staskal DF, Unice KM, Roberts JD, Haws LC, Finley BL, and Harris MA. 2008. Risk of gastrointestinal disease associated with exposure to pathogens in the sediments of the Lower Passaic River. Appl Environ Microbiol 74:1004-1018.

View Abstract

Gerlach RW, Barker ML, Sagel PA, Ralston CS, McMillan DA. 2008. In-use peroxide kinetics of 10% hydrogen peroxide whitening strips. J Clin Dent 19(2):59-63.

View Abstract

Haws LCTachovsky JA, Williams ES, Scott LF, Paustenbach D, Harris MA. 2008. Assessment of potential human health risks posed by benzene in beverages. J Food Sci 73(4):T33-T41.

View Abstract

Scott LLF, Staskal DFHarris MA, Finley BL, Haws LC. 2008. Evaluation of dioxin-like compounds in workers from a primary magnesium production facility relative to levels observed in the general US population. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

Panko JM, Gaffney SH, Unice KM, Kreider ML, Burns AM, Widner TE, Booher LE, Gelatt GL, Paustenbach DJ. Benzene exposures of refinery workers: Baytown, TX (1978-2006). American Industrial Hygiene Conference and Exhibition, June 2008.

Kreider ML, McAtee BL, Sweet LI, Panko JM, Finley BL. Physical and chemical characterization of tire-related particles: Comparison of particles generated using different methodologies. Paper #41, Fall 174th Technical Meeting of the Rubber Division of the American Chemical Society, Louisville, KY, October 2008.

Panko JM, Kreider ML, Sweet LI, McAtee BL, Finley BL. Methods for collecting tire wear particles. Paper #40, Fall 174th Technical Meeting of the Rubber Division of the American Chemical Society, Louisville, KY, October 2008.

Gaffney SH, Kreider ML, Unice KM, Burns AM, Paustenbach DJ, Booher LE, Gelatt RH, Panko JM. Benzene exposure in refinery workers (1976-2006). Abstract #864, International Society for Environmental Epidemiology & International Society of Exposure Analysis 2008 Joint Annual Conference, Pasadena, CA, October 12–16, 2008.

James HR, Barfield L, Britt JK, James RC. 2008. Worker exposure to secondhand smoke: Evaluating a prediction model. Prof Saf Sep:34-44.

View Abstract

Staskal DF, Donovan EP, Haws LC, Roberts JD, Unice KM, Finley BL, Harris MA. 2008. Human health risks associated with exposure to pathogens in waters and sediments of the Lower Passaic River. Presented at the Society of Toxicology Annual Meeting. March 16-20, Seattle, WA.

Lau A, Villeneuve NF, Sun Z, Wong PK, Zhang DD. 2008. Dual roles of Nrf2 in cancer. Pharmacol Res 58:262–270, doi: 10.1016/j.phrs.2008.09.003.

View Abstract

Makris SL, Thompson CM, Euling SY, Selevan SG, Sonawane B. 2008. A lifestage-specific spproach to hazard and dose-response characterization for children’s health risk assessment. Birth Defects Res Part B 83:530–546.

View Abstract

Staskal DF. 2008. Roundtable: Case study on the risks and benefits of DecaBDE, a major brominated flame retardant. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

Richardson VM, Staskal DF, Ross DG, Diliberto JJ, Devito MJ, Birnbaum LS. 2008. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicol Appl Pharmacol 226(3):244-250.

View Abstract

Staskal DFTachovsky JAHarris MAHaws LC. 2008. Preliminary evaluation of human health risk associated with exposure to PBDEs in the United States. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Scott LLF, Harris MA, Unice KM, Scott P, Nguyen LM, Haws LC, and Paustenbach D. 2008. Addendum to: Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States population. J Exp Sci Env Epidemiol 18(5):524-532.

View Abstract

Tachovsky JAHarris MAStaskal DF, Scott LF, Luksemburg WJ, Paustenbach DP, Haws LC. 2008. Analysis of fish tissue concentrations of dioxins and furans using principal components analysis. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Scott PK, Proctor D. 2008. Soil suspension/dispersion modeling methods for estimating health-based soil cleanup levels of hexavalent chromium at chromite ore processing residue sites. J Air Waste Manag Assoc 58(3): 384-403.

View Abstract

Tachovsky JAStaskal DFHarris MA, Scott LF, Luksemburg WJ, Paustenbach DP, Haws LC. 2008. Principal components analysis of PBDE concentrations in fish tissue from southern Mississippi. Presented at Dioxin 2008, August 17-22, Birmingham, England.

DeSantis AS, Hahn RA, Beloni JA, Gerecke DR, Gordon MK. 2008. An organ culture system for studying corneal wound healing. FASEB J 22:582.3 (oral presentation).

DeSantis AS, Hahn RA, Beloni J, Gerecke DR, Svoboda KKH, Gordon MK. 2008. Doxycycline promotes healing of corneal injuries induced by half mustard (CEES). Association for Research in Vision and Ophthalmology (ARVO), Program #3386.

Staskal DF, Scott LLF, Haws LC, Luksemburg WJ, Birnbaum LS, Nguyen LM, Urban JD, Williams ES, Paustenbach DJ, Harris MA. 2008. Assessment of polybrominated diphenyl ether exposures and health risks associated with consumption of southern Mississippi catfish. Environ Sci Technol 42(17):6755-6761.

View Abstract

Urban JDHaws LCStaskal DF, Scott LF, Scott PS, Tachovsky AT, Unice KM, Harris MA. A framework for evaluating serum dioxin data derived from biomonitoring studies. Presented at Dioxin 2008, August 17-22, 2008. Birmingham, England.

Subramaniam RP, Chen C, Crump KS, Devoney D, Fox JF, Portier CJ, Schlosser PM, Thompson CM, White P. 2008. Uncertainties in biologically-based modeling of formaldehyde-induced respiratory cancer risk: Identification of key issues. Risk Analysis 28(4):907–923.

View Abstract

Thompson CM, Subramaniam RP, Grafström RC. 2008. Mechanistic and dose considerations for supporting adverse pulmonary physiology in response to formaldehyde. Toxicol Appl Pharmacol 233(3):355–359.

View Abstract

Thompson CM, Sonawane B, Barton HA, DeWoskin RS, Schlosser P, Lipscomb JC, Chiu W, Krishnan K. 2008. Approaches for applications of physiologically based pharmacokinetic models in risk assessment. J Toxicol Environ Health, Part B 11(7):519–547.

View Abstract

Williams CW, Perry CS. 2008. Risk assessment for arsenic on indoor surfaces. Presented at the Society for Risk Analysis annual meeting, December 7-10, Boston, MA.

DeSesso JM, Watson RE, Keen CL, Hazelden KP, Haws LC, Li AA. 2008. Analysis and integration of developmental neurotoxicity and ancillary data into risk assessment: A case study of dimethoate. J Toxicol Environ Health A 72(2):94-109.

View Abstract

2007

Ferriby LL, Knutsen JS, Harris MA, Unice KM, Scott P, Nony P, Haws LC, and Paustenbach D. 2007. Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States Population. J Exp Sci Environ Epidemiol 17:358-371.

View Abstract

Britt, J.K. and R.C. James. Toxicology. In: Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc., Hoboken, NJ. pp. 201-252,  2007.

Proctor DM, Gatto NM, Hong SJ, Allamneni KP. 2007. Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment. Toxicol Sci. 98(2):313–326.

View Abstract

DeSesso, J., R.E. Watson, C.L. Keen, K.P. Hazleden, L.C. Haws, and A.A. Li. 2007. Integration of Developmental Toxicity Data into Risk Assessment: A Case Study of Dimethoate. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Staskal, D.F., and L.S. Birnbaum. 2007. Brominated Flame Retardants, Maxcy-Rosenau Public Health and Preventive Medicine, 15th Edition.

Diliberto, J.J., D.F. Staskal, H. Hakk, and L.S. Birnbaum. 2007. Differential urinary protein binding of PBDEs in mice. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Booker DL, Bowman LA, Fiedler SK, McMillan DA, Barker ML, Farrell S. 12-Month clinical safety of 6% hydrogen peroxide strips used daily. J Dent Res 86 (Abstract 2668), 2007.

Dwyer, M., Perry, C., and Jenkins, A. Trichloroethylene toxicity and risks: recent developments and potential implications. Presented at February 2007 Texas Association of Environmental Professionals — Environmental Challenges and Innovations Conference.

Simon T, Britt JK and James RC. 2007. Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures. Regul Toxicol Pharmacol 48:148-170.

Emond, C., J. Raymer, E. Garner, J. Diliberto, D. Staskal, and L.S. Birnbaum. 2007. A physiologically-based pharmacokinetic model for developmental exposure to PBDE-47 in rodents. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Panko JM, Unice KM, Shay EC. Javier AF. Assessment of children’s exposures to toluene. Society of Toxicology Conference, March 2007.

Gaffney SH, Widner TE, Paustenbach DJ, Panko JM, Brown JL, Unice KM. Historical benzene exposure reconstruction: Refinery workers at ExxonMobil Refinery, Baton Rouge, Louisiana (1978-2005). American Industrial Hygiene Conference and Exhibition, June 2007.

Williams PRD, Panko JM, Unice KM, Brown JL, Paustenbach DJ. 2007. Benzene exposures from petroleum-derived solvents containing trace levels of benzene in occupational settings. American Industrial Hygiene Conference and Exhibition, June 2007.

Panko JM, Unice KM, Shay EC. 2007. Recommendations for developing child-focused exposure assessments based on VCCEP experiences. Society for Risk Analysis, December 2007.

Paustenbach DJ, Panko JM, Scott PK, Unice KM. 2007. A methodology for estimating human exposure to perfluorooctanoic acid (PFOA): A retrospective exposure assessment of a community (1951-2003). J Toxicol Environ Health A 70(1):28–57.

View Abstract

Scott PK, Unice KM, Williams S, Panko JM. 2007. Statistical evaluation of metal concentrations as a method for identifying World Trade Center dust in buildings. Environ Forensics 8(4).

View Abstract

Paustenbach DJ, Gaffney SH, Scott PK, Brown JL, Panko JM. 2007. Commentary: High background levels of urinary benzene metabolites found in a volunteer study. J Occup Environ Hyg 4:D71–D77.

Thompson CM and Grafström RC. 2007. Mechanistic considerations for formaldehyde-induced bronchoconstriction involving S-nitrosoglutathione reductase. J Toxicol Environ Health, Part A 71, 244–248.

Ferriby, L.L., M.A. Harris, K.M. Unice, P.K. Scott, L.C. Haws, D.J. Paustenbach. 2007. Development of PCDD/F and dioxin-like PCB serum concentration reference values for the general U.S. population using the 2006 WHO TEFs and the 2001-2002 NHANES data.Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Finnerty K, Choi JE, Lau A, Davis-Gorman G, Diven C, Seaver N, Linak WP, Witten M, McDonagh PF. 2007. Instillation of coarse ash particulate matter and lipopolysaccharide produces a systemic inflammatory response in mice. J Toxicol Environ Health Part A 70:1957–1966, doi: 10.1080/15287390701549229.

View Abstract

Liebelt EL, Balk SJ, Faber W, Fisher JW, Hughes CL, Lanzkron SM, Lewis KM, Marchetti F, Mehendale HM, Rogers JM, Shad AT, Skalko RG, Stanek EJ. 2007. NTP-CEHR expert panel report on the reproductive and developmental toxicity of hydroxyurea. Birth Defects Res Part B, Dev Reprod Toxicol 80:259–366.

View Abstract

Urban JD, Clarke WP, von Zastrow M, Kobilka B, Nichols DE, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, Miller KJ, Spedding M, and Mailman RB. 2007. Functional selectivity and classical concepts of quantitative pharmacology. J. Pharmacol Exp Therap. 320 (1): 1-13.

Harris, M., L.L.F. Scott, L.M. Nguyen, and L.C. Haws. 2007. Trends in elevated blood lead levels of U.S. children and associated demographic characteristics. Ann Epidemiol 17:748.

Urban JD, Vargas G, von Zastrow M, and Mailman RB. 2007. Aripiprazole has functionally selective actions at D2 receptor-mediated signaling pathways. Neuropsychopharmacology. 32 (1): 67-77.

Harris, M.J.A.Tachovsky, E.S. Williams, L.L.F Scott, L. Nguyen, L.C. Haws. 2007. Risks Posed by Air Pollutants in the Houston Metropolitan Area. Society for Risk Analysis Annual Meeting. December 9-12, 2007. San Antonio, TX.

Lea IA, Jackson MA, Li X, Bailey S, Peddada SD, Dunnick JK. 2007. Genetic pathways and mutation profiles of human cancers: Site- and exposure-specific patterns. Carcinogenesis 28:1851–1858.

View Abstract

Harris, M.L.C. Haws, A. Tachosvky, E.S. Williams, L.M. Nguyen, L.F. Scott. Interactive Processes in Toxicity Assessments. Air Toxics Research: Implications of Research on Policies to Protect Public Health. June 12-13, 2007. Houston, TX.

Haws, L.C., L.L.F. Scott, D.F. StaskalM.A. Harris, and B.L. Finley. 2007. Dioxin-like compounds in workers at a primary magnesium production facility. Dioxin 2007, September 2-7, 2007. Tokyo, Japan.

Haws, L.C., L.L.F. Scott, D.F. StaskalM. Harris, and B. Finley. 2007. Evaluation of Biomonitoring Data for Dioxin-like Compounds in Workers at a Primary Magnesium Production Facility. Society for Risk Analysis Annual Meeting. December 9-12, 2007. San Antonio, TX.

Haws LC, Walker NJ, DeVito MJ, Birnbaum LS, Unice KM, Scott PK, Harris MA, Farland WH, Finley BL, Staskal DF. 2007. Development of weighted distributions of REPs for dioxin-like compounds (DLCs). Society of Toxicology Annual Meeting. March 25-29, Charlotte, NC.

Nguyen, L.M., L.L.F. Scott, M. Harris, and L.C. Haws. Factors Contributing to Blood Lead Levels in U.S. Children Based on NHANES Data. 2007 Ann Epidemiol. 17:734-735.

Perry, C.S. Vibrios in surface waters and a hypothetical scenario using EPA’s Environmental Consequence Assessment Tool (ECAT). Society for Risk Analysis annual meeting, December 9-12, 2007. San Antonio, TX.

Scott, L.L.F., M. Harris, K.M. Unice, P. Scott, L.M. Nguyen, L.C. Haws, and D. Paustenbach. 2007. Effects of excluding serum PCDD/F and dioxin-like PCB data of individuals with incomplete congener profiles on estimates of total TEQ. Ann Epidemiol. 17:732.

Scott, P., L.C. Haws, L. Scott, and M. Harris. 2007. Evaluation of Background 2,3,7,8-PCDD/F Congener Profiles in Human Serum Collected During NHANES 2001-2002 Using Principal Components Analysis. Dioxin 2007, September 2-7, 2007. Tokyo, Japan.

Scott, P., L.C. Haws, L. Scott, and M. Harris. 2007. Evaluation of Background Dioxin-like PCB Congener Profiles in Human Serum Collected During NHANES 2001-2002 Using Principal Components Analysis. Dioxin 2007, September 2-7, 2007. Tokyo, Japan.

Smith, J.D., Perry C., Garcia, S., Jenkins, A., Dwyer, M., Garrahan, K. Emergency Consequence Assessment Tool (ECAT) for USEPA NHSRC. Society for Risk Analysis annual meeting, December 9-12, 2007. San Antonio, TX.

Staskal, D.F., E.P. Donovan, L.C. Haws, J.D. Roberts, K.M. Unice, B.L. Finley, and M.A. Harris. A Quantitative Microbial Risk Assessment for Exposure to Pathogens in Waters and Sediments of the Lower Passaic River. Society for Risk Analysis annual meeting, December 9-12, 2007. San Antonio, TX.

Staskal, D.F., L.L.F. Scott, E.S. Williams, W.J. Luksemburg, L.C. Haws, L.S. Birnbaum, L.M. Nguyen, D.J. Paustenbach, and M.A. Harris. Daily intake estimates of PBDEs associated with consumption of catfish in the U.S. Presented at the Fourth International Workshop on Brominated Flame Retardants. April 24-27, 2007. Amsterdam, the Netherlands.

Staskal, D.F., E. Donovan, J. Roberts, K. Unice, B. Finley, and M. Harris. 2007. Human Health Risk Associated with Exposure to Pathogen-Contaminated Sediments. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Tachovsky, J.A., L.C. Haws, L.F Scott, E.S. Williams, and M. Harris. Benzene in soft drinks and other beverages: Do measured levels pose a human health risk? Society for Risk Analysis’ Annual Meeting. December 9-12, 2007. San Antonio, TX.

Urban, J.D., K. Thornley, R.W. Wightman, and R.B. Mailman. 2007. Pharmacological characterization of the N27-D2L cell line: assessment as a viable cell model for investigating D2L receptor dopaminergic-coupled functions. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Williams, E.S., L.L. Ferriby, L.C. Haws, D.J. Paustenbach, and M.A. Harris. 2007. Assessment of potential human health risks posed by benzene in a commercial beverage. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

2006

Boice JD Jr, Marano DE, Cohen SS, Mumma MT, Blot WJ, Brill AB, Fryzek JP, Henderson BE, McLaughlin JK. 2006. Mortality among Rocketdyne workers who tested rocket engines, 1948-1999. J Occup Environ Med 48(10):1070-1092.

View Abstract

Barone S Jr., Brown RC, Euling S, Cohen Hubal E, Kimmel CA, Makris S, Moya J, Selevan SG, Sonawane B, Thomas T, and Thompson CM. 2006. Visión General De La Evaluación Del Rieso En Salud Infantil Empleando Un Enfoque Por Etapas De Desarrollo. Acta Toxicol Argent 14(Suppl):7–10.

Ferriby, L.L., E.S. Williams, W.J. Lukesemburg, D.J. Paustenbach, L.C. Haws, L.S. Birnbaum, and M. Harris. 2006. Comparing polychlorinated biphenyls in farm-raised and wild-caught catfish from southern Mississippi. Organohalogen Compounds. 68: 2527-2530.  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Becker DS, Long ER, Proctor DM, Ginn TC. 2006. Toxicity and bioavailability of chromium in sediments associated with chromite ore processing residue.  Environ Toxicol Chem. 25(10):2576–2583.

Ferriby, L.L., E.S. Williams, W.J. Lukesemburg, D.J. Paustenbach, L.C. Haws, L.S. Birnbaum, and M. Harris. 2006. Comparing PCDDs, PCDFs, and Dioxin-Like PCBs in Farm-Raised and Wild-Caught Catfish from Southern Mississippi.  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Boice JD, Cohen SS, Mumma MT, Dupree Ellis E, Eckerman KF, Leggett RW, Boecker BB, Brill AB, Henderson BE. 2006. Mortality among radiation workers at Rocketdyne (Atomics International), 1948-1999. Radiat Res 166(1 Pt 1):98-115. Erratum in: Radiat Res. 2006 Sep;166(3):566.

View Abstract

Haws LC, Su S, Harris MA, DeVito M, Walker N, Farland W, Finley B, and Birnbaum L. 2006. Development of a refined database of mammalian relative potency estimates for dioxin-like compounds. Toxicol Sci. 89(1):4-30.

Ferriby, L.L., K. Franke, K.M. Unice, P. Scott, L.C. HawsM. Harris, and D.J. Paustenbach. 2006. Serum reference levels of PCDD/Fs and dioxin-like PCBs stratified by race/ethnicity, gender and age for the general U.S. population. American Public Health Association Annual Meeting and Exposition. November 4-8, 2006. Boston, MA.

Boice JD Jr, Leggett RW, Ellis ED, Wallace PW, Mumma M, Cohen SS, Brill AB, Chadda B, Boecker BB, Yoder RC, Eckerman KF. 2006. A comprehensive dose reconstruction methodology for former Rocketdyne/Atomics International radiation workers. Health Phys 90(5):409-430.

View Abstract

Robison SH, Greggs W, Hochwalt AE, Kohrman K, Kosemund K, McMillan DA, Naciff JN. Diethyl phthalate — Biomonitoring based risk assessment. Toxicologist 90:257 (Abstract 1260), 2006.

Paustenbach DJ, Fehling K, Scott P, Harris M, and Kerger B. 2006. Identifying soil clean-up criteria for dioxin in urban residential soils: How have 20 years of research and risk assessment experience affected the analysis? J Toxicol Environ Health, Part B. 9:87-145.

Finster M., MacDonell, M., Bhattacharyya, M., Haroun L., Peterson J., and Perry, C. Environmental fate and cumulative risk context for cleanup programs. Society for Risk Analysis’ Annual Meeting. December 3-6, 2006. Baltimore, MD.

Mahony C, Felter SP, McMillan DA. 2006. An exposure-based risk assessment approach to confirm the safety of hydrogen peroxide for use in home tooth bleaching. Regul Toxicol Pharmacol 44:75–82.

View Abstract

Staskal DF, Diliberto JJ and Birnbaum LS. 2006. Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. Toxicol Sci. 89:380-5.

Gough, M., D. Paustenbach, B. Kerger, H. Leung, P. Scott, and M. Harris. 2006. Dioxin and diabetes does the current weight of evidence demonstrate a relationship. Society of Toxicology. March 5-9, 2006. San Diego, CA.

Paustenbach DJ, Gaffney SA, Scott PK, Brown JL, Panko JM. High background levels of urinary benzene metabolites found in volunteer study. Society of Toxicology Conference 2006.

Paustenbach DJ, Panko JM, Scott PK, Unice KM. Retrospective modeling of potential residential exposure to perfluorooctanoic acid (PFOA) releases from a manufacturing facility. Society of Toxicology Conference 2006.

Panko JM, Shay EC. Potential for airborne dispersion of bromadiolone and exposure in an office setting. International Society for Exposure Assessment Conference 2006.

Panko JM, Unice KM, Shay EC, Price P. Assessment of children’s exposures to xylenes. International Society for Exposure Assessment Conference 2006.

Panko JM, Unice KM, Shay EC, Javier AF. 2006. Assessment of children’s exposures to benzene. Society for Risk Analysis, December 2006.

Staskal DF, Diliberto JJ, and Birnbam LS. 2006. Disposition of BDE 47 in developing mice. Toxicol Sci. 90:309-16.

Harris, M., L. Ferriby, J. Knutsen, P. Nony, K. Unice, and D. Paustenbach. 2006. Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey in the United States. Society of Toxicology. March 5-9, 2006. San Diego, CA.

Law CL, Gordon KA, Toki BE, Yamane AK, Hering MA, Cerveny CG, Petroziello JM, Ryan MC, Smith L, Simon R, Sauter G, Oflazoglu E, Doronina SO, Meyer DL, Francisco JA, Carter P, Senter PD, Copland JA, Wood CG, Wahl, AF. 2006. Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates. Cancer Res 66:2328–2337.

View Abstract

McDonagh CF, Turcott E, Westendorf L, Webster JB, Alley SC, Kim K, Andreyka J, Stone I, Hamblett KJ, Francisco JA, Carter P. 2006. Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment. Protein Eng Design Select 19:299–307.

View Abstract

Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM, Lindstrom AB, Strynar MJ. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicol Sci 90:510–518.

View Abstract

Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM, Lindstrom AB, Strynar MJ. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicol Sci 90:510–518.

View Abstract

Rogers JM. 2006. Toxicological highlight. Casting a broad network: Fishing for mechanisms of retinoid teratogenicity. Toxicol Sci 94:1–2.

View Abstract

Staskal DF, Hakk H, Bauer D, Diliberto JJ, and Birnbam LS. 2006. Toxicokinetics of Polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Toxicol Sci. 94:28-37.

Haws, L. The use of toxic equivalency factors to assess potential human health risks posed by dioxin-like compounds: Keeping up with the science. Presented at Michigan State University, Toxicology Program Seminar Series. September 26, 2006.

 

Loretz L, Barraj L, Burdick J, Davis de A, Dressler W, Gilberti E, Jarrett G, Mann S, Laurie Pan YH, Re T, Renskers K, Scrafford C, Vater S. 2006. Exposure data for personal care products: Hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food Chem Toxicol 44(12):2008–2018.

View Abstract

Loretz L, Barraj L, Burdick J, Davis de A, Dressler W, Gilberti E, Jarrett G, Mann S, Laurie Pan YH, Re T, Renskers K, Scrafford C, Vater S. 2006. Exposure data for personal care products: Hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food Chem Toxicol 44(12):2008–2018.

Van den Berg M, Birnbaum L, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws LC, Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, Tuomisto J, Tysklind M, Walke Nr, and Peterson RE. 2006. The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds. Toxicol Sci 93(2):223-241.

View Abstract

Haws, L.C., P.K. Scott, K.M. Unice, M. Gough, M.A. HarrisD.F. Staskal, D.J. Paustenbach, and M. Pavuk. Are Dioxin Body Burdens Surrogates for Other Risk Factors in Associations Between Dioxin and Diabetes?  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Jackson MA, Lea I, Rashid A, Peddada SD, Dunnick JK. 2006. Genetic alterations in cancer knowledge system: Analysis of gene mutations in mouse and human liver and lung tumors. Toxicol Sci 90:400–418.

View Abstract

Haws, L.C., M.J. DeVito, L.S. Birnbaum, N.J. Walker, P.K. Scott, K.M. Unice, M.A. Harris, W.H. Farland, B.L. Finley, and D.F. Staskal. An Alternative Method for Establishing TEFs for Dioxin-like Compounds. Part 2. Development of An Approach To Quantitatively Weight the Underlying Potency Data. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Paustenbach, D.J., M.. Harris, L.L. Ferriby, E.S. Williams, L.C. Haws, K.M. Unice, and P.K. Scott. 2006. Development of PCDD/F TEQ serum reference values for the U.S. population for use in evaluating biomonitoring results. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Richardson, V.M., D.F. Staskal, J.J. Diliberto, and L.S.Birnbaum. 2006. Effects of BDE 47 on nuclear receptor regulated genes and implications for thyroid hormone disruption. 45th Annual Meeting of Society for Toxicology. March 5-9, 2006. San Diego, CA.

Staskal, D.F., L.L. Ferriby, E.S. Williams, W.J. Luksemburg, L.C. Haws, L.S. Birnbaum, D.J. Paustenbach, and M. Harris. 2006. Polybrominated diphenyl ethers in southern Mississippi catfish. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Staskal, D.F., J.J. Diliberto, and L.S. Birnbaum. 2006. Effect of age on the tissue distribution of BDE 47 in mice. 45th Annual Meeting of Society for Toxicology. March 5-9, 2006. San Diego, CA.

Urban, J.D., J. Jin, and R.B. Mailman. 2006. N27 dopaminergic cell line: A useful model for studying the mechanisms of action of functionally selective dopaminergic compounds. 45th Annual Meeting of Society for Toxicology. March 5-9, 2006. San Diego, CA.

Van den Berg, M., L. Birnbaum, M. Denison, M. De Vito, W. Farland, M. Feeley, H. Fiedler, H. Hakansson, A. Hanberg, L.C. Haws, M. Rose, S. Safe, D. Schrenk, C. Tohyama, A. Tritscher, J. Tuomisto, M. Tysklind, N. Walker, and R.E. Peterson. 2006. Human And Mammalian Toxic Equivalency Factors For Dioxins And Dioxin-like Compounds: The WHO 2005 Re-Evaluation.  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Paustenbach, D.J., L.L.F. Scott, L.M. Nguyen, K.M. Unice, P. Scott, L.C. Haws, and M. Harris. 2007. Referent Concentrations of PCDD/Fs and Dioxin-like PCBs in Sera of Persons in the U.S. Based on the New WHO 2006 TEFs and 2001-2002 NHANES Data. Ann Epidemiol. 17:734.

2005

Bauer, D., D.F. Staskal, J.J. Diliberto, and L.S. Birnbaum. 2005. Disposition of BDE 99 and BDE 153 in female mice. Society of Toxicology. March 6-10, 2005. New Orleans, LA.

Connor, K., M. Harris, M. Edwards, A. Chu, G. Clark, and B. Finley. 2005. Estimating the total TEQ in human blood from naturally-occurring vs. anthropogenic dioxins: A dietary study.  Dioxin 2005. August 21-26, 2005. Toronto, Canada.

Harris, M., and B. Finley. Estimating the total TEQ in human blood from naturally-occurring vs. anthropogenic dioxins: a dietary study. Society of Toxicology. March 6-10, 2005. New Orleans, LA.

Ulrich K, Stern M, Goddard ME, Williams J, Zhu J, Dewar A, Painter HA, Jeffery PK, Gill DR, Hyde SC, Geddes DM, Takata M, Alton Show EWFW. 2005. Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury. Lung Cell Molec Physiol 288(6).

View Abstract

Harris, M., B. Finley, P. Scott. Development of a relative estimate of potency distribution for 2,3,7,8-TCDF. Dioxin 2005. August 21-26, 2005. Toronto, Canada.

Haws, L. Evaluating Potential Health Risks Posed By PCDDs, PCDFs, and Dioxin-like PCBs: An Approach for Improving the Toxicity Equivalency Factor (TEF) Methodology. 30th Annual Winter Meeting of the Toxicology Forum. February 2, 2005. Washington, DC.

Scott PK, Unice KM, Panko JM. Statistical evaluation of metals concentrations as a method for identifying World Trade Center dust. International Society for Exposure Assessment 2005.