2020 (6 POSTS)

Thompson CM, Ring C, Pham L, Chappell GA, Haws LC. Assessment of the relevance of toxicological findings in the development of an oral reference dose for GenX. Poster for Society of Toxicology 59th Annual Meeting, Virtual, 2020.

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Thompson CM, Gentry R, Fitch S, Lu K, Clewell HJ. 2020. An updated mode of action and human relevance framework evaluation for formaldehyde-related nasal tumors. Crit Rev Toxicol 50(10):919–952; doi: 10.1080/10408444.2020.1854679.

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Gentry R, Thompson CM, Franzen A, Salley J, Albertini R, Lu K, Greene T. 2020. Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia. Crit Rev Toxicol 50(10):885–918, DOI: 10.1080/10408444.2020.1854678.

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2019 (13 POSTS)

Thompson C, Chappell G, Cullen J, Wolf JC, Haws L. Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic Meeting, Durham, NC, August 2019.

Chappell GA, Thompson CM, Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.

Thompson CM. The useful chemistry of perfluorinated compounds: Managing safety. The sticky subject of non-stick: Regulatory science challenges of per- and poly-fluorinated compounds (PFAS). Texas A&M University Interdisciplinary Faculty of Toxicology Training Program, 2019 Annual Regulatory Science Symposium, August 2019.

Andersen ME, Gentry PR, Swenberg JA, Mundt KA, White KW, Thompson C, Bus J, Sherman JH, Greim H, Bolt H, Marsh GM, Checkoway H, Coggon D, Clewell HJ. 2019. Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop. Regul Toxicol Pharmacol 106(Aug):210–223; doi: 10.1016/j.yrtph.2019.04.015.

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Clewell RA, Thompson CM, Clewell HJ. 2019. Dose-dependence of chemical carcinogenicity: Biological mechanisms for thresholds and implications for risk assessment. Chem Biol Interact 301(March):112–127; doi: 10.1016/j.cbi.2019.01.025.

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Chappell G, Rager J, Wolf J, Babic M, Leblanc, Ring C, Harris MA, Thompson CM. 2019. Comparison of gene expression responses in the small intestine of mice following exposure to three carcinogens using the S1500+ gene set informs a potential common adverse outcome pathway. Toxicol Pathol 47(7):851-864; doi: 10.1177/0192623319873.

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Thompson CM, Fitch SE, Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol 39:1267–1282.

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Klaren WD, Ring C, Harris MA, Thompson CM, Borghoff S, Sipes NS, Hsieh JH, Auerbach SS, Rager JE. 2019. Identifying attributes that influence in vitro-to-in vivo concordance by comparing Tox21 bioactivity versus DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci 167(1):157–171; doi: 10.1093/toxsci/kfy220. PMID: 30202884.

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Gentry R, Greene T, Granzen A, Thompson CM. Formaldehyde and leukemia: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

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Thompson CM, Gentry R. An updated mode-of-action analysis for formaldehyde-induced nasal tumors in rodents: A case study using the IPCS MOA and human relevance frameworks. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

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Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C. Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

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Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

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Rager JE, Suh M, Chappell G, Thompson CM, Proctor DM. 2019. Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis. Toxicol Lett 305(May 1):40-50; doi: 10.1016/j.toxlet.2019.01.011.

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2018 (7 POSTS)

Wikoff DS, Thompson C, Rager J, Chappell G, Fitch S, Doepker C. 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120:709-723; doi: 10.1016/j.fct.2018.08.031.

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Moffat I, Martinova N, Seidel C, Thompson CM. 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044.

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Thompson CM, Wolf JC, Suh M, Proctor DM, Haws LC, Harris MA. Toxicity and recovery in the duodenum of B6C3F1 mice following treatment with intestinal carcinogens; captan, folpet, and hexavalent chromium: Evidence for an adverse outcome pathway. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018.

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Thompson CM, Suh M, Proctor DM, Harris MA. Ten factors for considering the mode of action of Cr(VI)-induced intestinal tumors in rodents. Society of Toxicology Annual Meeting, San Antonio, TX, March 11-15, 2018.

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