2016 (10 POSTS)
Thompson CM , Suh M , Proctor DM , Rager JE, Haws LC , Harris MA. Assessment of the in vivo genotoxicity of CrVI in target organs identified in a two-year cancer bioassay. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: chromium , Cr(VI) MOA Study , Hexavalent Chromium
Brorby GP , Suh M , Thompson CM , Mittal L , Proctor DM . Inhalation cancer risk assessment of cobalt metal. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: Cancer , cobalt , Metals , risk assessment
Cullen JM, Ward JM, Thompson CM . 2016. Reevaluation and classification of duodenal lesions in B6C3F1 mice and F344 rats from 4 studies of hexavalent chromium in drinking water. Toxicol Pathol 44(2):279-89; doi: 10.1177/0192623315611501 .
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Topics: chromium , Cr(VI) MOA Study , Hexavalent Chromium
2015 (10 POSTS)
Proctor D , Suh M , Thompson C , Hixon, G. Inhalation cancer risk assessment of titanium dioxide. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: Cancer , risk assessment , titanium dioxide
Urban JD , Thompson CM , Plunkett LM, Perry CS , Haws LC . A state of the science copper reference dose for soil remediation. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: Copper , Metals , remediation
Harris MA, Thompson CM , Proctor DM , Suh M , Wolf JC, Seiter JM, Chappell MA, Haws LC. Analysis of duodenal crypt health following exposure to Cr(VI) in drinking water. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: Hexavalent Chromium
Thompson CM , Young RR, Suh M , Dinesdurage H, Elbekai R, Harris MA, Rohr AC, Proctor DM . Hexavalent chromium does not induce mutations in the oral mucosa of transgenic Big Blue® rats following drinking water exposures at a carcinogenic dose. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: Hexavalent Chromium
Thompson CM , Suh M , Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: dioxin , modeling , risk assessment , Toxicology
Borghoff SJ , Wikoff D , White MC, Thompson C , Haws LC . Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: flame retardants
Thompson CM , Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M , Proctor DM , Bichteler A, Haws LC , Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66.
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
Thompson CM , Young RR, Suh M , Dinesdurage HR, Elbekai RH, Harris MA, Rohr AC, Proctor DM . 2015. Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats. Environ Mol Mutagen 56(7):621-628; doi: 10.1002/em.21952 .
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
Young RR, Thompson CM , Dinesdurage HR, Elbekai RH, Suh M , Rohr AC, Proctor DM. 2015. A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats. Environ Mol Mutagen 56(7):629-636; doi: 10.1002/em.21951 .
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Topics: Toxicology
Thompson CM , Seiter J, Chappell MA, Tappero RV, Proctor DM , Suh M , Wolf JC, Haws LC , Vitale R, Mittal L , Kirman CR, Hays SM, Harris MA. 2015. Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water. Toxicol Sci 143(1):16-25.
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Topics: Cr(VI) MOA Study , Hexavalent Chromium
2014 (9 POSTS)
Haws LC, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Wikoff D . Development of non-cancer based toxicity factors and daily dose estimates for TBBPA. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: Cancer , flame retardants , Toxicology
Kirman CR, Proctor D, Suh M, Thompson CM , Harris MA, Haws LC , Hays SM. Variation analysis of PBPK model parameters for describing the delivery of Cr(VI) to the small intestines of humans. Presented at the Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: Hexavalent Chromium
Proctor DM , Suh M , Campleman SL, Thompson CM . 2014. Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures. Toxicol 325(Nov):160-179; doi: 10.1016/j.tox.2014.08.009 .
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Topics: Cancer , chromium , Cr(VI) MOA Study , Exposure Assessment , Hexavalent Chromium
Johnson GE, Soeteman-Hernandez, Gollapudi BB, Bodger OG, Dearfield KL, RH Heflich, Hixon JG, Lovell DP, MacGregor JT, Pottenger LH, Thompson CM , Abraham L , Thybaud V, Tanir JY, Zeiger E, van Benthem J, White PA. 2014. Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment. Environ Molec Mutagen 55(8):609-623; doi: 10.1002/em.21870/em.21870 .
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Topics: risk assessment , Toxicology
Hixon JG, Thompson C, Bichteler A, Abraham L. Smoothing regression splines as the basis for dose-response modeling. Presented at the Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: modeling , Toxicology
Thompson CM, Proctor DM, Suh M, Wolf JC, Haws LC, Seiter JM, Chappell MA, Harris MA. X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: chromium
Wikoff D, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Haws LC. Development of an oral cancer slope factor and lifetime average daily dose estimates for TBBPA. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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