2016 (10 POSTS)
Thompson CM , Rager JE, Suh M , Ring CL, Proctor DM , Haws LC , Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57(9):706-716; doi: 10.1002/em.22064 . PMID: 27859739.
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Topics: chromium , risk assessment , transcriptomics
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM . 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80(Oct):60-70; doi: 10.1016/j.yrtph.2016.05.031 . PMID: 27233922.
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Topics: Air Quality , mode of action , Systematic Review , titanium dioxide
Rager J, Thompson C , Auerbach S, Fry R. Integrating genomic and epigenomic data into risk assessment applications through dose response modeling: Case study with prenatal arsenic exposure. Environmental Mutagenesis and Genomics Society, Kansas City, KS, September 2016.
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Topics: arsenic
Suh M , Thompson CM , Brorby GP , Mittal L , Proctor DM . 2016. Inhalation cancer risk assessment of cobalt metal. Regul Toxicol Pharm 79(Aug):74-82; doi: 10.1016/j.yrtph.2016.05.009 . PMID: 27177823.
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Topics: Cancer , cobalt , Metals , risk assessment
Cullen JM, Ward JM, Thompson CM . Re-evaluation and classification of duodenal lesions in B6C3F1 mice and F344 rats from four studies of hexavalent chromium in drinking water. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: chromium , water
Thompson CM , Suh M , Proctor DM , Rager JE, Haws LC , Harris MA. Assessment of the in vivo genotoxicity of CrVI in target organs identified in a two-year cancer bioassay. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: chromium , genotoxicity
Brorby GP , Suh M , Thompson CM , Mittal L , Proctor DM . Inhalation cancer risk assessment of cobalt metal. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: Cancer , cobalt , Metals , risk assessment
Thompson CM . Non-mutagenic MOA for Cr(VI) involving intestinal cytotoxicity and regenerative hyperplasia. Platform presentation in the “The Cancer Risk Assessment for Ingested Hexavalent Chromium: Challenges and Controversies” Session. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.
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Topics: chromium
Cullen JM, Ward JM, Thompson CM . 2016. Reevaluation and classification of duodenal lesions in B6C3F1 mice and F344 rats from 4 studies of hexavalent chromium in drinking water. Toxicol Pathol 44(2):279-89; doi: 10.1177/0192623315611501 . PMID: 26538584.
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Topics: chromium , water
2015 (10 POSTS)
Thompson CM , Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M , Proctor DM , Bichteler A, Haws LC , Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66; doi: 10.1016/j.mrgentox.2015.05.004 . PMID: 26232259.
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Topics: chromium , microscopy
Thompson CM , Young RR, Suh M , Dinesdurage HR, Elbekai RH, Harris MA, Rohr AC, Proctor DM . 2015. Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats. Environ Mol Mutagen 56(7):621-628; doi: 10.1002/em.21952 . PMID: 26010270.
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Topics: chromium
Young RR, Thompson CM , Dinesdurage HR, Elbekai RH, Suh M , Rohr AC, Proctor DM. 2015. A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats. Environ Mol Mutagen 56(7):629-636; doi: 10.1002/em.21951 . PMID: 25969955.
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Topics: mode of action
Proctor D , Suh M , Thompson C , Hixon, G. Inhalation cancer risk assessment of titanium dioxide. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: Cancer , risk assessment , titanium dioxide
Urban JD , Thompson CM , Plunkett LM, Perry CS , Haws LC . A state of the science copper reference dose for soil remediation. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: Metals , remediation
Harris MA, Thompson CM , Proctor DM , Suh M , Wolf JC, Seiter JM, Chappell MA, Haws LC . Analysis of duodenal crypt health following exposure to Cr(VI) in drinking water. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: chromium , water
Thompson CM , Young RR, Suh M , Dinesdurage H, Elbekai R, Harris MA, Rohr AC, Proctor DM . Hexavalent chromium does not induce mutations in the oral mucosa of transgenic Big Blue® rats following drinking water exposures at a carcinogenic dose. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: carcinogens , chromium , water
Thompson CM , Suh M , Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: dioxin , modeling , risk assessment
Borghoff SJ , Wikoff D , White MC, Thompson C , Haws LC . Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: flame retardants
Thompson CM , Seiter J, Chappell MA, Tappero RV, Proctor DM , Suh M , Wolf JC, Haws LC , Vitale R, Mittal L , Kirman CR, Hays SM, Harris MA. 2015. Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water. Toxicol Sci 143(1):16-25; doi: 10.1093/toxsci/kfu206 . PMID: 25352572.
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Topics: chromium , water
2014 (9 POSTS)
Proctor DM , Suh M , Campleman SL, Thompson CM . 2014. Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures. Toxicology 325(Nov):160-179; doi: 10.1016/j.tox.2014.08.009 . PMID: 25174529.
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