Publication Topic

Waters MD, Jackson MA, Lea IA. 2010. Characterizing and predicting carcinogenicity and mode-of-action using conventional and toxicogenomics methods. Mutat Res 705(3):184–200; doi: 10.1016/j.mrrev.2010.04.005.

Proctor DM, Gatto NM, Hong SJ, Allamneni KP. 2007. Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment. Toxicol Sci 98(2):313–326; doi: 10.1093/toxsci/kfm075.

Borowsky AD, Dingley KH, Ubick E, Turteltaub KW, Cardiff RD, Devere-White R. 2006. Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model. Neoplasia 8(9):708–715; doi: 10.1593/neo.06373. PMID: 16984728.

Malfatti MA, Dingley KH, Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573. PMID: 17079477.

Chepanoske CL, Brown K, Turteltaub KW, Dingley KH. 2004. Characterization of a peptide adduct formed by N-acetoxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a reactive intermediate of the food carcinogen PhIP. Food Chem Toxicol 42(8):1367–1372; doi: 10.1016/j.fct.2003.11.012. PMID: 15207388.

Mally A, Zepnik H, Wanek P, Eder E, Dingley K, Ihmels H., et al. 2004. Ochratoxin A: Lack of formation of covalent DNA adducts. Chem Res Toxicol 17(2):234–242; doi: 10.1021/tx034188m. PMID: 14967011.

Kim DJ, Akiyama TE, Harman FS, Burns AM, Shan W, Ward JM, Kennett MJ, Gonzalez FJ, Peters JM. 2004. Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis. J Biol Chem 279(22):23719-23727; doi: 10.1074/jbc.M312063200. PMID: 15033975.

Turesky RJ, Richoz J, Constable A, Curtis KD, Dingley KH, Turteltaub KW. 2003. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats. Chem-Biol Interact 145(3):251–265; doi: 10.1016/S0009-2797(03)00022-X. PMID: 12732453.

Roberts SM, Jordan KE, Warren DA, Britt JK, James RC. 2002. Evaluation of the carcinogenicity of 1,1-dichloroethylene (vinylidene chloride). Regul Toxicol Pharmacol 35(1):44-55; doi: 10.1006/rtph.2001.1518.

Haws LC, Jackson BA, Turnbull D, Dressler WE. 1994. Two approaches for assessing human cancer risk from disperse blue 1. Regul Toxicol Pharmacol. 19(1):80-96; doi: 10.1006/rtph.1994.1007.

Monticello TM, Morgan KT. 1994. Cell proliferation and formaldehyde-induced respiratory carcinogenesis. Risk Anal 14(3):313-319; doi: 10.1111/j.1539-6924.1994.tb00246.x.

Jackson BA. Haws LC, Wixtrom RJ, Starr TB. Secondary mechanisms in carcinogenesis: Breaking out of the no-threshold paradigm. American College of Toxicology Annual Meeting, Savannah, GA, 1991.

Monticello TM, Renne R, Morgan KT. 1991. Chemically induced cell proliferation in upper respiratory tract carcinogenesis. Prog Clin Biol Res 369:323-225.

Goldsworthy TL, Monticello TM, Morgan KT, Bermudez E, Wilson D, Butterworth BE. 1991. Examination of potential mechanisms of carcinogenicity of 1,4-dioxane in rat nasal epithelial cells and hepatocytes. Arch Toxicol 65(1):1-9; doi: 10.1007/BF01973495.

Morgan KT, Monticello TM. 1989. Airflow, mucociliary clearance, and lesion distribution in the nasal passages of experimental animals. In: Feron VJ, Bosland MC (eds), Nasal Carcinogenesis in Rodents: Relevance to Human Risk. Wageningen, Netherlands: Pudec Publications, pp. 36-41.