Publication Topic

Hixon JG, Thompson C, Bichteler A, Abraham L. Smoothing regression splines as the basis for dose-response modeling. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.

Wheeler MW, Bailer AJ. 2013. An empirical comparison of low-dose extrapolation from points of departure (PoD) compared to extrapolations based upon methods that account for model uncertainty. Regul Toxicol Pharmacol 67(1):75-82; doi: 10.1016/j.yrtph.2013.06.006. PMCID: PMC4724873

Wheeler MW, Bailer AJ. 2012. Monotonic Bayesian semiparametric benchmark dose analysis. Risk Anal 32(7):1207-18; doi: 10.1111/j.1539-6924.2011.01786.x. PMID: 22385024.

Hixon JG, Proctor D. Use of constrained logistic regression models for the dose-response analysis of beryllium sensitization and chronic beryllium disease with mean exposure. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Maier A, Kohrman-Vincent M, Hertzberg R, Allen B, Haber LT, Dourson M. 2012. Critical review of dose-response options for F344 rat mammary tumors for acrylamide – Additional insights based on mode of action. Food Chem Toxicol 50(5):1763–1776; doi: 10.1016/j.fct.2012.02.002. PMID: 22366097.

Dourson M, Kohrman-Vincent M, Allen B, Cain W. 2010. Dose response assessment from effects of acute exposure to methyl isothiocyanate (MITC). Regul Toxicol Pharmacol 58(2):181–188; doi: 10.1016/j.yrtph.2010.04.006. PMID: 20406661.

Wheeler MW, Bailer AJ. 2008. Model averaging software for dichotomous dose response risk estimation. J Stat Software 26(5):1-15; doi: 10.18637jss.v026.i05.

Wheeler MW, Fadel W, Robertson J, John Bailer A. 2007. Confidence interval construction for relative toxicity endpoints such as LD₅₀ or LD₉₀ ratios. J Econ Entomol 100(6):1945-9; doi: 10.1093/jee/100.6.1945. PMID: 18232415.

Wheeler MW, Bailer AJ. 2007. Properties of model‐averaged BMDLs: A study of model averaging in dichotomous response risk estimation. Risk Anal 7(3):659-70; doi: 10.1111/j.1539-6924.2007.0090.x. PMID: 17640214.

Marino DJ, Clewell HJ, Gentry PR, Covington TR, Hack CE, David RM, Morgott DA. 2006. Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose-response modeling in mice. Regul Toxicol Pharmacol 45(1):44–54; doi: 10.1016/j.yrtph.2005.12.007. PMID: 16442684.

Slikker W Jr., Andersen ME, Bogdanffy MS, Bus JS, Cohen SD, Conolly RB, David RM,…, Rogers JM, et al. 2004. Dose-dependent transitions in mechanisms of toxicity. Toxicol Appl Pharmacol 201(3):203–225; doi:10.1016/j.taap.2004.06.019. PMID: 15582645.

Rogers JM, Setzer RW, Branch S, Chernoff N. 2004. Chemically-induced supernumerary ribs in CD-1 mice: Size distribution and dose-response. Birth Defects Res B 71(1):17–25; doi: 10.1002/bdrb.10055. PMID: 14991907.

Crump C, Crump K, Hack E, Luippold R, Mundt K, Liebig EW, Panko JM, Paustenbach DJ, Proctor DM. 2003. Dose-response and risk assessment of airborne hexavalent chromium and lung cancer mortality. Risk Anal 23(6):1147–1163; doi: 10.1111/j.0272-4332.2003.00388.x. PMID: 14641890.

Lau C, Mole ML, Copeland FM, Rogers JM, Kavlock RJ, Shuey DL, Cameron AM, Ellis DH, et al. 2001. Toward a biologically-based dose-response model for the developmental toxicity of 5-fluorouracil in the rat: Acquisition of experimental data. Toxicol Sci 59(1):37–48; doi: 10.1093/toxsci/59.1.37. PMID: 11134542.

Setzer RW, Lau C, Mole ML, Copeland FM, Rogers JM, Kavlock RJ. 2001. Toward a biologically-based dose-response model for the developmental toxicity of 5-fluorouracil in the rat: A mathematical construct. Toxicol Sci 59(1):49–58; doi: 10.1093/toxsci/59.1.49. PMID: 11134543.

Lau C, Anderson ME, Crawford-Brown DJ, Kavlock RJ, Kimmel CA, Knudsen TB, Muneoka K, Rogers JM, Setzer RW, Smith G, Tyl R. 2000. Evaluation of biologically based dose-response modeling for developmental toxicity: A workshop report. Regul Toxicol Pharmacol 31(2 Pt 1):190–199; 10.1006/rtph.1999.1360. PMID: 10854125.