2019 (6 POSTS)
Scott PK, Abramson MM, Bare JL , Barlow CA. 2019. Air dispersion modeling for historical community exposure reconstruction: An evaluation of the approach and its uncertainties. EM-Mag Environ Mgrs January .
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Publication: Manuscripts
Sedykh A, Choksi N , Allen D, Kleinstreuer N, Casey W, Shah R. Mixture-based modeling of chemical ocular toxicity based on the US EPA hazard categories. Poster presented at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019
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Publication: Abstracts and Presentations
Swartz C, Howard AS, Choksi N , Rauer A, Allen DG, Recio L, Karmaus AL. An integrated approach for animal-free genotoxicity testing: In vitro and in silico evaluation and mode-of-action classification. Poster presented at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.
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Publication: Abstracts and Presentations
2018 (2 POSTS)
Casey WM, Chang X, Allen DG, Ceger PC, Choksi NY , Hsieh JH, et al. 2018. Evaluation and optimization of pharmacokinetic models for in vitro to in vivo extrapolation of estrogenic activity for environmental chemicals. Environ Health Perspect 126(9):97001; doi: 10.1289/EHP1655 .
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Publication: Manuscripts
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415; doi: 10.1080/10408444.2018.1430121 .
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Publication: Manuscripts
2017 (1 POST)
Kirman CR, Suh M, Proctor DM , Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325(15 June):9-17; doi: 10.1016/j.taap.2017.03.023 .
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Publication: Manuscripts
2016 (2 POSTS)
Cyrs WD, Dussex D, Glynn M, Finley BL . Benchmark dose modeling for respiratory irritation from 2,3-pentanedione exposure. Podium presentation at American Industrial Hygiene Conference & Exposition (AIHce), 2016.
Publication: Abstracts and Presentations
Glynn ME, Adams RE, Beckett EM, Scott PK, Pierce JS, Finley BL . Human equivalent concentrations for diacetyl based on minimal bronchiolar respiratory effects observed in animals: A refined analysis using current toxicology data and dosimetry models. Abstract #1300. Poster presentation at Society of Toxicology 55th Annual Meeting, New Orleans, LA, 2016.
Publication: Abstracts and Presentations
2015 (3 POSTS)
Thompson CM , Suh M , Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Publication: Abstracts and Presentations
Cowan DM, Maskrey JR, Fung E, Woods T, Stabryla L, Scott PK, Finley BL . Evaluation of empirically-based PBPK modeling approaches for modeling ante- and post mortem ethanol concentrations in biological matrices. Poster presentation Society of Toxicology 54th Annual Meeting, San Diego, CA, 2015.
Publication: Abstracts and Presentations
Knudsen TB, Keller DA , Sander M, Carney EW, Doerrer NG, Eaton DL, Fitzpatrick SC, Hastings KL, Mendrick DL, Tice RR, Watkins PB, Whelan M. 2015. FutureTox II: In vitro data and in silico models for predictive toxicology. Toxicol Sci 143(2):256–267; doi: 10.1093/toxsci/kfu234 .
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Publication: Manuscripts
2014 (2 POSTS)
Hixon JG, Thompson C, Bichteler A, Abraham L. Smoothing regression splines as the basis for dose-response modeling. Presented at the Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Publication: Abstracts and Presentations
Monnot AD, Christian WV, Paustenbach DJ, Finley BL . 2014. Correlation of blood Cr(III) and adverse health effects: Application of PBPK modeling to determine non-toxic blood concentrations. Crit Rev Toxicol 44(7):618–637; doi:10.3109/10408444.2014.926472 . PMID: 25068491.
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Publication: Manuscripts
2013 (1 POST)
Thompson CM , Gaylor DW, Tachovsky JA, Perry C, Carakostas MC, Haws LC . 2013. Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. J Appl Toxicol 33(12):1395-1406; doi: 10.1002/jat.2799 .
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Publication: Manuscripts
2012 (4 POSTS)
Unice KM, Monnot AD, Gaffney SH, Tvermoes BE, Thuett KA, Paustenbach DJ, Finley BL . 2012. Inorganic cobalt supplementation: Prediction of cobalt levels in whole blood and urine using a biokinetic model. Food Chem Toxicol 50(7):2456–2461; doi: 10.106/j.fct.2012.04.009 . PMID: 22538081.
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Publication: Manuscripts
Finley BL , Monnot AD, Gaffney SH, Paustenbach DJ. 2012. Dose-response relationships for blood cobalt concentrations and health effects: A review of the literature and application of a biokinetic model. J Toxicol Environ Health B, 15(8):493–523; doi: 10.1080/10937404.2012.744287 .
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Publication: Manuscripts
Knutsen JS, Kerger BD, Finley BL , Paustenbach DJ. 2012. A calibrated human PBPK model for benzene inhalation with urinary bladder and bone marrow compartments. Risk Anal 33 (7):1237–1251; doi: 10.1111/j.1539-6924.2012.01927.x . PMID: 23278103.
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Publication: Manuscripts
Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D . 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Publication: Abstracts and Presentations
2011 (2 POSTS)
Thompson C , Perry C , Gaylor D, Tachovsky A, Burkhalter B, Haws L . Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. Presented at Society of Toxicology 50th Annual Meeting, Washington DC, March 2011.
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Publication: Abstracts and Presentations
Wikoff DS, Thompson C, Walker N, DeVito M, Harris M, Birnbaum L, Haws L. Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF. Presented at Dioxin 2011, Brussels, Belgium, August 2011.