Publication Topic
modeling (76 POSTS)
2016 (2 POSTS)
Cyrs WD, Dussex D, Glynn M, Finley BL. Benchmark dose modeling for respiratory irritation from 2,3-pentanedione exposure. Podium presentation at American Industrial Hygiene Conference & Exposition (AIHce), 2016.
Glynn ME, Adams RE, Beckett EM, Scott PK, Pierce JS, Finley BL. Human equivalent concentrations for diacetyl based on minimal bronchiolar respiratory effects observed in animals: A refined analysis using current toxicology data and dosimetry models. Abstract #1300. Poster presentation at Society of Toxicology 55th Annual Meeting, New Orleans, LA, 2016.
2015 (4 POSTS)
Wheeler MW, Park R, Bailer A, Whittaker C. 2015. Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits. J Occup Environ Hyg 12(sup1):S7-S17; doi: 10.1080/15459624.2015.1076934. PMCID: PMC4685605.
View AbstractThompson CM, Suh M, Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
View AbstractCowan DM, Maskrey JR, Fung E, Woods T, Stabryla L, Scott PK, Finley BL. Evaluation of empirically-based PBPK modeling approaches for modeling ante- and post mortem ethanol concentrations in biological matrices. Poster presentation Society of Toxicology 54th Annual Meeting, San Diego, CA, 2015.
Knudsen TB, Keller DA, Sander M, Carney EW, Doerrer NG, Eaton DL, Fitzpatrick SC, Hastings KL, Mendrick DL, Tice RR, Watkins PB, Whelan M. 2015. FutureTox II: In vitro data and in silico models for predictive toxicology. Toxicol Sci 143(2):256–267; doi: 10.1093/toxsci/kfu234.
View Abstract2014 (2 POSTS)
Hixon JG, Thompson C, Bichteler A, Abraham L. Smoothing regression splines as the basis for dose-response modeling. Presented at the Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
View AbstractMonnot AD, Christian WV, Paustenbach DJ, Finley BL. 2014. Correlation of blood Cr(III) and adverse health effects: Application of PBPK modeling to determine non-toxic blood concentrations. Crit Rev Toxicol 44(7):618–637; doi:10.3109/10408444.2014.926472. PMID: 25068491.
View Abstract2013 (2 POSTS)
Wheeler MW, Bailer AJ. 2013. An empirical comparison of low-dose extrapolation from points of departure (PoD) compared to extrapolations based upon methods that account for model uncertainty. Regul Toxicol Pharmacol 67(1):75-82; doi: 10.1016/j.yrtph.2013.06.006. PMCID: PMC4724873
View AbstractThompson CM, Gaylor DW, Tachovsky JA, Perry C, Carakostas MC, Haws LC. 2013. Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. J Appl Toxicol 33(12):1395-1406; doi: 10.1002/jat.2799.
View Abstract2012 (4 POSTS)
Unice KM, Monnot AD, Gaffney SH, Tvermoes BE, Thuett KA, Paustenbach DJ, Finley BL. 2012. Inorganic cobalt supplementation: Prediction of cobalt levels in whole blood and urine using a biokinetic model. Food Chem Toxicol 50(7):2456–2461; doi: 10.106/j.fct.2012.04.009. PMID: 22538081.
View AbstractFinley BL, Monnot AD, Gaffney SH, Paustenbach DJ. 2012. Dose-response relationships for blood cobalt concentrations and health effects: A review of the literature and application of a biokinetic model. J Toxicol Environ Health B, 15(8):493–523; doi: 10.1080/10937404.2012.744287.
View AbstractKnutsen JS, Kerger BD, Finley BL, Paustenbach DJ. 2012. A calibrated human PBPK model for benzene inhalation with urinary bladder and bone marrow compartments. Risk Anal 33 (7):1237–1251; doi: 10.1111/j.1539-6924.2012.01927.x. PMID: 23278103.
View AbstractKirman CR, Hays SM, Aylward LL, Suh M, Proctor D. 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View Abstract2011 (2 POSTS)
Thompson C, Perry C, Gaylor D, Tachovsky A, Burkhalter B, Haws L. Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. Presented at Society of Toxicology 50th Annual Meeting, Washington DC, March 2011.
View AbstractWikoff DS, Thompson C, Walker N, DeVito M, Harris M, Birnbaum L, Haws L. Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF. Presented at Dioxin 2011, Brussels, Belgium, August 2011.
2010 (1 POST)
Johns DO, Owens EO, Thompson CM, Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.
View Abstract2009 (2 POSTS)
Thompson CM, Johns DO, Sonawane S, Barton HA, Hattis D, Tardif R, Krishnan K. 2009. Database for physiologically based pharmacokinetic (PBPK) modeling: Physiological parameters for healthy and health-impaired elderly. J Toxicol Environ Health B 12(1):1–24; doi: 10.1080/10937400802545060.
View AbstractWheeler MW, Bailer AJ. 2009. Comparing model averaging with other model selection strategies for benchmark dose estimation. Environ Ecol Stat 16:37-51; doi: 10.1007/s10651-007-0071-7.
View Abstract2008 (5 POSTS)
DeWoskin RS, Thompson CM. 2008. Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants. Regul Toxicol Pharmacol 51(June):66–86; doi: 10.1016/j.yrtph.2008.02.005.
View Abstract