Publication Topic

Kirman CR, Suh M, Proctor DM, Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325(15 June):9-17; doi: 10.1016/j.taap.2017.03.023. PMID: 28389273.

Judson RS, Martin M, Patlewicz G, Wood CE. 2017. Retrospective mining of toxicology data to discover multispecies and chemical class effects: Anemia as a case study. Regul Toxicol Pharmacol 86(June):74-92; doi: 10.1016/j.yrtph.2017.02.015. PMID: 28242142.

Borghoff SJ, Ring C, Banton M, Leavens TL. 2017. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol 37(5):621-640; doi: 10.1002/jat.3412. PMID: 27885692.

Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, et al. 2017. Multivariate models for prediction of human skin sensitization hazard. J Appl Toxicol 37:347–360; doi: 10.1002/jat.3366.

Borghoff SJ, Ring C, Banton MI, Leavens TL. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to 2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Kirman CR, Proctor D, Suh M, Haws L, Harris M, Thompson C, Hays S. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Covington TR, Pangburn HA, Mayes RS, Ott DK, Gearhart JM. Estimated inter-individual variations in high-performance aircraft pilot exposures using physiologically-based pharmacokinetic (PBPK) modeling and Monte Carlo analysis. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Cowan DM, Maskrey JR, Fung ES, Woods TA, Stabryla LM, Scott PK, Finley BL. 2016. Best-practices approach to determination of blood alcohol concentration (BAC) at specific time points: Combination of ante-mortem alcohol pharmacokinetic modeling and post-mortem alcohol generation and transport considerations. Regul Toxicol Pharmacol 78(July):24–36; doi: 10.1016/j.yrtph.2016.03.020.

Cyrs WD, Dussex D, Glynn M, Finley BL. Benchmark dose modeling for respiratory irritation from 2,3-pentanedione exposure. Podium presentation at American Industrial Hygiene Conference & Exposition (AIHce), 2016.

Covington TR, Lumley LA, Ruark CD, Clarkson ED, Whalley CE, Gearhart JM. 2016. Modeling organophosphorus chemical warfare nerve agents: A physiologically based pharmacokinetic-pharmacodynamic (PBPK-PD) model of VX. In: Worek F, Jenner J, Thiermann H (eds), Chemical Warfare Toxicology: Volume 1: Fundamental Aspects, pp. 213–263. Royal Society of Chemistry.

Barber C, Cayley A, Hanser T, Harding A, Heghes C, Vessey JD, Werner S,…, Greene N. 2016. Evaluation of a statistics-based Ames mutagenicity QSAR model and interpretation of the results obtained. Regul Toxicol Pharmacol 76(Apr):7-20; doi: 10.1016/j.yrtph.2015.12.006. PMID: 26708083.

Glynn ME, Adams RE, Beckett EM, Scott PK, Pierce JS, Finley BL. Human equivalent concentrations for diacetyl based on minimal bronchiolar respiratory effects observed in animals: A refined analysis using current toxicology data and dosimetry models. Abstract #1300. Poster presentation at Society of Toxicology 55^th Annual Meeting, New Orleans, LA, 2016.

Hack CE, Gearhart JM, Covington TR, Starr CR, Chapleau RR. Development of a mathematical model of anthrax in humans and application to estimate risk to fielded biological threat identification equipment operators. Poster presented at the Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

Strickland J, Zang Q, Paris M, Lehman DM, Kleinstreuer N, Allen D, Choksi N, et al. Multivariate models for prediction of human skin sensitization hazard. Poster presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

Zhou L, Hinerman JM (co-first authors), Blaszczyk M, Miller JLC, Conrady D, Barrow A, Chirgadze D, Bihan D, et al. 2016. Structural basis for collagen recognition by the immune receptor OSCAR. Blood 127(5):529–537; doi: 10.1182/blood-2015-08-667055. PMID: 26552697.

Wheeler MW, Park R, Bailer A, Whittaker C. 2015. Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits. J Occup Environ Hyg 12(sup1):S7-S17; doi: 10.1080/15459624.2015.1076934. PMCID: PMC4685605.

Kirman CR, Proctor DM, Suh M, Hays S. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Thompson CM, Suh M, Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Reddick H., Schaefer, C. Using geographic information systems to model paths from remote villages to the nearest Bolivian health clinics. Texas Public Health Association, Austin, TX, 2015.

Cowan DM, Maskrey JR, Fung E, Woods T, Stabryla L, Scott PK, Finley BL. Evaluation of empirically-based PBPK modeling approaches for modeling ante- and post mortem ethanol concentrations in biological matrices. Poster presentation Society of Toxicology 54^th Annual Meeting, San Diego, CA, 2015.