Publication Topic

Hixon JG, Thompson C, Bichteler A, Abraham L. Smoothing regression splines as the basis for dose-response modeling. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.

Thompson CM, Gaylor DW, Tachovsky JA, Perry C, Carakostas MC, Haws LC. 2013. Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. J Appl Toxicol 33(12):1395-1406; doi: 10.1002/jat.2799. PMID: 22936336.

Wheeler MW, Bailer AJ. 2013. An empirical comparison of low-dose extrapolation from points of departure (PoD) compared to extrapolations based upon methods that account for model uncertainty. Regul Toxicol Pharmacol 67(1):75-82; doi: 10.1016/j.yrtph.2013.06.006. PMCID: PMC4724873

Kirman CR, Aylward LL, Suh M, Harris MA, Thompson CM, Haws LC, Proctor DM, Lin SS, et al. 2013. Physiologically based pharmacokinetic model for humans orally exposed to chromium. Chem Biol Interact 204(1):13-27; doi: 10.1016/j.cbi.2013.04.003. PMID: 23603453.

Kirman CR, Thompson CM, Proctor DM, Suh M, Haws LC, Harris MA, Hays SM. Using PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.

Finley BL, Monnot AD, Gaffney SH, Paustenbach DJ. 2012. Dose-response relationships for blood cobalt concentrations and health effects: A review of the literature and application of a biokinetic model. J Toxicol Environ Health B, 15(8):493–523; doi: 10.1080/10937404.2012.744287. PMID: 23199219.

Kirman CR, Hays SM, Aylward LL, Suh M, Harris MA, Thompson CM, Haws LC, Proctor DM. 2012. Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium. Chem Biol Interact 200(1):45-64; doi: 10.1016/j.cbi.2012.08.016. PMID: 22981460.

Unice KM, Monnot AD, Gaffney SH, Tvermoes BE, Thuett KA, Paustenbach DJ, Finley BL. 2012. Inorganic cobalt supplementation: Prediction of cobalt levels in whole blood and urine using a biokinetic model. Food Chem Toxicol 50(7):2456–2461; doi: 10.106/j.fct.2012.04.009. PMID: 22538081.

Knutsen JS, Kerger BD, Finley BL, Paustenbach DJ. 2012. A calibrated human PBPK model for benzene inhalation with urinary bladder and bone marrow compartments. Risk Anal 33 (7):1237–1251; doi: 10.1111/j.1539-6924.2012.01927.x. PMID: 23278103.

Hinerman JM, Dignam JD, Mueser T. 2012. Models for the binary complex of bacteriophage T4 Gp59 helicase loading protein: G32 single-stranded DNA-binding protein and ternary complex with pseudo-Y junction DNA. J Biol Chem 287(22):8608–8617; doi: 10.1074/jbc.M111.333476. PMID: 22493434.

Mease K, Sane RS, Podila L, Taub ME. 2012. Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: A strategy to assess the interaction of a new chemical entity with P-gp, BCRP and MRP2. J Pharm Sci 101(5):1888–1897; doi: 10.1002/jps.23069. PMID: 22359351.

Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D. 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Thompson C, Perry C, Gaylor D, Tachovsky A, Burkhalter B, Haws L. Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. Presented at Society of Toxicology 50th Annual Meeting, Washington DC, March 2011.

Mueser TC, Hinerman JM, Devos JM, Boyer RA, Williams KJ. 2010. Structural analysis of bacteriophage T4 DNA replication: Review in the Virology Journal series on bacteriophage T4 and its relatives. Virol J 7(Dec 3):359; doi: 10.1186/1743-422X-7-359. PMID: 21129204.

Johns DO, Owens EO, Thompson CM, Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.

Cain WS, Dourson ML, Kohrman-Vincent MJ, Allen BC. 2010. Human chemosensory perception of methyl isothiocyanate: Odor and chemesthesis. Regul Toxicol Pharmacol 58(2):173–180; doi: 10.1016/j.yrtph.2010.06.018. PMID: 20633589.

Garabrant DH, Hong B, Jolliet O, Chen Q, Jiang X, Franzblau A, Lepkowski J, Adriaens P, et al. UMDES results from the linear and logistic regression models. International Society for Exposure Science, Minneapolis, MN, November 2009.

Wheeler MW, Bailer AJ. 2009. Comparing model averaging with other model selection strategies for benchmark dose estimation. Environ Ecol Stat 16:37-51; doi: 10.1007/s10651-007-0071-7.

Thompson CM, Johns DO, Sonawane S, Barton HA, Hattis D, Tardif R, Krishnan K. 2009. Database for physiologically based pharmacokinetic (PBPK) modeling: Physiological parameters for healthy and health-impaired elderly. J Toxicol Environ Health B 12(1):1–24; doi: 10.1080/10937400802545060. PMID: 19117207.

James HR, Barfield L, Britt JK, James RC. 2008. Worker exposure to secondhand smoke: Evaluating a prediction model. Prof Saf 53(9):ASSE-08-09-34.