Publication Topic

Sterner T, Ruark C, Covington T, Gearhart J. Monte Carlo and sensitivity analyses of a PBPK model for the oxime TMB-4. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Las Vegas, NV, November 2011.

Covington T, Robinson P, Gearhart J. Exploring issues in simulating dermal exposure using a physiologically-based pharmacokinetic-pharmacodynamic (PBPK-PD) model for VX. Poster presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

Johns DO, Owens EO, Thompson CM, Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.

Sterner TR, Ruark CD, Covington TR, Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.

Covington T, Robinson P, Gearhart J. Exploring issues in simulating dermal exposure using a physiologically-based pharmacokinetic-pharmacodynamic (PBPK-PD) model for VX. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.

Staskal-Wikoff D, Burkhalter B, Stapleton H, Harris M. PBDEs in Newark Bay sediments. Presented at Dioxin 2010, San Antonio, TX, September 2010.

Thompson CM, Johns DO, Sonawane S, Barton HA, Hattis D, Tardif R, Krishnan K. 2009. Database for physiologically based pharmacokinetic (PBPK) modeling: Physiological parameters for healthy and health-impaired elderly. J Toxicol Environ Health B 12(1):1–24; doi: 10.1080/10937400802545060.

Covington TR, Jakubowski EM, McGuire JM, Evans RA, Hulet SW, Gearhart JM. Accounting for stereo-isomers and ionization in a PBPK/PD model of VX exposure. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2009.

Staskal DF, Birnbaum LS. Screening-level assessment of risk associated with exposure to PBDEs in vehicles. Society for Toxicology 48^th Annual Meeting, Baltimore, MD, March 2009.

DeWoskin RS, Thompson CM. 2008. Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants. Regul Toxicol Pharmacol 51(June):66–86; doi: 10.1016/j.yrtph.2008.02.005.

Teeguarden JG, Bogdanffy MS, Covington TR, Tan C, Jarabek AM. 2008. A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry. Inhal Toxicol 20(4):375–390; doi: 10.1080/08958370801903750.

Gearhart JM, Covington TR, Robinson PJ, Whalley CE, McGuire JM, Evans RA, et al. Simulation of VX exposure in multiple species by means of a physiologically based pharmacokinetic/pharmacodynamic model. Poster presented at the Bioscience Review Conference, Baltimore, MD, May 2008.

Richardson VM, Staskal DF, Ross DG, Diliberto JJ, Devito MJ, Birnbaum LS. 2008. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicol Appl Pharmacol 226(3):244-250; doi: 10.1016/j.taap.2007.09.015.

Staskal DF, Tachovsky JA, Harris MA, Haws LC. 2008. Preliminary evaluation of human health risk associated with exposure to PBDEs in the United States. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Tachovsky JA, Staskal DF, Harris MA, Scott LF, Luksemburg WJ, Paustenbach DP, Haws LC. 2008. Principal components analysis of PBDE concentrations in fish tissue from southern Mississippi. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Thompson CM, Sonawane B, Barton HA, DeWoskin RS, Schlosser P, Lipscomb JC, Chiu W, Krishnan K. 2008. Approaches for applications of physiologically based pharmacokinetic models in risk assessment. J Toxicol Environ Health B 11(7):519–547; doi: 10.1080/10937400701724337.

Diliberto JJ, Staskal DF, Hakk H, Birnbaum LS. Differential urinary protein binding of PBDEs in mice. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.

Emond C, Raymer J, Garner E, Diliberto J, Staskal D, Birnbaum LS. A physiologically-based pharmacokinetic model for developmental exposure to PBDE-47 in rodents. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.

Nguyen LM, Staskal DF, Ferriby LL, Williams ES, Luksemburg WJ, Haws LC, Birnbaum LS, Paustenbach DJ, Harris MA. Dietary intake of PBDEs based on consumption of catfish in southern Mississippi. Society of Toxicology 46^th Annual Meeting, Charlotte, NC, March 2007.

Covington TR, Gentry PR, Van Landingham CB, Andersen ME, Kester JE, Clewell HJ. 2007. The use of Markov chain MonteCarlo uncertainty analysis to support a Public Health Goal for perchloroethylene. Regul Toxicol Pharmacol 47(1):1–18; doi: 10.1080/20024091064264.