Publication Topic

LaPlaca SB, van den Hurk P. Toxicity of a pulsed chronic exposure to crumb rubber particles in mummichog (Fundulus heteroclitus). Platform presentation at 42nd annual meeting of the Society of Environmental Toxicology and Chemistry, North America Chapter, Portland, OR, November 2021.

Black MB, Andersen ME, Pendse SN, Borghoff SJ, Streicker M, McMullen PD. 2021. RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days. Data in Brief 38:107420. doi: 10.1016/j.dib.2021.107420. PMID: 34660856; PMCID: PMC8502903.

Palermo CM, Foreman JE, Wikoff DS, Lea I. 2021. Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development. Curr Res Toxicol 22:2:254–271. doi: 10.1016/j.crtox.2021.07.002. PMID: 34401750; PMCID: PMC8350458.

Gentry R, Rodricks J, Clewell H, Greene T, Chappell G, Lea I, Borghoff S, Yang C, Rathman J, Ribeiro JV, Hobocienski B, Mostrag A. 2021. RE: Response to the Office of Environmental Health Hazard Assessment on comments related to Gentry et al. (2021). Food Chem Toxicol 152:112202. doi: 10.1016/j.fct.2021.112202. Epub 2021 Apr 17. PMID: 33872725.

Gentry R, Greene T, Chappell G, Lea I, Borghoff S, Yang C, Rathman J, Ribeiro JV, Hobocienski B, Mostrag A, Rodricks J, Clewell H. 2021. Integration of evidence to evaluate the potential for neurobehavioral effects following exposure to USFDA-approved food colors. Food Chem Toxicol 151:112097. doi: 10.1016/j.fct.2021.112097. Epub 2021 Mar 4. PMID: 33677041.

Lea IA, Chappell GA, Wikoff DS. 2021. Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence. Mutat Res Genet Toxicol Environ Mutagen 868–869:503389. doi: 10.1016/j.mrgentox.2021.503389. PMID: 34454695.

Heintz MM, Doepker CL, Wikoff DS, Hawks SE. 2021. Assessing the food safety risk of ochratoxin A in coffee: A toxicology-based approach to food safety planning. J Food Sci 86(11):4799-4810; doi: 10.1111/1750-3841.15938.

Barnett LMA, Kramer NE, Buerger AN, Love DH, Bisesi JH, Cummings BS. 2021. Transcriptomic analysis of the differential nephrotoxicity of diverse brominated flame retardants in rat and human renal cells. Int J Mol Sci 22(18):10044.

East A, Isaacs K, Vallero D. Application of the Residential Population Generator (RPGen) in prediction of exposure outcomes for owners and renters from consumer products using the Combined Human Exposure Model (CHEM). Symposium presented at International Society of Exposure Science Annual Meeting, Virtual, September 2021; doi: 10.23645/epacomptox.16632319.

East A, Brady S, Isaacs K, Vallero D. The role of the Product Use Scheduler (PUS) in determining product use categories (PUCs) for owners and renters in the Combined Human Exposure Model (CHEM). Symposium presented at International Society of Exposure Science Annual Meeting, virtual, September 2021; doi: 10.23645/epacomptox.16632271.

Fisher H, East A, Vallero D. Estimating longitudinal aggregate exposure — The third module of CHEM: Source to dose. Symposium presented at International Society of Exposure Science Annual Meeting, virtual conference, September 2021; doi: 10.23645/epacomptox.16630675.

East A, Dawson D, Glen G, Isaacs K, Dionisio K, Price PS, et al. 2021. The Residential Population Generator (RPGen): Parameterization of residential, demographic, and physiological data to model intraindividual exposure, dose, and risk. Toxics 9(11):303; doi: 10.3390/toxics9110303.

Wikoff D, Fitch S, Borghoff S. Case-study applications using evidence-based approaches to assess endocrine activity for risk assessment. Invited speaker (Wikoff):  61^st Annual Meeting (virtual) of the Society for Birth Defects Research & Prevention, June 2021.

Parker JA, Boles C, Buerger AN, Fung ES, Maier A. 2021. Derivation of an occupational exposure limit for β-glucans. Regul Toxicol Pharmacol 123:104959.

Fitch SE, Payne LE, van de Ligt JLG, Doepker C, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Public Health 21(1):956, doi: 10.1186/s12889-021-10934-2.

Borghoff SJ, Fitch SE, Black MVB, McMullen PD, Andersen ME, Chappell GA. 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124(Aug):104977; doi: 10.1016/j.yrtph.2021.104977.

Whaley P, Blaauboer BJ, Brozek J, Cohen Hubal EA, Hair K, Kacew S, Knudsen TB, Kwiatkowski CF, Mellor DT, Olshan AF, Page MJ, Rooney AA, Radke E, Shamseer L, Tsaioun K, Tugwell P, Wikoff D, Woodruff TJ. 2021. Improving the quality of toxicology and environmental health systematic reviews: What journal editors can do. ALTEX 38(3):513-522. doi: 10.14573/altex.2106111.

Yin W, Nie Z, Dingley K, Trzoss M, Krilov G, Marshall N et al. 2021. Characterization of potent paracaspase MALT1 inhibitors for hematological malignancies. Blood 138 (Supplement 1):1187; doi: 10.1182/blood-2021-153159.

Jaeschke H, Murray FJ, Monnot AD, Jacobson-Kram D, Cohen SM, Hardisty JF, Atillasoy E… Wikoff D, et al. 2021. Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential. Regul Toxicol Pharmacol 120(March):104859; doi: 10.1016/j.yrtph.2020.104859. PMID: 33388367.

Proctor DM, Bhat V, Suh M, Reichert H, Jiang X, Thompson CM. 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124(August):104969; doi: 10.1016/j.yrtph.2021.104969.