Publication Topic

Barnett LMA, Kramer NE, Buerger AN, Love DH, Bisesi JH, Cummings BS. 2021. Transcriptomic analysis of the differential nephrotoxicity of diverse brominated flame retardants in rat and human renal cells. Int J Mol Sci 22(18):10044; doi: 10.3390/ijms221810044. PMID: 34576211.

Tate T, Wambaugh J, Patlewicz G, Shah I. 2021. Repeat-dose toxicity prediction with Generalized Read-Across (GenRA) using targeted transcriptomic data: A proof-of-concept case study. Comput Toxicol 19(Aug):100171; doi: 10.1016/j.comtox.2021.100171. PMID: 37309449.

Chappell GA, Heintz MM, Haws LC. 2021. Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development. Curr Res Toxicol 2:30–41; doi: 10.1016/j.crtox.2021.01.003.

Chappell GA, Thompson CM, Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.

Klaren WD, Ring C, Harris MA, Thompson CM, Borghoff S, Sipes NS, Hsieh JH, Auerbach SS, Rager JE. 2019. Identifying attributes that influence in vitro-to-in vivo concordance by comparing Tox21 bioactivity versus DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci 167(1):157–171; doi: 10.1093/toxsci/kfy220. PMID: 30202884.

LaPlaca SB. Identification and toxicity of compounds associated with tire wear particles in fathead minnow and mummichog. Platform presentation at Pollutant Response in Marine Organism (PRIMO) symposium, Charleston, SC, May 2019.

Rager JE, Suh M, Chappell G, Thompson CM, Proctor DM. 2019. Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis. Toxicol Lett 305(May 1):40-50; doi: 10.1016/j.toxlet.2019.01.011. PMID: 30690063.

Chappell GA, Rager JE, Wolf JC, Babic M, LeBlanc KJ, Ring CL, Harris MA, Thompson C. Similarities in the transcriptomic signatures in the duodenum of mice exposed to hexavalent chromium, captan, or folpet inform the mechanisms of chemical-induced mouse small intestine cancer. Presentation at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

Lavelle C, Smith LC, Bisesi JH, Yu F, Silva-Sanchez C, Moraga-Amador D, Buerger AN, et al. 2018. Tissue-based mapping of the fathead minnow (Pimephales promelas) transcriptome and proteome. Front Endocrinol 9:611; doi: 10.3389/fendo.2018.00611.

Jackson MA, Yang L, Lea I, Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535; doi: 10.1002/em.22114. PMID: 28766826.

Rager JE, Ring CL, Fry RC, Suh M, Proctor DM, Haws L, Harris MA, Thompson CM. 2017. High-throughput screening data interpretation in the context of in vivo transcriptomic responses to oral Cr(VI) exposure. Toxicol Sci 158(1):199–212; doi: 10.1093/toxsci/kfx085. PMID: 28472532.

Rager JE, Thompson CM, Ring C, Fry RC, Harris MA. Integration of transcriptomics and high-throughput screening predictions with robust in vivo data to inform hexavalent chromium mode of action. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

Thompson CM, Rager JE, Suh M, Ring CL, Proctor DM, Haws LC, Fry RC, Harris MA. 2016. Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment. Environ Molec Mutagen 57(9):706-716; doi: 10.1002/em.22064.

Bi P, Yue F, Sato Y, Wirbisky S, Liu W, Shan T, Wen Y, Zhou D, Freeman J, Kuang S. 2016. Stage-specific effects of notch activation during skeletal myogenesis. Elife 5(Sep 19):e17355; doi: 10.7554/eLife.17355. PMID: 27644105.

Wirbisky SE, Damayanti NP, Mahapatra CT, Sepúlveda MS, Irudayaraj J, Freeman JL. 2016. Mitochondrial dysfunction, disruption of F-actin polymerization, and transcriptomic alterations in zebrafish larvae exposed to trichloroethylene. Chem Res Toxicol 29(2):169–179; doi: 10.1021/acs.chemrestox.5b00402.

Budinsky R, Urban J, Rowlands JC. 2011. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator gene. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

Woods CG, Burns AM, Bradford BU, Threadgill DW, Cunningham ML, Rusyn I. The role of differences in expression of PPARalpha between mouse strains in pleotropic response to peroxisome proliferators. Abstract 627, Society of Toxicology 46^th Annual Meeting, Charlotte, NC, March 2007.

Rogers JM. 2006. Casting a broad network: Fishing for mechanisms of retinoid teratogenicity. Toxicological highlight. Toxicol Sci 94(1):1–2; doi: 10.1093/toxsci/kfl104.

Peters JM, Aoyama T, Burns AM, Gonzalez FJ. 2003. Bezafibrate is a dual ligand for PPARalpha and PPARbeta: Studies using null mice. Biochim Biophys Acta 1632(1-3):80-89; doi: 10.1016/s1388-1981(03)00065-9. PMID: 12782154.

Newbound GC, O’Rourke JP, Collins ND, Andrews JM, DeWille J, Lairmore MD. 2000. Repression of tax-mediated human T-lymphotropic virus type 1 transcription by inducible cAMP early repressor (ICER) protein in peripheral blood mononuclear cells. J Med Virol 62(2):286–292; doi: 10.1002/1096-9071(200010)62:2<286::AID-JMV22>3.0.CO;2-Y.  PMID: 11002260.