Publication Year

Klaren WD, Ring C, Harris MA, Thompson CM, Borghoff S, Sipes NS, Hsieh JH, Auerbach SS, Rager JE. 2019. Identifying attributes that influence in vitro-to-in vivo concordance by comparing Tox21 bioactivity versus DrugMatrix transcriptomic responses across 130 chemicals. Toxicol Sci 167(1):157–171; doi: 10.1093/toxsci/kfy220. PMID: 30202884.

Rager JE, Suh M, Chappell G, Thompson CM, Proctor DM. 2019. Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis. Toxicol Lett 305(May 1):40-50; doi: 10.1016/j.toxlet.2019.01.011. PMID: 30690063.

Wikoff DS, Rager JE, Chappell GA, Fitch S, Haws L, Borghoff SJ. 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335; doi: 10.1093/toxsci/kfy279. PMID: 30423162.

Brodsky MB, Levy MJ, Jedlanek E, Pandian V, Blackford B, Price C, et al. 2018. Laryngeal injury and upper airway symptoms after oral endotracheal intubation with mechanical ventilation during critical care: A systematic review. Crit Care Med 46(12):2010–2017; doi: 10.1097/CCM.0000000000003368. PMID: 30096101.

Garabrant DH, Pastula ST. 2018. A comparison of asbestos fiber potency and elongate mineral particle (EMP) potency for mesothelioma in humans. Toxicol Appl Pharmacol 361(15 Dec):127–136; doi: 10.1016/j.taap.2018.07.003. PMID: 30077661.

Barlow CA, Marsh GM, Benson S, Finley BL. 2018. The mineralogy and epidemiology of cosmetic talc. Toxicol Appl Pharmacol 361(Dec 15):173; doi: 10.1016/j.taap.2018.05.036. PMID: 29859223.

Kovochich M, Finley BL, Novick R, Monnot AD, Donovan E, Unice KM, Fung ES, Fung D, Paustenbach DJ. 2018. Understanding outcomes and toxicological aspects of second-generation metal-on-metal hip implants: A state-of-the-art review. Crit Rev Toxicol 48(10):839–887; doi: 10.1080/10408444.2018.1563048. PMID: 30912993.

Robison TW. Extractables and leachables: Outline of current regulatory framework – Challenges and uncertainties. Webinar presentation to Turkish Regulatory Authority and Pharmaceutical Association, December 2018.

Wikoff D. Problem formulation: Lessons and tools from practical applications involving systematic review of mechanistic data. Presented at Strategies and Tools for Conducting Systematic Reviews of Mechanistic Data to Support Chemical Assessments, National Academies of Sciences, Engineering, and Medicine, Washington, DC, December 2018.

Urban J, Wikoff D, Haws L, Fitch S, Ring C, Thompson C, Suh M. 2018. Systematic review protocol: Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count. Zenodo. http://doi.org/10.5281/zenodo.1636357.

Kimzey AL, Piche M-S, Wood M, Weir AB, Lansita J. 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3^rd Ed. Vol 11:399–427.

Brorby G, Ring C, Loko F, Harris MA. Characterization of hexavalent chromium and total chromium in drinking water monitoring data. Poster MP 117, Society of Environmental Toxicology and Chemistry (SETAC) North America 39^th Annual Meeting, Sacramento, CA, November, 2018.

Frankenfeld CL. Residential segregation and health disparities. George Mason University Health Administration Policy/Center for Health Policy, Research, and Ethics Seminar, November 28, 2018.

Tsaioun K, Dirven H, Beck Færden K, Wikoff D, Ram R, Kleinstreuer N, McCormack A, Wright R, Vist GE, Fitch S. 2018. Systematic reviews of the hepatotoxic effects of specified compounds/drugs as observed in humans and experimental animals (rats, mice, dogs and non-human primates). PROSPERO CRD42018112353.

Svensson F, Zoufir A, Mahmoud S, Afzal AM, Snit S, Giblin KA, Clements PJ,…, Greene N, et al. 2018. Information-derived mechanistic hypotheses for structural cardiotoxicity. Chem Res Toxicol 31(11):1119-1127; doi: 10.1021/acs.chemrestox.8b00159. PMID: 30350600.

Kleinstreuer NC, Karmaus A, Mansouri K, Allen D, Fitzpatrick J, Patlewicz G. 2018. Predictive models for acute oral systemic toxicity: A workshop to bridge the gap from research to regulation. Comput Toxicol 8(11):21-24; doi: 10.1016/j.comtox.2018.08.002. PMID: 30320239.

Helman G, Shah I, Patlewicz G. 2018. Extending the Generalized Read-Across approach (GenRA): A systematic analysis of the impact of physicochemical property information on read-across performance. Comput Toxicol 8(Nov):34-50; doi: 10.1016/j.comtox.2018.07.001. PMID: 31667446.

Borghoff SJ, Fitch S, Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99(Nov):168–181; doi: 10.1016/j.yrtph.2018.09.001. PMID: 30240830.

Adamovsky O, Buerger AN, Wormington AM, Ector N, Griffitt RJ, Bisesi JH, et al. 2018. The gut microbiome and aquatic toxicology: An emerging concept for environmental health. Environ Toxicol Chem 37(11):2758–2775; doi: 10.1002/etc.4249. PMID: 30094867.

Heintz MM, Kumar R, Baldwin WS. Cyp2b-null male mice are susceptible to high-fat diet-induced obesity due to changes in PUFA metabolism and response to hepatic lipids as measured by RNAseq. American College of Toxicology, 39th Annual Meeting, West Palm Beach, FL, November 2018.