2011 (33 POSTS)
Hinerman J , Herr A. Determining the mechanism of activation of glycoprotein VI. Poster presented to the Ohio Valley Crystallographic Symposium Meeting, Cleveland, OH, November 2011.
Topics: Toxicology
Haws L, Proctor D, Thompson C , Harris M. 2011. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.
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Topics: Hexavalent Chromium
Henderson RG , Cappellini D, Seilkop S, Oller A, Bates H. Bioaccessibility-based read-across assessment of nickel compounds for oral systemic toxicity. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: Metals , nickel , Toxicology
Kim S, Thompson CM , Kopec AK, Harris MA, Zacharewski TR. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at Society of Toxicology 50th Annual Meeting, Washington, D.C., March 2011.
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Topics: chromium , Hexavalent Chromium
Proctor D, Haws L , Thompson C , Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, March 6-10, 2011, Washington, D.C.
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Topics: Cancer , Hexavalent Chromium , pharmacokinetics , risk assessment
Proctor D, Meek B. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, March 6-10, Washington, DC, March 2011.
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Topics: Cancer , chromium , Hexavalent Chromium , risk assessment
Staskal-Wikoff D , Budinsky R, Rowlands JC. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: Toxicology
2010 (22 POSTS)
Yong M, Kuehn C, Kelsh M , Mitchell M , et al. Associations between platelet count and survival and disease progression in thrombocytopenic patients with myelodysplastic syndromes. Presented at the American Society of Hematology, Orlando, FL, December 2010
Topics: Epidemiology
Robison TW . Genotoxic impurity guidance – Current experiences, FDA perspective. USP Annual Meeting, New Orleans, LA, December 2010.
Topics: genotoxicity
Harris M, Tachovsky JA, Staskal-Wikoff D , Aylward L, Burkhalter B, Simon T, Haws L . Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, San Antonio, TX, September 2010.
Topics: dioxin
Sterner TR, Ruark CD, Covington TR , Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: Toxicology
Makley M, Ruark C, Covington T , Robinson P, Gearhart J. Route of entry model for predicting chemical warfare agent miosis. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: Toxicology
Covington T , Robinson P, Gearhart J. Exploring issues in simulating dermal exposure using a physiologically-based pharmacokinetic-pharmacodynamic (PBPK-PD) model for VX. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: Toxicology
Harris M, Tachovsky JA, Staskal-Wikoff D , Simon T, Burkhalter B, Urban J , Haws L . 2010. Assessment of the impact of various soil cleanup levels on serum concentrations of dioxin-like compounds in humans. Presented at Society of Toxicology 49th Annual Meeting, Salt Lake City, Utah, March 2010.
Topics: dioxin
Robison TW . Dealing with positive in vitro mammalian cell genotoxicity assays. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.
Topics: genotoxicity
Robison TW . Dealing with genotoxic impurities from a regulatory perspective. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.
Topics: genotoxicity
Robison TW . Assessing genotoxic impurities. DIA Meeting (Early drug development: Navigating the treacherous rapids). Bethesda, MD, October 2010
Topics: genotoxicity
Haws L . Biomonitoring – A tool for assessing community exposures to air toxics. Presented at the Air Quality 2010 Conference, University of Texas School of Law, November 2010.
Topics: Air Quality , community health , Exposure Assessment , Toxicology
Haws L, Tachovsky JA, Staskal-Wikoff D , Aylward L, Burkhalter B, Urban J , Simon T, Harris M. An evaluation of the influence of different soil cleanup levels on the concentration of dioxin-like compounds in human serum. Presented at Dioxin 2010, San Antonio, TX, September 2010.
Topics: dioxin , Exposure Assessment
Haws L . Biomonitoring: The circle of life. Presented in the Oil and Gas special session, 22nd Annual Texas Environmental Superconference, Austin, TX, August 2010.