2011 (41 POSTS)
Proctor D, Haws L , Thompson C , Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: Cancer , chromium , mode of action , pharmacokinetics , risk assessment
Proctor D, Meek B. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: Cancer , chromium , mode of action , risk assessment , water
Staskal-Wikoff D , Budinsky R, Rowlands JC. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
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Topics: toxicokinetics
2010 (25 POSTS)
Yong M, Kuehn C, Kelsh M , Mitchell M , et al. Associations between platelet count and survival and disease progression in thrombocytopenic patients with myelodysplastic syndromes. Presented at the American Society of Hematology, Orlando, FL, December 2010.
Topics: Epidemiology
Robison TW . Genotoxic impurity guidance – Current experiences, FDA perspective. USP Annual Meeting, New Orleans, LA, December 2010.
Topics: genotoxicity
Tachovsky JA, Haws L . Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI. Presented at the Society for Risk Analysis Annual Meeting, Salt Lake City, UT, December 2010.
Topics: dioxin
Harris M, Tachovsky JA, Staskal-Wikoff D , Aylward L, Burkhalter B, Simon T, Haws L . Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, San Antonio, TX, September 2010.
Topics: dioxin
Sterner TR, Ruark CD, Covington TR , Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: modeling , PBPK/PBDE
Makley M, Ruark C, Covington T , Robinson P, Gearhart J. Route of entry model for predicting chemical warfare agent miosis. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: modeling
Covington T , Robinson P, Gearhart J. Exploring issues in simulating dermal exposure using a physiologically-based pharmacokinetic-pharmacodynamic (PBPK-PD) model for VX. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Topics: PBPK/PBDE , pharmacokinetics
Harris M, Tachovsky JA, Staskal-Wikoff D , Simon T, Burkhalter B, Urban J , Haws L . 2010. Assessment of the impact of various soil cleanup levels on serum concentrations of dioxin-like compounds in humans. Presented at Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, March 2010.
Topics: dioxin
Robison TW . Dealing with positive in vitro mammalian cell genotoxicity assays. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.
Topics: genotoxicity
Robison TW . Dealing with genotoxic impurities from a regulatory perspective. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.
Topics: genotoxicity
Robison TW . Assessing genotoxic impurities. DIA Meeting (Early drug development: Navigating the treacherous rapids). Bethesda, MD, October 2010
Topics: genotoxicity
Haws L . Biomonitoring – A tool for assessing community exposures to air toxics. Presented at the Air Quality 2010 Conference, University of Texas School of Law, November 2010.
Topics: Air Quality , community health , Exposure Assessment
Haws L, Tachovsky JA, Staskal-Wikoff D , Aylward L, Burkhalter B, Urban J , Simon T, Harris M. An evaluation of the influence of different soil cleanup levels on the concentration of dioxin-like compounds in human serum. Presented at Dioxin 2010, San Antonio, TX, September 2010.
Topics: dioxin , Exposure Assessment
Haws L . Biomonitoring: The circle of life. Presented in the Oil and Gas special session, 22nd Annual Texas Environmental Superconference, Austin, TX, August 2010.
Topics: Epidemiology
Burrows-Sheppard AM , Willems SS, Heitfeld FA, Treichel JL, Raabe H, Curren R. An evaluation of the EpiDerm Corrosivity and Corrositex Assays for predicting skin corrosivity of chemical products with extreme alkaline pH. Abstract #489, Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, 2010.
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Topics: chemical safety assessment , personal care products
Panko JM , Kreider ML, Ferrara J. REACH – A review of the regulation and technical components of registration. AIHA Pittsburgh Section, Pittsburgh, PA, February, 2010.
Topics: regulatory toxicology
Staskal-Wikoff D, Burkhalter B, Stapleton H, Harris M. PBDEs in Newark Bay sediments. Presented at Dioxin 2010, San Antonio, TX, September 2010.