2023 (63 POSTS)
Wright PSR, Smith GF, Briggs KA, Thomas R, Maglennon G, Mikulskis P, Chapman M, Greene N , et al. 2023. Retrospective analysis of the potential use of virtual control groups in preclinical toxicity assessment using the eTOX database. Regul Toxicol Pharmacol 138(Feb):105309; doi: 10.1016/j.yrtph.2022.105309 . PMID: 36481280.
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Topics: drug development , modeling
Houck K, Paul Friedman K, Feshuk M, Patlewicz G , Smeltz M, Clifton S, Wetmore BA, Velichko S, et al. 2023. Evaluation of 147 perfluoroalkyl substances for immunotoxic and other (patho)physiological activities through phenotypic screening of human primary cells. ALTEX 40(2):248–270; doi: 10.14573/altex.220304 . PMID: 36129398.
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Topics: chemical safety assessment , PFAS
Adams M, Hilde H, Chang D, Richard A, Williams AJ, Shah I, Patlewicz G . 2023. Development of a CSRML version of the Analog Identification Methodology (AIM) fragments and their evaluation within the Generalized Read-Across (GenRA) approach. Comput Toxicol 25(Feb):100256; doi: 10.1016/j.comtox.2022.100256 . PMID: 36733411.
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Topics: NAMs
Wheeler MW , Lim S, House JS, Shockley KR, Bailer AJ, Fostel J, Yang L, Talley D, Raghuraman A, Gift JS. 2023. ToxicR: A computational platform in R for computational toxicology and dose–response analyses. Comp Toxicol 25(Feb):100259; doi: 10.1016/j.comtox.2022.100259 . PMID: 36909352.
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Topics: benchmark dose estimation (BMD)
Bullano M, Cool C, Schultz BG, Durgapal S, Sacks N , Liu Y , Kee R, Batt K. 2023. Evaluating the financial impact of utilizing recombinant porcine factor VIII or recombinant FVIIa for patients with acquired hemophilia A. Expert Rev Phamacoecon Outcomes Res 23(2):225-230; doi: 10.1080/14737167.2023.2160705 . PMID: 36537696.
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Topics: Health Economics and Outcomes Research (HEOR)
East A , Dawson DE, Brady S, Vallero DA, Tornero-Velez R. 2023. A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models. Toxics 11(2):163; doi: 10.3390/toxics11020163 . PMID: 36851038.
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Topics: modeling , PFAS , scoping review , toxicokinetics
Grover A, Sankaranarayanan S, Mathur V, Suri P, Qiu H, Andrews-Zwilling Y, Mease K , Taylor LK, et al. 2023. Pharmacokinetic and target engagement measures of ANX007, an anti-C1q antibody fragment, following intravitreal administration in nonhuman primates. Invest Opthalmol Visual Sci 64(2)3; 10.1167/iovs.64.2.3 . PMID: 36729444.
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Topics: pharmacokinetics
Boyce M, Favela KA, Bonzo JA, Chao A, Lizarraga L, Moody LR, Owens EO, Patlewicz G , et al. 2023. Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis. Front Toxicol 5(Jan 18):1051483; doi: 10.3389/ftox.2023.1051483 . PMID: 36742129.
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Topics: spectrometry
Lizarraga L, Suter GW, Lambert JC, Patlewicz G , Zhao JQ, Dean JL, Kaiser P. 2023. Advancing the science of a read-across framework for evaluation of data poor chemicals incorporating systematic and new approach methods. Regul Toxicol Pharm 137(Jan):105293; doi: 10.1016/j.yrtph.2022.105293 . PMID: 36414101.
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Topics: NAMs
Borghoff SJ , Cohen SS, Jiang X , Lea IA , Klaren WD , Chappell GA, Britt JK , Rivera BN, Choksi NY , Wikoff DS . 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549 . PMID: 36493943.
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Topics: carcinogens , food safety , Food science , Systematic Review
2022 (95 POSTS)
Doepker C, Movva N, Cohen SS, Wikoff DS . 2022. Benefit-risk of coffee consumption and all-cause mortality: A systematic review and disability adjusted life year analysis. Food Chem Toxicol 170(Dec):113472; doi: 10.1016/j.fct.2022.113472 . PMID: 36243217.
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Topics: Food science , Systematic Review
Boles C, Zisook R, Buerger AN , Hamaji C, Mathis C, Lauer D, et al. 2022. Semi-quantitative microbial risk assessment: A narrative review and proposed framework for health and safety practitioners. J Pub Health Emerg 6(Dec 25):34; doi: 10.21037/jphe-22-1 .
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Topics: COVID-19 , risk assessment
Broome CM, Hooda N , Su J, Jiang X , Nicholson G, Frankenfeld CL , Iglesias-Rodriguez M, Fryzek J, Patel Parija. 2022. Medically-attended anxiety and depression is increased among newly diagnosed patients with cold agglutinin disease: Analysis of an integrated claim-clinical cohort in the United States. PLoS One 17(12):e0276617; doi: 10.1371/journal.pone.0276617 . PMID: 36520848.
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Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Sampedro F , Pérez-Rodríguez F, Servadio JL, Gummalla S, Hedberg CW. 2022. Quantitative risk assessment model to investigate the public health impact of varying Listeria monocytogenes allowable levels in different food commodities: A retrospective analysis. Int J Food Microbiol 383(Dec 16):109932 doi: 10.1016/j.ijfoodmicro.2022.109932 . PMID: 36182750.
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Topics: food safety , Food science , risk assessment
Dhar SI, Ryan MA, Davis AC, Jedlanek E, Pietsch K, Price C , et al. 2022. Does medialization improve swallowing function in patients with unilateral vocal fold paralysis? A systematic review. Dysphagia 37(6):1769–1776; doi: 10.1007/s00455-022-10441-5 . PMID: 35412149.
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Topics: Systematic Review
Kato Y, Lim AY, Sakolish C, Valdiviezo A, Moyer HL , Hewitt P, Bajaj P, Han G, Rusyn I. 2022. Analysis of reproducibility and robustness of OrganoPlate® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs. Toxicol in Vitro 85(Dec):105464; doi: 10.1016/j.tiv.2022.105464 . PMID: 36057418.
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Topics: pharmacokinetics
Leslie TF, Frankenfeld CL , Menon N. 2022. Disparities in colorectal cancer time-to-treatment and survival time associated with racial and economic residential segregation surrounding the diagnostic hospital, Georgia 2010–2015. Cancer Epidemiol 81(Dec):102267; doi: 10.1016/j.canep.2022.102267 . PMID: 36166941.
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