2018 (42 POSTS)
Revollo JR, Pearce MG, Dad A, Petibone DM, Robison TW , Roberts D, Dobrovolsky VN. 2018. Analysis of mutation in the rat Pig-a assay: I) Studies with bone marrow erythroid cells. Environ Mol Mutagen 59(8):722-732; doi: 10.1002/em.22211 .
View Abstract
Topics: flow cytometry
Moffat I, Martinova N, Seidel C, Thompson CM . 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044 .
View Abstract
Topics: chromium , water
Klaren WD , Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342; doi: 10.1089/adt.2018.86 . PMID: 30070899.
View Abstract
Topics: Toxicology
Powles MA, Galgoci A, Misura A, Colwell L, Dingley K , Tang W, et al. 2018. In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models. Antimicrob Agents Chemother 62:e02577–17; doi: 10.1128/AAC.02577-17 . PMID: 29866878.
View Abstract
Topics: Toxicology
Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, … Dingley KH , et al. 2018. Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists. ACS Med Chem Lett (9):1088–1093; doi: 10.1021/acsmedchemlett.8b00306 . PMID: 30429950.
View Abstract
Topics: Toxicology
Fung ES, Unice KM, Paustenbach DJ, Finley BL , Kovochich M. 2018. Methods for sterilizing clinically relevant wear particles isolated from metal-on-metal hip implants. Sci Rep 8(1):2384; doi: 10.1038/s41598-017-18239-4 .
View Abstract
Topics: Metals
Kovochich M, Finley BL , Novick R, Monnot AD, Donovan E, Unice KM, Fung ES, Fung D, Paustenbach DJ. 2018. Understanding outcomes and toxicological aspects of second-generation metal-on-metal hip implants: A state-of-the-art review. Crit Rev Toxicol 48(10):839–887.
View Abstract
Topics: Metals
Sacks NC , Sharma A, Cyr PL , Bertiger G, Dahdal DN, Brogadir S. 2018. Real-world comparison of the effectiveness and safety of different bowel preparation agents. Clin Exp Gastroenterol 11:289–299; doi: 10.2147/CEG.S171861 .
View Abstract
Topics: Epidemiology
Sacks NC , Cyr PL , Louie AC, Liu Y , Chiarella MT, Sharma A, Chung KC. 2018. Burden of acute myeloid leukemia among older, newly diagnosed patients: Retrospective analysis of data from the 2010-2012 Medicare limited data set. Clin Ther 40(5):692–703.e2; doi: 10.1016/j.clinthera.2018.03.012 .
View Abstract
Topics: Cancer , Health Economics and Outcomes Research (HEOR)
Wikoff DS , Miller GW. 2018. Systematic reviews in toxicology (Editorial). Toxicol Sci 163(2):335–337; doi: 10.1093/toxsci/kfy109 .
View Abstract
Topics: Systematic Review
Ruzin A, Pastula ST , Levin-Sparenberg EM, Jiang X, Fryzek JP, Tovchigrechko A, Lu B, Qi Y, Liu H, Jin H, Yu L, Hackett J, Villafana T, Esser MT. 2018. Characterization of circulating RSV strains among subjects in the OUTSMART-RSV surveillance program during the 2016-17 winter viral season in the United States. PLoS One 13(7):e0200319; doi: 10.1371/journal.pone.0200319 .
View Abstract
Topics: Epidemiology
Garabrant DH, Pastula ST . 2018. A comparison of asbestos fiber potency and elongate mineral particle (EMP) potency for mesothelioma in humans. Toxicol Appl Pharmacol 361(15 Dec):127–136; doi: 10.1016/j.taap.2018.07.003 .
View Abstract
Topics: asbestos , Epidemiology
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96:178–189; doi: 10.1016/j.yrtph.2018.05.006 .
View Abstract
Topics: carcinogens , mode of action , risk assessment
Suh M , Proctor DM , Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006 .
View Abstract
Topics: carcinogens , chemical safety assessment , consumer products
Proctor DM , Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol, 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016 .
View Abstract
Topics: Adverse outcome pathways (AOPs) , Cancer , genotoxicity
Thompson CM , Kirman CR, Hays SM, Suh M , Harvey SE , Proctor DM , Rager JE, Haws LC , Harris MA. 2018. Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium. J Appl Toxicol 38:351–365. doi: 10.1002/jat.3545 .
View Abstract
Topics: chromium , pharmacokinetics
Pecquet AM, Martinez JM, Vincent M , Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878, doi: 10.1002/jat.3594.
View Abstract
Topics: Toxicology
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415; doi: 10.1080/10408444.2018.1430121 .
View Abstract
Topics: benchmark dose estimation (BMD) , modeling
Wikoff D (contributing author), EFSA (European Food Safety Authority), EBTC (Evidence-Based Toxicology Collaboration). 2018. EFSA Scientific Colloquium 23. Evidence integration in risk assessment: The science of combining apples and oranges. EFSA Supporting Publication 2018:15(3):1396; doi: 10.2903/sp.efsa.2018.EN-1396 .
View Abstract
Topics: risk assessment
Caballero-Gallardo K, Wirbisky-Hershberger S , Olivero-Verbel J, de la Rosa J, Freeman JL. 2018. Embryonic exposure to an aqueous coal dust extract results in gene expression alterations associated with development and function of connective tissue and the hematological system, immunological and inflammatory disease and cancer in zebrafish. Metallomics 10(3):463–473
View Abstract