2018 (41 POSTS)
Rish W , Pfau EJ. 2018. Bounding analysis of drinking water health risks from a spill of hydraulic fracturing flowback water. Risk Analysis 38(4):724-754; doi: 10.1111/risa.12884 .
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Topics: Environmental Science , fracking , risk assessment , Toxicology
2017 (53 POSTS)
Wheeler MW , Dunson DB, Herring AH. 2017. Bayesian local extremum splines. Biometrika 104(4):939-52; doi: 10.1093/biomet/asx039 . PMCID: PMC5798493.
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Topics: Bayesian modeling
Lansita J, Mease KM , Qiu H, Yednock T, Sankaranarayanan S, Kramer S. 2017. Nonclinical development of ANX005: A humanized anti-Clq antibody for treatment of autoimmune and neurodegenerative diseases. Int J Toxicol 36(6)449-462; doi: 10.1177/1091581817740873 . PMID: 29202623.
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Topics: Toxicology
Wheeler MW , Bailer AJ, Cole T, Park RM, Shao K. 2017. Bayesian quantile impairment threshold benchmark dose estimation for continuous endpoints. Risk Anal 37(11):2107-18; doi: 10.1111/risa.12762 . PMCID: PMC5740488.
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Topics: Bayesian modeling , benchmark dose estimation (BMD) , modeling
Wirbisky-Hershberger SE , Sanchez OF, Horzmann KA, Thanki D, Yuan C, Freeman JL. 2017. Atrazine exposure decreases the activity of DNMTs, global DNA methylation levels, and dnmt expression. Food Chem Toxico l 109:727–734.
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Topics: Toxicology
Monticello TM , Jones TW, Dambach DM, Potter DM, Bolt MW, Liu M, Keller DA, Hart TK, et al. 2017. Current nonclinical testing paradigm enables safe entry to First-in-Human clinical trials: The IQ consortium nonclinical translational database. Toxicol Appl Pharmacol 334(Nov 1):100-109; doi: 10.1016/j.taap.2017.09.006 .
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Topics: nonclinical safety assessment
Huddle MG, Goman AM, Kernizan FC, Foley DM, Price C , Frick KD, Lin FR. 2017. The economic impact of adult hearing loss: A systematic review. JAMA Otolaryngol: Head Neck Surg 143(10):1040–1048; doi: 10.1001/jamaoto.2017.1243 .
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Topics: hearing loss , Systematic Review
Shao K, Allen BC, Wheeler MW . 2017. Bayesian hierarchical structure for quantifying population variability to inform probabilistic health risk assessments. Risk Anal 37(10):1865-78; doi: 10.1111/risa.12751 .PMCID: PMC6151353.
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Topics: Bayesian modeling , risk assessment
Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C , Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; doi: 10.1021/acs.chemrestox.7b00221 .
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Topics: arsenic , Toxicology
Thompson CM, Suh M, Proctor DM, Haws LC , Harris MA. 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutation Res 823:45-57.
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Topics: Hexavalent Chromium
Thompson CM , Young RR, Dinesdurage H, Suh M , Harris MA, Rohr AC, Proctor DM . 2017. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of Big Blue® rats. Toxicol Appl Pharmacol 330(1):48-52; 10.1016/j.taap.2017.07.002 .
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Topics: chromium , Cr(VI) MOA Study , Hexavalent Chromium
Iwata Y, Klaren WD , Lebakken CS, Grimm FA, Rusyn I. 2017. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay Drug Dev Technol 15(6):267–279; doi; 10.1089/adt.2017.786 . PMID: 28771372.
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Topics: Toxicology
Klaren WD , Vine D, Vogt S, Robertson LW. 2017. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433; doi:10.1007/s11356-017-0202-0 .
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Topics: Metals , PCBs , Toxicology
Panko J , Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. A comparative evaluation of five hazard screening tools. Integr Environ Assess Manag 13(1):139–154.
See also: Panko J , Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. Letter to the Editor: Authors’ response to Turner et al. Integr Environ Assess Manag 13(1):15–16.
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Topics: Toxicology
Perez AL, Gauthier AM, Ferracini T, Cowan DM, Kingsbury T, Panko J . 2017. The challenge of predicting problematic chemicals using a decision analysis tool: Triclosan as a case study. Integr Environ Assess Manag 13(1):198–207; doi: 10.1002/ieam.1778 .
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Topics: Toxicology , triclosan
Burns A, Shin J, Unice KM, Gaffney SH, Kreider ML, Gelatt RN, Panko JM . 2017. Combined analysis of job and task benzene air exposures among workers at four US refinery operations. Toxicol Indust Health 33(3):193–210; doi: 10.1177/0748233715619072 .
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Topics: benzene , Occupational , Toxicology
Wang Y, Villalta PW, Peng L, Dingley KH , Malfatti MA, Turteltaub KW, Turesky RJ. 2017. Mass spectrometric characterization of an acid-labile adduct formed with 2-amino-1-methyl-phenylimidazo[4,5-b]pyridine and albumin in humans. Chem Res Toxicol 30(2):705–714; doi: 10.1021/acs.chemrestox.6b00426 . PMID: 27984695.
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Topics: carcinogens
Harper BH, Wang L, Zhu C, Kar NF, Li B, Moyes CR, … Dingley K , et al. 2017. Investigation of piperazine benzamides as human β3 adrenergic receptor agonists for the treatment of overactive bladder. Bioorg Med Chem Lett 27(4):1094–1098; doi: 10.1016/j.bmcl.2016.12.033 . PMID: 28089699.
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