2016 (155 POSTS)
Thompson CM , Suh M , Mittal L , Wikoff D , Welsh B, Proctor DM . 2016. Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations. Regul Toxicol Pharmacol 80(Oct):60-70; doi: 10.1016/j.yrtph.2016.05.031 . PMID: 27233922.
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Publication: Manuscripts
/ Topics: Air Quality , mode of action , Systematic Review , titanium dioxide
Roberts DW, Api AM, Patlewicz G , Schultz TW. 2016. Chemical applicability domain of the Local Lymph Node Assay (LLNA) for skin sensitization potency. Part 1. Underlying physical organic chemistry principles and the extent to which they are represented in the LLNA validation dataset. Regul Toxicol Pharmacol 80(Oct):247-254; doi: 10.1016/j.yrtph.2016.07.007 . PMID: 27424000.
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Publication: Manuscripts
/ Topics: computational toxicology
Alexander DD, Yan J, Bylsma LC , Northington RS, Grathwohl D, Steenhout P, Erdmann P, Spivey-Krobath E, Haschke F. 2016. Growth of infants consuming whey-predominant term infant formulas with a protein content of 1.8 g/100 kcal: A multicenter pooled analysis of individual participant data. Am J Clin Nutr 104(4):1083-1092; doi: 10.3945/ajcn.116.130633 . PMID: 27604774.
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Publication: Manuscripts
/ Topics: nutrition
Tvermoes BE, Unice KM, Winans B, Kovochich M, Christian WV, Donovan E, Fung ES, Finley BL , et al. 2016. A preliminary evaluation of immune stimulation following exposure to metal particles and ions using the mouse popliteal lymph node assay. Toxicol Appl Pharmacol 308 (Oct 1):77–90; doi: 10.1016/j.taap.2016.07.020 . PMID: 27478144.
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Publication: Manuscripts
/ Topics: Metals
Worth A, Patlewicz G . 2016. Integrated approaches to testing and assessment. Adv Exp Med Biol 856:317-342; doi: 10.1007/978-3-319-33826-2_13 . PMID: 27671729.
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Publication: Book Chapters
/ Topics: Adverse outcome pathways (AOPs) , safety assessment
Patlewicz G , Worth AP, Ball N. 2016. Validation of computational methods. Adv Exp Med Biol 856:165-187; doi: 10.1007/978-3-319-33826-2_6 . PMID: 27671722.
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Publication: Book Chapters
/ Topics: computational toxicology , read-across
Ulrich K . Adversity and risk assessment of respiratory tract findings — A regulatory perspective. Presentation to the 31st Annual Meeting of the British Society of Toxicological Pathology (BSTP) — Association of Inhalation Toxicologists Joint Conference, Alderley Edge, Cheshire, UK, 2016.
Publication: Abstracts and Presentations
/ Topics: regulatory toxicology , risk assessment
Gökbuget N, Kelsh M , Chia V, Advani A, Bassan R, Dombret H, et al. 2016. Blinatumomab vs historical standard therapy of adult relapsed/refractory acute lymphoblastic leukemia. Blood Cancer J 6(9):e473; doi: 10.1038/bcj.2016.84 . PMID: 27662202.
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Publication: Manuscripts
/ Topics: Cancer
Nicholson G, Gandra SR, Halbert RJ, Richhariya A, Nordyke RJ . 2016. Patient-level costs of major cardiovascular conditions: A review of the international literature. Clinicoecon Outcomes Res 21(8):495-506; doi: 10.2147/CEOR.S89331 . PMID: 27703385.
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Publication: Manuscripts
/ Topics: Health Economics and Outcomes Research (HEOR)
Bi P, Yue F, Karki A, Castro B, Wirbisky SE , Wang C, … Kuang, S. 2016. Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. J Exp Med 213(10):2019–2037; doi: 10.1084/jem.20160157 . PMID: 27573812.
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Publication: Manuscripts
/ Topics: Cancer , metabolites
Bi P, Yue F, Sato Y, Wirbisky S , Liu W, Shan T, Wen Y, Zhou D, Freeman J, Kuang S. 2016. Stage-specific effects of notch activation during skeletal myogenesis. Elife 5(Sep 19):e17355; doi: 10.7554/eLife.17355 . PMID: 27644105.
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Publication: Manuscripts
/ Topics: transcriptomics
Rager J, Thompson C , Auerbach S, Fry R. Integrating genomic and epigenomic data into risk assessment applications through dose response modeling: Case study with prenatal arsenic exposure. Environmental Mutagenesis and Genomics Society, Kansas City, KS, September 2016.
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Publication: Abstracts and Presentations
/ Topics: arsenic
Campbell J, Franzen A , Van Landingham C, Lumpkin M, Crowell S, Meredith C, Loccisano A, Gentry R, Clewell H. 2016. Predicting lung dosimetry of inhaled particle-borne benzo(a)pyrene using physiologically based pharmacokinetic modeling. Inhal Toxicol 28(11):520–535; doi: 10.1080/08958378.2016.1214768 . PMID: 27569524.
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Publication: Manuscripts
/ Topics: benzene , PBPK/PBDE , pharmacokinetics
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N , et al. 2016. Integrated decision strategies for skin sensitization hazard. J Appl Toxicol 36(9):1150–1162; doi: 10.1002/jat.3281 . PMID: 26851134.
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Publication: Manuscripts
/ Topics: computational toxicology
Prior H, Bottomley A , Champeroux P, Cordes J, Delphy E, Dybdal N, et al. 2016. Social housing of non-rodents during cardiovascular recording in safety pharmacology and toxicology studies. J Pharmacol Toxicol Methods 81(Sep-Oct):75–87; doi: 10.1016/j.vascn.2016.03.004 . PMID: 27039257.
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Publication: Manuscripts
/ Topics: pharmacology , test methods
Schmitt D, Levy R, Carroll B. 2016. Toxicological evaluation of ß-caryophyllene oil: Subchronic toxicity in rats. Int J Toxicol 35(5):558–567; doi: 10.1177/1091581816655 . PMID: 27358239.
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Publication: Manuscripts
/ Topics: Food science
Wirbisky SE , Sepúlveda MS, Weber GJ, Jannasch AS, Horzmann KA, Freeman JL. 2016. Embryonic atrazine exposure elicits alterations in genes associated with neuroendocrine function in adult male zebrafish. Toxicol Sci 153(1)149–164; doi: 10.1093/toxsci/kfw115 . PMID: 27413107.
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Publication: Manuscripts
/ Topics: atrazine
Lowe KA, Danese MD, Gleeson ML, Langeberg WJ, Kelsh MA . 2016. Racial and ethnic variability in the prevalence and incidence of comorbidities associated with gastric cancer in the United States. J Gastrointest Cancer 47(2):168–181; doi: 10.1007/s12029-016-9809-5 .
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