2013 (7 POSTS)
O’Brien T, Ding H, Suh M , Thompson C , Parsons BL, Harris MA,…, Haws LC , Proctor DM . 2013. Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water. Mutat Res 754(1-2):15-21. doi: 10.1016/j.mrgentox.2013.03.008 . PMID: 23583686.
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Topics: chromium , water
Proctor DM, Suh M, Thompson CM , Harris MA. 2013. Mode of action evaluation for hexavalent chromium-induced lung cancer. Presented at Society of Toxicology 52nd Annual Meeting, March 10-14, San Antonio, TX.
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Topics: Cancer , chromium , mode of action
Thompson CM , Proctor DM , Suh M , Haws LC , Kirman CR, Harris MA. 2013. Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans. Crit Rev Toxicol 43(3):244-274; doi: 10.3109/10408444.2013.768596 . PMID: 23445218.
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Topics: chromium , Exposure Assessment , mode of action
Suh M , Thompson CM , Hixon JG, Harris MA, Kirman CR, Hays S, Haws LC , Proctor DM . Potential involvement of oxidative stress and iron disturbance in the development of oral cavity tumors in rats exposed to hexavalent chromium. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: chromium
Thompson CM , Kirman CR, Proctor DM , Suh M ,Hays SM, Haws LC , Harris MA. A chronic oral reference dose for hexavalent chromium. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: chromium
Kirman CR, Thompson CM , Proctor DM , Suh M , Haws LC , Harris MA, Hays SM. Using PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: chromium , modeling , PBPK/PBDE , pharmacokinetics , toxicokinetics
2012 (11 POSTS)
Kirman CR, Hays SM, Aylward LL, Suh M , Harris MA, Thompson CM , Haws LC , Proctor DM . 2012. Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium. Chem Biol Interact 200(1):45-64; doi: 10.1016/j.cbi.2012.08.016 . PMID: 22981460.
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Topics: chromium , modeling , pharmacokinetics
Proctor DM , Suh M , Aylward LL, Kirman CR, Harris MA, Thompson CM , Gürleyük H, Gerads R, Haws LC , Hays SM. 2012. Hexavalent chromium reduction kinetics in rodent stomach contents. Chemosphere 89(5):487-493; doi: 10.1016/j.chemosphere.2012.04.065 . PMID: 22682893.
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Topics: chromium
Thompson CM , Hixon JG, Proctor DM , Haws LC , Suh M , Urban JD , Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1):68-76; doi: 10.1016/j.yrtph.2012.05.019 . PMID: 22705708.
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Topics: chromium , genotoxicity
Suh M , Ke JG, Hixon G, Proctor DM . Urinary perchlorate, nitrate, thiocyanate and thyroid hormone levels in participants of National Health and Nutrition Examination Survey (NHANES) 2001-2002. Presented at the International Society of Environmental Epidemiology’s 24th Annual Meeting, Columbia, SC, August 2012.
Topics: NHANES
Thompson CM , Fedorov Y, Brown DD, Suh M , Proctor DM , Kuriakose L , Haws L , Harris MA. 2012. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS One 7(8):e42720; doi: 10.1371/journal.pone.0042720 . PMID: 22905163.
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Topics: chromium , genotoxicity
Harris MA, Thompson CM , Wolf JC, Fedorov Y, Hixon JG, Proctor DM, Suh M, Haws LC . Assessment of genotoxic potential of Cr(VI) in the intestine via in vivo intestinal micronucleus assay and in vitro high content analysis in differentiated and undifferentiated caco-2. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Topics: chromium , genotoxicity
Hays SM, Kirman C, Aylward L, Suh M , Proctor D . Gastric reduction of Cr(VI) in mice, rats and humans. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Topics: chromium
Kirman CR, Hays SM, Aylward LL, Suh M , Proctor D . 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Topics: chromium , modeling , pharmacokinetics
Proctor DM, Thompson CM, Suh M, Haws LC , Harris MA. 2012. Mode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
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Topics: carcinogens , chromium , mode of action
O’Brien TJ, Hao D, Suh M, Proctor D, Thompson CM, Harris MA, Parsons BL, Meyers MB. 2012. K-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.
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Topics: chromium , water
Thompson CM , Proctor DM , Suh M , Haws LC , Hebert CD, Mann JF, Shertzer HG, Hixon JG, Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90; doi: 10.1093/toxsci/kfr280 . PMID: 22011396.
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Topics: carcinogens , chromium , mode of action , water
2010 (1 POST)
Gatto NM, Kelsh MA , Mai DH, Suh M , Proctor DM . 2010. Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis. Cancer Epidemiol 34(4):388-399; doi: 10.1016/j.canep.2010.03.013 . PMID: 20430714.
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Topics: Cancer , chromium , Occupational
2009 (1 POST)
Gatto N, Kelsh M , HaMai D, Suh M , Proctor D . A meta-analysis of the relationship between occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract. Society of Toxicology 48th Annual Meeting, Baltimore, MD, March 2009.