Publications

Clewell H, Crump K, Covington T, Gentry R, Yeager J. A risk assessment for inhaled arsenic based on urinary arsenic concentration using a pharmacokinetic model. Poster presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2003.

Clewell HJ, Teeguarden J, McDonald T, Sarangapani R, Lawrence G, Covington T, Gentry R, Shipp A. 2002. Review and evaluation of the potential impact of age and gender-specific pharmacokinetic differences on tissue dosimetry. Crit Rev Toxicol 32(5):329–389.

Gentry PR, Covington TR, Andersen ME, Clewell HJ. 2002. Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration. Regul Toxicol Pharmacol 36:51–68.

Gentry R, Teeguarden J, Sarangapani R, Covington T, Lawrence G, McDonald T, Shipp A, Clewell H. Evaluation of the potential impact of age- and gender-specific pharmacokinetic differences in tissue dosimetry. Poster presented at the Society of Toxicology Annual Meeting, Nashville, TN, March 2002.

Covington TR, Teeguarden J, Sarangapani R, Gentry PR, Clewell HJ. Evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry. Presentation at the Annual Society for Risk Analysis Conference, Seattle, WA, December 2001.

Clewell HJ, Gentry PR, Gearhart JM, Covington TR, Banton MI, Andersen ME. 2001. Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone. Toxicol Sci 63:160–172.

Shipp AM, Gentry PR, Lawrence G, Van Landingham C, Covington T, Clewell HJ, Gribben K, Crump K. 2000. Determination of a site-specific reference dose for methylmercury for fish-eating populations. Toxicol Ind Health 16(9-10):335–438.

Andersen ME, Sarangapani R, Gentry PR, Clewell HJ, Covington TR, Frederick CB. 2000. Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: An example with acrylic acid. Toxicol Sci 57:312–325.

Clewell HJ III, Gentry PR, Allen BC, Covington TR, Gearhart JM. 2000. Development of a physiologically-based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment. Environ Health Perspect 108(Suppl 2):283–305.

Gentry R, Clewell H, Covington T, Wilson J. Investigation of the impact of Benchmark and PBPK modeling on the derivation of MRLs. Poster presented at the Society of Toxicology Annual Meeting, Philadelphia, PA, March 2000.

Clewell HJ, Gentry PR, Gearhart JM, Born SL, Lehman-McKeeman LD, Covington TR. Development of a physiologically-based pharmacokinetic (PB-PK) model and human health risk assessment for coumarin.  Poster presented at the Society of Toxicology Annual Meeting, Philadelphia, PA, March 2000.

Clewell HJ, Gearhart JM, Gentry PR, Covington TR, Van Landingham CB, Crump KS, and Shipp AM. 1999. Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics. Risk Anal 19:541–552.

Gentry R, Clewell H, Gearhart J, Covington T, Andersen M. Development of a physiologically-based pharmacokinetic (PB-PK) model for isopropanol and acetone. Poster presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 1999.

Van Landingham CB, Covington TR, Gearhart JM, Clewell HJ. Evaluation of the uncertainty in the RfD for methylmercury due to interindividual variability in pharmacokinetics. Poster presented at the Society of Toxicology Annual Meeting, Seattle, WA, March 1998.

Clewell HJ, Covington TR, Gearhart JM. Application of a physiologically based pharmacokinetic (PBPK) model for methylmercury (MeHg) in a dose reconstruction of the Iraqi accidental exposures. Poster presented at the Society of Toxicology Annual Meeting, Seattle, WA, March 1998.

Covington TR, Barton HA, Clewell HJ III. Evaluating pharmacokinetics and pharmacodynamics for noncancer effects from trichloroethylene (TCE). Poster presented at the Society of Toxicology Annual Meeting, Cincinnati, OH, March 1997.

Hochberg F, Miller G, Valenzuela R, McNelis S, Crump KS, Covington T, Valdivia G, Hochberg B, Trustman JW. 1996. Late motor deficits of Chilean manganese miners: A blinded control study. Neurology 47:788–795.

Allen BC, Covington TR, Clewell HJ III. 1996. Investigation of the impact of pharmacokinetic variability and uncertainty on risks predicted with a pharmacokinetic model for chloroform. Toxicology 111:289–303.

Covington TR, Clewell HJ III, Gearhart JM, Andersen ME. Developing physiologically-based pharmacokinetic (PB-PK) models for manganese and iron. Poster presented at the Society of Toxicology Annual Meeting, Anaheim, CA, March 1996.

Covington TR, Gearhart JM, Clewell HJ. A physiologically based pharmacokinetic (PBPK) model for 133Xe and 222Rn in the human. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 1995.