Publication Topic

Greene N, Gosink M. 2013. Computational toxicology experience and applications for risk assessment in the pharmaceutical industry. Chapter 10 in: Fowler BA (ed), Computational Toxicology: Methods and Applications. Elsevier-Academic Press, pp. 171-193; doi: 10.1016/B978-0-12-396461-8.00012-9.

Meddings J, Reichert H, Rogers MAM, Iwashyna TJ, McMahon L. Hospitals reporting better adherence to perioperative blood clot prophylaxis do not report lower rates of hospital-acquired post-operative blood clots. Presented at the 2012 Society of General Internal Medicine Annual Meeting, Orlando, FL, May 9-12, 2012.

Wang X, Greene N. 2012. Comparing measures of promiscuity and exploring their relationship to toxicity. Molec Inform 3(2):145-159; doi: 10.1002/minf.201100148. PMID: 27476959. Awarded Best Paper of 2012 by the editors of Molecular Informatics.

Urban JD, Clarke WP, von Zastrow M, Kobilka B, Nichols DE, Weinstein H, Javitch JA, Roth BL, et al. 2007. Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Therap 320(1):1-13; doi: 10.1124/jpet.106.104463. PMID: 16803859.

Urban JD, Thornley K, Wightman RW, Mailman RB. Pharmacological characterization of the N27-D2L cell line: Assessment as a viable cell model for investigating D2L receptor dopaminergic-coupled functions. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.

Leighton JK, Brown P, Ellis A, Harlow P, Harrouk W, Pine PS, Robison T, Rosario L, Thompson K. 2006. Workgroup Report: Review of genomic data based on experience with mock submissions: View of the CDER Pharmacology Toxicology Nonclinical Pharmacogenomics Subcommittee. Environ Health Perspect 114:573-578; doi: 10.1289/ehp.8318. PMID: 16581548.

Urban JD, Mailman RB. Functional selectivity as a mechanism of action for newer atypical antipsychotic drugs. Presented at Merck, West Point, PA, 2005.

Urban JD, Mailman RB. Characterization of the N27 dopaminergic cell line as a model for elucidating the actions of functionally selective dopaminergic ligands. 35th Annual Neuroscience Meeting, Washington, DC, November 2005.

Urban JD, Gay EA, Mailman RB. Functional selectivity as a mechanism of action of newer atypical antipsychotic drugs. 34th Annual Neuroscience Meeting, San Diego, CA, October 2004.

Thompson CM, Wojno H, Greiner E, May EL, Rice KC, Selley DE. 2004. Activation of G-proteins by morphine and codeine congeners: Insights to the relevance of O- and N-demethylated metabolites at μ- and δ-opioid receptors. J Pharmacol Exper Therapeut 308(2):547–554; doi: 10.1124/jpet.103.058602. PMID: 14600248.

Booth RG, Moniri NH, Bakker RA, Choksi NY, Nix WB, Timmerman H, Leurs R. 2002. A novel phenylaminotetralin radioligand reveals a sub-population of histamine H1 receptors. J Pharmacol Exper Therapeut 302(1):328–336; doi: 10.1124/jpet.302.1.328. PMID: 12065734.

Booth RB, Brown RL, Bucholtz ED, Choksi NY, Owens CE, Wyrick S.D. Phenylaminotetralins: A new class of histamine H1-type ligands that affect catecholamine synthesis and release in vitro and in vivo. Society for Neuroscience Abstracts, 24:1838, 1998

Kawashima H, Kusunose E, Thompson CM, Strobel HW. 1997. Protein expression, characterization, and regulation of CYP4F4 and CYP4F5 cloned from rat brain. Arch Biochem Biophys 347(1):148–154; doi: 10.1006/abbi.1997.0342. PMID: 9344476.

Choksi NY, Wyrick SD, Booth RG. Phenylaminotetralins modulate dopamine synthesis in rat nucleus accumbens in vivo by a presynaptic H1-type receptor. Poster presented at Society for Neuroscience Annual Meeting, 1997.

Grover GJ, Dzwonczyk S, Monticello TM. 1996. Comparative cardioprotective effects of cromakalin and diltiazem in ischemic hypertrophied and non-hypertrophied rat hearts. Am J Physiol 270(1 Pt 2):H174-H182; doi: 10.1152/ajpheart.1996.270.1.H174. PMID: 8769749.

Liu RM, Hu H, Robison TW, Forman HJ. 1996. Increased γ-glutamylcysteine synthetase and γ-glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity. Amer J Resp Cell Mol Biol14(2):192-197; doi: 10.1165/ajrcmb.14.2.8630270. PMID: 8630270.