Publication Topic

Rooney JP, Choksi NY, Ceger P, Daniel AB, Truax J, Allen D, Kleinstreuer N 2021. Analysis of variability in in vivo rabbit skin irritation assay results. Regul Toxicol Pharmacol 122(June):104920; doi: 10.1016/j.yrtph.2021.104920.

Choksi NY, Daniel AB, Allen DG, Clippinger AJ, Kleinstreuer NC. 2021. Prospective and retrospective evaluation of the eye irritation potential of agrochemical formulations. Research Triangle Park, NC: National Toxicology Program. NICEATM Report 01.

O’Neil HC, Vincent MJ, Han AA, Brown SE, Hazell AM, Krieder ML, Madl AM. Hazard and risk banding framework for prioritization and bridging of e-liquids for toxicity testing. Poster presented at Society of Toxicology Annual Meeting, virtual event, March 2021.

Rooney JP, Choksi N, Ceger P, Daniel AB, Truax J, Allen DG, Kleinstreuer NC. Variability in the rabbit skin irritation assay. Poster presented at Society of Toxicology 60th Annual Meeting, Virtual, March 2021.

Chang Y, Huynh CTT, Bastin KM, Rivera BN, Siddens LK, Tilton SC. 2020. Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures. Toxicol in Vitro 69:104991, doi: 10.1016/j.tiv.2020.104991.

Parker J, Boles C, Leleck O, Buerger AN, Egnot N, Sunderman A, et al. 2020. Advancing toward normal operations for arenas and stadiums. Toxicol Ind Health 36(9):718–727.

Zorn KM, Foil DH, Russo DP, Clark AM, Hillwalker W, Feifarek D, Jones F, Klaren W, Brinkman A, Ekins S. Generation of machine-learning models to anticipate endocrine disruption. Society of Toxicology 59th Annual Meeting, virtual, 2020.

Brinkman AM, Klaren WD, Feifarek DJ, Hillwalker W, Jones F, Zorn KM, Ekins S. Use of a weighted scheme for the interpretation and contextualization of in vitro and in silico-derived estrogenic endpoints. Society of Toxicology 59th Annual Meeting, virtual, 2020.

Zorn KM, Foil DH, Lane TR, Russo DP, Hillwalker W, Feifarek DJ, Jones F, Klaren WD, Brinkman AM, Ekins S. 2020. Machine learning models for estrogen receptor bioactivity and endocrine disruption prediction. Environ Sci Technol 54(19):12202–12213; doi: 10.1021/acs.est.0c03982. PMID: 32857505.

Zorn KM, Foil DH, Lane TR, Hillwalker W, Feifarek DJ, Jones F, Klaren WD, Brinkman AM, Ekins S. 2020. Comparing machine learning models for aromatase (P450 19A1). Environ Sci Technol 54(23):15546–15555; doi: 10.1021/acs.est.0c05771. PMID: 33207874.

Heintz MM, McRee, R, Kumar, R, Baldwin, WS. 2020. Gender differences in diet-induced steatotic disease in Cyp2b-null mice. PLoS ONE 15(3):e0229896; doi: 10.1371/journal.pone.0229896.

Choksi N, Clippinger AJ, Gehen S, Corvaro M, Kolle SN, Bentley K, et al. Developing a defined approach for eye irritation testing. Poster presented at Society of Toxicology 59th Annual Meeting, Virtual, March 2020.

Choksi N, Lebrun S, Nguyen M, Daniel A, DeGeorge G, Willoughby J, et al. 2020. Validation of the OptiSafe Eye Irritation Test. Cutan Ocul Toxicol 39(3):180–192; doi: 10.1080/15569527.2020.1787431.

Rivera BN, Mullen K, Tidwell L, Ivanek R, Ainsworth D, Tilton S, Anderson K. Time-integrated exposures to identify chemical profiles between health and dysphagic foals. New Frontiers in Dynamic Toxicology, Society of Toxicology Virtual Annual Meeting, March 2020.

Heintz MM, Olack EM, Baldwin WS. Human CYP2B6 is an anti-obesity enzyme that produces active α-linolenic acid metabolites. Society of Toxicology 59th Annual Meeting, Virtual, March 2020.

Heintz MM, McRee R, Kumar R, Baldwin WS. Gender differences in diet-induced nonalcoholic steatohepatitis (NASH) in Cyp2b-null mice. Society of Toxicology 59th Annual Meeting, Virtual, March 2020.

Rogers EN, Mihalchik AL, Gad, SC. Comparison and analysis of discrepancies among commonly used Cramer decision tree methods in Toxtree software.  Abstract no. 1517. Society of Toxicology 59th Annual Meeting, Virtual, 2020.

Brown L, Lynch M, Belova A, Klein R, Chiger A. 2020. Developing a health impact model for adult lead exposure and cardiovascular disease mortality. Environ Health Persp 128:9, https://doi.org/10.1289/EHP6552.

Liu S, Refaei M, Liu S, Decker A, Hinerman JM, Herr AB, Howell M, Musier-Forsyth K, Tsang P. 2020. Hairpin RNA-induced conformational change of a eukaryotic-specific lysyl-tRNA synthetase extension and role of adjacent anticodon-binding domain. J Biol Chem 295(34):12071–12085.

Mease K. Managing immunogenicity in the absence of an ADA assay is no monkey business (case study). Presentation at 25^th annual Charles River Biotech Symposium, Carlsbad, CA, September 2019.