2022 (53 POSTS)

Lynch HN, Lauer DJ, Thompson WJ, Leleck O, Freid RD, Collins J, Chen K, et al. 2022. Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc. Front Public Health 10:989111; doi: 10.3389/fpubh.2022.989111.

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Campion SN, Potter DM, Bowman CJ, Catlin NR, Davis S, Millard C, Nowland WS, Stethem CM, Hollingshead BD, Radi ZA, Coder PS, Cappon GD. 2022. Lack of effects on bone growth and development following administration of tofacitinib, a JAK inhibitor, to juvenile rats and evaluation of the association between offspring growth and femur length. Reprod Toxicol 113:35–41, DOI: 10.1016/j.reprotox.2022.08.002, article online

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House JS, Grimm FA, Klaren WD, Dalzell A, Kuchi S, Zhang S, Lenz K, Boogaard PJ, Ketelsegers HB, Gant TW, Wright FA, Rusyn I. 2022. Grouping of UVCB substances with dose-response transcriptomics data from human cell-based assays. ALTEX 39(3):388-404, PMID: 35288757

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Lea IA, Pham LL, Antonijevic T, Thompson C, Borghoff SJ. 2022. Assessment of the applicability of the threshold of toxicological concern for per- and polyfluoroalkyl substances. Regul Toxicol Pharmacol 133:105190, open access.

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Buetow BS, Cappon GD, Aschenbrenner L/M, Updyke L, Torti VR, Evans M, et al. 2022. Regulatory experience assessing the carcinogenic potential of a monoclonal antibody inhibiting PCSK9, Bococizumab, including a 2-year carcinogenicity study in rats. Int J Toxicol 5:389–401, DOI: 10.1177/10915818221106397, online article.

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Verwiel A, Racz L, Mittal L, Rish W. 2022. CDC’s national report on human exposure to environmental chemicals. SETAC Globe 23(6).

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Martyniuk CJ, Buerger AN, Vespalcova H, Rudzanova B, Sohan SR, Hanlon AT, et al. 2022. Sex-dependent host-microbiome dynamics in zebrafish: Implications for toxicology and gastrointestinal physiology. Comp Biochem Physiol Part D Genomics Proteomics 42:100993; DOI: 10.1016/j.cbd.2022.100993.

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Campion SN, Nowland WS, Gropp K, Liu C-H, Ritenour HN, Syed J, Catlin NR, Stethem CM, Coskran TM, Cappon GD. 2022. Assessment of postnatal femur development in Wistar Han rats. Bone Rev 80:319–325, doi: 10.1016/j.reprotox.2021.05.007, open access online.

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Catlin NR, Bowman CJ, Campion SN, Lewis EM, Nowland WS, Stethem CM, Cappon GD. 2022. The postnatal resolution of developmental toxicity induced by pharmacological DGAT2 inhibition during gestation in rats. J Toxicol Sci 189:225–236, DOI: 10.1093/toxsci/kfac077, article online.

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Buerger AN, Parente CE, Harris JP, Watts EG, Wormington AM, Bisesi JH. 2022. Impacts of diethylhexyl phthalate and overfeeding on physical fitness and lipid mobilization in Danio rerio (zebrafish). Chemosphere 295:133703.

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Racz, L. PFAS: How did we get here and where are we going? Keynote address at Alliance of Hazardous Materials Professionals national meeting, Las Vegas, NV, Mar 2022.

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Rooney J, Abedini J, Bell S, Chang X, Cook B, Ceger P, Choksi N, et al. Building confidence in alternative methods through ICE. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Proctor DM, Antonijevic T. Refined health risk assessment for residential exposures to manganese in EAF steel slag. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Klaren WD, Hoberman AM, Hauswirth JW. Reproduction and developmental toxicological evaluation of piperonyl butoxide (PBO). Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Rogers JM, Heintz MM, Thompson CM, Haws LC. Development of a putative adverse outcome pathway for neonatal mortality in rodents: Implications for human health risk assessments of PFAS. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Thompson CM, Chappell GA, Mittal L, Gorman B, Proctor DM, Haws LC, Harris MA. Use of targeted mode-of-action research to inform human health risk assessment of hexavalent chromium. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Chappell G, Wolf JC, Harris MA, Thompson CM. Variation in transcriptomic responses in the crypt and villus of mouse small intestine following oral exposure to hexavalent chromium. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Heintz MM, Chappell GA, Thompson CM, Wolf JC, Rogers JM, Haws LC. HFPO-DA (GenX) transcriptomic responses in pregnant and non-pregnant rat livers: Analyses to inform the role of maternal effects on neonatal toxicity. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Mihalchik A, Wood M. Considerations for standardization and derivation of pediatric and neonatal tolerable exposure limits for extractable and leachable compounds from medical devices. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

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Bates C, Russell A, Dotson GS, Vincent M, Lotter J, Maier MA. Establishing OELs for sensory irritants with limited data using predictive and in silico models. Poster presentation P126 at the Society of Toxicology (SOT) Annual Meeting & ToxExpo, San Diego, CA. Toxicologist Late-Breaking Supp. 168(1):17. Abstract 5023. March 2022.

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