David RM, Clewell HJ, Gentry PR, Covington TR , Morgott DA, Marino DJ. 2006. Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations. Regul Toxicol Pharmacol 45(1):55–65; doi: 10.1016/j.yrtph.2005.12.003 .
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Publication: Manuscripts
/ Topics: Cancer , PBPK/PBDE
Marino DJ, Clewell HJ, Gentry PR, Covington TR , Hack CE, David RM, Morgott DA. 2006. Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose-response modeling in mice. Regul Toxicol Pharmacol 45(1):44–54; doi: 10.1016/j.yrtph.2005.12.007 .
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Publication: Manuscripts
/ Topics: Bayesian modeling , Cancer , dose-response , modeling , PBPK/PBDE , risk assessment
Degregorio MW, Dingley KH , Wurz GT, Ubick E, Turteltaub KW. 2006. Accelerator mass spectrometry allows for cellular quantification of doxorubicin at femtomolar concentrations. Cancer Chemother Pharmacol 57(3):335-342; doi: 10.1007/s00280-005-0060-1 . PMID: 16047147.
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Publication: Manuscripts
/ Topics: Cancer , spectrometry
Tompkins EM, Farmer PB, Lamb JH, Jukes R, Dingley K , Ubick E, et al. 2006. A novel 14C-postlabeling assay using accelerator mass spectrometry for the detection of O6-methyldeoxy-guanosine adducts. Rapid Commun Mass Spectrom 20(5):883–891; doi: 10.1002/rcm.2370 . PMID: 16470516.
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Publication: Manuscripts
/ Topics: spectrometry
Borowsky AD, Dingley KH , Ubick E, Turteltaub KW, Cardiff RD, Devere-White R. 2006. Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model. Neoplasia 8(9):708–715; doi: 10.1593/neo.06373 . PMID: 16984728.
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Publication: Manuscripts
Malfatti MA, Dingley KH , Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573 . PMID: 17079477.
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Publication: Manuscripts
/ Topics: Cancer , carcinogens
Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM , Lindstrom AB, Strynar MJ. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicol Sci 90(2):510–518; doi: 10.1093/toxsci/kfj105 .
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Publication: Manuscripts
/ Topics: PFAS
Rogers JM . 2006. Casting a broad network: Fishing for mechanisms of retinoid teratogenicity. Toxicological highlight. Toxicol Sci 94(1):1–2; doi: 10.1093/toxsci/kfl104 .
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Publication: Manuscripts
/ Topics: Toxicology
Staskal DF , Hakk H, Bauer D, Diliberto JJ, Birnbam LS. 2006. Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Toxicol Sci 94(1):28-37; doi: 10.1093/toxsci/kfl091 .
View Abstract
Publication: Manuscripts
/ Topics: flame retardants , PBPK/PBDE , toxicokinetics
Haws L . The use of toxic equivalency factors to assess potential human health risks posed by dioxin-like compounds: Keeping up with the science. Presented at Michigan State University, Toxicology Program Seminar Series, September,, 2006.
Publication: Abstracts and Presentations
/ Topics: dioxin , risk assessment
Wheeler MW , Park RM, Bailer AJ. 2006. Comparing median lethal concentration values using confidence interval overlap or ratio tests. Environ Toxicol Chem 25(5):1441-4; doi: 10.1897/05-320r.1. PMID: 16704080.
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Publication: Manuscripts
/ Topics: risk analysis , risk assessment
Buffler PA, Kelsh MA , Lau EC, Edinboro CH, Barnard JC, Rutherford GW, et al. 2006. Thyroid function and perchlorate in drinking water: An evaluation among California newborns, 1998. Environ Health Persp 114(5):798–804; doi: 10.1289/ehp.8176 . PMID: 16675440.
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Publication: Manuscripts
/ Topics: community health , risk assessment , water
Van den Berg M, Birnbaum L, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws LC , Rose M, Safe S, Schrenk D, Tohyama C, Tritscher A, Tuomisto J, Tysklind M, Walke Nr, Peterson RE. 2006. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93(2):223-241; doi: 10.1093/toxsci/kfl055 .
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Publication: Manuscripts
/ Topics: dioxin
Haws LC, Scott PK, Unice KM, Gough M, Harris MA, Staskal DF , Paustenbach DJ, Pavuk M. Are dioxin body burdens surrogates for other risk factors in associations between dioxin and diabetes? Dioxin 2006 , Oslo, Norway, August 2006.
Publication: Abstracts and Presentations
/ Topics: diabetes , dioxin
Leighton JK, Brown P, Ellis A, Harlow P, Harrouk W, Pine PS, Robison T , Rosario L, Thompson K. 2006. Workgroup Report: Review of genomic data based on experience with mock submissions: View of the CDER Pharmacology Toxicology Nonclinical Pharmacogenomics Subcommittee. Environ Health Perspect 114:573-578; doi: 10.1289/ehp.8318 .
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Publication: Manuscripts
Jackson MA, Lea I , Rashid A, Peddada SD, Dunnick JK. 2006. Genetic alterations in cancer knowledge system: Analysis of gene mutations in mouse and human liver and lung tumors. Toxicol Sci 90(2):400–418; doi: 10.1093/toxsci/kfj101 .
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Publication: Manuscripts
/ Topics: Cancer
Hamernik K, Eskes C, Merrill J, Choksi N , Allen D, Truax J, et al. 2006. ICCVAM-NICEATM-ECVAM symposium on mechanisms of chemically-induced ocular injury and recovery: Current understanding and knowledge gaps. ALTEX 23 Suppl:322–324 .
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Publication: Manuscripts
/ Topics: Toxicology
Haws LC , DeVito MJ, Birnbaum LS, Walker NJ, Scott PK, Unice KM, Harris MA , Farland WH, Finley BL , Staskal DF . An alternative method for establishing TEFs for dioxin-like compounds. Part 2. Development of an approach to quantitatively weight the underlying potency data. Dioxin 2006 , Oslo, Norway, 2006.
Publication: Abstracts and Presentations
/ Topics: dioxin , Environmental Science , Exposure Assessment
Covington TR , Gentry P, Van Landingham CB, Clewell HJ. Issues in using Markov Chain Monte Carlo analysis to calibrate a PBPK model for use in risk assessment: Case studies with dichloromethane and perchloroethylene. Poster presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 2006.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Tice RR, Allen DG, Choksi NY , Truax JF, Stokes WS. Evaluation of the relationship between in vivo rabbit eye test scores and their reversibility. Poster presented at Society of Toxicology 45th Annual Meeting, San Diego, CA, March 2006.
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