Yong M, Kuehn C, Kelsh M , Mitchell M , et al. Associations between platelet count and survival and disease progression in thrombocytopenic patients with myelodysplastic syndromes. Presented at the American Society of Hematology, Orlando, FL, December 2010.
Publication: Abstracts and Presentations
/ Topics: Epidemiology
Daston GP, Chapin R, Scialli AR, Piersma AH, Carney EW, Rogers JM , Friedman JM. 2010. A different approach to validating screening assays for developmental toxicity. Birth Defects Res B 89(6):526–530. doi: 10.1002/bdrb.20276 . PMID: 21086491.
View Abstract
Publication: Manuscripts
/ Topics: reproductive toxicology , test methods
Robison TW . Genotoxic impurity guidance – Current experiences, FDA perspective. USP Annual Meeting, New Orleans, LA, December 2010.
Publication: Abstracts and Presentations
/ Topics: genotoxicity
Tachovsky JA, Haws L . Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI. Presented at the Society for Risk Analysis Annual Meeting, Salt Lake City, UT, December 2010.
Publication: Abstracts and Presentations
/ Topics: dioxin
Mueser TC, Hinerman JM , Devos JM, Boyer RA, Williams KJ. 2010. Structural analysis of bacteriophage T4 DNA replication: Review in the Virology Journal series on bacteriophage T4 and its relatives. Virol J 7(Dec 3):359; doi: 10.1186/1743-422X-7-359 . PMID: 21129204.
View Abstract
Publication: Manuscripts
/ Topics: modeling
Harris M, Tachovsky JA, Staskal-Wikoff D , Aylward L, Burkhalter B, Simon T, Haws L . Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, San Antonio, TX, September 2010.
Publication: Abstracts and Presentations
/ Topics: dioxin
Johns DO, Owens EO, Thompson CM , Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.
View Abstract
Publication: Book Chapters
/ Topics: modeling , PBPK/PBDE
Sterner TR, Ruark CD, Covington TR , Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Publication: Abstracts and Presentations
/ Topics: modeling , PBPK/PBDE
Makley M, Ruark C, Covington T , Robinson P, Gearhart J. Route of entry model for predicting chemical warfare agent miosis. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Publication: Abstracts and Presentations
/ Topics: modeling
Covington T , Robinson P, Gearhart J. Exploring issues in simulating dermal exposure using a physiologically-based pharmacokinetic-pharmacodynamic (PBPK-PD) model for VX. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.
Publication: Abstracts and Presentations
/ Topics: PBPK/PBDE , pharmacokinetics
Kreider ML, Unice KM, Panko JM , Burns AM , Paustenbach DJ, Booher LE, Gelatt RH, Gaffney SH. 2010. Benzene exposure in refinery workers: ExxonMobil Joliet, Illinois, USA (1977-2006). Toxicol Ind Health 26(10):671-90; doi: 10.1177/0748233710378115 . PMID: 20643709.
View Abstract
Publication: Manuscripts
/ Topics: benzene , Exposure Assessment , Occupational , Refineries
Hess G, Nordyke RJ , Hill J, Hulnick S. 2010. Effect of reimbursement changes on erythropoiesis-stimulating agent utilization and transfusions. Am J Hematol 85(11):838-43; doi: 10.1002/ajh.21837 . PMID: 20976794.
View Abstract
Publication: Manuscripts
/ Topics: Cancer , Health Economics and Outcomes Research (HEOR)
Cain WS, Dourson ML, Kohrman-Vincent MJ , Allen BC. 2010. Human chemosensory perception of methyl isothiocyanate: Odor and chemesthesis. Regul Toxicol Pharmacol 58(2):173–180; doi: 10.1016/j.yrtph.2010.06.018 . PMID: 20633589.
View Abstract
Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , modeling
Harris M, Tachovsky JA, Staskal-Wikoff D , Simon T, Burkhalter B, Urban J , Haws L . 2010. Assessment of the impact of various soil cleanup levels on serum concentrations of dioxin-like compounds in humans. Presented at Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, March 2010.
Publication: Abstracts and Presentations
/ Topics: dioxin
Birnbaum LS, Staskal-Wikoff D . 2010. 5th International PCB Workshop–Summary and implications. Environ Int 36(8):814-818; doi: 10.1016/j.envint.2010.06.011 .
View Abstract
Publication: Manuscripts
/ Topics: PCBs , risk assessment
Chen F, Smith R, Gu YZ, Collins ND , Nioi P. 2010. Toxicoepigenetic alteration of the Kidney Injury Molecule 1 gene in gentamicin-exposed rat kidney. Toxicol Sci 117(2):375–380; doi: 10.1093/toxsci/kfq202 . PMID: 20660082.
View Abstract
Publication: Manuscripts
/ Topics: genotoxicity
Chen F, Smith R, Gu YZ, Collins ND , Nioi P. 2010. Toxicoepigenetic alteration of the Kidney Injury Molecule 1 gene in gentamicin-exposed rat kidney. Toxicol Sci 117(2):375–380; doi: 10.1093/toxsci/kfq202 . PMID: 20660082.
View Abstract
Publication: Manuscripts
/ Topics: biomarkers
Poulet FM, Penraat K, Collins N , Evans E, Thackaberry E, Manfra D, et al. 2010. Drug-induced hemolytic anemia and thrombocytopenia associated with alterations of cell membrane lipids and acanthocyte formation. Toxicol Pathol 38(6):907–922; doi: 10.1177/0192623310378865 . PMID: 20805317.
View Abstract
Publication: Manuscripts
/ Topics: drug interactions
Robison TW . Dealing with positive in vitro mammalian cell genotoxicity assays. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.
Publication: Abstracts and Presentations
/ Topics: genotoxicity
Robison TW . Dealing with genotoxic impurities from a regulatory perspective. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.