Martini C, Rashid A, Paleja A, Lea I , Fostel JM. Chemical Effects in Biological Systems (CEBS) database: Treatment-related findings. Presented at the 56th Annual Meeting of Society of Toxicology, Baltimore, MD, March 2017. Abstract 1381-P119.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Sheridan E, Martini C, Shaw M, Shockley K, Brix A, Rashid A, Lea I , Fostel J. Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions. Presented at the 36th Annual Symposium of Society for Toxicologic Pathology, Montreal, Quebec, Canada, June 2017. Poster P035.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Jackson M, Yang L, Yauk CL, Lea I , Kuo B, Williams A, Rashid A, Fostel J. The TGx-28.65 biomarker — A web-based application using transcriptomics to identify DNA damage-inducing chemicals. Presented at the 48th Annual Meeting of Environmental Mutagenesis and Genomics Society, Raleigh, NC, September 2017. Abstract 1224.
Publication: Abstracts and Presentations
/ Topics: Toxicology
Kirman CR, Suh M, Proctor DM , Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325:9-17.
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Publication: Manuscripts
/ Topics: Cr(VI) MOA Study , Hexavalent Chromium , Toxicology
Wikoff DS, Rager J, Harvey S, Haws L, Chappell G, Borghoff S . 2017. Framework for quantitative consideration of study quality and relevance in the systematic evaluation of mechanistic data per the Ten Key Characteristics of Carcinogens. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.
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Publication: Abstracts and Presentations
/ Topics: Toxicology
Jackson MA, Yang L, Lea I , Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535.
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Publication: Manuscripts
/ Topics: Toxicology
Mease K, Kimzey A, Lansita J. 2017. Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design. Curr Opin Toxicol (4:1–15).
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Publication: Manuscripts
Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N , et al. 2017. Multivariate models for prediction of human skin sensitization hazard. J Appl Toxicol 37:347–360, DOI: 10.1002/jat.3366.
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Publication: Manuscripts
/ Topics: Toxicology
Lea IA , Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971.
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Publication: Manuscripts
/ Topics: Toxicology
Williams BH, Monnot AD, Patton A, Finley BL . Proposed chronic oral reference doses for thallium. Late-breaking poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
Publication: Abstracts and Presentations
/ Topics: Metals , Toxicology
Kovochich M, Fung ES, Donovan EP, Unice KM, Paustenbach DJ, Finley BL . Characterization of wear debris from metal-on-metal hip implants during normal wear versus edge loading conditions. Abstract #2143. Poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
Publication: Abstracts and Presentations
/ Topics: Metals , Toxicology
Fung ES, Monnot AD, Tvermoes BE, Unice KM, Kovochich M, Galbraith DA, Finley BL , Paustenbach DJ. Characteristics of cobalt related cardiomyopathy in metal hip implant patients. Abstract #2142. Poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
Publication: Abstracts and Presentations
/ Topics: cobalt , Toxicology
Finley BL , Scott PK, Burns AM, Marsh GM. Does PCB exposure cause non-Hodgkins lymphoma? A weight of evidence evaluation. Late-breaking poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
Publication: Abstracts and Presentations
/ Topics: Cancer , Exposure Assessment , PCBs
Finley BL , Glynn ME, Cyrs WD, Beckett EW, Gaffney SH, Monnot AD, Abelmann A, Parker A, Maier MA. Derivation of an occupational exposure limit for diacetyl: A preliminary analysis. Late-breaking poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
Publication: Abstracts and Presentations
/ Topics: diacetyl , Exposure Assessment , Occupational , Toxicology
Finley BL , Donovan ED, Kovochich M, Paustenbach DJ, Urban AM. Perineal use of cosmetic talc as a risk factor for ovarian cancer: A weight-of-evidence evaluation. Abstract #1288. Poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
Publication: Abstracts and Presentations
/ Topics: Cancer , risk assessment , talc , Toxicology
Benson SM, Marsh GM, Finley BL . Cosmetic talc as a risk factor for mesothelioma: A weight-of-evidence evaluation. Abstract #1290. Poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.
/ Topics: Exposure Assessment , talc , Toxicology
Doepker D , Tyndall K, Lane R, Wikoff D, Thompson C, Harvey S, Schmitt D . 2017. A proposed ADI for nitrate. Poster presented at Society of Toxicology Annual Meeting, March 16, Baltimore, MD.
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Publication: Abstracts and Presentations
Borghoff SJ, Ring C, Banton MI, Leavens TL. 2017. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to ?2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology Annual Meeting, March 16, Baltimore, MD.
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Publication: Abstracts and Presentations
Thompson C, Rager J, Suh M, Proctor D, Haws L, Harris M . 2017. Mechanistic support for nonlinear risk assessment of rat oral cavity tumors induced by exposure to Cr(VI) in drinking water. Poster presented at Society of Toxicology Annual Meeting. March 15, Baltimore, MD.
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Publication: Abstracts and Presentations
Chappell G, Welsh B, Harvey S, Harris M, Wikoff D . 2017. Validation and application of a text mining tool in the identification and categorization of mechanistic data: A case study in improving problem formulation of carcinogenicity assessments. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.
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