2025 (29 POSTS)
Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M, Gray F, Jensen K, Dahlgren M, Pelletier R, Dingley K, et al. 2025. In silico enabled discovery of KAI-11101, a preclinical DLK inhibitor for the treatment of neurodegenerative disease and neuronal injury. J Med Chem 68(3):2720-2741; doi: 10.1021/acs.jmedchem.4c02074 . PMID: 39670820.
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Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 . PMID: 40084233.
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Topics: Cancer , carcinogens , MTBE , risk assessment
Rogers JM, Buerger AN , Heintz MM , Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 . PMID: 40123861.
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Topics: phthalates
Lea IA , Buerger AN , Feifarek D, Mihalchik A, Heintz MM, Haws LC , Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220 . PMID: 40092461. Corrigendum 8:100233; doi: 10.1016/j.crtox.2025.100233 ; PMID 40529321.
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Topics: phthalates
Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE . 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030 . PMID: 39873747.
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Topics: Ecology , risk assessment , Toxicology
Schaefer HR , Vincent MJ , Burns CJ, Lange SS. 2025. Increasing the utility of epidemiologic studies as key evidence in chemical risk assessment. Toxicol Sci 203(2):166-170; doi: 10.1093/toxsci/kfae134 . PMID: 39657235.
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Topics: Epidemiology , risk assessment
Zilber D, Messier KP, House J, Parham F, Auerbach SS, Wheeler MW . 2025. Bayesian gene set benchmark dose estimation for “omic” responses. Bioinformatics 41(1):btaf008; doi: 10.1093/bioinformatics/btaf008 . PMCID: PMC11783320.
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Topics: benchmark dose estimation (BMD) , Toxicology , transcriptomics
Rana Z, Frankenfeld CL , Kennedy E, Bertoldi J, de Jonge E, Cheskin L. 2025. Food sources of energy and nutrients among US college students: The Health Starts Here cohort study. J Am Coll Health 73(1):301-310; doi: 10.1080/07448481.2023.2220397 . PMID: 37290009.
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Topics: Epidemiology , Food science
Lipworth L, Panko JM , Allen BC, Mumma MT, Jiang X , Vincent MJ , Bare JL , Antonijevic T, Vivanco SN , Marano DE, Suh M , Cohen S, Mittal L , Proctor DM . 2025. Lung cancer mortality among aircraft manufacturing workers with long-term, low-level, hexavalent chromium exposure. J Occup Environ Hyg 22(3):214-227 ; doi: 10.1080/15459624.2024.2439817 . PMID: 39773194.
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Topics: Cancer , chromium , Exposure Assessment , Hexavalent Chromium , Occupational
2024 (66 POSTS)
Kim A, Cong Z, Jazieh A-R, Church TR, Reichert H , Nicholson G, Fryzek J, Cohen SS. 2024. Estimating the incremental population health impact of a multi-cancer early detection (MCED) test to complement existing screening among elevated risk populations with multiple cancer risk factors: A mathematical modeling study. BMC Health Serv Res 24(1):1584; doi: 10.1186/s12913-024-12037-1 . PMID: 39695574.
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Topics: Cancer , Epidemiology
Munn Z, Pollock D, Stone J, Hasanoff S, Gordon A, Price C, et al. 2024. The impact of using cannabis during pregnancy on the infant and mother: An overview of systematic reviews, evidence map, targeted updates, and de novo synthesis. Austral NZ J Obstet Gynaecol; doi: 10.1111/ajo.13916 . Online ahead of print, December 19, 2024.
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Topics: cannabis , Systematic Review
Xue Y, Wang L, Huo R, Chen M, Melo B, Dingley K , et al. 2024. 1β-Hydroxydeoxycholic acid as an endogenous biomarker in human plasma for assessment of CYP3A clinical drug-drug interaction potential. Drug Metab Dispos 52(9):966–974; doi: 10.1124/dmd.124.001680 . PMID: 38991779.
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Topics: biomarkers , drug interactions
Fender CL , Good SP, Garcia-Jaramillo. 2024. An integrated approach to evaluating water contaminants and evaporation in agricultural water distribution systems. Ecotoxicol Environ Safety 287(15 Nov):117277; doi: 10.1016/j.ecoenv.2024.117277 . PMID: 39515202.
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Topics: spectrometry , water
Oller A, Barroso J, Prieto P, Verougstraete V, Heim K, Henderson R . 2024. Response to letter to editors submitted by PE Rasmussen, P Huntsman, TM Singer, MN Jacobs, and CC Trevithick-Sutton (Aug 2024). Regul Toxicol Pharmacol 154:105740; doi: 10.1016/j.yrtph.2024.105740 . PMID: 39557211.
Topics: Metals
Pennell ML, Wheeler MW , Auerbach SS. 2024. A hierarchical constrained density regression model for predicting cluster‐level dose‐response. Environmetrics 35(7):e2880; doi: 10.1002/env.2880 .
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Topics: Toxicology , transcriptomics
Bates CA, Vincent MJ , Buerger AN , Santamaria AB, Maier A, Jack M. 2024. Investigating the relationship between β-carotene intake from diet and supplements, smoking, and lung cancer risk. Food Chem Toxicol 194:115104; doi: 10.1016/j.fct.2024.115104 . PMID: 39522798.
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Topics: Cancer , Food science , Toxicology
Haber LT, Bradley MA, Buerger AN , Behrsing H, Burla S, Clapp PW, et al. 2024. New approach methodologies (NAMs) for the in vitro assessment of cleaning products for respiratory irritation: Workshop report. Front Toxicol 6:1431790; doi: 10.3389/ftox.2024.1431790 . PMID: 39439531.
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Topics: NAMs , Toxicology
Mattes RD, Rivera BN, Rutigliani GR, Rogers S , Mendoza ID, Wang L, Beckemeier K, Wikoff D . 2024. A review of low- and no-calorie sweetener safety and weight management efficacy. Nutrition Today 59(6):261-288; doi: 10.1097/NT.0000000000000723 .
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Topics: Food science , risk assessment , Toxicology
Madl AK, Donnell MT, Covell LT . 2024. Synthetic vitreous fibers (SVFs): Adverse outcome pathways (AOPs) and considerations for next generation new approach methods (NAMs). Crit Rev Toxicol 54(10:754-804; doi: 10.1080/10408444.2024.2390020 . PMID: 39287182.
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Topics: Cancer
O’Brien J, Mitchell C, Auerbach S, Doonan L, Ewald J, Everett L, Faranda A, Johnson K, Reardon A, Rooney J., Wheeler MW , et al. 2024. Bioinformatic workflows for deriving transcriptomic points of departure: Current status, data gaps, and research priorities. Toxicol Sci 203(2):147-159; doi: 10.1093/toxsci/kfae145 . PMCID: PMC11775421.
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