2018 (62 POSTS)
Beebe-Dimmer JL, Ruterbusch JJ, Bylsma LC , Gillezeau C, Fryzek J, Schultz NM, Flanders SC, Barlev A, et al. 2018. Patterns of bicalutamide use in prostate cancer treatment: A U.S. real-world analysis using the SEER-Medicare database. Adv Ther 35(9):1438-1451; doi: 10.1007/s12325-018-0738-5 . PMID: 29946798.
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Topics: Cancer , drug interactions , Health Economics and Outcomes Research (HEOR)
Harrill AH, Borghoff S , Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ. 2018. NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies. National Toxicology Program Research Report 6, Research Triangle Park, NC.
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Topics: genotoxicity
Casey WM, Chang X, Allen DG, Ceger PC, Choksi NY , Hsieh JH, et al. 2018. Evaluation and optimization of pharmacokinetic models for in vitro to in vivo extrapolation of estrogenic activity for environmental chemicals. Environ Health Perspect 126(9):97001; doi: 10.1289/EHP1655 . PMID: 30192161.
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Topics: modeling , pharmacokinetics , regulatory toxicology
Sacks NC , Sharma A, Cyr PL , Bertiger G, Dahdal DN, Brogadir S. 2018. Real-world comparison of the effectiveness and safety of different bowel preparation agents. Clin Exp Gastroenterol 11(Aug 16):289–299; doi: 10.2147/CEG.S171861 . PMID: 30555250.
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Topics: Cancer , Epidemiology , test methods
Klaren WD , Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342; doi: 10.1089/adt.2018.86 . PMID: 30070899.
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Topics: test methods
Patlewicz G , Wambaugh JF, Felter S, Simon TW, Becker RA. 2018. Utilizing Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a risk-based prioritization approach for thousands of chemicals. Comput Toxicol 7(Aug):58-67; doi: 10.1016/j.comtox.2018.07.002 . PMID: 31338483.
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Topics: modeling , NAMs
Ruzin A, Pastula ST , Levin-Sparenberg EM, Jiang X , Fryzek JP, Tovchigrechko A, Lu B, Qi Y, et al. 2018. Characterization of circulating RSV strains among subjects in the OUTSMART-RSV surveillance program during the 2016-17 winter viral season in the United States. PLoS One 13(7):e0200319; doi: 10.1371/journal.pone.0200319 . PMID: 30040837.
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Topics: Epidemiology
Myatt GJ, Ahlberg E, Akahori Y, Allen D, Amberg A, Anger LT, Aptula A,…, Patlewicz G , et al. 2018. In silico toxicology protocols. Regul Toxicol Pharmacol 96(July):1-17; doi: 10.1016/j.yrtph.2018.04.014 . PMID: 29678766.
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Topics: computational toxicology
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96(Jul):178–189; doi: 10.1016/j.yrtph.2018.05.006 . PMID: 29738809.
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Topics: carcinogens , mode of action , risk assessment
Proctor DM , Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016 . PMID: 29684431.
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Topics: Adverse outcome pathways (AOPs) , Cancer , genotoxicity
Moffat I, Martinova N, Seidel C, Thompson CM . 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044 .
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Topics: chromium , water
Powles MA, Galgoci A, Misura A, Colwell L, Dingley K , Tang W, et al. 2018. In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models. Antimicrob Agents Chemother 62:e02577–17; doi: 10.1128/AAC.02577-17 . PMID: 29866878.
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Topics: modeling
Fitzpatrick JM, Roberts DW, Patlewicz G . 2018. An evaluation of selected (Q)SARs/expert systems for predicting skin sensitization potential. SAR QSAR Environ Res 29(6):439-468; doi: 10.1080/1062936X.2018.1455223 . PMID: 29676182.
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Topics: modeling
Klaren WD , Vine D, Vogt S, Robertson LW. 2018. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433; doi: 10.1007/s11356-017-0202-0 . PMID: 28940161.
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Topics: Metals , PCBs
Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, … Dingley KH , et al. 2018. Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists. ACS Med Chem Lett (9):1088–1093; doi: 10.1021/acsmedchemlett.8b00306 . PMID: 30429950.
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Topics: drug development
Shukla A, Nieman CL, Price C , Harper M, Lin FR, Reed NS. 2018. Impact of hearing loss on patient-provider communication among hospitalized patients: A systematic review. Am J Med Qual 34(3):282–292; doi: 10.1177/1062860618798926 . PMID: 30196712.
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Topics: hearing loss , Systematic Review
Olson A, Frankenfeld CL , Wallace TC, Johnson J. 2018. Assessment of oats and milk on markers of cardiovascular disease: NHANES 1999-2014 datasets. Nutr Today 53(6):293–299; doi: 10.1097/NT.0000000000000308 .
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Topics: Epidemiology , Food science , NHANES , nutrition
Pecquet AM, Martinez JM, Vincent M , Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878; doi: 10.1002/jat.3594 . PMID: 29441599.
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Topics: mode of action
Suh M , Proctor DM , Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006 . PMID: 29689363.
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Topics: carcinogens , chemical safety assessment , consumer products , genotoxicity , microplastics
Sacks NC , Cyr PL , Louie AC, Liu Y , Chiarella MT, Sharma A, Chung KC. 2018. Burden of acute myeloid leukemia among older, newly diagnosed patients: Retrospective analysis of data from the 2010-2012 Medicare limited data set. Clin Ther 40(5):692–703.e2; doi: 10.1016/j.clinthera.2018.03.012 . PMID: 29673891.
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