2018 (52 POSTS)
Wikoff D , Urban JD , Harvey S , Haws LC . 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol 37(2):125-143; doi: 10.1177/1091581818754330.
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Topics: risk assessment , Systematic Review , trichloroethylene
Roberts DW, Patlewicz G . 2018. Non-animal assessment of skin sensitization hazard – Is an integrated testing strategy needed, and if so what should be integrated? J Appl Toxicol 38(1):41-50; doi: 10.1002/jat.3479 . PMID: 28543848.
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Topics: Adverse outcome pathways (AOPs) , modeling
Doepker C , Franke K , Myers E, Goldberger JJ, Lieberman HR, O’Brien C, Peck J, Tenenbein M, Weaver C, Wikoff D . 2018. Key findings and implications of a recent systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Nutrients 10(10):1536; doi: 10.3390/nu10101536 .
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Topics: food safety , Food science , Systematic Review
Rish W , Pfau EJ. 2018. Bounding analysis of drinking water health risks from a spill of hydraulic fracturing flowback water. Risk Analysis 38(4):724-754; doi: 10.1111/risa.12884 .
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Topics: Environmental Science , fracking , risk assessment , water
2017 (58 POSTS)
Schaefer HR , Myers, JL. 2017. Guidelines for performing systematic reviews in the development of toxicity factors. Regul Toxicol Pharmacol 91(Dec):124-141; doi: 10.1016/j.yrtph.2017.10.008 . PMID: 29080853.
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Topics: risk assessment , Systematic Review
Wheeler MW , Dunson DB, Herring AH. 2017. Bayesian local extremum splines. Biometrika 104(4):939-52; doi: 10.1093/biomet/asx039 . PMCID: PMC5798493.
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Topics: Bayesian modeling
Lansita J, Mease KM , Qiu H, Yednock T, Sankaranarayanan S, Kramer S. 2017. Nonclinical development of ANX005: A humanized anti-Clq antibody for treatment of autoimmune and neurodegenerative diseases. Int J Toxicol 36(6)449-462; doi: 10.1177/1091581817740873 . PMID: 29202623.
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Topics: Toxicology
Williams A, Grulke C, Edwards J, McEachran A, Mansouri K, Baker N, Patlewicz G , Shah I, et al. 2017. The CompTox Chemistry Dashboard–A community data resource for environmental chemistry. J Cheminform 9(1):61; doi: 10.1186/s13321-017-0247-6 . PMID: 29185060.
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Topics: computational toxicology
Liu J, Patlewicz G , Williams A, Thomas RS, Shah I. 2017. Predicting organ toxicity using in vitro bioactivity data and chemical structure. Chem Res Toxicol 30(11):2046-2059; doi: 10.1021/acs.chemrestox.7b00084 . PMID: 28768096.
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Topics: computational toxicology , modeling
Wheeler MW , Bailer AJ, Cole T, Park RM, Shao K. 2017. Bayesian quantile impairment threshold benchmark dose estimation for continuous endpoints. Risk Anal 37(11):2107-18; doi: 10.1111/risa.12762 . PMCID: PMC5740488.
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Topics: Bayesian modeling , benchmark dose estimation (BMD) , modeling
Wirbisky-Hershberger SE , Sanchez OF, Horzmann KA, Thanki D, Yuan C, Freeman JL. 2017. Atrazine exposure decreases the activity of DNMTs, global DNA methylation levels, and dnmt expression. Food Chem Toxicol 109(Pt 1):727–734; doi: 10.1016/j.fct.2017.08.041 .
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Topics: atrazine
Monticello TM , Jones TW, Dambach DM, Potter DM, Bolt MW, Liu M, Keller DA, Hart TK, et al. 2017. Current nonclinical testing paradigm enables safe entry to First-in-Human clinical trials: The IQ consortium nonclinical translational database. Toxicol Appl Pharmacol 334(Nov 1):100-109; doi: 10.1016/j.taap.2017.09.006 .
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Topics: nonclinical safety assessment
Pradeep P, Mansouri K, Patlewicz G , Judson RS. 2017. A systematic evaluation of analogs and automated read-across prediction of estrogenicity: A case study using hindered phenols. Comput Toxicol 4(Nov):22-30; doi: 10.1016/j.comtox.2017.09.001 . PMID: 30057968.
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Topics: read-across
Huddle MG, Goman AM, Kernizan FC, Foley DM, Price C , Frick KD, Lin FR. 2017. The economic impact of adult hearing loss: A systematic review. JAMA Otolaryngol: Head Neck Surg 143(10):1040–1048; doi: 10.1001/jamaoto.2017.1243 .
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Topics: hearing loss , Systematic Review
Shao K, Allen BC, Wheeler MW . 2017. Bayesian hierarchical structure for quantifying population variability to inform probabilistic health risk assessments. Risk Anal 37(10):1865-78; doi: 10.1111/risa.12751 .PMCID: PMC6151353.
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Topics: Bayesian modeling , risk assessment
Rager JE, Auerbach SS, Chappell GA, Martin E, Thompson C , Fry RC. 2017. Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort. Chem Res Toxicol 30(10):1911-1920; doi: 10.1021/acs.chemrestox.7b00221 .
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Topics: arsenic , benchmark dose estimation (BMD)
Thompson CM, Suh M, Proctor DM, Haws LC , Harris MA. 2017. Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents. Mutat Res 823(Nov):45-57; doi: 10.1016/j.mrgentox.2017.08.004 .
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Topics: chromium , mode of action
Patlewicz G , Helman G, Pradeep P, Shah I. 2017. Navigating through the minefield of read-across tools: A review of in silico tools for grouping. Comput Toxicol 3(Aug):1-18; doi: 10.1016/j.comtox.2017.05.003 . PMID: 30221211.
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Topics: read-across
Thompson CM , Young RR, Dinesdurage H, Suh M , Harris MA, Rohr AC, Proctor DM . 2017. Assessment of the mutagenic potential of hexavalent chromium in the duodenum of Big Blue® rats. Toxicol Appl Pharmacol 330(1):48-52; 10.1016/j.taap.2017.07.002 .
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