2018 (63 POSTS)
Thompson CT , Suh M , Chappell G, Borghoff S , Ellis-Hutchings, R, Wiench, K, Finch, L, Proctor DM . 2018. Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans. Regul Toxicol Pharmacol 96(Jul):178–189; doi: 10.1016/j.yrtph.2018.05.006 . PMID: 29738809.
View Abstract
Topics: carcinogens , mode of action , risk assessment
Proctor DM , Suh M , Chappell G, Borghoff SJ , Thompson CM , Wiench K, Finch L, Ellis-Hutchings R. 2018. An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events. Regul Toxicol Pharmacol 96(July):30-40; doi: 10.1016/j.yrtph.2018.04.016 . PMID: 29684431.
View Abstract
Topics: Adverse outcome pathways (AOPs) , Cancer , genotoxicity
Moffat I, Martinova N, Seidel C, Thompson CM . 2018. Hexavalent chromium in drinking water. J AWWA 110(5):E22-E35; doi: 10.1002/awwa.1044 .
View Abstract
Topics: chromium , water
Powles MA, Galgoci A, Misura A, Colwell L, Dingley K , Tang W, et al. 2018. In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models. Antimicrob Agents Chemother 62:e02577–17; doi: 10.1128/AAC.02577-17 . PMID: 29866878.
View Abstract
Topics: modeling
Fitzpatrick JM, Roberts DW, Patlewicz G . 2018. An evaluation of selected (Q)SARs/expert systems for predicting skin sensitization potential. SAR QSAR Environ Res 29(6):439-468; doi: 10.1080/1062936X.2018.1455223 . PMID: 29676182.
View Abstract
Topics: modeling
Klaren WD , Vine D, Vogt S, Robertson LW. 2018. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25(17):16427–16433; doi: 10.1007/s11356-017-0202-0 . PMID: 28940161.
View Abstract
Topics: Metals , PCBs
Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, … Dingley KH , et al. 2018. Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists. ACS Med Chem Lett (9):1088–1093; doi: 10.1021/acsmedchemlett.8b00306 . PMID: 30429950.
View Abstract
Topics: drug development
Shukla A, Nieman CL, Price C , Harper M, Lin FR, Reed NS. 2018. Impact of hearing loss on patient-provider communication among hospitalized patients: A systematic review. Am J Med Qual 34(3):282–292; doi: 10.1177/1062860618798926 . PMID: 30196712.
View Abstract
Topics: hearing loss , Systematic Review
Olson A, Frankenfeld CL , Wallace TC, Johnson J. 2018. Assessment of oats and milk on markers of cardiovascular disease: NHANES 1999-2014 datasets. Nutr Today 53(6):293–299; doi: 10.1097/NT.0000000000000308 .
View Abstract
Topics: Epidemiology , Food science , NHANES , nutrition
Pecquet AM, Martinez JM, Vincent M , Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878; doi: 10.1002/jat.3594 . PMID: 29441599.
View Abstract
Topics: mode of action
Suh M , Proctor DM , Chappell G, Rager JE, Thompson CM , Borghoff S , Finch L, Ellis-Hutchings R, Wiench K. 2018. A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicol 402-403(June 1):50-67; doi: 10.1016/j.tox.2018.04.006 . PMID: 29689363.
View Abstract
Topics: carcinogens , chemical safety assessment , consumer products , genotoxicity , microplastics
Sacks NC , Cyr PL , Louie AC, Liu Y , Chiarella MT, Sharma A, Chung KC. 2018. Burden of acute myeloid leukemia among older, newly diagnosed patients: Retrospective analysis of data from the 2010-2012 Medicare limited data set. Clin Ther 40(5):692–703.e2; doi: 10.1016/j.clinthera.2018.03.012 . PMID: 29673891.
View Abstract
Topics: Cancer , Health Economics and Outcomes Research (HEOR)
Patlewicz G , Cronin MTD, Helman G, Lambert JC, Lizarraga LE, Shah I. 2018. Navigating through the minefield of read-across frameworks: A commentary perspective. Comput Toxicol 6(May):39-54; doi: 10.1016/j.comtox.2018.04.002 .
View Abstract
Topics: computational toxicology , NAMs
Schwartz KL, Simon MS, Bylsma LC , Ruterbusch JJ, Beebe-Dimmer JL, Schultz NM, Flanders SC, Barlev A, et al. 2018. Clinical and economic burden associated with stage III to IV triple-negative breast cancer: A SEER-Medicare historical cohort study in elderly women in the United States. Cancer 124(10):2104-2114; doi: 10.1002/cncr.31299 . PMID: 29505670.
View Abstract
Topics: Cancer , Health Economics and Outcomes Research (HEOR)
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ , et al. 2018. Benchmark dose (BMD) modeling: Current practice, issues, and challenges. Crit Rev Toxicol 48(5):387–415; doi: 10.1080/10408444.2018.1430121 . PMID: 29516780.
View Abstract
Topics: benchmark dose estimation (BMD) , modeling
Movva N , Jani A. 2018. The value of pay-for-performance in England: An evaluation of NHS England’s Quality Outcomes Framework. Value in Healthcare Review Working Paper No. 2; University of Oxford Research Archive .
View Abstract
Topics: Health Economics and Outcomes Research (HEOR)
DeGeorge J, Robertson S, Butler L, Derzi M, Stoch SA, Diaz D, Hartke J,…, Greene N . 2018. An industry perspective on the 2017 EMA guideline on first‐in‐human and early clinical trials. Clin Pharm Ther 103(4):566-569; doi: 10.1002/cpt.984 . PMID: 29285748.
View Abstract
Topics: drug development
Clippinger A, Allen D, Jarabek AM, Corvaro M, Gaça M, Gehen S, Hotchkiss JA, Patlewicz G , et al. 2018. Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report. Toxicol In Vitro 48(April):53-70; doi: 10.1016/j.tiv.2017.12.011 . PMID: 29277654.
View Abstract