2012 (44 POSTS)
Finley BL , Monnot AD, Gaffney SH, Paustenbach DJ. 2012. Dose-response relationships for blood cobalt concentrations and health effects: A review of the literature and application of a biokinetic model. J Toxicol Environ Health B, 15(8):493–523; doi: 10.1080/10937404.2012.744287 .
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Topics: cobalt , modeling
Knutsen JS, Kerger BD, Finley BL , Paustenbach DJ. 2012. A calibrated human PBPK model for benzene inhalation with urinary bladder and bone marrow compartments. Risk Anal 33 (7):1237–1251; doi: 10.1111/j.1539-6924.2012.01927.x . PMID: 23278103.
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Topics: benzene , modeling , PBPK/PBDE
Finley BL , Pierce JS, Phelka AD, Adams RE, Paustenbach DJ, Thuett KA, Barlow CA. 2012. Evaluation of tremolite asbestos exposures associated with the use of commercial products. Crit Rev Toxicol 42(2):119–146; doi: 10.3109/10408444.2011.636028 . PMID: 22141364.
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Topics: asbestos , Exposure Assessment
Finley BL , Monnot AD, Paustenbach DJ, Gaffney SH. 2012. Derivation of a chronic reference dose for cobalt. Regul Toxicol Pharmacol 64(3):491–503; doi: 10.1016/j.yrtph.2012.08.022 . PMID: 22982439.
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Topics: cobalt
Fowler, JC, Bhattacharya S, Urban JD , Vaidehi N, Mailman RB. 2012. Receptor conformations involved in dopamine D2L receptor functional selectivity induced by selected transmembrane 5 serine mutations. Mol Pharmacol 81(6):820-831; doi: 10.1124/mol.111.075457 . PMID: 22416052.
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Topics: pharmacokinetics
Henderson RG , Cappellini D, Seilkop SK, Bates HK, Oller AR. 2012. Oral bioaccessibility testing and read-across hazard assessment of nickel compounds. Regul Toxicol Pharmacol 63(1):20-28; doi: 10.1016/j.yrtph.2012.02.005 . PMID: 22369872.
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Topics: Metals , nickel , risk assessment
Fillos D, Scott LLF, Anderle De Sylor M, Grespin M, Luksemburg WJ, Finley B . 2012. PCB concentrations in shrimp from major import markets and the United States. Environ Toxicol Chem 31(5):1063–1071; doi: 10.1002/etc.1803 . PMID: 22407850.
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Topics: Food science , PCBs
Boekelheide K, Blumberg B, Chapin RE, Cote I, Graziano JH, Janesick A, Lane R, Lilycrop K, Myatt L, States JC, Thayer KA, Waalkes MP, Rogers JM . 2012. Predicting later-life outcomes of early-life exposures. Environ Health Perspect 120:1353–1361; doi: 10.1289/ehp.1204934 .
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Topics: arsenic , Epidemiology , Exposure Assessment
Schugg TT, Erlebacher A, Leibowitz S, Ma L, Muglio LJ, Rando OJ, Rogers JM , Romero R, von Saal FS, Wise LD. 2012. Fetal programming and environmental exposures: Implications for prenatal care and preterm birth. Ann NY Acad Sci 1276(1):37–46; doi: 10.1111/nyas.12003 .
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Topics: Exposure Assessment
Hinerman JM , Dignam JD, Mueser T. 2012. Models for the binary complex of bacteriophage T4 Gp59 helicase loading protein: G32 single-stranded DNA-binding protein and ternary complex with pseudo-Y junction DNA. J Biol Chem 287(22):8608–8617; doi: 10.1074/jbc.M111.333476 . PMID: 22493434.
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Topics: modeling
Mease K , Sane RS, Podila L, Taub ME. 2012. Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: A strategy to assess the interaction of a new chemical entity with P-gp, BCRP and MRP2. J Pharm Sci 101(5):1888–1897; doi: 10.1002/jps.23069 . PMID: 22359351.
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Topics: drug interactions , modeling
Wang A, Halbert RJ, Baerwaldt T, Nordyke RJ . 2012. U.S. payer perspectives on evidence for formulary decision-making. J Oncol Pract 8(3 Suppl):22s-27s; doi: 10.1200/JOP.2011.000526 . PMID: 22942820.
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Topics: drug development , Health Economics and Outcomes Research (HEOR)
Dobo KL, Greene N , Fred C, Glowienke S, Harvey JS, Hasselgren C, Jolly R, Kenyon MO, et al. 2012. In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey. Regul Toxicol Pharmacol 62(3):449-455; doi: 10.1016/j.yrtph.2012.01.007 . PMID: 22321701.
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Topics: computational toxicology , genotoxicity
Racz L , Muller JG, Goel RK. 2012. Fate of selected estrogens in two laboratory scale sequencing batch reactors fed with different organic carbon sources. Bioresource Technol 110(April):35–41; doi: 10.1016/j.biortech.2012.01.059 . PMID: 22382291.
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Topics: computational toxicology
Henderson RG , Durando J, Oller A, Merkel DJ, Marone PA, Bates HK. 2012. Acute oral toxicity of nickel compounds. Regul Toxicol Pharmacol 62(3):425-432; doi: 10.1016/j.yrtph.2012.02.002 . PMID: 22333739.
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Topics: Metals , nickel
Mwanza JC, Lyke DF, Hertzberg RC, Haber L, Kohrman-Vincent M , Li R, et al. 2012. Cholinesterase inhibition and depression of the photic after discharge flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxur. Neurotoxicol 33(3):332–346; 10.1016/j.neuro.2012.02.006 .
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Topics: Exposure Assessment
Maier A, Kohrman-Vincent M , Hertzberg R, Allen B, Haber LT, Dourson M. 2012. Critical review of dose-response options for F344 rat mammary tumors for acrylamide – Additional insights based on mode of action. Food Chem Toxicol 50(5):1763–1776; doi: 10.1016/j.fct.2012.02.002 .
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Topics: mode of action
Thompson CM , Proctor DM , Harris MA. 2012. Duodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI). Toxicol Sci 126(1):287-288; doi: 10.1093/toxsci/kfr337 .
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Topics: chromium
Wang X, Greene N . 2012. Comparing measures of promiscuity and exploring their relationship to toxicity. Molec Inform 3(2):145-159; doi: 10.1002/minf.201100148 . PMID: 27476959. Awarded Best Paper of 2012 by the editors of Molecular Informatics .
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Topics: computational toxicology , pharmacology
Kopec AK, Kim S, Forgacs AL, Zacharewski TR, Proctor DM , Harris MA, Haws LC , Thompson CM. 2012. Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water. Toxicol Appl Pharmacol 259(1):13-26; doi: 10.1016/j.taap.2011.11.012 . PMID: 22155349.
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