2012 (43 POSTS)
Mwanza JC, Lyke DF, Hertzberg RC, Haber L, Kohrman-Vincent M , Li R, et al. 2012. Cholinesterase inhibition and depression of the photic after discharge flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxur. Neurotoxicol 33(3):332–346; 10.1016/j.neuro.2012.02.006 .
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Topics: Exposure Assessment
Maier A, Kohrman-Vincent M , Hertzberg R, Allen B, Haber LT, Dourson M. 2012. Critical review of dose-response options for F344 rat mammary tumors for acrylamide – Additional insights based on mode of action. Food Chem Toxicol 50(5):1763–1776; doi: 10.1016/j.fct.2012.02.002 .
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Topics: mode of action
Thompson CM , Proctor DM , Harris MA. 2012. Duodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI). Toxicol Sci 126(1):287-288; doi: 10.1093/toxsci/kfr337 .
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Topics: chromium
Wang X, Greene N . 2012. Comparing measures of promiscuity and exploring their relationship to toxicity. Molec Inform 3(2):145-159; doi: 10.1002/minf.201100148 . PMID: 27476959. Awarded Best Paper of 2012 by the editors of Molecular Informatics .
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Topics: computational toxicology , pharmacology
Kopec AK, Kim S, Forgacs AL, Zacharewski TR, Proctor DM , Harris MA, Haws LC , Thompson CM. 2012. Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water. Toxicol Appl Pharmacol 259(1):13-26; doi: 10.1016/j.taap.2011.11.012 . PMID: 22155349.
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Topics: chromium , water
Urban J , Budinsky R, Rowlands J. 2012. An evaluation of single nucleotide polymorphisms in the human heat shock protein 90kDa alpha and beta isoforms. Drug Metab Pharmacokinet 27(2):268-278; doi: 10.2133/dmpk.DMPK-11-SC-114 . PMID: 22185817.
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Topics: pharmacokinetics
Thompson CM , Proctor DM , Suh M , Haws LC , Hebert CD, Mann JF, Shertzer HG, Hixon JG, Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90; doi: 10.1093/toxsci/kfr280 . PMID: 22011396.
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Topics: carcinogens , chromium , mode of action , water
2011 (32 POSTS)
Taub ME, Mease K , Sane RS, Watson CA, Chen L, Ellens H, Hirakawa B, Reyner EL, et al. 2011. Digoxin is not a substrate for organic anion transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium dependent transporter expressed in HEK293 cells. Drug Metab Disp 39(11):2093–2102; doi: 10.1124/dmd.111.040816 . PMID: 21849517.
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Topics: drug interactions
Robison TW . 2011. Dealing with positive in vitro mammalian cell genotoxicity assays. Inter Drug Discovery 6(5):40-43 .
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Topics: genotoxicity , mode of action
Enayetallah AE, Ziemek D, Leininger MT, Randhawa R, Yang J, Manion TB, Mather DE,…, Greene N , et al. 2011. Modeling the mechanism of action of a DGAT1 inhibitor using a causal reasoning platform. PLoS One 6(11):e27009; doi: 10.1371/journal.pone.0027009 . PMID: 22073239.
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Topics: diabetes , mode of action
Tichomirowa MA, Bariler A, Daly AF, Jaffrain-Rea M-L, Ronchi CL, Yaneva M, Urban JD , Petrossians P, et al. 2011. High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas. Eur J Endocrinol 165(4):509-515; doi: 10.1530/EJE-11-0304 . PMID: 21753072.
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Topics: genotoxicity
Thompson CM , Proctor DM , Haws LC , Hebert CD, Grimes SD, Shertzer HG, Kopec AK, Hixon JG, Zacharewski TR, Harris MA. 2011. Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium. Toxicol Sci 123(1):58-70; doi: 10.1093/toxsci/kfr164 . PMID: 21712504.
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Topics: chromium , mode of action
Shum M, Kelsh MA , Sheppard AR, Zhao K. 2011. An evaluation of self-reported mobile phone use compared to billing records among a group of engineers and scientists. Bioelectromagnetics 32(1):37–48.
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Topics: Electric and Magnetic Fields (EMF) , Epidemiology
Lau EC, Mowat FS, Kelsh MA , Legg JC, Engel-Nitz NM, Watson HN, et al. 2011. Use of electronic medical records (EMR) for oncology outcomes research: Assessing the comparability of EMR information to patient registry and health claims data. Clin Epidemiol 3:259–272.
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Topics: Cancer , Epidemiology
Bogeberg M, Vivanco S , Carmona-Galindo V. 2011. Relationship between soil sodium concentration and plant height in Salicornia virginica in the Ballona Wetlands in Los Angeles, CA. BIOS 82(4):112–116.
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Topics: Environmental Science
Greene N , Song M. 2011. Predicting in vivo safety characteristics using physicochemical properties and in vitro assays. Fut Med Chem 3(12):1503-1511; doi: 10.4155/fmc.11.89 . PMID: 21882943.
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Topics: chemical safety assessment , drug development
Sheehan PJ, Brorby GP , Berman DW, Bogen KT, Holm SE. 2011. Chamber for testing asbestos-containing products: Validation and testing of a re-created chrysotile-containing joint compound. Ann Occup Hyg 55(7):797-809; doi: 10.1093/annhyg/mer048 . PMID: 21795244.
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Topics: asbestos
Dobrovolsky VN, Elespuru RK, Bigger CA, Robison TW , Heflich RH. 2011. Monitoring humans for somatic mutation in the endogenous PIG-a gene using red blood cells. Environ Mol Mutagen 52(9):784-94; doi: 10.1002/em.20667 .
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