2023 (46 POSTS)
Du H, Pan B, Alund AW, Yan J, Chen Y, Robison TW , Chen T. 2023. Evaluation of mutagenic susceptibility of different stages in germ cell development of Caenorhabditis elegans using whole genome sequencing. Arch Toxicol 97(8):2261-2272; doi: 10.1007/s00204-023-03526-z .
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Topics: genome sequencing
Buerger AN , Massarsky A, Russell A, Zoghby N, Hirn C, Mucs D, et al. 2023. Evaluation of chemical grouping workflows for flavor inhalation risk assessment: Selected furan moiety-containing chemicals as a case study. Comp Tox 26(May):100269; doi: 10.1016/j.comtox.2023.100269 .
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Topics: risk assessment , Toxicology
Meek ME, Wikoff D . 2023. The need for good practice in the application of mechanistic constructs in hazard and risk assessment. Toxicol Sci 194(1):13-22; doi: 10.1093/toxsci/kfad039 . PMID: 3707944.
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Topics: risk assessment , Toxicology
Kaurani P, Hindocha AD, Jayasinghe RM, Pai UY, Batra K, Price C . 2023. Effect of addition of titanium dioxide nanoparticles on the antimicrobial properties, surface roughness and surface hardness of polymethyl methacrylate: A systematic review. F1000Res 12:577; doi: 10.12688/f1000research.130028.1 .
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Topics: nanomaterials , nanotechology , Systematic Review , titanium dioxide
Wheeler MW . 2023. An investigation of non-informative priors for Bayesian dose-response modeling. Regul Toxicol Pharmacol 141(June):105389; doi: 10.1016/j.yrtph.2023.105389 . PMCID: PMC10436774.
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Topics: dose-response , modeling
Dalvi T, Nørgaard M, Fryzek JP, Movva N , Pedersen L, Hansen HP, et al. 2023. Biomarker expression and survival in patients with non-small cell lung cancer receiving adjuvant chemotherapy in Denmark. PLoS ONE 18(4):e0284037; doi: 10.1371/journal.pone.0284037 . PMID: 37040387.
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Topics: Cancer , Epidemiology
Thompson CM , Heintz MM , Wolf JC, Cheru R, Haws LC , Cullen JM. 2023. Assessment of mouse liver histopathology following exposure to HFPO-DA with emphasis on understanding mechanisms of hepatocellular death. Toxicol Pathol 51(1–2):4–14; doi: 10.1177/01926233231159078 . PMID: 36987989.
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Topics: Exposure Assessment , Toxicology
Heintz MM , Haws LC , Klaunig JE, Cullen JM, Thompson CM . 2023. Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans. Toxicol Sci 192(1):15–29; doi: 10.1093/toxic/kfad004 . PMID: 36629480.
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Topics: Cancer , Toxicology
Thompson CM , Proctor DM , Harris MA. 2023. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data.” Environ Mol Mutagen 64(4):259–260; doi: 10.1002/em.22537 . PMID: 36916184.
Topics: Hexavalent Chromium , Toxicology
Sterner TR, Covington TR , Mattie DR. 2023. Complex mixtures: Array PBPK modeling of jet fuel components. Toxics 11(2):187; doi: 10.3390/toxics11020187 . PMID: 36851061.
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Topics: PBPK , Toxicology
Wheeler MW , Lim S, House JS, Shockley KR, Bailer AJ, Fostel J, Yang L, Talley D, Raghuraman A, Gift JS. 2023. ToxicR: A computational platform in R for computational toxicology and dose–response analyses. Comp Toxicol 25(Feb):100259; doi: 10.1016/j.comtox.2022.100259 . PMCID: PMC9997717.
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Topics: benchmark dose estimation (BMD) , computational toxicology
East A , Dawson DE, Brady S, Vallero DA, Tornero-Velez R. 2023. A scoping assessment of implemented toxicokinetic models of per- and polyfluoro-alkyl substances, with a focus on one-compartment models. Toxics 11(2):163; doi: 10.3390/toxics11020163 . PMID: 36851038.
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Topics: modeling , PFAS , Toxicology
Grover A, Sankaranarayanan S, Mathur V, Suri P, Qiu H, Andrews-Zwilling Y, Mease K , Taylor LK, Cahir-McFarland E, Keswani S, Yednock T. 2023. Pharmacokinetic and target engagement measures of ANX007, an anti-C1q antibody fragment, following intravitreal administration in nonhuman primates. Invest Opthalmol Visual Sci 64(2)3; 10.1167/iovs.64.2.3 . PMID: 36729444.
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Topics: pharmacokinetics , Toxicology
Borghoff SJ , Cohen SS, Jiang X , Lea IA , Klaren WD , Chappell GA, Britt JK , Rivera BN , Choksi NY , Wikoff DS . 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549 . PMID: 36493943.
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Topics: aspartame , carcinogens , Food science , Systematic Review , Toxicology
Bullano M, Cool C, Schultz BG, Durgapal S, Sacks N , Liu Y , Kee R, Batt K. 2023. Evaluating the financial impact of utilizing recombinant porcine factor VIII or recombinant FVIIa for patients with acquired hemophilia A. Expert Rev Phamacoecon Outcome Res 23(2):225-230; doi: 10.1080/14737167.2023.2160705 . PMID: 36537696.
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Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
2022 (71 POSTS)
Doepker C, Movva N, Cohen SS, Wikoff DS . 2022. Benefit-risk of coffee consumption and all-cause mortality: A systematic review and disability adjusted life year analysis. Food Chem Toxicol 170(Dec):113472; doi: 10.1016/j.fct.2022.113472 . PMID: 36243217.
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Topics: Food science , Systematic Review , Toxicology
Boles C, Zisook R, Buerger AN , Hamaji C, Mathis C, Lauer D, et al. 2022. Semi-quantitative microbial risk assessment: A narrative review and proposed framework for health and safety practitioners. J Pub Health Emerg 6(Dec 25):34; doi: 10.21037/jphe-22-1 .
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Topics: risk assessment , Toxicology
Broome CM, Hooda N , Su J, Jiang X , Nicholson G, Frankenfeld CL , Iglesias-Rodriguez M, Fryzek J, Patel Parija. 2022. Medically-attended anxiety and depression is increased among newly diagnosed patients with cold agglutinin disease: Analysis of an integrated claim-clinical cohort in the United States. PLoS One 17(12):e0276617; doi: 10.1371/journal.pone.0276617 . PMID: 36520848.
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Topics: Epidemiology
Cardosi L, Rau R, Emdem MR, Kemp R, Minshall M, Pontenani F, Provision S, Sacks N . 2022. Healthcare resource utilization in non-cystic fibrosis bronchiectasis (NCFB) patients with commercial insurance coverage in the US. Value in Health 25(12):S89-S90; doi: 10.1016/j.jval.2022.09.437 .
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