Publications

Mihalchik A. Strategies to evaluate over-the-counter drug degradants. Abstract 1252, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Lea IA, Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ. 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221. PMID: 40041033.

Lea IA, Buerger AN, Feifarek D, Mihalchik A, Heintz MM, Haws LC, Nyambego H, Goyak K, Palermo C, Borghoff SJ. 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220. PMID: 40092461.

Mihalchik AL, Choksi NY, Roe AL, Wisser M, Whitaker K, Seibert D, Deore M, Pavlick L, Wikoff DS. 2024. Safety evaluation of 8 drug degradants present in over-the-counter cough and cold medications. Regul Toxicol Pharmacol 149(May):105621; doi: 10.1016/j.yrtph.2024.105621. PMID: 38608922.

Borghoff SJ, Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Lea IA. Evaluation of the endocrine disrupting potential of di-isononyl phthalate. Abstract 3931, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. 

Lea IA, Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Borghoff SJ. Evaluation of the endocrine disrupting potential of di-isodecyl phthalate. Abstract 3930, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Petrick J, Mihalchik A, Tiwary A, Kreidl L, Swartz C, Bhattarai N. Nonclinical safety evaluation of 1-monoacetin and 2-monoacetin as potential impurities in pharmaceutical excipients. Abstract 3107, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Mihalchik A, Wood M. Considerations for standardization and derivation of pediatric and neonatal tolerable exposure limits for extractable and leachable compounds from medical devices. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Tice RR, Bassan A, Amberg A, Anger LT, Beal MA, Bellion P, Benigni R, Birmingham J…, Mihalchik-Burhans AL, et al. 2021. In silico approaches in carcinogenicity hazard assessment: Current status and future needs. Comp Toxicol 20(Nov):100191; doi: 10.1016/j.comtox.2021.100191.

Rogers EN, Mihalchik AL, Gad, SC. Comparison and analysis of discrepancies among commonly used Cramer decision tree methods in Toxtree software.  Abstract no. 1517. Society of Toxicology 59th Annual Meeting, Virtual, 2020.

Mihalchik-Burhans AL, Rogers EN. 2019. Considerations for leachables and extractables testing. In: Gad S (ed), Integrated Safety and Risk Assessment for Medical Devices and Combination Products, pp. 239–263. Springer.

Mihalchik-Burhans AL, Sullivan DW. 2019. Bridging issues of route. In: Gad S (ed), Integrated Safety and Risk Assessment for Medical Devices and Combination Products, pp. 273–297. Springer.

Mihalchik AL, Rogers EN, Gad-McDonald SE, Sullivan DW Jr, Gad SC. Development of dermal permissible daily exposure (PDE) levels for elemental impurities by utilizing data from alternative routes. Poster presented at Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

Mihalchik-Burhans A. And you want this by when? Making the successful transition from the bench to consulting. Oral presentation at the American College of Toxicology 39th Annual Meeting, West Palm Beach, FL, November 2018.

Mihalchik AL, Rogers EN. 2018. Classes of compounds with GI tract toxicity. Chapter 13 in: Gad SC (ed), Toxicology of the Gastrointestinal Tract. CRC Press.

Mihalchik AL. Effects of nitrogen-doped and pristine multi-walled carbon nanotubes in human bronchial epithelial cells and lung fibroblasts. Presented at the Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

Sisler JD, Li R, McKinney W, Mercer RR, Ji Z, Xia T, Wang X, Shaffer J, Orandle M, Mihalchik AL, Battelli L. 2016. Differential pulmonary effects of CoO and La₂O₃ metal oxide nanoparticle responses during aerosolized inhalation in mice. Particle Fibre Toxicol 13(1):42; doi: 10.1186/s12989-016-0155-3.

Sisler JD, Pirela SV, Shaffer J, Mihalchik AL, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, Demokritou P, Qian Y. 2016. Toxicological assessment of CoO and La₂O3 metal oxide nanoparticles in human small airway epithelial cells. Toxicol Sci 150(2):418-428; doi: 10.1093/toxsci/kfw005.

Mihalchik AL, Ding W, Porter D, McLoughlin C, Schwegler-Berry D, Sisler JD, Stefaniak A, Snyder-Talkington BN, Cruz-Silva R, Terrones M, Tsuruoka S, Endo M, Castranova V, Qian Y. Effects of pristine and nitrogen-doped multiwalled carbon nanotubes (ND-MWCNT) on reactive oxygen species (ROS) and cell cycle progression. Poster presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Mihalchik AL, Ding W, Porter D, McLoughlin C, Schwegler-Berry D, Sisler JD, Stefaniak A, Snyder-Talkington BN, Cruz-Silva R, Terrones M, Tsuruoka S, Endo M, Castranova V, Qian Y. 2015. Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells. Toxicology 333(July 3):25–36; doi: 10.1016/j.tox.2015.03.008.