Publications

Proctor D, Thompson C. Why oral cavity tumors should not be the basis of the hexavalent chromium oral cancer slope factor-weight of evidence review. Abstract 3136, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Lipworth L, Panko JM, Allen BC, Mumma MT, Jiang X, Vincent MJ, Bare JL, Antonijevic T, Vivanco SN, Marano DE, Suh M, Cohen S, Mittal L, Proctor DM. 2025. Lung cancer mortality among aircraft manufacturing workers with long-term, low-level, hexavalent chromium exposure. J Occup Environ Hyg 22(3):214-227; doi: 10.1080/15459624.2024.2439817. PMID: 39773194.

Suh M, Mittal L, Brorby G, Pastula S, Vincent M, Proctor D. Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas. International Society of Exposure Science, Montreal, Canada, October 2024.

Perry CS, Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698. PMID: 39251127.

Mittal L, Perry CS, Blanchette AD, Proctor DM. 2024. Probabilistic risk assessment of residential exposure to electric arc furnace steel slag using Bayesian model of relative bioavailability and PBPK modeling of manganese. Risk Anal. 44(9):2169-2186. doi: 10.1111/risa.14309. PMID: 38622492.

Perry CS, Vivanco SN, Verwiel AH, Proctor DM. Derivation of manganese 24-hour acute inhalation guideline protective of respiratory and neurological effects. Abstract 4751, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Allen B, Vincent M, Lipworth L, Panko J, Suh M, Jiang X, Mumma MT, Proctor D. Lung cancer risk and exposure to hexavalent chromium: Results of extended mortality study of workers with low level exposures and quantitative risk assessment using pooled analysis of three cohorts. Poster presentation at Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

Racz L, Mittal L, Perry CS, Blanchette A, Proctor D. Assessing sustainable applications of electric arc furnace steel slag as construction aggregate: Applications of probabilistic risk assessment and physiologically-based pharmacokinetic modeling. Poster presented at Society of Environmental Toxicology and Chemistry North America 44^th Annual Meeting, Louisville, KY, November 2023.

Perry CS, Blanchette AD, Vivanco SN, Verwiel AH, Proctor DM. 2023. Use of physiologically based pharmacokinetic modeling to support development of an acute (24-hour) health-based inhalation guideline for manganese. Regul Toxicol Pharmacol 145:105518; doi: 10.1016/j.yrtph.2023.105518. PMID: 3786341.

Proctor DM, Vivanco SN, Blanchette AD. 2023. Manganese relative oral bioavailability in electric arc furnace steel slag is influenced by high iron content and low bioaccessibility. Toxicol Sci 193(2):234–243; doi: 10.1093/toxsci/kfad037. PMID: 37074943.

Thompson CM, Proctor DM, Harris MA. 2023. Letter to “Chepelev et al. Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data.” Environ Mol Mutagen 64(4):259–260; doi: 10.1002/em.22537. PMID: 36916184.

Perry C, Proctor D. Short-term environmental inhalation toxicity criteria for airborne manganese protective of neurological and respiratory effects for use in air toxics risk assessment. Presentation 5-15.T-04 to Society of Environmental Toxicology and Chemistry, Pittsburgh PA, November 2022.

Proctor D, Mittal L, Vivanco S, Perry C, Blanchette A. Probabilistic health risk assessment for residential exposures to metals in electric arc furnace (EAF) steel slag. Presentation 5.15.P-Th123 to Society of Environmental Toxicology and Chemistry, Pittsburgh PA, November 2022.

Proctor DM, Antonijevic T. Refined health risk assessment for residential exposures to manganese in EAF steel slag. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

Thompson CM, Chappell GA, Mittal L, Gorman B, Proctor DM, Haws LC, Harris MA. Use of targeted mode-of-action research to inform human health risk assessment of hexavalent chromium. Poster presented at Society of Toxicology Annual Meeting, San Diego, CA, March 2022.

Proctor DM, Bhat V, Suh M, Reichert H, Jiang X, Thompson CM. 2021. Inhalation cancer risk assessment for environmental exposure to hexavalent chromium: Comparison of margin-of-exposure and linear extrapolation approaches. Regul Toxicol Pharmacol 124(August):104969; doi: 10.1016/j.yrtph.2021.104969. PMID: 34089813.

Bhat VS, Cohen SM, Gordon EB, Wood CE, Cullen JM, Harris MA, Proctor DM, Thompson CM. 2020. An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: A case study with hexavalent chromium, captan, and folpet. Crit Rev Toxicol 50(8)685-706; doi: 10.1080/10408444.2020.1823934.

Thompson CM, Donahue DA, Hobbs C, Costecalde Y, Franzen A, Suh M, Proctor DM, Harris MA. 2020. Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice. Regul Toxicol Pharmacol 116:104729; doi: 10.1016/j.yrtph.2020.104729.

Suh M, Verwiel A, Proctor D. Oral and inhalation bioaccessibility of cobalt and nickel in metal alloys: A critical consideration for site-specific human health risk assessments and read across. Poster for Society of Toxicology 59th Annual Meeting, Virtual, 2020.

Proctor D. Use of the latest science in cancer risk assessment for hexavalent chromium: Is it time to step away from the default regulatory approaches? Invited presentation to the International Union of Toxicology (IUTOX) / International Congress of Toxicology (ICT) meeting, Honolulu, HI, June 2019.