Publications

Wikoff D, Borghoff S, Rager J, Harvey S, Haws L. 2016. A systematic review of the mechanistic evidence of tetrabromobisphenol TBBPA as a human carcinogen according to the ten key characteristics of carcinogens (TKCC) identified by Smith et al. (2016). PROSPERO 2016:CRD42016046429.

Haws L. Vapor intrusion – Solid ground or quick sand? Invited Speaker. Presented at the 28th Annual Texas Environmental Superconference, Austin, TX, August 2016.

Haws L. Vapor intrusion – Technical issues. Invited Speaker. Presented at the Semi-Annual South Central Regional Meeting of the Auditing Roundtable, Austin, TX, August 2016.

Kirman CR, Suh M, Hays SM, Gürleyük H, Gerads R, De Flora S, Parker W, Lin S, Haws LC, Harris MA, Proctor DM. 2016. Reduction of hexavalent chromium by fasted and fed human gastric fluid.  II. Ex vivo gastric reduction modeling. Toxicol Appl Pharmacol 306:120-133.

Haws L. Trichlorethylene exposure and development of fetal cardiac malformations: What do the data tell us about inhalation exposures resulting from vapor intrusion and potential health risks to pregnant women? – Introduction. Presented at the Society of Toxicology’s 55th Annual Meeting, New Orleans, LA, March 2016.

Wikoff D, Borghoff SJ, Rager JE, Haws LC. Human relevance assessment of tetrabromobisphenol-A (TBBPA) induced uterine adenocarcinomas: Mode of action dependent on high dose molecular initiating event (MIE). Presented in the “Flame Retardants” session at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

Borghoff SJ,  Wikoff D, Rager JE, Haws LC. Tetrabromobisphenol A (TBBPA); Dose- and time-dependent changes in plasma TBBPA and its conjugates over 28 days of administration. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

Thompson CM, Suh M, Proctor DM, Rager JE, Haws LC, Harris MA. Assessment of the in vivo genotoxicity of CrVI in target organs identified in a two-year cancer bioassay. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

Wikoff DS, Rager JE, Haws LC, Borghoff SJ. 2016. A high dose mode of action for tetrabromobisphenol A-induced uterine adenocarcinomas in Wistar Han rats: A critical evaluation of key events in an adverse outcome pathway framework. Regul Toxicol Pharmacol 77(June):143-159. doi: 10.1016/j.yrtph.2016.01.018.

Borghoff SJ, Wikoff D, Harvey S, Haws L. 2016. Dose- and time-dependent changes in tissue levels of tetrabromobisphenol A (TBBPA) and its sulfate and glucuronide conjugates following repeated administration to female Wistar Han Rats. Toxicol Rep 3:190-201. doi: 10.1016/j.toxrep.2016.01.007.

Urban JD, Thompson CM, Plunkett LM, Perry CS, Haws LC. A state of the science copper reference dose for soil remediation. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Harris MA, Thompson CM, Proctor DM, Suh M, Wolf JC, Seiter JM, Chappell MA, Haws LC. Analysis of duodenal crypt health following exposure to Cr(VI) in drinking water. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Borghoff SJ, Wikoff D, White MC, Thompson C, Haws LC. Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

Wikoff D, White MC, Borghoff SJ, Haws LC. Evaluation of tetrabromobisphenol A (TBBPA)-induced endocrine-related target gene activity using high-throughput screening data from ToxCast. Presented at the Society of Toxicology’s 54th Annual Meeting, San Diego, CA, March 2015.

Thompson CM, Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M, Proctor DM, Bichteler A, Haws LC, Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66.

Thompson CM, Seiter J, Chappell MA, Tappero RV, Proctor DM, Suh M, Wolf JC, Haws LC, Vitale R, Mittal L, Kirman CR, Hays SM, Harris MA. 2015. Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water. Toxicol Sci 143(1):16-25.

Haws LC, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Wikoff D. Development of non-cancer based toxicity factors and daily dose estimates for TBBPA. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.

Kirman CR, Proctor D, Suh M, Thompson CM, Harris MA, Haws LC, Hays SM. Variation analysis of PBPK model parameters for describing the delivery of Cr(VI) to the small intestines of humans. Presented at the Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.

Thompson CM, Proctor DM, Suh M, Wolf JC, Haws LC, Seiter JM, Chappell MA, Harris MA. X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.

Wikoff D, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Haws LC. Development of an oral cancer slope factor and lifetime average daily dose estimates for TBBPA. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.