2015 (6 POSTS)
Borghoff SJ , Wikoff D , White MC, Thompson C , Haws LC . Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.
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Topics: flame retardants
Thompson CM , Seiter J, Chappell MA, Tappero RV, Proctor DM , Suh M , Wolf JC, Haws LC , Vitale R, Mittal L , Kirman CR, Hays SM, Harris MA. 2015. Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water. Toxicol Sci 143(1):16-25; doi: 10.1093/toxsci/kfu206 . PMID: 25352572.
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Topics: chromium , water
2014 (8 POSTS)
Haws LC, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Wikoff D . Development of non-cancer based toxicity factors and daily dose estimates for TBBPA. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: Cancer , flame retardants
Kirman CR, Proctor D, Suh M, Thompson CM , Harris MA, Haws LC , Hays SM. Variation analysis of PBPK model parameters for describing the delivery of Cr(VI) to the small intestines of humans. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: chromium , modeling , PBPK/PBDE
Thompson CM , Kirman CR, Proctor DM , Haws LC , Suh M , Hays S, Hixon JG, Harris MA. 2014. A chronic oral reference dose for hexavalent chromium-induced intestinal cancer. J Appl Toxicol 34(5):525-536. doi: 10.1002/jat.2907 . PMID: 23943231.
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Topics: Cancer , chromium
Thompson CM , Proctor DM , Suh M, Wolf JC, Haws LC , Seiter JM, Chappell MA, Harris MA. X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: chromium , water
Suh M , Thompson C , Kirman C, Carakostas M, Haws LC , Harris M, Proctor D . 2014. High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice. Food Chem Toxicol 65(Mar):381-388; doi: 10.1016/j.fct.2014.01.009 . PMID: 24418189.
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Topics: chromium , water
Wikoff D, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Haws LC . Development of an oral cancer slope factor and lifetime average daily dose estimates for TBBPA. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
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Topics: Cancer , flame retardants
Bunch AG, Perry CS, Abraham L, Wikoff DS, Tachovsky JA, Hixon JG, Urban JD, Harris MA, Haws LC . 2014. Evaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks. Sci Tot Environ 468-469(Jan 15):832-842; doi: 10.1016/j.scitotenv.2013.08.080 . PMID: 24076504.
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Topics: Air Quality , Exposure Assessment , VOCs
Urban JD, Wikoff DS, Bunch ATG, Harris MA, Haws LC . 2014. A review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels. Sci Tot Environ 466-467:(Jan 1)586-597; doi: 10.1016/j.scitotenv.2013.07.065 . PMID: 23955251.
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Topics: dioxin , Environmental Science
2013 (11 POSTS)
Thompson CM , Gaylor DW, Tachovsky JA, Perry C , Carakostas MC, Haws LC . 2013. Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. J Appl Toxicol 33(12):1395-1406; doi: 10.1002/jat.2799 . PMID: 22936336.
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Topics: benchmark dose estimation (BMD) , modeling , water
Dourson ML, Gadagbui B, Griffin S, Garabrant DH, Haws LC , Kirman C, Tohyama C. 2013. The importance of problem formulations in risk assessment: A case study involving dioxin-contaminated soil. Regul Toxicol Pharmacol 66(2):208-216; doi: 10.1016/j.yrtph.2013.03.010 . PMID: 23545073.
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Topics: dioxin , risk assessment
Urban JD, Thompson CM, Deskin R, Waite M, Haws LC . 2013. Development of an oral cancer slope factor for acrylamide based on tumors relevant to humans. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: Cancer , Exposure Assessment
Kirman CR, Aylward LL, Suh M , Harris MA, Thompson CM , Haws LC , Proctor DM , Lin SS, et al. 2013. Physiologically based pharmacokinetic model for humans orally exposed to chromium. Chem Biol Interact 204(1):13-27; doi: 10.1016/j.cbi.2013.04.003 . PMID: 23603453.
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Topics: chromium , modeling , PBPK/PBDE , pharmacokinetics
O’Brien T, Ding H, Suh M , Thompson C , Parsons BL, Harris MA,…, Haws LC , Proctor DM . 2013. Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water. Mutat Res 754(1-2):15-21. doi: 10.1016/j.mrgentox.2013.03.008 . PMID: 23583686.
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Topics: chromium , water
Thompson CM , Proctor DM , Suh M , Haws LC , Kirman CR, Harris MA. 2013. Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans. Crit Rev Toxicol 43(3):244-274; doi: 10.3109/10408444.2013.768596 . PMID: 23445218.
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Topics: chromium , Exposure Assessment , mode of action
Wikoff D , Fitzgerald L, Haws L , Harris M. Health-based framework for evaluating the safety of hydraulic fracturing products. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: chemical safety assessment , Environmental Science
Suh M , Thompson CM , Hixon JG, Harris MA, Kirman CR, Hays S, Haws LC , Proctor DM . Potential involvement of oxidative stress and iron disturbance in the development of oral cavity tumors in rats exposed to hexavalent chromium. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: chromium
Haws L , Hixon G, DeVito M, Walker N, Kuriakose L, Harris M, Birnbaum L, Wikoff D . Development of weighted distributions of relative potency estimates for dioxin-like compounds. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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Topics: dioxin
Thompson CM , Kirman CR, Proctor DM , Suh M ,Hays SM, Haws LC , Harris MA. A chronic oral reference dose for hexavalent chromium. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
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