Publications

Sweeney LM, Coyle JP, Covington TR, Sterner TR, Clewell RA. Rapid dosimetry in a tiered chemical screening process for military personnel-toxicokinetic considerations for a case study with in vitro neurotoxicity. Abstract 3495, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Stemer TR, Covington TR, Cowan DW, Coyle JP, Gearhart JM, LaLonde TJ, Ring CL, Sweeney LM, Wambaugh JF, Wooten AT, Bang AG, Clewell RA. Rapid risk assessment of potential neurotoxicants using non-animal test methods. Abstract 4842, Society of Toxicology 64^th Annual Meeting, Orlando, FL, March 2025.

Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA. 2025. Systematic evaluation of the evidence base on methyl tert-butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224. PMID: 40084233.

East A, Klaren W, Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.

Covington TR, Borghoff SJ, Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

Perry CS, Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698. PMID: 39251127.

Urban JD, Covington TR, Fitch SE, Wikoff DS. Dioxin-like compounds in soils: A pilot survey updating background soil TEQ. Abstract 5147, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. 

Covington TR, Sterner TR. Physiologically-based pharmacokinetic model to predict HFC-134a in exhaled breath following albuterol inhaler use. Poster presented at the 2023 Toxicology and Risk Assessment Conference, Miamisburg, OH, August 25, 2023.

Sterner TR, Covington TR. Complex mixtures: Array modeling of jet fuel components. Poster presented at the Society of Toxicology Annual Meeting, Nashville, TN, March 2023.

Covington TR, Sterner TR. Physiologically-based pharmacokinetic model to predict HFC-134a in exhaled breath following albuterol inhaler use. Poster presented at the Society of Toxicology Annual Meeting, Nashville, TN, March 2023.

Sterner TR, Covington TR, Mattie DR. 2023. Complex mixtures: Array PBPK modeling of jet fuel components. Toxics 11(2):187; doi: 10.3390/toxics11020187. PMID: 36851061.

Pangburn HA, Linakis MW, Chushak YG, Covington TR, McCarthy MJ, Gearhart JM. New approach methodologies informing operational Air Force mission. Presentation at the Society of Toxicology Annual Meeting, virtual event, March 2021.

Covington TR, Gearhart JM. 2020. Sensitivity and Monte Carlo analysis techniques and their use in uncertainty, variability, and population analysis. In: Fisher JW, Gearhart JM, Lin Z (eds), Physiologically Based Pharmacokinetic (PBPK) Modeling, pp. 211–242. Academic Press.

Covington TR, Ott DK, Gearhart JM, Pangburn HA. Simulating a virtual high-performance aircraft pilot using physiologically-based pharmacokinetic modeling. Poster presented at Annual Meeting of the Aerospace Medical Association, Las Vegas, NV, May 2019.

Sterner TR, Covington TR, Merrill EA, Mattie DR. Novel array approach to mixtures model streamlines predictions of cochlea and brain region tissue concentrations from JP-8 inhalation exposure. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Pitts E, Gearhart JM, Covington TR, Duran CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Thermal stress effects on physiologically based pharmacokinetic model for Department of Defense personnel. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Covington TR. Translating an existing physiologically-based pharmacokinetic model for isopropanol from a scalar to an array format. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Covington TR, Ott DK, Gearhart JM, Pangburn HA. A physiologically-based pharmacokinetic model to address physiological changes associated with high-performance aircraft flight. Presentation at the Annual Meeting of the Military Health System Research Symposium, Orlando, FL, August 2018.

Pangburn HA, Jarvis JP, Covington TR, Ott DK, Gearhart JM. The impact of genetics on the pharmacokinetics of chemicals in a U.S. Air Force population. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.

Gearhart JM, Pitts E, Covington TR, Grabinski CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Physiological simulation of thermal and chemical stressors in a United States Air Force population. Presentation at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.