Publication Topic

Zhang L, McHale CM, Greene N, Snyder R, Rich IN, Aardema MJ, Roy S, Pfuhler S, et al. 2014. Emerging approaches in predictive toxicology. Environ Mol Mutagen 55(9):679-88; doi: 10.1002/em.21885. PMID: 25044351.

Christian WV, Oliver LD, Paustenbach DJ, Kreider ML, Finley BL. 2014. Toxicology-based cancer causation analysis of CoCr-containing hip implants: A quantitative assessment of genotoxicity and tumorigenicity studies. J Appl Toxicol 34(9):939–967; doi: 10.1002/jat.3039.

Sutter A, Amberg A, Boyer S, Brigo A, Contrera JF, Custer LL, Dobo KL,…, Greene N, et al. 2013. Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities. Regul Toxicol Pharmacol 67(1):39-52; doi: 10.1016/j.yrtph.2013.05.001. PMID: 23669331.

Urban JD, Carakostas MC, Brusick DJ. 2013. Steviol glycoside safety: Is the genotoxicity database sufficient? Food Chem Toxicol 51(Jan):386-390; doi: 10.1016/j.fct.2012.10.016. PMID: 23103588.

Naven RT, Greene N, Williams RV. 2012. Latest advances in computational genotoxicity prediction. Exp Opin Drug Metabol 8(12):1579-87; doi: 10.1517/17425255.2012.724059. PMID: 22998164.

Bylsma LC. Characterization of diet and dietary exposures to genotoxic compounds in pregnant women of Mexico City. Presented at the University of Michigan School of Public Health (UMSPH) Epidemiology Poster Session and UM Student Global Health Day, Ann Arbor, MI, November 2012.

Schmitt D, Tran N, Peach J, Bauter M, Marone P. 2012. Toxicologic evaluation of DHA-rich algal oil: Genotoxicity, acute and subchronic toxicity in rats. Food Chem Toxicol 50(10):3567–3576; doi: 10.1016/j.fct.2012.07.054. PMID: 22898615.

Thompson CM, Hixon JG, Proctor DM, Haws LC, Suh M, Urban JD, Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1):68-76; doi: 10.1016/j.yrtph.2012.05.019. PMID: 22705708.

Thompson CM, Fedorov Y, Brown DD, Suh M, Proctor DM, Kuriakose L, Haws L, Harris MA. 2012. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS One 7(8):e42720; doi: 10.1371/journal.pone.0042720. PMID: 22905163.

Dobo KL, Greene N, Fred C, Glowienke S, Harvey JS, Hasselgren C, Jolly R, Kenyon MO, et al. 2012. In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey. Regul Toxicol Pharmacol 62(3):449-455; doi: 10.1016/j.yrtph.2012.01.007. PMID: 22321701.

Harris MA, Thompson CM, Wolf JC, Fedorov Y, Hixon JG, Proctor DM, Suh M, Haws LC. Assessment of genotoxic potential of Cr(VI) in the intestine via in vivo intestinal micronucleus assay and in vitro high content analysis in differentiated and undifferentiated caco-2. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Thompson CM, Hixon JG, Kopec AK, Harris MA, Proctor DM, Haws LC. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Urban J, Rowlands JC, Budinsky R, Dombkowski A, Thompson CM, Thomas RS. A genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Robison TW. 2011. Dealing with positive in vitro mammalian cell genotoxicity assays. Inter Drug Discovery 6(5):40-43.

Tichomirowa MA, Bariler A, Daly AF, Jaffrain-Rea M-L, Ronchi CL, Yaneva M, Urban JD, Petrossians P, et al. 2011. High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas. Eur J Endocrinol 165(4):509-515; doi: 10.1530/EJE-11-0304. PMID: 21753072.

Grace CE, Kim SJ, Rogers JM. 2011. Maternal influences on epigenetic programming of the developing hypothalamic-pituitary-adrenal axis. Birth Defects Res A 91(8):797–805; doi: 10.1002/bdra.20824. PMID: 21656659.

Robison TW. Genotoxic impurity guidance – Current experiences, FDA perspective. USP Annual Meeting, New Orleans, LA, December 2010.

Chen F, Smith R, Gu YZ, Collins ND, Nioi P. 2010. Toxicoepigenetic alteration of the Kidney Injury Molecule 1 gene in gentamicin-exposed rat kidney. Toxicol Sci 117(2):375–380; doi: 10.1093/toxsci/kfq202. PMID: 20660082.

Robison TW. Dealing with positive in vitro mammalian cell genotoxicity assays. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.

Robison TW. Dealing with genotoxic impurities from a regulatory perspective. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.