Publication Topic

Thompson CM, Hixon JG, Kopec AK, Harris MA, Proctor DM, Haws LC. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

Robison TW. 2011. Dealing with positive in vitro mammalian cell genotoxicity assays. Inter Drug Discovery 6(5):40-43.

Robison TW. Genotoxic impurity guidance – Current experiences, FDA perspective. USP Annual Meeting, New Orleans, LA, December 2010.

Robison TW. Dealing with positive in vitro mammalian cell genotoxicity assays. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.

Robison TW. Dealing with genotoxic impurities from a regulatory perspective. IQPC Genotoxicity and Carcinogenicity Testing 2010 Conference, London, UK, October 2010.

Robison TW. Assessing genotoxic impurities. DIA Meeting (Early drug development: Navigating the treacherous rapids). Bethesda, MD, October 2010

Waters MD, Jackson MA, Lea IA. 2010. Characterizing and predicting carcinogenicity and mode-of-action using conventional and toxicogenomics methods. Mutat Res 705(3):184–200; doi: 10.1016/j.mrrev.2010.04.005.

Elespuru RK, Agarwal R, Atrakchi A, Bigger CAH, Heflich RH, Jagannath D, Levy DD…Robison TW, et al. 2009. Current and future application of genetic toxicity assays: The role and value of in vitro mammalian assays. Toxicol Sci 109(2):172-179; doi: 10.1093/toxsci/kfp067.

Davis II JW, Goodsaid FM, Bral CM, Mandakas G, Obert LA, Garner CE, Collins N, et al. 2004. Quantitative gene expression analysis in a nonhuman primate model of antibiotic-induced nephrotoxicity. Toxicol Appl Pharmacol 20(1):16–26; doi: 10.1016/j.taap.2004.02.001. PMID: 15451304.

Peters JM, Aoyama T, Burns AM, Gonzalez FJ. 2003. Bezafibrate is a dual ligand for PPARalpha and PPARbeta: Studies using null mice. Biochim Biophys Acta 1632(1-3):80-89; doi: 10.1016/s1388-1981(03)00065-9. PMID: 12782154.

Morrissey RE, Horvath C, Snyder EA, Patrick J, Collins N, Evans E, MacDonald JS. 2002. Porcine toxicology studies of SCH 58500, an adenoviral vector for the p53 gene. Toxicol Sci 65(2):256–265; doi: 10.1093/toxsci/65.2.256. PMID: 11812930.

Albrecht B, Collins ND, Burniston MT, Nisbet JW, Ratner L, Green PL, Lairmore MD. 2000. Human T-lymphotropic virus type 1 open reading frame I p12I is required for efficient viral infectivity in primary lymphocytes. J Virol 74(21):9828–9835; doi: 10.1128/jvi.74.21.9828-9835.2000. PMID: 11024109.

Collins ND, D’Souza C, Albrecht B, Robek MD, Ratner L, Ding W, Green PL, Lairmore MD. 1999. Proliferation response to interleukin-2 and Jak/Stat activation of T cells immortalized by human T-cell lymphotropic virus type 1 is independent of open reading frame I expression. J Virol 73(11):9642–9649; doi:  10.1128/JVI.73.11.9642-9649.1999. PMID: 10516077.

Collins ND, LeRoy BE, Vap L. 1998. Artifactually increased serum bicarbonate values in two horses and a calf with severe muscle disease. Vet Clin Pathol 27(3):85–90; doi: 10.1111/j.1939-165x.1998.tb01025.x. PMID: 12075544.

Collins ND, Newbound GC, Ratner L, Lairmore MD. 1996. In vitro CD4+ lymphocyte transformation and infection in a rabbit model with a molecular clone of human T-cell lymphotropic virus type 1. J Virol 70(10):7241–7246; doi: 10.1128/JVI.70.10.7241-7246.1996. PMID: 8794375.

Schmitt D, Frankos V, Westland J, Zoetis T. 1991. Toxicologic evaluation of cellulon fiber; Genotoxicity, pyrogenicity, acute and subchronic toxicity. J Am Coll Toxicol 10(5):541–554; doi: 10.3109/109158191090786.