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2020 (8 POSTS)

Bylsma LC, Dean R, Lowe K, Sangare L, Alexander D, Fryzek J. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis of patient and study characteristics. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

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Henderson RG, Franzen A, Franke K, Payne L, Schmitt D, Wikoff D. Creating a literature database for cannabidiol (CBD): Systematic evidence mapping. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.

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2019 (13 POSTS)

Wikoff DS, Chappell GA, Fitch S, Doepker CL, Borghoff SJ. 2019. Lack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135:110866.

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Chappell GA, Borghoff SJ, Pham L, Doepker CL, Wikoff DS. 2019. Lack of potential carcinogenicity for sucralose — Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135:110898.

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Bylsma LC, Dean R, Lowe K, Sangaré L, Alexander DD, Fryzek JP. 2019. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta‐analysis of patient and study characteristics. Cancer Med 8(12):5800–5809.

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Fitch S, Goyak K, Green M, Grimm F, Wikoff D. 2019. Estrogen-mediated outcomes for alkylphenols via an adverse outcome pathway (AOP) construct. Open Science Framework, August.

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Fitch S, van de Ligt J, Payne L, Doepker C, Kleinman R, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2019. Systematic map protocol: A systematic map of the use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS). Open Science Framework.

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Wikoff D, Erranguntla N, Lewis J, Foreman J. A fit-for-purpose framework for use of systematic methods in risk assessment. Poster at Evidence Integration in Chemical Assessments: Challenges Faced in Developing and Communicating Human Health Effect Conclusions. National Academies of Sciences, Engineering, and Medicine, Washington, DC, June 2019.

Bylsma LC, Levin-Sparenberg E, Lowe K, Sangare L, Fryzek J, Alexander DD. Prevalence of KRAS, NRAS, and BRAF gene mutations in metastatic colorectal cancer (MCRC) patients: A systematic literature review and meta-analysis. Poster presented as part of a Spotlight Poster Session at the International Society for Pharmacoepidemiology, August 2019, Philadelphia, PA.

Bylsma LC, Dean R, Lowe K, Sangare L, Alexander D, Fryzek J. The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis. Poster presented at the International Society for Pharmacoepidemiology, August 2019, Philadelphia, PA.

Wikoff D. Rigor and resources for systematic reviews in toxicology: Case study applications in food safety, consumer product safety, and environmental health risk assessment. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

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Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

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Suh M, Wikoff D, Lipworth L, Goodman M, Fitch S, Mittal L, Ring C, Proctor D. 2019. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Crit Rev Toxicol [ePub ahead of print]: doi: 10.1080/10408444.2019.1578730.

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Wikoff D, Fitch SE, Payne L, Doepker C, van de Ligt J. 2019. Systematic map: Use of the acceptable daily intake (ADI) values in nutrition research studies that consider the safety of low-calorie sweeteners. Open Science Framework.

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Wikoff DS, Rager JE, Chappell GA, Fitch S, Haws L, Borghoff SJ. 2019. A framework for systematic evaluation and quantitative integration of mechanistic data in assessments of potential human carcinogens. Toxicol Sci 167(2):322-335.

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2018 (11 POSTS)

Wikoff D. Problem formulation: Lessons and tools from practical applications involving systematic review of mechanistic data. Presented at Strategies and Tools for Conducting Systematic Reviews of Mechanistic Data to Support Chemical Assessments, National Academies of Sciences, Engineering, and Medicine. Washington, D.C., December 2018.

Urban J, Wikoff D, Haws L, Fitch S, Ring C, Thompson C, Suh M. 2018. Systematic review protocol: Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count. Zenodo. http://doi.org/10.5281/zenodo.1636357.

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Tsaioun K, Dirven H, Beck Færden K, Wikoff D, Ram R, Kleinstreuer N, McCormack A, Wright R, Vist GE, Fitch S. 2018. Systematic reviews of the hepatotoxic effects of specified compounds/drugs as observed in humans and experimental animals (rats, mice, dogs and non-human primates). PROSPERO CRD42018112353.

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Suh M, Wikoff D, Harvey S, Mittal L, Lipworth L, Goodman M, Goodmanson A, Ring C, Rohr A, Proctor D. Hexavalent chromium and stomach cancer: A systematic review and meta-analysis. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.

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Urban JD, Harvey S, Haws LC, Wikoff D. Assessment of study quality (risk of bias) in understanding the relationship between congenital heart defects (CHDs) and exposures to trichloroethylene (TCE). Society of Toxicology Annual Meeting. March 11–15, 2018. San Antonio, TX.

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