Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M, Gray F, Jensen K, Dahlgren M, Pelletier R, Dingley K, et al. 2025. In silico enabled discovery of KAI-11101, a preclinical DLK inhibitor for the treatment of neurodegenerative disease and neuronal injury. J Med Chem 68(3):2720-2741; doi: 10.1021/acs.jmedchem.4c02074 . PMID: 39670820.
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Publication: Manuscripts
/ Topics: neurodegenerative disease
Borghoff SJ, Rivera B, Fitch S, Buerger AN, Choksi N, Franzen A, Vincent MJ, Covington T, Bus J, Rushton E, Lea IA . 2025. Systematic evaluation of the evidence base on methyl tert -butyl ether supporting a lack of concern for carcinogenic hazard in human based on animal cancer studies and mechanistic data. Curr Res Toxicol 8:100224; doi: 10.1016/j.crtox.2025.100224 . PMID: 40084233.
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Publication: Manuscripts
/ Topics: Cancer , carcinogens , MTBE , risk assessment
Rogers JM, Buerger AN , Heintz MM , Palermo CM, Haws LC, Lea IA . 2025. Evaluation of a hypothesized Sertoli cell-based adverse outcome pathway for effects of diisononyl phthalate on the developing testis. Curr Res Toxicol 8:100219; doi: 10.1016/j.crtox.2025.100219 . PMID: 40123861.
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Publication: Manuscripts
/ Topics: phthalates
Lea IA , Buerger AN , Feifarek D, Mihalchik A, Heintz MM, Haws LC , Nyambego H, Goyak K, Palermo C, Borghoff SJ . 2025. Evaluation of the endocrine disrupting potential of Di-isononyl phthalate. Curr Res Toxicol 8:100220; doi: 10.1016/j.crtox.2025.100220 . PMID: 40092461.
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Publication: Manuscripts
/ Topics: phthalates
Kennedy SB, Heintz MM, Klaren WD, Wikoff DS, Haws LC, Fitch SE . 2025. An integrated ecotoxicological study reliability framework for use in toxicity value development. Environ Tox Chem 44(4):1142-1153; doi: 10.1093/etojnl/vgaf030 . PMID: 39873747.
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/ Topics: Ecology , risk assessment , Toxicology
Schaefer HR, Vincent MJ , Burns CJ, Lange SS. 2025. Increasing the utility of epidemiologic studies as key evidence in chemical risk assessment. Toxicol Sci 203(2):166-170; doi: 10.1093/toxsci/kfae134 . PMID: 39657235.
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Publication: Manuscripts
/ Topics: Epidemiology , risk assessment
Zilber D, Messier KP, House J, Parham F, Auerbach SS, Wheeler MW . 2025. Bayesian gene set benchmark dose estimation for “omic” responses. Bioinformatics 41(1):btaf008; doi: 10.1093/bioinformatics/btaf008 . PMCID: PMC11783320.
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Publication: Manuscripts
/ Topics: benchmark dose estimation (BMD) , Toxicology , transcriptomics
Rana Z, Frankenfeld CL , Kennedy E, Bertoldi J, de Jonge E, Cheskin L. 2025. Food sources of energy and nutrients among US college students: The Health Starts Here cohort study. J Am Coll Health 73(1):301-310; doi: 10.1080/07448481.2023.2220397 . PMID: 37290009.
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Publication: Manuscripts
/ Topics: Epidemiology , Food science
Lipworth L, Panko JM , Allen BC, Mumma MT, Jiang X , Vincent MJ , Bare JL , Antonijevic T, Vivanco SN , Marano DE, Suh M , Cohen S, Mittal L , Proctor DM . 2025. Lung cancer mortality among aircraft manufacturing workers with long-term, low-level, hexavalent chromium exposure. J Occup Environ Hyg 22(3):214-227 ; doi: 10.1080/15459624.2024.2439817 . PMID: 39773194.
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