2025 (30 POSTS)
Chen K, Price S, Finley B . An evaluation of the biokinetics of bone lead levels in children following tap water exposure using the All Ages Lead Model (AALM). Abstract 4079, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: Exposure Assessment , lead
Buerger AN, Vincent MJ, Fitch S , Rushton EK, Borghoff SJ . Evaluation of potential obesogenicity through a mode of action approach: A case study with MTBE. Abstract 3928, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: MTBE
Brown L . Integrating new approach methodologies to inform sustainable chemical decisions. Abstract 1156, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: Product Life Cycle , risk assessment , sustainability
Borghoff SJ, Rivera BN, Fitch S, Buerger A, Choksi N, Franzen A , Bus J, Rushton EK, Lea I . Systematic evaluation of the evidence base on methyl tert-butyl ether for carcinogenic potential in humans; Low concern based on animal cancer studies and mechanistic data. Abstract 4702, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: carcinogens , MTBE
Massarsky A, Buerger AN , O’Neill HC, Gaffner J, Mucs D, Baskerville-Abraham I, Maier A. Derivation of Maximum Acceptable Group Levels (MAGLs) for ionones and related compounds. Abstract 4764, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: Food science , ionones , risk assessment , Toxicology
Bogar L, Yale K , Allen L, Burns A . Airborne silica from bentonite clay cat litter: An evaluation of potential non-occupational exposure and respiratory health risks. Abstract 4760, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025 .
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Topics: Exposure Assessment , health effects , silica
Jacobellis M , Garcia M, Bain L, Pearce J, Hunt K, Baldwin W. Disruption of energy homeostasis by chemical mixtures containing persistent pollutants in HepG2 and C2C12 cells. Abstract 4564, Society of Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: chemical mixtures , persistent pollutants , Toxicology
Reynolds JI , Yelleti A, Johnson BP. Bridging data gaps in sonic hedgehog signaling: A novel microphysiological model approach. Abstract 3234, Society for Toxicology 64th Annual Meeting, Orlando, FL, March 2025.
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Topics: Adverse outcome pathways (AOPs) , modeling , Sonic Hedgehog (SHH) signaling
Wikoff D . Use cases of strategic application of ML/AI in the risk assessment process. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Topics: Food science , risk assessment
Wikoff D . Pragmatic solutions for better using evidence-based methods to integrate observational data in food safety assessments. Toxicology Forum 2025 Winter Meeting, Raleigh, NC, February 2025.
Topics: Food science , risk assessment
2024 (57 POSTS)
Olaye A, Bean K, Velikanova R, Wolters S, Miller B, Jensen I, Pang F. Cost-effectiveness of atidarsagene autotemcel (ARSA-CEL) gene therapy for treating metachromatic leukodystrophy (MLD) in Ireland, Belgium, and the Netherlands as a part of the Beneluxa Initiative. Abstract EE693 . ISPOR Europe 2024, November 2024.
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Topics: Metachromatic leukodystrophy (MLD)
Haselkorn T, Hughes W, Lennox A, Schara-Schmidt U, Roca A, Miller B, Jensen I , et al. Real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in the United Kingdom (UK), Germany, and Spain. ISPOR EU 2024 (Top 5% Finalist).
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Topics: XLMTM
Haselkorn T, Roca A, Miller B, Jensen I , Solomon F, Sanchez-de la Rosa R, Picart JM, Nascimento A. A real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in Spain. Presented at LXXVI Reunion Annual de la Sociedad Espanola de Nurologica, 19–23 November 2024.
Topics: XLMTM
Gauthier A, Bare J, Kramer M . Tools and tips for exposure assessment throughout the product development life cycle. Education session, PSX 2024, Annual Conference of the Product Stewardship Society, Denver, CO, October 2024.
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Topics: Exposure Assessment , Product Life Cycle , Product Stewardship
Kelsh M , Bylsma LC, Jiang X, Movva N , Sacks NC . To be an orphan disease or not to be: An evaluation of prevalence estimates for cancers near the orphan status threshold and implications for orphan drug planning. International Society for Pharmacoepidemiology, 40th Annual Meeting, Berlin, Germany, August 2024.
Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Suh M, Mittal L, Brorby G, Pastula S, Vincent M, Proctor D . Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
East A, Klaren W, Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.
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Topics: Air Quality , Epidemiology
Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S , et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: Epidemiology , Toxicology
Covington TR , Borghoff SJ , Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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Topics: modeling
Lea IA , Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.
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