2017 (47 POSTS)
Greene T, Rogers S, Franzen A , Gentry R. 2017. A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. Crit Rev Toxicol 47(2):98–120. DOI:10.1080/10408444.2016.1236071.
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Topics: Toxicology
Franzen A , Greene T, Van Landingham C, Gentry R. 2017. Toxicology of octamethylcyclotetrasiloxane (D4). Toxicol Lett 279 Suppl 1:2–22. DOI:10.1016/j.toxlet.2017.06.007.
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Topics: Toxicology
Gentry R, Franzen A , Van Landingham C, Greene T, Plotzke K. 2017. A global human health risk assessment for octamethylcyclotetrasiloxane (D4). Regul Toxicol Pharmacol 279(Sup 1):23-41; doi: 10.1016/j.toxlet.2017.05.019 .
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Topics: risk assessment , Toxicology
Kirman CR, Suh M, Proctor DM , Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325(15 June):9-17; doi: 10.1016/j.taap.2017.03.023 .
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Topics: Cr(VI) MOA Study , Hexavalent Chromium , modeling , PBPK , pharmacokinetics , Toxicology
Jackson MA, Yang L, Lea I , Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535; doi: 10.1002/em.22114 .
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Topics: Toxicology
Mease K , Kimzey A , Lansita J. 2017. Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design. Curr Opin Toxicol 4(June):1–15; doi: 10.1016/j.cotox.2017.03.005 .
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Topics: biomarkers
Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N , et al. 2017. Multivariate models for prediction of human skin sensitization hazard. J Appl Toxicol 37:347–360; doi: 10.1002/jat.3366 .
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Topics: Toxicology
Lea IA , Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971; doi: 10.1093/nar/gkw1077 .
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Topics: Toxicology
Haber LT, Bates HK, Allen BC, Vincent MJ , Oller AR. 2017. Derivation of an oral toxicity reference value for nickel. Regul Toxicol Pharmacol 87(S1–S18), doi: 10.1016/j.yrtph.2017.03.011.
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Topics: Toxicology
Vincent MJ , Parker A, Maier A. 2017. Cleaning and asthma: A systematic review and approach for effective safety assessment. Regul Toxicol Pharmacol 90:231–243, doi: 10.1016/j.yrtph.2017.09.013.
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Topics: Systematic Review , Toxicology
Vincent MJ , Bernstein JA, Basketter D, LaKind JS, Dotson GS, Maier A. 2017. Chemical-induced asthma and the role of clinical, toxicological, exposure and epidemiological research in regulatory and hazard characterization approaches. Regul Toxicol Pharmacol 90(Nov):126–132; doi: 10.1016/j.yrtph.2017.08.018 .
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Topics: Epidemiology , Exposure Assessment , Toxicology
Morgan SJ, Couch J, Guzzie-Peck P, Keller DA , Kemper R, Otieno MA, Schulingkamp RJ, Jones TW. 2017. Regulatory forum opinion piece: Use and utility of animal models of disease for nonclinical safety assessment: A pharmaceutical industry survey. Toxicol Pathol 45(3):372–380, doi: 10.1177/0192623317701004.
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Topics: Toxicology
Prescott JS, Andrews PA, Baker RW, Bogdanffy MS, Fields FO, Keller DA , Lapadula DM, Mahoney NM, Paul DE, Platz SJ, Reese DM, Stoch SA, DeGeorge JJ. 2017. Evaluation of therapeutics for advanced-stage heart failure and other severely-debilitating or life-threatening diseases. Clin Pharmacol Ther 102(2):219–227, doi: 10.1002/cpt.730.
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Topics: Toxicology
Ewart L, Fabre K, Chakilam A, Dragan Y, Duignan DB, Eswaraka J, Gan J, Guzzie-Peck P, Otieno M, Jeong CG, Keller DA , de Morais SM, Phillips JA, Proctor W, Sura R, Van Vleet T, Watson D, Will Y, Tagle D, Berridge B. 2017. Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective. Exp Biol Med (Maywood) 242(16):1579–1585, doi: 10.1177/1535370217715441.
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Topics: Toxicology
Monticello TM, Jones TW, Dambach DM, Potter DM, Bolt MW, Liu M, Keller DA , Hart TK, Kadambi VJ. 2017. Current nonclinical testing paradigm enables safe entry to first-in-human clinical trials: The IQ consortium nonclinical to clinical translational database. Toxicol Appl Pharmacol 334:100–109, doi: 10.1016/j.taap.2017.09.006 .
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Topics: Toxicology
Frankenfeld CL . 2017. Cardiometabolic risk and gut microbial phytoestrogen metabolite phenotypes. Mol Nutr Food Res 61(1):1500900; doi: 10.1002/mnfr.201500900 .
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Topics: Epidemiology
Miller LM, Lampe JW, Newton KM, Gundersen G, Fuller S, Reed SD, Frankenfeld CL . 2017. Being overweight or obese is associated with harboring a gut microbial community not capable of metabolizing the soy isoflavone daidzein to O-desmethylangolensin in soy-consuming peri- and post-menopausal women. Maturitas 99:37–42, https://doi.org/10.1016/j.maturitas.2017.02.006 .
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