2021 (95 POSTS)
Giblin KA, Basili D, Afzal AM, Rosenbrier-Ribeiro L, Greene N , Barrett I, Hughes SJ, Bender A. 2021. New associations between drug-induced adverse events in animal models and humans reveal novel candidate safety targets. Chem Res Toxicol 34(2):438-451; doi: 10.1021/acs.chemrestox.0c00311 . PMID: 33338378.
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Topics: drug development
Dake MD, Fanelli F, Lottes AE, O’Leary EE, Reichert H , Jiang X , Fu W, Iida O, et al. 2021. Prediction model for freedom from TLR from a multi-study analysis of long-term results with the Zilver PTX drug-eluting peripheral stent. Cardiovasc Intervent Radiol 44(2):196-206; doi: 10.1007/s00270-020-02648-6 . PMID: 33025243.
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Topics: drug interactions , modeling
Wikoff DS , Urban JD , Ring C, Britt J , Fitch S , Haws LC . 2021. Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression. Toxicol Sci 179(2):162-182; doi: 10.1093/toxsci/kfaa171 .
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Topics: dioxin , Systematic Review
Chappell GA, Heintz MM , Haws LC . 2021. Transcriptomic analyses of livers from mice exposed to 1,4-dioxane for up to 90 days to assess potential mode(s) of action underlying liver tumor development. Curr Res Toxicol 2:30–41; doi: 10.1016/j.crtox.2021.01.003 .
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Topics: transcriptomics , VOCs
Fan TH, Hassett CE, Migdady I, Price C , Choi CW, Katzan I, et al. 2021. How are we monitoring brain injuries in patients with left ventricular assist device? A systematic review of literature. ASAIO Journal (Am Soc Artif Intern Organs: 1992) 67(2)-149–156; https://doi.org/10.1097/MAT.0000000000001204 .
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Topics: Systematic Review
Shukla A, Ahmed OG, Orlov CP, Price C , Mukherjee D, Choby G, et al. 2021. Quality-of-life instruments in endoscopic endonasal skull base surgery-A practical systematic review. Int Forum Allergy Rhinol 11(8):1264–1268; https://doi.org/10.1002/alr.22783 .
Topics: Systematic Review
Slavin M, Li H, Khatri M, Frankenfeld C . 2021. Dietary magnesium and migraine in adults: A cross-sectional analysis of the National Health and Nutrition Examination Survey, 2001-2004. Headache 61(2):276–286; doi: 10.1111/head.14065 . PMID: 33503279.
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Topics: Epidemiology , magnesium , NHANES , nutrition
Frankenfeld CL . 2021. Reduced rank regression: Illustration of an important tool in the evaluation of dietary patterns and chronic disease risk. J Nutr 151:3269–3270, https://doi.org/10.1093/jn/nxab331 .
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Topics: Epidemiology
Elbeddini A, Tayefehchamani Y, Davey M, Gallinger J, Hooda N , Aly A, Erickson D, Lee S. 2021. Fournier’s gangrene with dapagliflozin in a rural hospital: A case report. BMJ Case Rep 14(2):e237784; doi: 10.1136/bcr-2020-237784 . PMID: 33526523.
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Topics: diabetes , drug interactions
Frankenfeld CL . 2021. Fecal bacteria as an addition to the lineup of objective dietary biomarkers. J Nutr
151(2):273–274; doi: 10.1093/jn/nxaa359 . PMID: 33326570.
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Topics: biomarkers , nutrition
Thompson CM , Bhat VS, Brorby GP , Haws LC . 2021. Development of updated RfD and RfC values for medium carbon range aromatic and aliphatic total petroleum hydrocarbon fractions. J Air Waste Manag Assoc 71(12):1555–1567; doi: 10.1080/10962247.2021.1974123 . PMID: 34469276.
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Topics: Air Quality , Exposure Assessment , petroleum
Chappell GA, Wikoff DS , Thompson CM . 2021. Assessment of mechanistic data for hexavalent chromium-induced rodent intestinal cancer using the key characteristics of carcinogens. Toxicol Sci 180(1):38–50; doi: 10.1093/toxsci/kfaa187 . PMID: 33404626.
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Topics: Cancer , chromium
Brozek JL, Canelo-Aybar C, Akl EA, Bowen JM, Bucher J, Chiu WA, Cronin M, Djulbegovic B,…, Patlewicz G , et al. 2021. GRADE Guidelines 30: The GRADE approach to assessing the certainty of modeled evidence—An overview in the context of health decision-making. J Clin Epidemiol 129(Jan):138-150; doi: 101016/j.jclinepi.2020.09.018 . PMID: 32980429.
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Topics: modeling
Rovida C, Escher SE, Herzler M, Bennekou SH, Kamp H, Kroese DE, Maslankiewicz L, Moné MJ, Patlewicz G , et al. 2021. NAM-supported read-across: From case studies to regulatory guidance in safety assessment. ALTEX 38(1):140-150; doi: 10.14573/altex.2010062 . PMID: 33452529.
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Topics: NAMs
Frankenfeld CL , Hakes JK, Leslie TF. 2021. All-cause mortality and residential racial and ethnic segregation and composition as experienced differently by individual-level race, ethnicity, and gender: Mortality disparities in American communities data. Ann Epidemiol 65(Jan):38-45; doi: 10.1016/j.annepidem.2021.10.008 . PMID: 34757014.
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Topics: community health , Epidemiology , risk assessment
Wheeler MW , Westerhout J, Baumert JL, Remington BC. 2021. Bayesian stacked parametric survival with frailty components and interval‐censored failure times: An application to food allergy risk. Risk Anal 41(1):56-66; doi: 10.1111/risa.13585 . PMCID: PMC7894991.
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Topics: Bayesian modeling , Food science , risk analysis
Marvel SW, House JS, Wheeler MW , Song K, Zhou Y-H, Wright FA, Chiu WA, Rusyn I, Motsinger-Reif A, Reif DM. 2021. The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine learning. Environ Health Perspect 129(1):017701; doi: 10.1289/EHP8690 . PMCID: PMC7430608
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Topics: COVID-19 , modeling
2020 (92 POSTS)
Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D , Atillasoy E. 2020. Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen. Regul Toxicol Pharmacol 118(Dec):104788; doi: 10.1016/j.yrtph.2020.104788 . PMID: 33153971.
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Topics: carcinogens , modeling
Cohen SS, Roger VL, Weston SA, Jiang R, Movva N , Yusuf AA, Chamberlain AM. 2020. Evaluation of claims-based computable phenotypes to identify heart failure patients with preserved ejection fraction. Pharmacol Res Persp 8(6):e00676; doi: 10.1002/prp2.676 . PMID: 33124771.
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