2017 (62 POSTS)
Wang Y, Villalta PW, Peng L, Dingley KH , Malfatti MA, Turteltaub KW, Turesky RJ. 2017. Mass spectrometric characterization of an acid-labile adduct formed with 2-amino-1-methyl-phenylimidazo[4,5-b]pyridine and albumin in humans. Chem Res Toxicol 30(2):705–714; doi: 10.1021/acs.chemrestox.6b00426 . PMID: 27984695.
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Topics: carcinogens
Harper BH, Wang L, Zhu C, Kar NF, Li B, Moyes CR, … Dingley K , et al. 2017. Investigation of piperazine benzamides as human β3 adrenergic receptor agonists for the treatment of overactive bladder. Bioorg Med Chem Lett 27(4):1094–1098; doi: 10.1016/j.bmcl.2016.12.033 . PMID: 28089699.
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Topics: pharmacokinetics
Zhu C, Wang L, Zhu Y, Guo ZZ, Liu P, Hu Z, … Dingley KH , et al. 2017. Discovery of phenyl acetamides as potent and selective GPR119 agonists. Bioorg Med Chem Lett 27(5):1124–1128; doi: 10.1016/j.bmcl.2017.01.091 . PMID: 28185720.
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Topics: pharmacokinetics
Pandalai SP, Wheeler MW , Lu M-L. 2017. Non-chemical risk assessment for lifting and low back pain based on Bayesian threshold models. Saf Health Work 8(2):206-11; doi: 10.1016/j.shaw.2016.10.001 . PMID: 28593078.
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Topics: Bayesian modeling , Occupational , risk assessment
Haber LT, Bates HK, Allen BC, Vincent MJ , Oller AR. 2017. Derivation of an oral toxicity reference value for nickel. Regul Toxicol Pharmacol 87(S1):S1-S18; doi: 10.1016/j.yrtph.2017.03.011 . PMID: 28300623.
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Topics: nickel
Finley B , Scott PK, Glynn ME, Paustenbach D, Donovan E, Thuett KA. 2017. Chromium speciation in the blood of metal-on-metal hip implant patients. Environ Toxicol Chem 99(1):48–64; doi: 10.1080/02772248.2016.1148904 .
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Topics: chromium , Exposure Assessment , Metals
Fung ES, Monnot A, Kovochich M, Unice KM, Tvermoes BE, Galbraith D, Finley BL , Paustenbach DJ. 2017. Characteristics of cobalt-related cardiomyopathy in metal hip implant patients: An evaluation of 15 published reports. Cardiovascul Toxicol 18(3):206–220; doi: 10.1007/s12012-017-9433-z . PMID: 29188590.
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Topics: cobalt
Mullins M, Jiang X , Bylsma LC , Fryzek JP, Reichert H , Chen EC, Kummar S, Rosenthal A. 2017. Cold agglutinin disease burden: A longitudinal analysis of anemia, medications, transfusions, and healthcare utilization. Blood Adv 1(13):839-848; doi: 10.1182/bloodadvances.2017004390 . PMID: 29296728.
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Topics: Cancer , Epidemiology
Borghoff SJ , Ring C, Banton M, Leavens TL. 2017. Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to a2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes. J Appl Toxicol 37(5):621-640; doi: 10.1002/jat.3412 . PMID: 27885692.
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Topics: modeling , pharmacokinetics
Miller LM, Lampe JW, Newton KM, Gundersen G, Fuller S, Reed SD, Frankenfeld CL . 2017. Being overweight or obese is associated with harboring a gut microbial community not capable of metabolizing the soy isoflavone daidzein to O-desmethylangolensin in soy-consuming peri- and post-menopausal women. Maturitas 99(May):37–42; doi: 10.1016/j.maturitas.2017.02.006 . PMID: 28364866.
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Topics: Epidemiology , nutrition
Greene T, Rogers S, Franzen A , Gentry R. 2017. A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. Crit Rev Toxicol 47(2):98–120; doi: 10.1080/10408444.2016.1236071 . PMID: 27834107.
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Topics: benchmark dose estimation (BMD) , Exposure Assessment , food additives , mode of action
Fitzpatrick J, Patlewicz G . 2017. Application of IATA – A case study in evaluating the global and local performance of a Bayesian network model for skin sensitization. SAR QSAR Environ Res 28(4):297-310; doi: 10.1080/1062936X.2017.1311941 . PMID: 28423913.
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Topics: Adverse outcome pathways (AOPs) , Bayesian modeling
Wirbisky SE , Freeman JL. 2017. Atrazine exposure elicits copy number alterations in the zebrafish genome. Comp Biochem Physiol C Toxicol Pharmacol 194(Apr):1–8; doi: 10.1016/j.cbpc.2017.01.003 . PMID: 28111253.
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Topics: atrazine
Meddings J, Reichert H , Green MT, Safdar N, Krein SL, Olmsted RN, Watson SR, Edson B, et al. 2017. Evaluation of the association between catheter‐associated infections and measures of safety culture: Results of two national collaboratives. BMJ Qual Saf 26(3):226-235; doi: 10.1136/bmjqs-2015-005012 . PMID: 27222593.
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Topics: Health Economics and Outcomes Research (HEOR) , safety assessment
Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N , et al. 2017. Multivariate models for prediction of human skin sensitization hazard. J Appl Toxicol 37(3):347–360; doi: 10.1002/jat.3366 . PMID: 27480324.
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Topics: modeling
Finley BL , Benson SM, Marsh GM. 2017. Cosmetic talc as a risk factor for pleural mesothelioma: A weight of evidence evaluation of the epidemiology. Inhal Toxicol 29(4):179–185; doi: 10.1080/08958378.2017.1336187 . PMID: 28651470.
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Topics: Cancer , Epidemiology , talc
Friedman D, Fryzek J, Jiang X , Bloomfield A, Ambrose CS, Wong PC. 2017. Respiratory syncytial virus hospitalization risk in the second year of life by specific congenital heart disease diagnoses. PLoS One 12(3):e0172512; doi: 10.1371/journal.pone.0172512 . PMID: 28253361.
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Topics: Epidemiology , Health Economics and Outcomes Research (HEOR)
Alexander DD, Miller PE, van Elswyk M, Kuratko C, Bylsma L. 2017. A meta-analysis of randomized controlled trials and prospective cohort studies of eicosapentaenoic and docosahexaenoic long chain omega-3 fatty acids and coronary heart disease risk. Mayo Clinic Proceedings 92(1):15-29; doi: 10.1016/j.mayocp.2016.10.018 . PMID: 28062061.
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Topics: Epidemiology , meta-analysis
Fitzpatrick JM, Roberts DW, Patlewicz G . 2017. What determines skin sensitization potency–Myths, maybes and realities. The 500 molecular weight cut-off – An updated analysis. J Appl Toxicol 37(1):105-116; doi: 10.1002/jat.3348 . PMID: 27283458.
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Topics: Exposure Assessment
Fitzpatrick JM, Roberts DW, Patlewicz G . 2017. Is skin penetration a determining factor in skin sensitization potential and potency? Refuting the notion of a LogKow threshold for skin sensitization. J Appl Toxicol 37(1):117-127; doi: 10.1002/jat.3354 . PMID: 27357739.
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